JP2015529225A5 - - Google Patents
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- JP2015529225A5 JP2015529225A5 JP2015531246A JP2015531246A JP2015529225A5 JP 2015529225 A5 JP2015529225 A5 JP 2015529225A5 JP 2015531246 A JP2015531246 A JP 2015531246A JP 2015531246 A JP2015531246 A JP 2015531246A JP 2015529225 A5 JP2015529225 A5 JP 2015529225A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261698379P | 2012-09-07 | 2012-09-07 | |
| US61/698,379 | 2012-09-07 | ||
| PCT/US2013/058557 WO2014039855A1 (en) | 2012-09-07 | 2013-09-06 | Combination therapy of a type ii anti-cd20 antibody with a selective bcl-2 inhibitor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018126675A Division JP6637119B2 (ja) | 2012-09-07 | 2018-07-03 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ−２インヒビターの併用療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015529225A JP2015529225A (ja) | 2015-10-05 |
| JP2015529225A5 true JP2015529225A5 (enExample) | 2016-10-27 |
| JP6408993B2 JP6408993B2 (ja) | 2018-10-17 |
Family
ID=49253396
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015531246A Active JP6408993B2 (ja) | 2012-09-07 | 2013-09-06 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ−２インヒビターの併用療法 |
| JP2018126675A Active JP6637119B2 (ja) | 2012-09-07 | 2018-07-03 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ−２インヒビターの併用療法 |
| JP2019227891A Pending JP2020063279A (ja) | 2012-09-07 | 2019-12-18 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ−２インヒビターの併用療法 |
| JP2022064357A Pending JP2022091996A (ja) | 2012-09-07 | 2022-04-08 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ－２インヒビターの併用療法 |
| JP2024063799A Pending JP2024095793A (ja) | 2012-09-07 | 2024-04-11 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ－２インヒビターの併用療法 |
| JP2025207849A Pending JP2026041827A (ja) | 2012-09-07 | 2025-11-28 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ－２インヒビターの併用療法 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018126675A Active JP6637119B2 (ja) | 2012-09-07 | 2018-07-03 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ−２インヒビターの併用療法 |
| JP2019227891A Pending JP2020063279A (ja) | 2012-09-07 | 2019-12-18 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ−２インヒビターの併用療法 |
| JP2022064357A Pending JP2022091996A (ja) | 2012-09-07 | 2022-04-08 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ－２インヒビターの併用療法 |
| JP2024063799A Pending JP2024095793A (ja) | 2012-09-07 | 2024-04-11 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ－２インヒビターの併用療法 |
| JP2025207849A Pending JP2026041827A (ja) | 2012-09-07 | 2025-11-28 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ－２インヒビターの併用療法 |
Country Status (11)
| Country | Link |
|---|---|
| US (14) | US9539251B2 (enExample) |
| EP (2) | EP2892557A1 (enExample) |
| JP (6) | JP6408993B2 (enExample) |
| KR (2) | KR20200110711A (enExample) |
| CN (3) | CN104768581A (enExample) |
| CA (1) | CA2884307A1 (enExample) |
| HK (1) | HK1212240A1 (enExample) |
| MX (1) | MX2015002947A (enExample) |
| NZ (1) | NZ630166A (enExample) |
| RU (1) | RU2648476C2 (enExample) |
