JP2012162557A5 - - Google Patents
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- JP2012162557A5 JP2012162557A5 JP2012090664A JP2012090664A JP2012162557A5 JP 2012162557 A5 JP2012162557 A5 JP 2012162557A5 JP 2012090664 A JP2012090664 A JP 2012090664A JP 2012090664 A JP2012090664 A JP 2012090664A JP 2012162557 A5 JP2012162557 A5 JP 2012162557A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- weight
- composition according
- skin penetration
- physiologically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 210000003491 skin Anatomy 0.000 claims 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 6
- 239000013543 active substance Substances 0.000 claims 6
- 239000002904 solvent Substances 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 5
- 239000003961 penetration enhancing agent Substances 0.000 claims 5
- 239000000126 substance Substances 0.000 claims 5
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 4
- 230000035515 penetration Effects 0.000 claims 4
- 238000007789 sealing Methods 0.000 claims 4
- 238000001704 evaporation Methods 0.000 claims 3
- PJMPHNIQZUBGLI-UHFFFAOYSA-N fentanyl Chemical compound C=1C=CC=CC=1N(C(=O)CC)C(CC1)CCN1CCC1=CC=CC=C1 PJMPHNIQZUBGLI-UHFFFAOYSA-N 0.000 claims 3
- 229960002428 fentanyl Drugs 0.000 claims 3
- 229960003921 octisalate Drugs 0.000 claims 3
- WCJLCOAEJIHPCW-UHFFFAOYSA-N octyl 2-hydroxybenzoate Chemical compound CCCCCCCCOC(=O)C1=CC=CC=C1O WCJLCOAEJIHPCW-UHFFFAOYSA-N 0.000 claims 3
- 239000002244 precipitate Substances 0.000 claims 3
- 230000001737 promoting effect Effects 0.000 claims 3
- WYWZRNAHINYAEF-AWEZNQCLSA-N [(2s)-2-ethylhexyl] 4-(dimethylamino)benzoate Chemical compound CCCC[C@H](CC)COC(=O)C1=CC=C(N(C)C)C=C1 WYWZRNAHINYAEF-AWEZNQCLSA-N 0.000 claims 2
- 239000000443 aerosol Substances 0.000 claims 2
- 230000000975 bioactive effect Effects 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000003623 enhancer Substances 0.000 claims 2
- 229960002638 padimate o Drugs 0.000 claims 2
- 239000007921 spray Substances 0.000 claims 2
- 238000010521 absorption reaction Methods 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000000339 bright-field microscopy Methods 0.000 claims 1
- 238000000113 differential scanning calorimetry Methods 0.000 claims 1
- 210000002615 epidermis Anatomy 0.000 claims 1
- 230000008020 evaporation Effects 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 210000000434 stratum corneum Anatomy 0.000 claims 1
- 230000037317 transdermal delivery Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39108102P | 2002-06-25 | 2002-06-25 | |
| US60/391,081 | 2002-06-25 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004514440A Division JP5160018B2 (ja) | 2002-06-25 | 2003-06-24 | 非晶質医薬組成物を用いる経皮送達速度調節 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012162557A JP2012162557A (ja) | 2012-08-30 |
| JP2012162557A5 true JP2012162557A5 (https=) | 2012-12-06 |
| JP5568108B2 JP5568108B2 (ja) | 2014-08-06 |
Family
ID=30000668
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004514440A Expired - Fee Related JP5160018B2 (ja) | 2002-06-25 | 2003-06-24 | 非晶質医薬組成物を用いる経皮送達速度調節 |
| JP2012090664A Expired - Fee Related JP5568108B2 (ja) | 2002-06-25 | 2012-04-12 | 非晶質医薬組成物を用いる経皮送達速度調節 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004514440A Expired - Fee Related JP5160018B2 (ja) | 2002-06-25 | 2003-06-24 | 非晶質医薬組成物を用いる経皮送達速度調節 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US8357393B2 (https=) |
| EP (2) | EP1534235B1 (https=) |
| JP (2) | JP5160018B2 (https=) |
| KR (2) | KR20050045946A (https=) |
| AU (1) | AU2003240301B2 (https=) |
| BR (1) | BRPI0312007B1 (https=) |
| CA (1) | CA2489865C (https=) |
| EA (1) | EA009024B1 (https=) |
| ES (1) | ES2589077T3 (https=) |
| NZ (1) | NZ537360A (https=) |
