JP2012210156A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012210156A5 JP2012210156A5 JP2011076235A JP2011076235A JP2012210156A5 JP 2012210156 A5 JP2012210156 A5 JP 2012210156A5 JP 2011076235 A JP2011076235 A JP 2011076235A JP 2011076235 A JP2011076235 A JP 2011076235A JP 2012210156 A5 JP2012210156 A5 JP 2012210156A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- mixed
- flk
- cardiomyocytes
- kdr positive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000004027 cell Anatomy 0.000 claims 17
- 238000000034 method Methods 0.000 claims 13
- 210000004413 cardiac myocyte Anatomy 0.000 claims 6
- 238000012258 culturing Methods 0.000 claims 4
- 210000002889 endothelial cell Anatomy 0.000 claims 4
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 2
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 2
- 230000002107 myocardial effect Effects 0.000 claims 2
- 229930105110 Cyclosporin A Natural products 0.000 claims 1
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 claims 1
- 108010036949 Cyclosporine Proteins 0.000 claims 1
- 108010010803 Gelatin Proteins 0.000 claims 1
- 229960001265 ciclosporin Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229920000159 gelatin Polymers 0.000 claims 1
- 239000008273 gelatin Substances 0.000 claims 1
- 235000019322 gelatine Nutrition 0.000 claims 1
- 235000011852 gelatine desserts Nutrition 0.000 claims 1
- 208000019622 heart disease Diseases 0.000 claims 1
- 238000010030 laminating Methods 0.000 claims 1
- 238000003475 lamination Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
- DMRMZQATXPQOTP-GWTDSMLYSA-M sodium;(4ar,6r,7r,7as)-6-(6-amino-8-bromopurin-9-yl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4h-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol Chemical compound [Na+].C([C@H]1O2)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=CN=C2N)=C2N=C1Br DMRMZQATXPQOTP-GWTDSMLYSA-M 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
- 229920000208 temperature-responsive polymer Polymers 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011076235A JP5840855B2 (ja) | 2011-03-30 | 2011-03-30 | 胚性幹細胞から心筋シートを製造する方法 |
| PCT/JP2012/059427 WO2012133945A1 (ja) | 2011-03-30 | 2012-03-30 | 胚性幹細胞から心筋シートを製造する方法 |
| EP12763936.7A EP2692859B1 (en) | 2011-03-30 | 2012-03-30 | Method for producing cardiomyocyte sheet from embryonic stem cells |
| US14/009,018 US9623052B2 (en) | 2011-03-30 | 2012-03-30 | Method for producing myocardial sheet from embryonic stem cell |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011076235A JP5840855B2 (ja) | 2011-03-30 | 2011-03-30 | 胚性幹細胞から心筋シートを製造する方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012210156A JP2012210156A (ja) | 2012-11-01 |
| JP2012210156A5 true JP2012210156A5 (OSRAM) | 2014-05-15 |
| JP5840855B2 JP5840855B2 (ja) | 2016-01-06 |
Family
ID=46931617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011076235A Expired - Fee Related JP5840855B2 (ja) | 2011-03-30 | 2011-03-30 | 胚性幹細胞から心筋シートを製造する方法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9623052B2 (OSRAM) |
| EP (1) | EP2692859B1 (OSRAM) |
| JP (1) | JP5840855B2 (OSRAM) |
| WO (1) | WO2012133945A1 (OSRAM) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010044417A1 (ja) | 2008-10-14 | 2010-04-22 | 株式会社セルシード | 温度応答性細胞培養器材、及びその製造方法 |
| EP2826855B1 (en) * | 2012-03-15 | 2018-08-29 | iHeart Japan Corporation | Myocardial sheet |
| CN105247041B (zh) * | 2013-05-31 | 2018-04-20 | 爱心细胞有限公司 | 组入有水凝胶的层叠细胞膜片 |
| JP6248617B2 (ja) * | 2013-12-25 | 2017-12-20 | 大日本印刷株式会社 | 細胞シートの製造方法 |
| WO2015166638A1 (ja) * | 2014-05-01 | 2015-11-05 | ｉＨｅａｒｔ Ｊａｐａｎ株式会社 | Ｃｄ８２陽性心筋前駆細胞 |
