JP2012505665A - 脂肪組織から細胞集団を得る方法 - Google Patents

脂肪組織から細胞集団を得る方法 Download PDF

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JP2012505665A
JP2012505665A JP2011532316A JP2011532316A JP2012505665A JP 2012505665 A JP2012505665 A JP 2012505665A JP 2011532316 A JP2011532316 A JP 2011532316A JP 2011532316 A JP2011532316 A JP 2011532316A JP 2012505665 A JP2012505665 A JP 2012505665A
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cells
population
cell
adipose tissue
certain embodiments
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JP2012505665A5 (cg-RX-API-DMAC10.html
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アンソニー ドノフリオ，
ディレーラ モトラグ，
デイビッド エル． アムラニ，
エイミー コーエン，
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Baxter Healthcare SA
Baxter International Inc
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Baxter International Inc
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653—Adipocytes; Adipose tissue
    • A—HUMAN NECESSITIES
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    • C12N2509/00—Methods for the dissociation of cells, e.g. specific use of enzymes

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JP2011532316A 2008-10-17 2009-10-19 脂肪組織から細胞集団を得る方法 Pending JP2012505665A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10635308P 2008-10-17 2008-10-17
US61/106,353 2008-10-17
PCT/US2009/061185 WO2010045645A1 (en) 2008-10-17 2009-10-19 Methods of obtaining cell populations from adipose tissue

Publications (2)

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JP2012505665A true JP2012505665A (ja) 2012-03-08
JP2012505665A5 JP2012505665A5 (cg-RX-API-DMAC10.html) 2012-12-06

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US (1) US20110274667A1 (cg-RX-API-DMAC10.html)
EP (1) EP2356214A1 (cg-RX-API-DMAC10.html)
JP (1) JP2012505665A (cg-RX-API-DMAC10.html)
CN (1) CN102186968A (cg-RX-API-DMAC10.html)
AU (1) AU2009305532A1 (cg-RX-API-DMAC10.html)
CA (1) CA2740578A1 (cg-RX-API-DMAC10.html)
WO (1) WO2010045645A1 (cg-RX-API-DMAC10.html)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016017068A (ja) * 2014-07-10 2016-02-01 国立大学法人金沢大学 脂肪組織由来間質細胞群を含む消化管炎症治療剤
WO2017141831A1 (ja) * 2016-02-16 2017-08-24 ロート製薬株式会社 脂肪組織由来間質細胞を含む虚血性疾患治療剤およびその製造方法
JP2018533926A (ja) * 2015-10-08 2018-11-22 高雄醫學大學 脂肪間質細胞を急速分離する組成物

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9234897B2 (en) * 2005-03-31 2016-01-12 Two Cells Co., Ltd Method for distinguishing mesenchymal stem cell using molecular marker and use thereof
JP2015508101A (ja) 2012-02-21 2015-03-16 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ Ｃｄ３４＋細胞を含む薬学的組成物
WO2014089554A1 (en) * 2012-12-07 2014-06-12 Antria, Inc. Formulations containing and kit for using adipose-derived stem cells and use thereof
FR3024778B1 (fr) * 2014-08-05 2021-01-22 Screencell Procede pour le depistage de la drepanocytose et kit pour sa mise en oeuvre
EP3478300B1 (en) 2016-06-30 2022-08-24 Stem Cell Medicine Ltd. Treatment of inflammatory bowel disease with long acting glatiramer and adipose-derived stem cells
CN106337036A (zh) * 2016-08-26 2017-01-18 杭州易文赛生物技术有限公司 一种提高脂肪组织中cd34阳性血管基质成分提取率的方法
CN106399234A (zh) * 2016-08-31 2017-02-15 肖锷 脂肪组织的处理方法及间充质干细胞、处理后单个脂肪细胞和细胞外基质
EP3624815A4 (en) 2017-05-15 2021-01-20 Stem Cell Medicine Ltd. TREATMENT OF MULTIPLE SCLEROSIS WITH LONG-ACTING GLATIRAMER AND ADAPTIVE STEM CELLS
IL269893B2 (en) 2017-05-15 2023-10-01 Stem Cell Medicine Ltd Treatment of multiple sclerosis with adipose-derived stem cells
CN108261424B (zh) * 2018-01-24 2020-11-06 中国医学科学院医药生物技术研究所 一种肝癌的生物治疗方法
US20210369608A1 (en) * 2018-02-23 2021-12-02 Regeneration Biomedical, Inc. Methods, apparatuses and systems for instilling stem cells and pharmaceuticals into the human ventricular system
CN111518761B (zh) * 2020-05-25 2022-04-29 青岛瑞思德生物科技有限公司 一种间充质干细胞体外筛选、激活、扩增、冻存及其细胞库建立的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09508534A (ja) * 1994-06-14 1997-09-02 バクスター インターナショナル インコーポレイテッド ペプチド放出により媒介されるポジティブ細胞選択およびポジティブ／ネガティブ細胞選択
WO2007103379A2 (en) * 2006-03-07 2007-09-13 Humacyte Method for endothelial cell extraction from adipose tissues