| WO (1) | WO2004000263A1 (https=) |
Families Citing this family (41)
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| JP5913614B2 (ja) | 2011-11-09 | 2016-04-27 | テイコク ファーマ ユーエスエー インコーポレーテッド | 皮膚新生物の処置方法 |
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| US8785426B1 (en) | 2013-12-13 | 2014-07-22 | Upsher-Smith Laboratories, Inc. | Testosterone gel compositions and related methods |
| MX2017012062A (es) | 2015-03-23 | 2018-06-18 | Biopharmx Inc | Composicion farmaceutica de tetraciclina para uso dermatologico. |
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| US11523994B2 (en) | 2018-01-10 | 2022-12-13 | Celista Pharmaceuticals Llc | Testosterone transdermal spray with film |
| AU2019299538B2 (en) * | 2018-07-05 | 2025-05-08 | Celista Pharmaceuticals Llc | Testosterone and estradiol transdermal spray |
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| FR2851470B1 (fr) | 2003-02-20 | 2007-11-16 | Besins Int Belgique | Composition pharmaceutique pour administration transdermique ou transmuqueuse |
| CA2433101A1 (en) | 2003-06-23 | 2004-12-23 | Igor Gonda | Method of treatment of a female suffering from androgen insufficiency |
| US20050025833A1 (en) | 2003-07-16 | 2005-02-03 | Chaim Aschkenasy | Pharmaceutical composition and method for transdermal drug delivery |
| US20050020552A1 (en) | 2003-07-16 | 2005-01-27 | Chaim Aschkenasy | Pharmaceutical composition and method for transdermal drug delivery |
| US20050042268A1 (en) | 2003-07-16 | 2005-02-24 | Chaim Aschkenasy | Pharmaceutical composition and method for transdermal drug delivery |
| DK1670433T3 (da) | 2003-10-10 | 2012-03-12 | Ferring Bv | Transdermal farmaceutisk formulering til mindskelse af hudrester |
| JP2007511544A (ja) | 2003-11-19 | 2007-05-10 | アクルックス・ディ・ディ・エス・プロプライエタリー・リミテッド | アミロイド症の予防若しくは治療のための組成物および方法 |
| US20050123575A1 (en) | 2003-12-03 | 2005-06-09 | Eilon Asculai | Spreadable compositions for topical use, an improved process of making same and methods of using same |
| CN1946431B (zh) | 2004-03-03 | 2011-12-07 | 雷文斯治疗公司 | 用于肉毒毒素的局部施用和透皮递送的组合物和方法 |
| EP1634583A1 (en) | 2004-09-09 | 2006-03-15 | Laboratoires Besins International | Testosterone gels comprising propylene glycol as penetration enhancer |
| ZA200711040B (en) | 2005-06-03 | 2009-04-29 | Acrux Dds Pty Ltd | Method and composition for transdermal drug delivery |
-
2003
- 2003-06-24 KR KR1020047021362A patent/KR20050045946A/ko not_active Ceased
- 2003-06-24 EP EP03729716.5A patent/EP1534235B1/en not_active Revoked
- 2003-06-24 EA EA200500084A patent/EA009024B1/ru not_active IP Right Cessation
- 2003-06-24 JP JP2004514440A patent/JP5160018B2/ja not_active Expired - Fee Related
- 2003-06-24 EP EP10010704A patent/EP2266533A3/en not_active Withdrawn
- 2003-06-24 ES ES03729716.5T patent/ES2589077T3/es not_active Expired - Lifetime
- 2003-06-24 KR KR1020107009520A patent/KR20100055542A/ko not_active Ceased
- 2003-06-24 WO PCT/AU2003/000787 patent/WO2004000263A1/en not_active Ceased
- 2003-06-24 CA CA2489865A patent/CA2489865C/en not_active Expired - Fee Related
- 2003-06-24 NZ NZ537360A patent/NZ537360A/en not_active IP Right Cessation
- 2003-06-24 AU AU2003240301A patent/AU2003240301B2/en not_active Ceased
- 2003-06-24 BR BRPI0312007-4A patent/BRPI0312007B1/pt not_active IP Right Cessation
-
2004
- 2004-12-07 US US11/004,926 patent/US8357393B2/en not_active Expired - Fee Related
-
2009
- 2009-12-18 US US12/642,301 patent/US20100166674A1/en not_active Abandoned
-
2012
- 2012-04-12 JP JP2012090664A patent/JP5568108B2/ja not_active Expired - Fee Related
- 2012-12-11 US US13/710,761 patent/US8784878B2/en not_active Expired - Fee Related
-
2014
- 2014-06-16 US US14/305,529 patent/US20150094290A1/en not_active Abandoned
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