JP2012224636A5 - - Google Patents
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- Publication number
- JP2012224636A5 JP2012224636A5 JP2012166700A JP2012166700A JP2012224636A5 JP 2012224636 A5 JP2012224636 A5 JP 2012224636A5 JP 2012166700 A JP2012166700 A JP 2012166700A JP 2012166700 A JP2012166700 A JP 2012166700A JP 2012224636 A5 JP2012224636 A5 JP 2012224636A5
- Authority
- JP
- Japan
- Prior art keywords
- glucan
- conjugate according
- conjugate
- laminarin
- bacterial toxoid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 claims 21
- 229920002498 Beta-glucan Polymers 0.000 claims 19
- 229920001503 Glucan Polymers 0.000 claims 5
- 230000001580 bacterial effect Effects 0.000 claims 5
- DBTMGCOVALSLOR-DEVYUCJPSA-N (2s,3r,4s,5r,6r)-4-[(2s,3r,4s,5r,6r)-3,5-dihydroxy-6-(hydroxymethyl)-4-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)oxane-2,3,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](CO)O[C@H](O)[C@@H]2O)O)O[C@H](CO)[C@H]1O DBTMGCOVALSLOR-DEVYUCJPSA-N 0.000 claims 4
- 229920001543 Laminarin Polymers 0.000 claims 4
- 239000005717 Laminarin Substances 0.000 claims 4
- 230000002538 fungal effect Effects 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 3
- 229960005486 vaccine Drugs 0.000 claims 3
- 241000222120 Candida <Saccharomycetales> Species 0.000 claims 2
- 108091005804 Peptidases Proteins 0.000 claims 2
- 239000004365 Protease Substances 0.000 claims 2
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 2
- 230000001681 protective effect Effects 0.000 claims 2
- 102100024023 Histone PARylation factor 1 Human genes 0.000 claims 1
- 101001047783 Homo sapiens Histone PARylation factor 1 Proteins 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 230000003213 activating effect Effects 0.000 claims 1
- 239000002671 adjuvant Substances 0.000 claims 1
- 229940121375 antifungal agent Drugs 0.000 claims 1
- 239000003429 antifungal agent Substances 0.000 claims 1
- 210000002421 cell wall Anatomy 0.000 claims 1
- 244000053095 fungal pathogen Species 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0211118.5 | 2002-05-15 | ||
| GBGB0211118.5A GB0211118D0 (en) | 2002-05-15 | 2002-05-15 | Vaccines |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009294467A Division JP2010131017A (ja) | 2002-05-15 | 2009-12-25 | グルカンベースのワクチン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012224636A JP2012224636A (ja) | 2012-11-15 |
| JP2012224636A5 true JP2012224636A5 (enExample) | 2013-07-18 |
| JP5684758B2 JP5684758B2 (ja) | 2015-03-18 |
Family
ID=9936711
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004505087A Expired - Fee Related JP5110767B2 (ja) | 2002-05-15 | 2003-05-15 | グルカンベースのワクチン |
| JP2009294467A Pending JP2010131017A (ja) | 2002-05-15 | 2009-12-25 | グルカンベースのワクチン |
| JP2012166700A Expired - Fee Related JP5684758B2 (ja) | 2002-05-15 | 2012-07-27 | グルカンベースのワクチン |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004505087A Expired - Fee Related JP5110767B2 (ja) | 2002-05-15 | 2003-05-15 | グルカンベースのワクチン |
| JP2009294467A Pending JP2010131017A (ja) | 2002-05-15 | 2009-12-25 | グルカンベースのワクチン |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US20050208079A1 (enExample) |
