JP2015529225A5 - - Google Patents
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- JP2015529225A5 JP2015529225A5 JP2015531246A JP2015531246A JP2015529225A5 JP 2015529225 A5 JP2015529225 A5 JP 2015529225A5 JP 2015531246 A JP2015531246 A JP 2015531246A JP 2015531246 A JP2015531246 A JP 2015531246A JP 2015529225 A5 JP2015529225 A5 JP 2015529225A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261698379P | 2012-09-07 | 2012-09-07 | |
| US61/698,379 | 2012-09-07 | ||
| PCT/US2013/058557 WO2014039855A1 (en) | 2012-09-07 | 2013-09-06 | Combination therapy of a type ii anti-cd20 antibody with a selective bcl-2 inhibitor |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018126675A Division JP6637119B2 (ja) | 2012-09-07 | 2018-07-03 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ−２インヒビターの併用療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015529225A JP2015529225A (ja) | 2015-10-05 |
| JP2015529225A5 true JP2015529225A5 (enExample) | 2016-10-27 |
| JP6408993B2 JP6408993B2 (ja) | 2018-10-17 |
Family
ID=49253396
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015531246A Active JP6408993B2 (ja) | 2012-09-07 | 2013-09-06 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ−２インヒビターの併用療法 |
| JP2018126675A Active JP6637119B2 (ja) | 2012-09-07 | 2018-07-03 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ−２インヒビターの併用療法 |
| JP2019227891A Pending JP2020063279A (ja) | 2012-09-07 | 2019-12-18 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ−２インヒビターの併用療法 |
| JP2022064357A Pending JP2022091996A (ja) | 2012-09-07 | 2022-04-08 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ－２インヒビターの併用療法 |
| JP2024063799A Pending JP2024095793A (ja) | 2012-09-07 | 2024-04-11 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ－２インヒビターの併用療法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018126675A Active JP6637119B2 (ja) | 2012-09-07 | 2018-07-03 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ−２インヒビターの併用療法 |
| JP2019227891A Pending JP2020063279A (ja) | 2012-09-07 | 2019-12-18 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ−２インヒビターの併用療法 |
| JP2022064357A Pending JP2022091996A (ja) | 2012-09-07 | 2022-04-08 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ－２インヒビターの併用療法 |
| JP2024063799A Pending JP2024095793A (ja) | 2012-09-07 | 2024-04-11 | タイプＩＩ抗ＣＤ２０抗体と選択的Ｂｃｌ－２インヒビターの併用療法 |
Country Status (11)
| Country | Link |
|---|---|
| US (14) | US9539251B2 (enExample) |
| EP (2) | EP3919079A1 (enExample) |
| JP (5) | JP6408993B2 (enExample) |
| KR (2) | KR102158467B1 (enExample) |
| CN (3) | CN104768581A (enExample) |
| CA (1) | CA2884307A1 (enExample) |
| HK (1) | HK1212240A1 (enExample) |
| MX (1) | MX2015002947A (enExample) |
| NZ (1) | NZ630166A (enExample) |
| RU (1) | RU2648476C2 (enExample) |
| WO (1) | WO2014039855A1 (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20100303T1 (hr) | 2003-11-05 | 2010-07-31 | Roche Glycart Ag | Cd20 antitijela s povećanim afinitetom vezivanja fc receptora i efektorskim djelovanjem |
| CL2008002083A1 (es) | 2007-07-16 | 2008-11-21 | Genentech Inc | Anticuerpo humanizado anti-cd79b/igbeta/b29; inmunoconjugado; metodo in vitro para determinar presencia de cd79b, inhibir crecimiento de celula con cd79b, o para detectara celula b; metodo para elaborar dicho anticyerpo humanizado; acido nucleico; celula huesped; composicion; metodo de elaboracion de inmunoconjugado; uso medico |
| SI2474557T1 (sl) | 2007-07-16 | 2014-12-31 | Genentech, Inc. | Protiteles proti CD79b in imunokonjugati in postopki za uporabo |
| RS54883B1 (sr) | 2008-01-31 | 2016-10-31 | Genentech Inc | Anti-cd79b antitela i imunokonjugati i metode upotrebe |
| US20220315555A1 (en) | 2009-05-26 | 2022-10-06 | Abbvie Inc. | Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases |
