JP2017530163A5 - - Google Patents
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- Publication number
- JP2017530163A5 JP2017530163A5 JP2017518197A JP2017518197A JP2017530163A5 JP 2017530163 A5 JP2017530163 A5 JP 2017530163A5 JP 2017518197 A JP2017518197 A JP 2017518197A JP 2017518197 A JP2017518197 A JP 2017518197A JP 2017530163 A5 JP2017530163 A5 JP 2017530163A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- chemokine receptor
- blocking antibody
- ccr9 inhibitor
- receptor ccr9
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 102100022718 Atypical chemokine receptor 2 Human genes 0.000 claims 19
- 239000003112 inhibitor Substances 0.000 claims 19
- 108010089833 chemokine receptor D6 Proteins 0.000 claims 18
- 230000000903 blocking effect Effects 0.000 claims 16
- 102000006495 integrins Human genes 0.000 claims 16
- 108010044426 integrins Proteins 0.000 claims 16
- 150000001875 compounds Chemical class 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 6
- 229960004914 vedolizumab Drugs 0.000 claims 6
- 208000022559 Inflammatory bowel disease Diseases 0.000 claims 5
- 241000124008 Mammalia Species 0.000 claims 4
- 229960000106 biosimilars Drugs 0.000 claims 3
- 206010009900 Colitis ulcerative Diseases 0.000 claims 2
- 208000011231 Crohn disease Diseases 0.000 claims 2
- 150000001204 N-oxides Chemical class 0.000 claims 2
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 2
- 102000019034 Chemokines Human genes 0.000 claims 1
- 108010012236 Chemokines Proteins 0.000 claims 1
- 101000678892 Homo sapiens Atypical chemokine receptor 2 Proteins 0.000 claims 1
- 101000716070 Homo sapiens C-C chemokine receptor type 9 Proteins 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462060454P | 2014-10-06 | 2014-10-06 | |
| US62/060,454 | 2014-10-06 | ||
| PCT/US2015/054077 WO2016057424A1 (en) | 2014-10-06 | 2015-10-05 | Combination therapy of inhibitors of c-c chemokine receptor type 9 (ccr9) and anti-alha4beta7 integrin blocking antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020082164A Division JP7025781B2 (ja) | 2014-10-06 | 2020-05-07 | ＣＣケモカイン受容体９（ＣＣＲ９）の阻害剤と抗α４β７インテグリン遮断抗体の併用療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017530163A JP2017530163A (ja) | 2017-10-12 |
| JP2017530163A5 true JP2017530163A5 (enExample) | 2019-02-07 |
| JP6954834B2 JP6954834B2 (ja) | 2021-10-27 |
Family
ID=55632011
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017518197A Active JP6954834B2 (ja) | 2014-10-06 | 2015-10-05 | ＣＣケモカイン受容体９（ＣＣＲ９）の阻害剤と抗α４β７インテグリン遮断抗体の併用療法 |
| JP2020082164A Active JP7025781B2 (ja) | 2014-10-06 | 2020-05-07 | ＣＣケモカイン受容体９（ＣＣＲ９）の阻害剤と抗α４β７インテグリン遮断抗体の併用療法 |
| JP2022016197A Pending JP2022051829A (ja) | 2014-10-06 | 2022-02-04 | ＣＣケモカイン受容体９（ＣＣＲ９）の阻害剤と抗α４β７インテグリン遮断抗体の併用療法 |
| JP2024066342A Pending JP2024094370A (ja) | 2014-10-06 | 2024-04-16 | ＣＣケモカイン受容体９（ＣＣＲ９）の阻害剤と抗α４β７インテグリン遮断抗体の併用療法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020082164A Active JP7025781B2 (ja) | 2014-10-06 | 2020-05-07 | ＣＣケモカイン受容体９（ＣＣＲ９）の阻害剤と抗α４β７インテグリン遮断抗体の併用療法 |
| JP2022016197A Pending JP2022051829A (ja) | 2014-10-06 | 2022-02-04 | ＣＣケモカイン受容体９（ＣＣＲ９）の阻害剤と抗α４β７インテグリン遮断抗体の併用療法 |
| JP2024066342A Pending JP2024094370A (ja) | 2014-10-06 | 2024-04-16 | ＣＣケモカイン受容体９（ＣＣＲ９）の阻害剤と抗α４β７インテグリン遮断抗体の併用療法 |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US10532051B2 (enExample) |
| EP (2) | EP3204424B1 (enExample) |
| JP (4) | JP6954834B2 (enExample) |
| KR (3) | KR20240033093A (enExample) |
| CN (1) | CN107001467A (enExample) |
| AU (1) | AU2015328396B2 (enExample) |
| CA (2) | CA2960876C (enExample) |
| ES (1) | ES2971041T3 (enExample) |
| IL (2) | IL292655B2 (enExample) |
| MA (1) | MA40592A (enExample) |
| MX (2) | MX2017004344A (enExample) |
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| KR102083693B1 (ko) * | 2012-02-29 | 2020-03-02 | 케모센트릭스, 인크. | Ccr9 길항제로써 피라졸-1-일 벤젠 술폰아미드 |
| IL292655B2 (en) * | 2014-10-06 | 2024-03-01 | Chemocentryx Inc | CCR9 chemokine receptor inhibitor for use in a method for treating or reducing the development of inflammatory bowel diseases |
| US20200093850A1 (en) | 2016-12-07 | 2020-03-26 | Stelic Institute & Co., Inc. | Pharmaceutical composition for treatment and prevention of chronic disease |
| US20210154292A1 (en) * | 2019-11-21 | 2021-05-27 | Chemocentryx, Inc. | Compositions and Methods for Treating CCR9-Mediated Diseases using CCR9 Inhibitor and Anti-TNF-Alpha Blocking Antibodies |
| US20230107927A1 (en) | 2020-02-28 | 2023-04-06 | First Wave Bio, Inc. | Methods of treating iatrogenic autoimmune colitis |
| CN115484944A (zh) * | 2020-03-31 | 2022-12-16 | 坎莫森特里克斯公司 | 使用ccr9抑制剂和抗il-23阻断抗体治疗炎症性肠病的组合物和方法 |
| CN114314701B (zh) * | 2021-11-30 | 2023-10-20 | 昆明贵研药业有限公司 | 一种三氯氨铂酸钾的制备方法及其在制备顺式-氨-水-铂配合物中的应用 |
| TW202504919A (zh) | 2023-05-30 | 2025-02-01 | 美商派拉岡醫療公司 | α4β7整合素抗體組合物及使用方法 |
| WO2025177214A1 (en) * | 2024-02-20 | 2025-08-28 | Takeda Pharmaceutical Company Limited | Therapeutic methods |
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