JP2012504649A5 - - Google Patents
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- JP2012504649A5 JP2012504649A5 JP2011530261A JP2011530261A JP2012504649A5 JP 2012504649 A5 JP2012504649 A5 JP 2012504649A5 JP 2011530261 A JP2011530261 A JP 2011530261A JP 2011530261 A JP2011530261 A JP 2011530261A JP 2012504649 A5 JP2012504649 A5 JP 2012504649A5
- Authority
- JP
- Japan
- Prior art keywords
- rifaximin
- subject
- administration
- episodes
- risk
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10234908P | 2008-10-02 | 2008-10-02 | |
| US61/102,349 | 2008-10-02 | ||
| PCT/US2009/059321 WO2010040020A1 (en) | 2008-10-02 | 2009-10-02 | Methods of treating hepatic encephalopathy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015103724A Division JP2015166381A (ja) | 2008-10-02 | 2015-05-21 | 肝性脳症を治療する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012504649A JP2012504649A (ja) | 2012-02-23 |
| JP2012504649A5 true JP2012504649A5 (enExample) | 2012-11-22 |
| JP6037615B2 JP6037615B2 (ja) | 2016-12-07 |
Family
ID=42073897
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011530261A Active JP6037615B2 (ja) | 2008-10-02 | 2009-10-02 | 肝性脳症を治療する方法 |
| JP2015103724A Pending JP2015166381A (ja) | 2008-10-02 | 2015-05-21 | 肝性脳症を治療する方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015103724A Pending JP2015166381A (ja) | 2008-10-02 | 2015-05-21 | 肝性脳症を治療する方法 |
Country Status (21)
| Country | Link |
|---|---|
| US (12) | US20100204173A1 (enExample) |
| EP (4) | EP3628319B1 (enExample) |
| JP (2) | JP6037615B2 (enExample) |
| CN (1) | CN102245615A (enExample) |
| AU (1) | AU2009298389C1 (enExample) |
| BR (1) | BRPI0920465A2 (enExample) |
| CA (1) | CA2739436C (enExample) |
| CY (1) | CY1122806T1 (enExample) |
| DK (2) | DK3628319T3 (enExample) |
| ES (2) | ES2972135T3 (enExample) |
| FI (1) | FI3628319T3 (enExample) |
| HR (2) | HRP20240317T1 (enExample) |
| HU (2) | HUE048293T2 (enExample) |
| IL (1) | IL212055A0 (enExample) |
| LT (2) | LT2350096T (enExample) |
| MX (2) | MX364102B (enExample) |
| PL (2) | PL2350096T3 (enExample) |
| PT (2) | PT2350096T (enExample) |
| SI (2) | SI2350096T1 (enExample) |
| SM (2) | SMT202400116T1 (enExample) |
| WO (1) | WO2010040020A1 (enExample) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| DK1698630T3 (da) | 2005-03-03 | 2014-12-08 | Alfa Wassermann Spa | Nye polymorfe former af rifaximin, fremgangsmåde for deres fremstilling og anvendelse deraf i de medicinske præparater |
| US12285414B2 (en) | 2008-10-02 | 2025-04-29 | Salix Pharmaceuticals, Inc. | Methods of treating hepatic encephalopathy |
| MX364102B (es) | 2008-10-02 | 2019-04-12 | Salix Pharmaceuticals Ltd | Medicamentos para usarse en el tratamiento de la encefalopatía hepática. |
| US20110035232A1 (en) * | 2008-10-02 | 2011-02-10 | Salix Pharmaceuticals, Ltd. | Methods of treating hepatic encephalopathy |
| US7928115B2 (en) | 2008-10-02 | 2011-04-19 | Salix Pharmaceuticals, Ltd. | Methods of treating travelers diarrhea and hepatic encephalopathy |
| BRPI1010028A2 (pt) * | 2009-06-02 | 2019-02-12 | Salix Pharmaceuticals, Ltd. | métodos de tratamento de encefalopatia hepática |
| RU2571268C2 (ru) * | 2009-06-15 | 2015-12-20 | Саликс Фармасьютикалз, Лтд. | Модуляция системного воздействия рифаксимина |
| CA2778181C (en) | 2009-10-26 | 2024-05-28 | Thomas Julius Borody | Therapy for enteric infections |
| AU2011286165B2 (en) | 2010-08-04 | 2016-10-20 | Thomas Julius Borody | Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them |
