JP2012082195A5 - - Google Patents
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- Publication number
- JP2012082195A5 JP2012082195A5 JP2011222079A JP2011222079A JP2012082195A5 JP 2012082195 A5 JP2012082195 A5 JP 2012082195A5 JP 2011222079 A JP2011222079 A JP 2011222079A JP 2011222079 A JP2011222079 A JP 2011222079A JP 2012082195 A5 JP2012082195 A5 JP 2012082195A5
- Authority
- JP
- Japan
- Prior art keywords
- dosage form
- drug
- hours
- administration
- plasma concentration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000002552 dosage form Substances 0.000 claims 83
- 229940079593 drug Drugs 0.000 claims 64
- 239000003814 drug Substances 0.000 claims 64
- 230000036470 plasma concentration Effects 0.000 claims 30
- DUGOZIWVEXMGBE-UHFFFAOYSA-N Methylphenidate Chemical compound C=1C=CC=CC=1C(C(=O)OC)C1CCCCN1 DUGOZIWVEXMGBE-UHFFFAOYSA-N 0.000 claims 17
- 229960001344 methylphenidate Drugs 0.000 claims 17
- 239000012729 immediate-release (IR) formulation Substances 0.000 claims 15
- 239000012530 fluid Substances 0.000 claims 11
- KWTSXDURSIMDCE-QMMMGPOBSA-N (S)-amphetamine Chemical compound C[C@H](N)CC1=CC=CC=C1 KWTSXDURSIMDCE-QMMMGPOBSA-N 0.000 claims 10
- 230000003204 osmotic effect Effects 0.000 claims 10
- 239000003826 tablet Substances 0.000 claims 10
- 239000002269 analeptic agent Substances 0.000 claims 9
- 239000012528 membrane Substances 0.000 claims 9
- 239000011248 coating agent Substances 0.000 claims 7
- 238000000576 coating method Methods 0.000 claims 7
- 210000003169 central nervous system Anatomy 0.000 claims 6
- 239000007891 compressed tablet Substances 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 6
- 229940025084 amphetamine Drugs 0.000 claims 5
- DUGOZIWVEXMGBE-CHWSQXEVSA-N dexmethylphenidate Chemical compound C([C@@H]1[C@H](C(=O)OC)C=2C=CC=CC=2)CCCN1 DUGOZIWVEXMGBE-CHWSQXEVSA-N 0.000 claims 5
- 229960001042 dexmethylphenidate Drugs 0.000 claims 5
- 229960001252 methamphetamine Drugs 0.000 claims 5
- MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 claims 5
- FRCFWPVMFJMNDP-UHFFFAOYSA-N n-propan-2-ylaniline Chemical compound CC(C)NC1=CC=CC=C1 FRCFWPVMFJMNDP-UHFFFAOYSA-N 0.000 claims 5
- 229960000761 pemoline Drugs 0.000 claims 5
- NRNCYVBFPDDJNE-UHFFFAOYSA-N pemoline Chemical compound O1C(N)=NC(=O)C1C1=CC=CC=C1 NRNCYVBFPDDJNE-UHFFFAOYSA-N 0.000 claims 5
- 230000001681 protective effect Effects 0.000 claims 4
- 239000000556 agonist Substances 0.000 claims 3
- 229940000041 nervous system drug Drugs 0.000 claims 3
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 238000006731 degradation reaction Methods 0.000 claims 2
- 230000003111 delayed effect Effects 0.000 claims 2
- 229960000632 dexamfetamine Drugs 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims 1
- GOOHAUXETOMSMM-UHFFFAOYSA-N Propylene oxide Chemical compound CC1CO1 GOOHAUXETOMSMM-UHFFFAOYSA-N 0.000 claims 1
- 229920002301 cellulose acetate Polymers 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- JUMYIBMBTDDLNG-OJERSXHUSA-N hydron;methyl (2r)-2-phenyl-2-[(2r)-piperidin-2-yl]acetate;chloride Chemical compound Cl.C([C@@H]1[C@H](C(=O)OC)C=2C=CC=CC=2)CCCN1 JUMYIBMBTDDLNG-OJERSXHUSA-N 0.000 claims 1
- 229960001033 methylphenidate hydrochloride Drugs 0.000 claims 1
- 239000006186 oral dosage form Substances 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8778798P | 1998-06-03 | 1998-06-03 | |
| US60/087,787 | 1998-06-03 | ||
| US09/253,317 | 1999-02-19 | ||