| EP (2) | EP1506009B1 (enExample) |
| JP (3) | JP5110767B2 (enExample) |
| AT (2) | ATE497781T1 (enExample) |
| AU (1) | AU2003241104A1 (enExample) |
| CA (2) | CA2830619A1 (enExample) |
| CY (1) | CY1108234T1 (enExample) |
| DE (2) | DE60336027D1 (enExample) |
| DK (1) | DK1506009T3 (enExample) |
| ES (1) | ES2306871T3 (enExample) |
| GB (1) | GB0211118D0 (enExample) |
| PT (1) | PT1506009E (enExample) |
| SI (1) | SI1506009T1 (enExample) |
| WO (1) | WO2003097091A2 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7507724B2 (en) * | 2001-01-16 | 2009-03-24 | Sloan-Kettering Institute For Cancer Research | Therapy-enhancing glucan |
| US7906492B2 (en) | 2001-01-16 | 2011-03-15 | Sloan-Kettering Institute For Cancer Research | Therapy-enhancing glucan |
| US8071552B2 (en) * | 2004-04-05 | 2011-12-06 | Universite Bordeaux 2 | Peptides and peptidomimetics binding to CD23 |
| GB0420466D0 (en) | 2004-09-14 | 2004-10-20 | Cassone Antonio | Anti-glucan antibodies |
| HUE045482T2 (hu) | 2005-06-27 | 2019-12-30 | Glaxosmithkline Biologicals Sa | Immunogén készítmény |
| US8323644B2 (en) * | 2006-01-17 | 2012-12-04 | Sloan-Kettering Institute For Cancer Research | Therapy-enhancing glucan |
| JP2009528267A (ja) * | 2006-01-17 | 2009-08-06 | スローン − ケッタリング インスティチュート フォー キャンサー リサーチ | 治療を増強するグルカン |
| US20090053221A1 (en) * | 2006-01-17 | 2009-02-26 | Cheung Nai-Kong V | Immune response enhancing glucan |
| US20070253985A1 (en) * | 2006-04-26 | 2007-11-01 | Wyeth | Novel processes for coating container means which inhibit precipitation of polysaccharide-protein conjugate formulations |
| WO2008057501A2 (en) * | 2006-11-06 | 2008-05-15 | Whitehead Institute | Immunomodulating compositions and methods of use thereof |
| US9457047B2 (en) | 2006-11-06 | 2016-10-04 | Whitehead Institute | Immunomodulating compositions and methods of use thereof |
| AU2013203785B2 (en) * | 2006-11-06 | 2016-11-17 | Immunexcite, Inc. | Immunomodulating compositions and methods of use thereof |
| JP4687644B2 (ja) | 2006-12-22 | 2011-05-25 | 富士ゼロックス株式会社 | 画像処理装置、画像読取装置及び画像形成装置 |
| WO2009068996A2 (en) * | 2007-11-26 | 2009-06-04 | Novartis Ag | Conjugated beta-1,3-linked glucans |
| CA2706617A1 (en) * | 2007-11-26 | 2009-06-25 | Novartis Ag | Adjuvanted glucans |
| EP2283358B1 (en) * | 2008-04-29 | 2015-04-22 | Immunexcite, Inc. | Immunomodulating compositions and methods of use thereof |
| NZ591768A (en) | 2008-09-18 | 2012-11-30 | Novartis Ag | Vaccine adjuvant combinations |
| NL1036661C2 (en) | 2009-03-04 | 2010-09-07 | Serrix B V | Anti-fungal compounds & compositions. |
| US20120124703A1 (en) * | 2009-03-10 | 2012-05-17 | Palmed Teva Ltd | Novel coprinus comatus and tremella mesenterica mushroom strains, products and extracts thereof and compositions comprising them |
| AU2010288239B2 (en) | 2009-08-27 | 2014-01-16 | Novartis Ag | Adjuvant comprising aluminium, oligonucleotide and polycation |
| US9950062B2 (en) | 2009-09-02 | 2018-04-24 | Glaxosmithkline Biologicals Sa | Compounds and compositions as TLR activity modulators |
| WO2011035205A2 (en) | 2009-09-18 | 2011-03-24 | Calmune Corporation | Antibodies against candida, collections thereof and methods of use |