| WO2012076832A1 (en) * | 2010-12-09 | 2012-06-14 | Cipla Limited | Suppositories comprising rifaximin |
| BR112013022927A2 (pt) | 2011-03-09 | 2016-12-06 | Univ Minnesota | composição, métodos para substituir ou suplementar ou modificar uma microbiota do cólon de um sujeito, e para tratar um sujeito, e, uso de uma composição |
| PL2773205T3 (pl) | 2011-11-02 | 2024-09-02 | Salix Pharmaceuticals, Inc. | Ryfaksymina w leczeniu ustępującej biegunki z przewagą zespołu jelita drażliwego |
| US9719144B2 (en) | 2012-05-25 | 2017-08-01 | Arizona Board Of Regents | Microbiome markers and therapies for autism spectrum disorders |
| ITBO20120368A1 (it) * | 2012-07-06 | 2014-01-07 | Alfa Wassermann Spa | Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso. |
| MX2015003107A (es) * | 2012-09-13 | 2015-09-10 | Salix Pharmaceuticals Inc | Metodos para mejorar la supervivencia a largo plazo y reducir los porcentajes de readmision a hospitalizacion para personas que padecen encefalopatia hepatica. |
| US9265458B2 (en) | 2012-12-04 | 2016-02-23 | Sync-Think, Inc. | Application of smooth pursuit cognitive testing paradigms to clinical drug development |
| WO2014107657A2 (en) * | 2013-01-04 | 2014-07-10 | Kohn Kenneth I | Cholesterol-lowering compounds in combination with lipid metabolism-altering compounds of non-absorbable sugars, compounds that convert nh3 to nh4+, or hydrogen-generating compounds for the treatment of high cholesterol and inflammation |
| US9380976B2 (en) | 2013-03-11 | 2016-07-05 | Sync-Think, Inc. | Optical neuroinformatics |
| US9492535B2 (en) | 2013-03-14 | 2016-11-15 | Aimmune Therapeutics, Inc. | Peanut formulations and uses thereof |
| WO2014176632A1 (en) * | 2013-04-30 | 2014-11-06 | Borody Thomas J | Compositions and methods for treating microbiota-related psychotropic conditions and diseases |
| CN103340856A (zh) * | 2013-07-09 | 2013-10-09 | 荣港生技医药科技(北京)有限公司 | 一种利福昔明药物组合物及其制备方法 |
| US20160339040A1 (en) | 2014-01-29 | 2016-11-24 | Umecrine Cognition Ab | Steroid compound for use in the treatment of hepatic encephalopathy |
| ES2621557T3 (es) | 2014-03-31 | 2017-07-04 | Euticals S.P.A. | Mezcla polimórfica de rifaximina y su uso para la preparación de formulaciones sólidas |
| PL3143027T3 (pl) | 2014-05-12 | 2019-11-29 | Alfasigma Spa | Nowe solwatowane krystaliczne postaci rifaksyminy, ich wytwarzanie, kompozycje i zastosowania |
| CN106999477B (zh) * | 2014-06-30 | 2020-04-10 | 萨利克斯药品公司 | 用于重复治疗肠易激综合征(ibs)的方法 |
| TWI748936B (zh) | 2015-01-12 | 2021-12-11 | 瑞典商優鎂奎認知Ab公司 | 新穎化合物 |
| KR20180026376A (ko) | 2015-05-14 | 2018-03-12 | 크레스토보 홀딩스 엘엘씨 | 대변 균무리 이식용 조성물, 및 이의 제조 및 사용 방법, 및 이의 전달을 위한 장치 |
| DK3297644T3 (da) | 2015-05-22 | 2022-04-11 | Univ Arizona State | Fremgangsmåder til behandling af autismespektrumforstyrrelse og forbundne symptomer |
| CA3010865A1 (en) * | 2016-01-08 | 2017-07-13 | Colonaryconcepts Llc | Food based delivery of therapeutic agent for treatment of hepatic encephalopathy |
| US20170360848A1 (en) | 2016-06-15 | 2017-12-21 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods for treating autism spectrum disorder and associated symptoms |
| US10849936B2 (en) | 2016-07-01 | 2020-12-01 | Regents Of The University Of Minnesota | Compositions and methods for C. difficile treatment |
| US20180036352A1 (en) | 2016-08-03 | 2018-02-08 | Crestovo Holdings Llc | Methods for treating ulcerative colitis |