| US09/253,317 US6919373B1 (en) | 1996-11-12 | 1999-02-19 | Methods and devices for providing prolonged drug therapy |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000551752A Division JP2002516848A (ja) | 1998-06-03 | 1999-05-27 | 長時間の薬物療法を与える方法および装置 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014232011A Division JP2015028095A (ja) | 1998-06-03 | 2014-11-14 | 長時間の薬物療法を与える方法および装置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012082195A JP2012082195A (ja) | 2012-04-26 |
| JP2012082195A5 true JP2012082195A5 (enExample) | 2012-09-27 |
Family
ID=27733446
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011222079A Withdrawn JP2012082195A (ja) | 1998-06-03 | 2011-10-06 | 長時間の薬物療法を与える方法および装置 |
| JP2014232011A Pending JP2015028095A (ja) | 1998-06-03 | 2014-11-14 | 長時間の薬物療法を与える方法および装置 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014232011A Pending JP2015028095A (ja) | 1998-06-03 | 2014-11-14 | 長時間の薬物療法を与える方法および装置 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US7521067B1 (enExample) |
| JP (2) | JP2012082195A (enExample) |
| KR (1) | KR100827254B1 (enExample) |
| IL (3) | IL140020A (enExample) |
| NO (2) | NO333360B1 (enExample) |
| ZA (1) | ZA200007111B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100827254B1 (ko) | 1998-06-03 | 2008-05-07 | 알자 코포레이션 | 연장된 약물 치료를 제공하기 위한 방법 및 장치 |
| US20050232995A1 (en) | 2002-07-29 | 2005-10-20 | Yam Nyomi V | Methods and dosage forms for controlled delivery of paliperidone and risperidone |
| ES2909803T3 (es) | 2018-03-05 | 2022-05-10 | Amneal Complex Products Res Llc | Composiciones farmacéuticas programables para la cronoliberación de fármacos |
| CN111989093A (zh) * | 2018-04-16 | 2020-11-24 | S&R制药股份有限公司 | 一种用于治疗女性生育的负载在金属氢氧化物上的白藜芦醇与非负载纯白藜芦醇的混合物 |
| EP3970701B1 (en) | 2018-06-27 | 2025-05-07 | Amneal Complex Products Research LLC | Self-regulating osmotic gastroretentive drug delivery systems |
| AU2020212036B2 (en) * | 2019-01-25 | 2025-08-28 | Ironshore Pharmaceuticals & Development, Inc. | Methylphenidate compositions for treatment of attention deficit hyperactivity disorder |
| WO2020181127A1 (en) * | 2019-03-05 | 2020-09-10 | Kashiv Biosciences, Llc | Delayed release methylphenidate compositions |
| WO2020257250A1 (en) * | 2019-06-21 | 2020-12-24 | Kashiv Biosciences, Llc | Gastroretentive dosage forms of levodopa and carbidopa |
| US11964048B2 (en) | 2020-12-18 | 2024-04-23 | Amneal Complex Products Research Llc | Sustained release compositions comprising liothyronine |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB952006A (en) | 1962-02-21 | 1964-03-11 | John Holroyd & Company Ltd | Multi-layer tablet making machines |
| US3634584A (en) | 1969-02-13 | 1972-01-11 | American Home Prod | Sustained action dosage form |
| US4096238A (en) | 1974-12-23 | 1978-06-20 | Alza Corporation | Method for administering drug to the gastrointestinal tract |
| US4327725A (en) | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
| US4591500A (en) | 1983-04-25 | 1986-05-27 | Microencapsulation S.A. | Tablet having the shape of a capsule, process and device for its preparation |
| US4612008A (en) | 1983-05-11 | 1986-09-16 | Alza Corporation | Osmotic device with dual thermodynamic activity |
| US4783337A (en) | 1983-05-11 | 1988-11-08 | Alza Corporation | Osmotic system comprising plurality of members for dispensing drug |
| US4765989A (en) | 1983-05-11 | 1988-08-23 | Alza Corporation | Osmotic device for administering certain drugs |
| US4847093A (en) | 1986-06-19 | 1989-07-11 | Alza Corporation | Dosage form with means for governing rate of gas formation |
| US4874388A (en) | 1987-06-25 | 1989-10-17 | Alza Corporation | Multi-layer delivery system |