| WO (1) | WO2014039855A1 (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2672640T3 (es) | 2003-11-05 | 2018-06-15 | Roche Glycart Ag | Moléculas de unión a antígeno con afinidad de unión a receptores Fc y función efectora incrementadas |
| NZ583367A (en) | 2007-07-16 | 2012-10-26 | Genentech Inc | Anti-cd79b antibodies and immunoconjugates and methods of use |
| CL2008002083A1 (es) | 2007-07-16 | 2008-11-21 | Genentech Inc | Anticuerpo humanizado anti-cd79b/igbeta/b29; inmunoconjugado; metodo in vitro para determinar presencia de cd79b, inhibir crecimiento de celula con cd79b, o para detectara celula b; metodo para elaborar dicho anticyerpo humanizado; acido nucleico; celula huesped; composicion; metodo de elaboracion de inmunoconjugado; uso medico |
| ES2643239T3 (es) | 2008-01-31 | 2017-11-21 | Genentech, Inc. | Anticuerpos anti-CD79b e inmunoconjugados y métodos de uso |
| US20220315555A1 (en) | 2009-05-26 | 2022-10-06 | Abbvie Inc. | Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases |
| CA3007787C (en) | 2010-06-03 | 2020-03-10 | Pharmacyclics Llc | The use of inhibitors of bruton's tyrosine kinase (btk) |
| CN103987711B (zh) | 2011-10-14 | 2016-08-24 | 艾伯维公司 | 作为用于治疗癌症和免疫性和自身免疫性疾病的凋亡诱导剂的8-氨基甲酰基-2-(2,3-二取代吡啶-6-基)-1,2,3,4-四氢异喹啉衍生物 |
| CA2879570A1 (en) | 2012-07-24 | 2014-01-30 | Pharmacyclics, Inc. | Mutations associated with resistance to inhibitors of bruton's tyrosine kinase (btk) |
| CN104768581A (zh) | 2012-09-07 | 2015-07-08 | 吉宁特有限公司 | II型抗CD20抗体与选择性Bcl-2抑制剂的组合治疗 |
| WO2014168975A1 (en) * | 2013-04-08 | 2014-10-16 | Pharmacyclics, Inc. | Ibrutinib combination therapy |
| MX2016007885A (es) * | 2013-12-17 | 2017-01-11 | Genentech Inc | Metodos de tratamiento de cancer usando antagonistas de union del eje de pd-1 y un anticuerpo anti-cd20. |
| ES2995052T3 (en) | 2014-04-23 | 2025-02-05 | Juno Therapeutics Inc | Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy |
| EP3179991B1 (en) * | 2014-08-11 | 2021-10-06 | Acerta Pharma B.V. | Therapeutic combinations of a btk inhibitor and a bcl-2 inhibitor |
| DK3262071T3 (da) | 2014-09-23 | 2020-06-15 | Hoffmann La Roche | Fremgangsmåde til anvendelse af anti-CD79b-immunkonjugater |
| TW201639573A (zh) * | 2015-02-03 | 2016-11-16 | 吉李德科學股份有限公司 | 有關治療癌症之合併治療 |
| WO2016207278A1 (en) * | 2015-06-23 | 2016-12-29 | Innate Pharma | Multispecific nk engager proteins |
| PE20221007A1 (es) | 2015-06-24 | 2022-06-15 | Hoffmann La Roche | Anticuerpos anti-receptor de transferrina con afinidad disenada |
| WO2017004091A1 (en) * | 2015-06-29 | 2017-01-05 | Genentech, Inc. | Type ii anti-cd20 antibody for use in organ transplantation |
| CA2990465A1 (en) * | 2015-07-07 | 2017-01-12 | Genentech, Inc. | Combination therapy with an anti-her2 antibody-drug conjugate and a bcl-2 inhibitor |
| US20180207164A1 (en) * | 2015-08-03 | 2018-07-26 | Gilead Sciences, Inc. | Combination therapies for treating cancers |
| WO2017055542A1 (en) | 2015-10-02 | 2017-04-06 | F. Hoffmann-La Roche Ag | Bispecific anti-human cd20/human transferrin receptor antibodies and methods of use |
| AR106189A1 (es) | 2015-10-02 | 2017-12-20 | Hoffmann La Roche | ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO |
| BR112018008882A8 (pt) | 2015-11-03 | 2019-02-26 | Univ Texas | método para tratar um distúrbio proliferativo e produto farmacêutico |