| CN110072525B (zh) | 2016-09-30 | 2022-12-02 | 萨利克斯药品公司 | 利福昔明的固态分散形式 |
| US10092601B2 (en) | 2016-10-11 | 2018-10-09 | Crestovo Holdings Llc | Compositions and methods for treating multiple sclerosis and related disorders |
| US11026978B2 (en) | 2016-10-11 | 2021-06-08 | Finch Therapeutics Holdings Llc | Compositions and methods for treating multiple sclerosis and related disorders |
| US11213549B2 (en) | 2016-10-11 | 2022-01-04 | Finch Therapeutics Holdings Llc | Compositions and method for treating primary sclerosing cholangitis and related disorders |
| CN106822125A (zh) * | 2017-02-28 | 2017-06-13 | 丹诺医药(苏州)有限公司 | 一种利福霉素‑喹嗪酮双靶标分子的新用途 |
| CN106822119A (zh) * | 2017-02-28 | 2017-06-13 | 丹诺医药(苏州)有限公司 | 一种利福霉素‑硝基咪唑偶联分子的新用途 |
| US11040073B2 (en) | 2017-04-05 | 2021-06-22 | Finch Therapeutics Holdings Llc | Compositions and methods for treating diverticulitis and related disorders |
| CN110831606A (zh) | 2017-04-05 | 2020-02-21 | 克雷斯顿沃控股公司 | 治疗帕金森氏病(pd)和相关疾病的组合物和方法 |
| CN110996917A (zh) | 2017-05-26 | 2020-04-10 | 克雷斯顿沃控股公司 | 包含基于粪便微生物的治疗剂的冻干组合物及其制造和使用方法 |
| EP3664823B1 (en) | 2017-08-07 | 2024-06-05 | Finch Therapeutics Holdings LLC | Composition for use in preventing or treating an enterococcal blood stream infection |
| AR114140A1 (es) | 2017-11-10 | 2020-07-29 | Cosmo Technologies Ltd | Composiciones orales de rifamicina sv |
| US11166990B2 (en) | 2018-07-13 | 2021-11-09 | Finch Therapeutics Holdings Llc | Methods and compositions for treating ulcerative colitis |
| US12433945B2 (en) | 2018-08-16 | 2025-10-07 | Société des Produits Nestlé S.A. | Peanut oral immunotherapy with maintenance dose |
| WO2020069280A1 (en) | 2018-09-27 | 2020-04-02 | Crestovo Holdings Llc | Compositions and methods for treating epilepsy and related disorders |
| US12226448B2 (en) | 2018-12-20 | 2025-02-18 | Société des Produits Nestlé S.A. | Peanut oral immunotherapy dosing schedule for missed doses |
| EP3965815A4 (en) | 2019-05-10 | 2023-05-31 | Société des Produits Nestlé S.A. | METHOD OF IMPROVING THE QUALITY OF LIFE IN A PEANUT ALLERGY PATIENT |
| WO2020245214A1 (en) * | 2019-06-03 | 2020-12-10 | Bausch Health Ireland Limited | Use of methylnaltrexone and rifaximin for treatment of increased gut permeability or associated disorders |
| JP2022541795A (ja) | 2019-07-19 | 2022-09-27 | フィンチ セラピューティクス ホールディングス エルエルシー | 胃腸障害の治療のための方法および産物 |
| CN115715193A (zh) * | 2020-03-24 | 2023-02-24 | 博士医疗爱尔兰有限公司 | 用于治疗显性肝性脑病的利福昔明的固体分散体 |
| US20250345400A1 (en) * | 2022-05-18 | 2025-11-13 | Virginia Commonwealth University | Methods for treatment of cognitive impairment in cirrhosis patients |
| WO2025064599A1 (en) * | 2023-09-19 | 2025-03-27 | The United States Government As Represented By The Department Of Veterans Affairs | Rifamycin composition for treating sarcopenia |
| WO2025157240A1 (zh) * | 2024-01-26 | 2025-07-31 | 丹诺医药(苏州)股份有限公司 | 化合物用于制备治疗细菌代谢相关疾病的药物的用途 |
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| WO1994008599A1 (en) | 1992-10-14 | 1994-04-28 | The Regents Of The University Of Colorado | Ion-pairing of drugs for improved efficacy and delivery |
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| US20090149453A1 (en) * | 2002-05-23 | 2009-06-11 | Activbiotics Pharma Llc | Methods and compositions for treating bacterial infections and diseases associated therewith |
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2009
- 2009-10-02 MX MX2014013652A patent/MX364102B/es unknown
- 2009-10-02 HU HUE09818544A patent/HUE048293T2/hu unknown