| CN102939537B (zh) * | 2010-05-14 | 2016-09-14 | 全技术公司 | 酵母细胞壁组分及其检测 |
| JP2013538217A (ja) | 2010-09-01 | 2013-10-10 | ノバルティス アーゲー | 不溶性金属塩への免疫増強物質の吸着 |
| ES2630029T3 (es) | 2010-12-14 | 2017-08-17 | Glaxosmithkline Biologicals Sa | Análisis de citometría de flujo de materiales adsorbidos en sales metálicas |
| CN103533954B (zh) | 2011-03-02 | 2015-09-09 | 诺华股份有限公司 | 含较低剂量的抗原和/或佐剂的联合疫苗 |
| CN103764171B (zh) | 2011-07-08 | 2016-08-17 | 诺华股份有限公司 | 酪氨酸连接方法 |
| RU2636350C2 (ru) | 2011-11-07 | 2017-11-22 | Новартис Аг | МОЛЕКУЛА, СОДЕРЖАЩАЯ SPR0096 и SPR2021 |
| WO2013131983A1 (en) | 2012-03-07 | 2013-09-12 | Novartis Ag | Adjuvanted formulations of streptococcus pneumoniae antigens |
| RU2014140336A (ru) | 2012-03-07 | 2016-04-27 | Новартис Аг | Иммунологически полезные соли аргинина |
| CA2866406A1 (en) | 2012-03-08 | 2013-09-12 | Novartis Ag | Adjuvanted formulations of booster vaccines |
| KR102103366B1 (ko) * | 2012-04-30 | 2020-04-22 | 바이오테라, 인크. | β-글루칸 면역치료 방법 |
| US9827190B2 (en) | 2013-02-01 | 2017-11-28 | Glaxosmithkline Biologicals Sa | Intradermal delivery of immunological compositions comprising toll-like receptor 7 agonists |
| CN103083663B (zh) * | 2013-02-04 | 2014-12-10 | 江苏省农业科学院 | 一种免疫增强剂、灭活疫苗及其制备方法 |
| FI2968427T3 (fi) | 2013-03-12 | 2023-03-01 | Konjugaatti sienisoluseinämän polysakkarideihin kohdentuvien vasta-aineiden indusoimiseksi | |
| KR20160040556A (ko) | 2013-07-11 | 2016-04-14 | 노파르티스 아게 | 미생물 트랜스글루타미나제를 사용한 리신-특이적 화학효소적 단백질 변형 |
| EP3077816B1 (en) * | 2013-12-05 | 2021-03-24 | Biothera, Inc. | Beta-glucan assay methods |
| EP3862002A1 (en) * | 2015-01-26 | 2021-08-11 | Kaleido Biosciences, Inc. | Glycan therapeutics and related methods thereof |
| CN104771498A (zh) * | 2015-03-13 | 2015-07-15 | 臧海阳 | 一种治疗热毒蕴结型痄腮的中药组合物 |
| WO2018156888A1 (en) | 2017-02-24 | 2018-08-30 | Biothera Pharmaceuticals, Inc. | Beta glucan immunopharmacodynamics |
| CN111684061B (zh) * | 2018-01-19 | 2024-07-30 | 美天施生物科技有限两合公司 | 表达嵌合抗原受体的调节性t细胞 |
| US11701417B2 (en) * | 2019-03-27 | 2023-07-18 | West Virginia University | Vaccine formulation to protect against pertussis |
| WO2023002252A1 (en) | 2021-07-21 | 2023-01-26 | Bioatlantis Limited | Composition comprising beta-glucans and alpha-fucans for improving gut health and animal performance and methods of making the same |
| JP2025507875A (ja) | 2022-02-28 | 2025-03-21 | トライデム バイオサイエンス ゲーエムベーハー ウント コンパニー カーゲー | 少なくともβ－グルカン若しくはマンナンからなるか、又はこれを含む結合体 |
| CN119136838A (zh) * | 2022-02-28 | 2024-12-13 | 特瑞德姆生物科技有限责任两合公司 | 由至少一种β-葡聚糖或甘露聚糖组成或包含至少一种β-葡聚糖或甘露聚糖的偶联物 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE466289B (sv) | 1984-09-19 | 1992-01-27 | James Hoffman | Makrofagstimulerande komposition jaemte foerfarande foer dess framstaellning |
| JPS6383012A (ja) * | 1986-09-26 | 1988-04-13 | Nonogawa Shoji:Kk | 化粧料 |
| EP0490995A1 (en) * | 1989-09-08 | 1992-06-24 | Alpha Beta Technology | Method for producing soluble glucans |
| EP0471954A3 (en) * | 1990-08-13 | 1993-03-03 | American Cyanamid Company | Immunogenic conjugates of nontoxic oligosaccharide derived from bordetella pertussis lipooligosaccharide |