| CN107384932B (zh) * | 2016-08-31 | 2020-10-20 | 北京天广实生物技术股份有限公司 | 抗人cd20人源化单克隆抗体mil62、其制备方法及用途 |
| CA3046489A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| US20210138213A1 (en) | 2017-03-30 | 2021-05-13 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| JP7368856B2 (ja) | 2017-07-25 | 2023-10-25 | トゥルーバインディング，インコーポレイテッド | Ｔｉｍ－３とそのリガンドとの相互作用の遮断によるがん治療 |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| WO2019246317A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease or condition in a tissue originating from the endoderm |
| EP3672595B1 (en) | 2018-07-31 | 2021-07-21 | Ascentage Pharma (Suzhou) Co., Ltd. | Combination product of bcl-2 inhibitor and chemotherapeutic agent and use thereof in the prevention and/or treatment of diseases |
| CN110772640B (zh) * | 2018-07-31 | 2023-02-03 | 苏州亚盛药业有限公司 | Bcl-2抑制剂与利妥昔单抗和/或苯达莫司汀或与CHOP联合的协同抗肿瘤作用 |
| CA3112584A1 (en) | 2018-09-17 | 2020-03-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Bicistronic chimeric antigen receptors targeting cd19 and cd20 and their uses |
| KR20210070330A (ko) * | 2018-10-01 | 2021-06-14 | 아디셋 바이오, 인크. | 혈액 종양의 치료를 위한 조작된 및 비-조작된 γδ-T 세포에 관한 조성물 및 방법 |
| AU2019374142A1 (en) | 2018-11-01 | 2021-05-27 | Syros Pharmaceuticals, Inc. | Methods of treating cancer in biomarker-identified patients with non-covalent inhibitors of cyclin-dependent kinase 7 (CDK7) |
| CN116726361A (zh) | 2018-11-19 | 2023-09-12 | 比奥拉治疗股份有限公司 | 用生物治疗剂治疗疾病的方法和装置 |
| CN120058944A (zh) | 2019-01-30 | 2025-05-30 | 真和制药有限公司 | 抗gal3抗体及其用途 |
| BR112022007376A2 (pt) | 2019-10-21 | 2022-07-05 | Novartis Ag | Terapias de combinação com venetoclax e inibidores de tim-3 |
| AU2020370832A1 (en) | 2019-10-21 | 2022-05-19 | Novartis Ag | TIM-3 inhibitors and uses thereof |
| WO2021119482A1 (en) | 2019-12-13 | 2021-06-17 | Progenity, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
| JP2023528797A (ja) | 2020-05-26 | 2023-07-06 | トゥルーバインディング，インコーポレイテッド | ガレクチン－３を遮断することにより炎症性疾患を処置する方法 |
| MX2023005609A (es) | 2020-11-13 | 2023-05-29 | Novartis Ag | Terapias de combinacion con celulas que expresan receptores quimericos para el antigeno (car). |
| US20240165153A1 (en) | 2021-03-24 | 2024-05-23 | The United States Of America,As Represented By The Secretary,Department Of Health And Human Services | Bicistronic chimeric antigen receptors designed to reduce retroviral recombination and uses thereof |
| US20250319183A1 (en) | 2021-04-07 | 2025-10-16 | David Avigan | Compositions and methods for the treatment of cancer |
| JP2024515108A (ja) * | 2021-04-21 | 2024-04-04 | セルジーン コーポレーション | ２－（２，６－ジオキソピペリジン－３－イル）－４－（（２－フルオロ－４－（（３－モルホリノアゼチジン－１－イル）メチル）ベンジル）アミノ）イソインドリン－１，３－ジオンを使用して非ホジキンリンパ腫を治療する方法 |
| AU2021443318A1 (en) | 2021-04-30 | 2023-09-07 | F. Hoffmann-La Roche Ag | Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate |
| IL312692A (en) | 2021-11-16 | 2024-07-01 | Genentech Inc | Methods and compositions for the treatment of systemic lupus erythematosus (SLE) with musontuzumab |
| KR20250044423A (ko) * | 2022-08-09 | 2025-03-31 | 캉바이다 (시추안) 바이오테크놀로지 씨오. 엘티디. | 피페라진 화합물과 pd-1 억제제 또는 pd-l1 억제제의 조성물 및 종양 치료에 있어서의 그의 용도 |