| US5236689A (en) | 1987-06-25 | 1993-08-17 | Alza Corporation | Multi-unit delivery system |
| US5391381A (en) | 1987-06-25 | 1995-02-21 | Alza Corporation | Dispenser capable of delivering plurality of drug units |
| US4915953A (en) | 1987-09-03 | 1990-04-10 | Alza Corporation | Dosage form for delivering acetaminophen or phenylpropanolamine |
| JP2770243B2 (ja) | 1989-09-21 | 1998-06-25 | ライオンエンジニアリング株式会社 | 錠剤成分量検査方法およびその装置 |
| US5213738A (en) | 1990-05-15 | 1993-05-25 | L. Perrigo Company | Method for making a capsule-shaped tablet |
| US5089270A (en) | 1990-05-15 | 1992-02-18 | L. Perrigo Company | Capsule-shaped tablet |
| US5464631A (en) | 1990-06-27 | 1995-11-07 | Warner-Lambert Company | Encapsulated dosage forms |
| US5156850A (en) * | 1990-08-31 | 1992-10-20 | Alza Corporation | Dosage form for time-varying patterns of drug delivery |
| US5190765A (en) | 1991-06-27 | 1993-03-02 | Alza Corporation | Therapy delayed |
| US5160744A (en) | 1991-06-27 | 1992-11-03 | Alza Corporation | Verapmil therapy |
| US5294770A (en) * | 1992-01-14 | 1994-03-15 | Alza Corporation | Laser tablet treatment system with dual access to tablet |
| US5248310A (en) * | 1992-03-27 | 1993-09-28 | Alza Corporation | Oral osmotic device with hydrogel driving member |
| US5422831A (en) | 1992-08-03 | 1995-06-06 | Iowa State University Research Foundation, Inc. | Acoustic and video imaging system for quality determination of pharmaceutical products |
| DE4417015A1 (de) | 1994-05-14 | 1995-11-16 | Maschimpex Gmbh | Sortierautomat zur Sortierung bzw. Klassifikation von Kleinprodukten der pharmazeutischen und der Süßwarenindustrie nach Form und Farbe |
| US5582838A (en) * | 1994-12-22 | 1996-12-10 | Merck & Co., Inc. | Controlled release drug suspension delivery device |
| US5558879A (en) * | 1995-04-28 | 1996-09-24 | Andrx Pharmaceuticals, Inc. | Controlled release formulation for water soluble drugs in which a passageway is formed in situ |
| ZA97976B (en) * | 1996-04-05 | 1997-08-18 | Alza Corp | Uniform drug delivery theraphy. |
| CN101518517B (zh) * | 1996-08-16 | 2014-11-26 | 阿尔萨公司 | 药物剂量逐渐增加的剂型 |
| US5824338A (en) | 1996-08-19 | 1998-10-20 | L. Perrigo Company | Caplet and gelatin covering therefor |
| DK0932388T5 (da) * | 1996-09-30 | 2011-06-27 | Alza Corp | Doseringsform og fremgangsmåde til indgivelse af lægemidler |
| DK0946151T3 (da) | 1996-11-25 | 2006-08-28 | Alza Corp | Doseringsform med stigende dosisfrigivelse |
| CN1158071C (zh) * | 1997-05-30 | 2004-07-21 | 渗透有限公司 | 多层渗透装置 |
| KR100827254B1 (ko) * | 1998-06-03 | 2008-05-07 | 알자 코포레이션 | 연장된 약물 치료를 제공하기 위한 방법 및 장치 |
-
1999
- 1999-05-27 KR KR1020007013610A patent/KR100827254B1/ko not_active Expired - Lifetime
- 1999-06-02 US US09/324,343 patent/US7521067B1/en not_active Expired - Fee Related
-
2000
- 2000-11-30 IL IL140020A patent/IL140020A/en not_active IP Right Cessation
- 2000-12-01 ZA ZA200007111A patent/ZA200007111B/xx unknown
-
2009
- 2009-03-11 US US12/402,075 patent/US8323691B2/en not_active Expired - Fee Related
-
2010
- 2010-07-27 NO NO20101070A patent/NO333360B1/no not_active IP Right Cessation
-
2011
- 2011-02-06 IL IL211081A patent/IL211081A0/en unknown
- 2011-10-06 JP JP2011222079A patent/JP2012082195A/ja not_active Withdrawn
-
2012
- 2012-10-15 IL IL222437A patent/IL222437A/en not_active IP Right Cessation
- 2012-10-18 US US13/654,958 patent/US8936810B2/en not_active Expired - Fee Related
-
2013
- 2013-03-06 NO NO20130342A patent/NO334409B1/no not_active IP Right Cessation
-
2014
- 2014-11-14 JP JP2014232011A patent/JP2015028095A/ja active Pending