- 2009-10-02 ES ES19207534T patent/ES2972135T3/es active Active
- 2009-10-02 WO PCT/US2009/059321 patent/WO2010040020A1/en not_active Ceased
- 2009-10-02 LT LTEP09818544.0T patent/LT2350096T/lt unknown
- 2009-10-02 ES ES09818544T patent/ES2770308T3/es active Active
- 2009-10-02 EP EP19207534.9A patent/EP3628319B1/en active Active
- 2009-10-02 PL PL09818544T patent/PL2350096T3/pl unknown
- 2009-10-02 SI SI200932045T patent/SI2350096T1/sl unknown
- 2009-10-02 PT PT98185440T patent/PT2350096T/pt unknown
- 2009-10-02 DK DK19207534.9T patent/DK3628319T3/da active
- 2009-10-02 LT LTEP19207534.9T patent/LT3628319T/lt unknown
- 2009-10-02 DK DK09818544.0T patent/DK2350096T3/da active
- 2009-10-02 EP EP24155114.2A patent/EP4342465A3/en active Pending
- 2009-10-02 FI FIEP19207534.9T patent/FI3628319T3/fi active
- 2009-10-02 SM SM20240116T patent/SMT202400116T1/it unknown
- 2009-10-02 SI SI200932192T patent/SI3628319T1/sl unknown
- 2009-10-02 HR HRP20240317TT patent/HRP20240317T1/hr unknown
- 2009-10-02 EP EP09818544.0A patent/EP2350096B1/en not_active Revoked
- 2009-10-02 PT PT192075349T patent/PT3628319T/pt unknown
- 2009-10-02 CN CN2009801490791A patent/CN102245615A/zh active Pending
- 2009-10-02 JP JP2011530261A patent/JP6037615B2/ja active Active
- 2009-10-02 MX MX2011003548A patent/MX2011003548A/es active IP Right Grant
- 2009-10-02 PL PL19207534.9T patent/PL3628319T3/pl unknown
- 2009-10-02 EP EP25177992.2A patent/EP4591862A3/en active Pending
- 2009-10-02 HR HRP20200284TT patent/HRP20200284T1/hr unknown
- 2009-10-02 AU AU2009298389A patent/AU2009298389C1/en active Active
- 2009-10-02 BR BRPI0920465-2A patent/BRPI0920465A2/pt not_active Application Discontinuation
- 2009-10-02 HU HUE19207534A patent/HUE065491T2/hu unknown
- 2009-10-02 CA CA2739436A patent/CA2739436C/en active Active
- 2009-10-02 SM SM20200124T patent/SMT202000124T1/it unknown
- 2009-10-02 US US12/572,344 patent/US20100204173A1/en not_active Abandoned
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2011
- 2011-03-31 US US13/077,373 patent/US20110243879A1/en not_active Abandoned
- 2011-03-31 IL IL212055A patent/IL212055A0/en active IP Right Grant
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2013
- 2013-02-15 US US13/768,617 patent/US8969398B2/en active Active
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2015
- 2015-02-03 US US14/612,697 patent/US9629829B2/en active Active
- 2015-05-21 JP JP2015103724A patent/JP2015166381A/ja active Pending
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2017
- 2017-03-16 US US15/460,704 patent/US9949958B2/en active Active
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2018
- 2018-03-15 US US15/922,010 patent/US10335397B2/en active Active
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2019
- 2019-05-16 US US16/414,018 patent/US10709694B2/en active Active
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2020
- 2020-02-21 CY CY20201100167T patent/CY1122806T1/el unknown
- 2020-06-05 US US16/893,651 patent/US20200368213A1/en not_active Abandoned
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2021
- 2021-03-26 US US17/213,678 patent/US11633384B2/en active Active
-
2023
- 2023-03-06 US US18/117,899 patent/US20240066010A1/en not_active Abandoned
- 2023-04-18 US US18/135,823 patent/US20230330071A1/en not_active Abandoned
-
2024
- 2024-05-17 US US18/667,886 patent/US20240299368A1/en active Pending
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