| US5153312A (en) * | 1990-09-28 | 1992-10-06 | American Cyanamid Company | Oligosaccharide conjugate vaccines |
| DK0616034T3 (da) * | 1993-03-05 | 2005-02-21 | Wyeth Corp | Plasmid til fremstilling af CRM-protein og diphtheria toxin |
| CN1094288A (zh) * | 1993-04-23 | 1994-11-02 | 福建省微生物研究所 | 利用红色诺卡氏菌制造细胞壁骨架粉末的方法 |
| NO300692B1 (no) | 1994-04-29 | 1997-07-07 | Biotec Mackzymal As | Solubilisert forgrenet ß-1,3-glukan og anvendelse derav samt anvendelse av usolubilisert forgrenet ß-1,3-glukan |
| US6309642B1 (en) * | 1997-04-28 | 2001-10-30 | The Research And Development Institute, Inc. | Peptides which mimic candida carbohydrate epitopes and their use in a vaccine |
| AUPN166195A0 (en) * | 1995-03-13 | 1995-04-06 | Norvet Research Pty Limited | Process for glucan extraction |
| JPH09309842A (ja) * | 1996-05-20 | 1997-12-02 | Kureha Chem Ind Co Ltd | 新規な生理活性物質、その製造方法及び医薬組成物 |
| US6573245B1 (en) * | 1998-04-28 | 2003-06-03 | Galenica Pharmaceuticals, Inc. | Modified polysaccharide adjuvant-protein antigen conjugates, the preparation thereof and the use thereof |
| US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
| GB9925559D0 (en) * | 1999-10-28 | 1999-12-29 | Smithkline Beecham Biolog | Novel method |
| JP4230635B2 (ja) | 2000-02-29 | 2009-02-25 | 富士フイルム株式会社 | デジタルカメラ |
-
2002
- 2002-05-15 GB GBGB0211118.5A patent/GB0211118D0/en not_active Ceased
-
2003
- 2003-05-15 AT AT07075796T patent/ATE497781T1/de not_active IP Right Cessation
- 2003-05-15 DK DK03730424T patent/DK1506009T3/da active
- 2003-05-15 AT AT03730424T patent/ATE395080T1/de active
- 2003-05-15 EP EP03730424A patent/EP1506009B1/en not_active Expired - Lifetime
- 2003-05-15 EP EP07075796A patent/EP1891970B1/en not_active Expired - Lifetime
- 2003-05-15 ES ES03730424T patent/ES2306871T3/es not_active Expired - Lifetime
- 2003-05-15 US US10/514,483 patent/US20050208079A1/en not_active Abandoned
- 2003-05-15 CA CA2830619A patent/CA2830619A1/en not_active Abandoned
- 2003-05-15 WO PCT/IB2003/002460 patent/WO2003097091A2/en not_active Ceased
- 2003-05-15 DE DE60336027T patent/DE60336027D1/de not_active Expired - Lifetime
- 2003-05-15 CA CA2485847A patent/CA2485847C/en not_active Expired - Fee Related
- 2003-05-15 PT PT03730424T patent/PT1506009E/pt unknown
- 2003-05-15 DE DE60320979T patent/DE60320979D1/de not_active Expired - Lifetime
- 2003-05-15 SI SI200331275T patent/SI1506009T1/sl unknown
- 2003-05-15 AU AU2003241104A patent/AU2003241104A1/en not_active Abandoned
- 2003-05-15 JP JP2004505087A patent/JP5110767B2/ja not_active Expired - Fee Related
-
2007
- 2007-02-01 US US11/701,250 patent/US7824688B2/en not_active Expired - Fee Related
-
2008
- 2008-07-31 CY CY20081100809T patent/CY1108234T1/el unknown
-
2009
- 2009-12-25 JP JP2009294467A patent/JP2010131017A/ja active Pending
-
2010
- 2010-08-11 US US12/854,248 patent/US8398990B2/en not_active Expired - Fee Related
-
2012
- 2012-07-27 JP JP2012166700A patent/JP5684758B2/ja not_active Expired - Fee Related
-
2013
- 2013-02-26 US US13/777,903 patent/US8679506B2/en not_active Expired - Fee Related
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