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808532A (en) * 1985-07-01 1989-02-28 The United States Of America As Represented By The United States Department Of Energy Continuous human cell lines and method of making same
JP2008528041A (ja) * 2005-01-31 2008-07-31 コグネート セラピューティクス，インコーポレーテッド 内皮細胞の性質を示す脂肪由来成体間質細胞

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09508534A (ja) * 1994-06-14 1997-09-02 バクスター インターナショナル インコーポレイテッド ペプチド放出により媒介されるポジティブ細胞選択およびポジティブ／ネガティブ細胞選択
WO2007103379A2 (en) * 2006-03-07 2007-09-13 Humacyte Method for endothelial cell extraction from adipose tissues

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN5012003217; ＦＲＡＳＥＲ，　Ｊ．Ｋ．，　ｅｔ　ａｌ．: 'ＤＩＦＦＥＲＥＮＣＥＳ　ＩＮ　ＳＴＥＭ　ＡＮＤ　ＰＲＯＧＥＮＩＴＯＲ　ＣＥＬＬ　ＹＩＥＬＤ　ＩＮ　ＤＩＦＦＥＲＥＮＴ　ＳＵＢＣＵＴＡＮＥＯＵＳ　ＡＤＩＰＯＳＥ　ＴＩＳＳＵＥ　ＤＥＰＯＴＳ' ＣＹＴＯＴＨＥＲＡＰＹ ９（５）, 2007, ｐｐ．４５９-４６７ *
JPN5012003219; ＦＲＡＳＥＲ，　Ｊ．Ｋ，　ｅｔ　ａｌ．: 'ＡＤＩＰＯＳＥ-ＤＥＲＩＶＥＤ　ＳＴＥＭ　ＣＥＬＬＳ' ＭＥＴＨＯＤＳ　ＩＮ　ＭＯＬＥＣＵＬＡＲ　ＢＩＯＬＯＧＹ ４４９, 200809, ｐｐ．５９-６７ *
JPN6014014858; ＹＯＳＨＩＭＵＲＡ，　Ｋ．，　ｅｔ　ａｌ．: ＪＯＵＲＮＡＬ　ＯＦ　ＣＥＬＬＵＬＡＲ　ＰＨＹＳＩＯＬＯＧＹ ２０８, 2006, ｐｐ．６４-７６ *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016017068A (ja) * 2014-07-10 2016-02-01 国立大学法人金沢大学 脂肪組織由来間質細胞群を含む消化管炎症治療剤
JP2018533926A (ja) * 2015-10-08 2018-11-22 高雄醫學大學 脂肪間質細胞を急速分離する組成物
WO2017141831A1 (ja) * 2016-02-16 2017-08-24 ロート製薬株式会社 脂肪組織由来間質細胞を含む虚血性疾患治療剤およびその製造方法
JPWO2017141831A1 (ja) * 2016-02-16 2018-12-06 ロート製薬株式会社 脂肪組織由来間質細胞を含む虚血性疾患治療剤およびその製造方法
JP7372736B2 (ja) 2016-02-16 2023-11-01 ロート製薬株式会社 脂肪組織由来間質細胞を含む虚血性疾患治療剤およびその製造方法

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CN102186968A (zh) 2011-09-14
US20110274667A1 (en) 2011-11-10
CA2740578A1 (en) 2010-04-22
AU2009305532A1 (en) 2010-04-22
EP2356214A1 (en) 2011-08-17
WO2010045645A1 (en) 2010-04-22

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