| CN121127253A (zh) | 2023-02-28 | 2025-12-12 | 朱诺治疗学股份有限公司 | 治疗系统性自身免疫性疾病的细胞疗法 |
| TW202533828A (zh) * | 2024-02-22 | 2025-09-01 | 瑞典商阿斯特捷利康公司 | Ａｋｔ抑制劑、ｂｃｌ－２抑制劑、及抗ｃｄ２０抗體之治療組合 |
| US20260061053A1 (en) | 2024-08-28 | 2026-03-05 | Juno Therapeutics, Inc. | Cd19-directed chimeric antigen receptor cell therapy for treating autoimmune and neurological diseases |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US5204244A (en) | 1987-10-27 | 1993-04-20 | Oncogen | Production of chimeric antibodies by homologous recombination |
| US5202238A (en) | 1987-10-27 | 1993-04-13 | Oncogen | Production of chimeric antibodies by homologous recombination |
| ES2434961T5 (es) | 1998-04-20 | 2018-01-18 | Roche Glycart Ag | Ingeniería de glicosilación de anticuerpos para mejorar la citotoxicidad celular dependiente del anticuerpo |
| JP2002515511A (ja) | 1998-05-15 | 2002-05-28 | イムクローン システムズ インコーポレイティド | 放射線及び成長因子レセプター・チロシン・キナーゼのインヒビターを使用するヒト腫瘍の治療 |
| RU2321630C2 (ru) | 2001-08-03 | 2008-04-10 | Гликарт Биотекнолоджи АГ | Гликозилированные антитела (варианты), обладающие повышенной антителозависимой клеточной цитотоксичностью |
| CN102911987B (zh) | 2002-04-09 | 2015-09-30 | 协和发酵麒麟株式会社 | 基因组被修饰的细胞 |
| PL216630B1 (pl) | 2002-10-17 | 2014-04-30 | Genmab As | Izolowane ludzkie przeciwciało monoklonalne wiążące ludzki CD20, związane z tym przeciwciałem transfektoma, komórka gospodarza, transgeniczne zwierzę lub roślina, kompozycja, immunokoniugat, cząsteczka bispecyficzna, wektor ekspresyjny, kompozycja farmaceutyczna, zastosowanie medyczne, zestaw oraz przeciwciało antyidiotypowe i jego zastosowanie |
| ES2672640T3 (es) * | 2003-11-05 | 2018-06-15 | Roche Glycart Ag | Moléculas de unión a antígeno con afinidad de unión a receptores Fc y función efectora incrementadas |
| US7767684B2 (en) | 2003-11-13 | 2010-08-03 | Abbott Laboratories | Apoptosis promoters |
| EP2061560A2 (en) | 2006-09-05 | 2009-05-27 | Abbott Laboratories | Bcl inhibitors for treating platelet excess |
| US20090098118A1 (en) | 2007-10-15 | 2009-04-16 | Thomas Friess | Combination therapy of a type ii anti-cd20 antibody with an anti-bcl-2 active agent |
| US8546399B2 (en) | 2009-05-26 | 2013-10-01 | Abbvie Inc. | Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases |
| CN102448959B (zh) | 2009-05-26 | 2015-06-17 | 艾伯维巴哈马有限公司 | 用于治疗癌症和免疫和自身免疫疾病的细胞程序死亡诱导药剂 |
| WO2011100403A1 (en) * | 2010-02-10 | 2011-08-18 | Immunogen, Inc | Cd20 antibodies and uses thereof |
| TWI520960B (zh) * | 2010-05-26 | 2016-02-11 | 艾伯維有限公司 | 用於治療癌症及免疫及自體免疫疾病之細胞凋亡誘導劑 |
| CA2811805A1 (en) | 2010-10-29 | 2012-05-03 | Abbvie Inc. | Solid dispersions containing an apoptosis-inducing agent |
| UA113500C2 (xx) | 2010-10-29 | 2017-02-10 | Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб | |
| CN107266435A (zh) | 2010-11-23 | 2017-10-20 | Abbvie 公司 | 细胞凋亡诱导剂的盐和晶形 |
| SG190399A1 (en) | 2010-11-23 | 2013-06-28 | Abbvie Inc | Methods of treatment using selective bcl-2 inhibitors |
| CN104768581A (zh) | 2012-09-07 | 2015-07-08 | 吉宁特有限公司 | II型抗CD20抗体与选择性Bcl-2抑制剂的组合治疗 |
| AR095265A1 (es) | 2013-03-13 | 2015-09-30 | Abbvie Inc | Procesos para la preparación de un agente inductor de la apoptosis |