| EP3219790B1 (en) | 2014-11-12 | 2021-08-04 | Terumo Kabushiki Kaisha | Myocardial cell sheet |
| WO2017038562A1 (ja) * | 2015-08-31 | 2017-03-09 | 学校法人東京女子医科大学 | 多能性幹細胞を減少させる方法、多能性幹細胞を減少させた細胞集団の製造方法 |
| CN109996866A (zh) | 2016-12-02 | 2019-07-09 | 宝生物工程株式会社 | 用于产生内皮细胞的方法 |
| US11401264B2 (en) | 2018-03-30 | 2022-08-02 | Orizuru Therapeutics, Inc. | Heterocyclic compound |
| WO2019189554A1 (ja) | 2018-03-30 | 2019-10-03 | 国立大学法人京都大学 | 心筋細胞成熟促進剤 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| WO2002008387A1 (en) | 2000-07-21 | 2002-01-31 | Cellseed Inc. | Heart muscle-like cell sheet, three-dimensional construct, heart muscle-like tissue and process for producing the same |
| EP1659979B1 (en) | 2003-08-01 | 2015-04-01 | Cellseed Inc. | Three-dimentional tissue structure |
| BRPI0414961A (pt) | 2003-10-03 | 2006-11-07 | Keiichi Fukuda | processo de indução da diferenciação de células tronco em células do miocárdio |
| CA2577201C (en) | 2004-08-27 | 2016-02-09 | Daiichi Asubio Pharma Co., Ltd. | A method of selecting a cardiomyocyte using intracellular mitochondria as an indicator |
| KR20130099253A (ko) | 2005-06-22 | 2013-09-05 | 제론 코포레이션 | 영장류 다능성 줄기 세포의 심근세포 계통 세포로의 분화 |
| KR101348325B1 (ko) | 2006-01-31 | 2014-01-08 | 각고호우징 게이오기주크 | 줄기세포 및 태아에서 유래된 심근세포 및 예정 심근세포의제조방법 |
| WO2007126077A1 (ja) | 2006-04-28 | 2007-11-08 | Asubio Pharma Co., Ltd. | 多能性幹細胞から心筋細胞を分化誘導する方法 |
| WO2009118928A1 (en) * | 2008-03-26 | 2009-10-01 | Kyoto University | Efficient production and use of highly cardiogenic progenitors and cardiomyocytes from embryonic and induced pluripotent stem cells |
| JP5387294B2 (ja) | 2009-09-29 | 2014-01-15 | ブラザー工業株式会社 | サーバに接続されるプリンタ及びサーバ |
| JP5654786B2 (ja) | 2010-06-28 | 2015-01-14 | 株式会社セルシード | アクリルアミド誘導体および該誘導体を含む重合体 |
-
2011
- 2011-03-30 JP JP2011076235A patent/JP5840855B2/ja not_active Expired - Fee Related
-
2012
- 2012-03-30 WO PCT/JP2012/059427 patent/WO2012133945A1/ja not_active Ceased
- 2012-03-30 US US14/009,018 patent/US9623052B2/en not_active Expired - Fee Related
- 2012-03-30 EP EP12763936.7A patent/EP2692859B1/en not_active Not-in-force
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012210156A5 (OSRAM) | ||
| Yuan et al. | A strategy for depositing different types of cells in three dimensions to mimic tubular structures in tissues. | |
| JP2012105678A5 (OSRAM) | ||
| JP2014533491A5 (OSRAM) | ||
| JP2016539641A5 (OSRAM) | ||
| EP4450615A3 (en) | Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy | |
| IL212387A0 (en) | Perfusion bioreactors, cell culture systems, and methods for production of cells and cell-derived products | |
| JP2011525793A5 (OSRAM) | ||
| JP2018508198A5 (OSRAM) | ||
| EP4289944A3 (en) | Method for preparing genetically-modified t cells which express chimeric antigen receptor | |
| JP2012519584A5 (OSRAM) | ||
| WO2012168930A3 (en) | Culture media for stem cells | |
| JP2011225577A5 (OSRAM) | ||
| BR112015019950A2 (pt) | Método para gerar linhagem de células-tronco embrionárias (es) de rato, e, cultura in vitro | |
| JP2009535025A5 (OSRAM) | ||
| WO2015188106A3 (en) | Perfusion culturing methods and uses thereof | |
| JP2015165823A5 (OSRAM) | ||
| JP2016501013A5 (OSRAM) | ||
| WO2016030489A3 (en) | A process for the production of adenovirus | |
| JP2013510570A5 (OSRAM) | ||
| JP2015159895A5 (OSRAM) | ||
| HK1203083A1 (en) | Enzyme cocktails prepared from mixed cultures | |
| AU2012295913A8 (en) | Production method for nucleic acid aptamer | |
| WO2010020876A3 (en) | Cell culture method to form aggregates | |
| JP2017511146A5 (OSRAM) |