| NZ717373A (en) | 2010-06-03 | 2017-11-24 | Pharmacyclics Llc | The use of inhibitors of bruton’s tyrosine kinase (btk) |
| US8889675B2 (en) | 2011-10-14 | 2014-11-18 | Abbvie Inc. | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
| US10954567B2 (en) | 2012-07-24 | 2021-03-23 | Pharmacyclics Llc | Mutations associated with resistance to inhibitors of Bruton's Tyrosine Kinase (BTK) |
| CN104768581A (zh) | 2012-09-07 | 2015-07-08 | 吉宁特有限公司 | II型抗CD20抗体与选择性Bcl-2抑制剂的组合治疗 |
| EP2983670A4 (en) * | 2013-04-08 | 2017-03-08 | Pharmacyclics LLC | Ibrutinib combination therapy |
| EP3083690A1 (en) * | 2013-12-17 | 2016-10-26 | F.Hoffmann-La Roche Ag | Methods of treating cancer using pd-1 axis binding antagonists and an anti-cd20 antibody |
| PT4219687T (pt) | 2014-04-23 | 2024-10-02 | Juno Therapeutics Inc | Métodos para isolamento, cultura, e manipulação genetica de populações de células imunes para terapêutica adotiva |
| US20170231986A1 (en) * | 2014-08-11 | 2017-08-17 | Acerta Pharma B.V. | Therapeutic Combinations of a BTK Inhibitor, a PI3K Inhibitor, a JAK-2 Inhibitor, and/or a BCL-2 Inhibitor |
| RS60349B8 (sr) | 2014-09-23 | 2022-10-31 | Hoffmann La Roche | Postupak upotrebe anti-cd79b imunokonjugata |
| TW201639573A (zh) * | 2015-02-03 | 2016-11-16 | 吉李德科學股份有限公司 | 有關治療癌症之合併治療 |
| AU2016284871B2 (en) * | 2015-06-23 | 2022-09-29 | Innate Pharma | Multispecific NK engager proteins |
| UA127809C2 (uk) | 2015-06-24 | 2024-01-10 | Ф. Хоффманн-Ля Рош Аг | Антитіло до рецептора трансферину зі спеціально підібраною афінністю |
| US20170029520A1 (en) * | 2015-06-29 | 2017-02-02 | Genentech, Inc. | Compositions and methods for use in organ transplantation |
| HRP20191019T1 (hr) * | 2015-07-07 | 2019-09-06 | F. Hoffmann - La Roche Ag | Kombinacijska terapija konjugatom protutijela i lijeka anti-her2 i inhibitorom bcl-2 |
| HK1255939A1 (zh) * | 2015-08-03 | 2019-09-06 | Gilead Sciences, Inc. | 用於治疗癌症之组合疗法 |
| AR106189A1 (es) | 2015-10-02 | 2017-12-20 | Hoffmann La Roche | ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO |
| KR20250052494A (ko) | 2015-10-02 | 2025-04-18 | 에프. 호프만-라 로슈 아게 | 이중특이성 항-인간 cd20/인간 트랜스페린 수용체 항체 및 사용 방법 |
| AU2016349279A1 (en) | 2015-11-03 | 2018-05-10 | Board Of Regents, The University Of Texas System | Combination of Bcl-2 inhibitor and MEK inhibitor for the treatment of cancer |
| CN107384932B (zh) | 2016-08-31 | 2020-10-20 | 北京天广实生物技术股份有限公司 | 抗人cd20人源化单克隆抗体mil62、其制备方法及用途 |
| EP3551034A1 (en) | 2016-12-07 | 2019-10-16 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| EP3600416B1 (en) | 2017-03-30 | 2023-06-07 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| US12227567B2 (en) | 2017-07-25 | 2025-02-18 | Truebinding, Inc. | Treating cancer by blocking the interaction of TIM-3 and its ligand |
| WO2019246317A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease or condition in a tissue originating from the endoderm |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| EP3672591B1 (en) * | 2018-07-31 | 2024-02-14 | Ascentage Pharma (Suzhou) Co., Ltd. | Synergistic antitumor effect of bcl-2 inhibitor combined with rituximab and/or bendamustine or bcl-2 inhibitor combined with chop |
| CN110776507B (zh) | 2018-07-31 | 2020-12-18 | 苏州亚盛药业有限公司 | Bcl-2抑制剂与化疗药的组合产品及其在预防和/或治疗疾病中的用途 |
| WO2020061048A1 (en) | 2018-09-17 | 2020-03-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Bicistronic chimeric antigen receptors targeting cd19 and cd20 and their uses |
| JP7687952B2 (ja) * | 2018-10-01 | 2025-06-03 | アディセット セラピューティクス， インク． | 血液腫瘍を治療するための遺伝子操作しているγδ－Ｔ細胞及び遺伝子操作していないγδ－Ｔ細胞に関する組成物及び方法 |
| MX2021005007A (es) | 2018-11-01 | 2021-07-21 | Syros Pharmaceuticals Inc | Inhibidores de cinasa 7 dependiente de ciclina (cdk7). |