| MX389342B (es) | 2015-05-26 | 2025-03-20 | Hoffmann La Roche | Un anticuerpo anti-cd20 en combinación con un inhibidor de bcl-2 y un inhibidor de mdm2 para usarse en el tratamiento de cáncer. |
| BR112018008882A8 (pt) * | 2015-11-03 | 2019-02-26 | Univ Texas | método para tratar um distúrbio proliferativo e produto farmacêutico |
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2013
- 2013-09-06 CN CN201380057990.6A patent/CN104768581A/zh active Pending
- 2013-09-06 CN CN202010088179.6A patent/CN111437386A/zh active Pending
- 2013-09-06 HK HK16100331.0A patent/HK1212240A1/xx unknown
- 2013-09-06 NZ NZ630166A patent/NZ630166A/en unknown
- 2013-09-06 CN CN202010088180.9A patent/CN111481552A/zh active Pending
- 2013-09-06 CA CA2884307A patent/CA2884307A1/en active Pending
- 2013-09-06 JP JP2015531246A patent/JP6408993B2/ja active Active
- 2013-09-06 US US14/020,761 patent/US9539251B2/en active Active
- 2013-09-06 RU RU2015112576A patent/RU2648476C2/ru active
- 2013-09-06 MX MX2015002947A patent/MX2015002947A/es active IP Right Grant
- 2013-09-06 KR KR1020207026653A patent/KR20200110711A/ko active Pending
- 2013-09-06 WO PCT/US2013/058557 patent/WO2014039855A1/en not_active Ceased
- 2013-09-06 EP EP13767170.7A patent/EP2892557A1/en not_active Withdrawn
- 2013-09-06 EP EP21173041.1A patent/EP3919079A1/en active Pending
- 2013-09-06 KR KR1020157008862A patent/KR102158467B1/ko active Active
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2016
- 2016-11-30 US US15/365,595 patent/US11413282B2/en active Active
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2018
- 2018-07-03 JP JP2018126675A patent/JP6637119B2/ja active Active
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2019
- 2019-12-18 JP JP2019227891A patent/JP2020063279A/ja active Pending
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2020
- 2020-03-23 US US16/827,650 patent/US10993942B2/en active Active
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2021
- 2021-02-26 US US17/187,468 patent/US11110087B2/en active Active
- 2021-03-05 US US17/193,795 patent/US20220008413A1/en not_active Abandoned
- 2021-08-05 US US17/395,366 patent/US20220211696A1/en not_active Abandoned
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2022
- 2022-03-30 US US17/709,324 patent/US20220265642A1/en not_active Abandoned
- 2022-04-08 JP JP2022064357A patent/JP2022091996A/ja active Pending
- 2022-06-07 US US17/834,709 patent/US11590128B2/en active Active
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2023
- 2023-01-20 US US18/157,680 patent/US20230226045A1/en not_active Abandoned
- 2023-03-28 US US18/191,810 patent/US20230255959A1/en not_active Abandoned
- 2023-09-07 US US18/463,252 patent/US20240000776A1/en not_active Abandoned
- 2023-11-10 US US18/506,606 patent/US20240108616A1/en not_active Abandoned
- 2023-12-08 US US18/534,251 patent/US20240180901A1/en not_active Abandoned
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2024
- 2024-04-11 JP JP2024063799A patent/JP2024095793A/ja active Pending
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2025
- 2025-01-17 US US19/030,370 patent/US20250152582A1/en not_active Abandoned
- 2025-11-28 JP JP2025207849A patent/JP2026041827A/ja active Pending