| AU2019383976B2 (en) | 2018-11-19 | 2025-07-03 | Bt Bidco, Inc. | Methods and devices for treating a disease with biotherapeutics |
| TW202128166A (zh) | 2019-10-21 | 2021-08-01 | 瑞士商諾華公司 | 組合療法 |
| CA3157665A1 (en) | 2019-10-21 | 2021-04-29 | Novartis Ag | Tim-3 inhibitors and uses thereof |
| US11707610B2 (en) | 2019-12-13 | 2023-07-25 | Biora Therapeutics, Inc. | Ingestible device for delivery of therapeutic agent to the gastrointestinal tract |
| CA3185040A1 (en) | 2020-05-26 | 2021-12-02 | Truebinding, Inc. | Methods of treating inflammatory diseases by blocking galectin-3 |
| AU2021378316A1 (en) | 2020-11-13 | 2023-06-01 | Novartis Ag | Combination therapies with chimeric antigen receptor (car)-expressing cells |
| WO2022204282A1 (en) | 2021-03-24 | 2022-09-29 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Bicistronic chimeric antigen receptors designed to reduce retroviral recombination and uses thereof |
| WO2022216942A1 (en) | 2021-04-07 | 2022-10-13 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for the treatment of cancer |
| MX2023012294A (es) * | 2021-04-21 | 2023-10-26 | Celgene Corp | Metodos de tratamiento del linfoma no hodgkin mediante el uso de 2-(2,6-dioxopiperidin-3-il)-4-((2-fluoro-4-((3-morfolinoazetidin- 1-il) metil)benzil)amino)isoindolin-1,3-diona. |
| CA3213632A1 (en) | 2021-04-30 | 2022-11-03 | F. Hoffmann-La Roche Ag | Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate |
| CN119546614A (zh) * | 2022-08-09 | 2025-02-28 | 康百达（四川）生物医药科技有限公司 | 哌嗪类化合物和pd-1抑制剂或pd-l1抑制剂的组合物以及其治疗肿瘤的用途 |
| IL322815A (en) | 2023-02-28 | 2025-10-01 | Juno Therapeutics Inc | Cell therapy for the treatment of systemic autoimmune diseases |
| TW202533828A (zh) * | 2024-02-22 | 2025-09-01 | 瑞典商阿斯特捷利康公司 | Ａｋｔ抑制劑、ｂｃｌ－２抑制劑、及抗ｃｄ２０抗體之治療組合 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US5202238A (en) | 1987-10-27 | 1993-04-13 | Oncogen | Production of chimeric antibodies by homologous recombination |
| US5204244A (en) | 1987-10-27 | 1993-04-20 | Oncogen | Production of chimeric antibodies by homologous recombination |
| PT2180007E (pt) | 1998-04-20 | 2013-11-25 | Roche Glycart Ag | Engenharia de glicosilação de anticorpos para melhorar a citotoxicidade celular dependente de anticorpos |
| CA2332331A1 (en) | 1998-05-15 | 1999-11-25 | Francisco Robert | Treatment of human tumors with radiation and inhibitors of growth factor receptor tyrosine kinases |
| CA2455365C (en) | 2001-08-03 | 2014-07-29 | Glycart Biotechnology Ag | Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity |
| US20040110704A1 (en) | 2002-04-09 | 2004-06-10 | Kyowa Hakko Kogyo Co., Ltd. | Cells of which genome is modified |
| CN101928344B (zh) | 2002-10-17 | 2014-08-13 | 根马布股份公司 | 抗cd20的人单克隆抗体 |
| HRP20100303T1 (hr) | 2003-11-05 | 2010-07-31 | Roche Glycart Ag | Cd20 antitijela s povećanim afinitetom vezivanja fc receptora i efektorskim djelovanjem |
| US7767684B2 (en) | 2003-11-13 | 2010-08-03 | Abbott Laboratories | Apoptosis promoters |
| MX2009002422A (es) | 2006-09-05 | 2009-03-20 | Abbott Lab | Inhibidores bcl para tratar exceso de plaquetas. |
| US20090098118A1 (en) | 2007-10-15 | 2009-04-16 | Thomas Friess | Combination therapy of a type ii anti-cd20 antibody with an anti-bcl-2 active agent |
| US8546399B2 (en) | 2009-05-26 | 2013-10-01 | Abbvie Inc. | Apoptosis inducing agents for the treatment of cancer and immune and autoimmune diseases |
| PH12015500297B1 (en) | 2009-05-26 | 2023-10-20 | Abbvie Ireland Unlimited Co | Adoptosis-inducing agents for the treatment of cancer and immune and automoimmune disease |
| BR112012020102A2 (pt) * | 2010-02-10 | 2016-11-29 | Immunogen Inc | anticorpos cd20 e usos dos mesmos. |
| TWI520960B (zh) * | 2010-05-26 | 2016-02-11 | 艾伯維有限公司 | 用於治療癌症及免疫及自體免疫疾病之細胞凋亡誘導劑 |
| UA113500C2 (xx) | 2010-10-29 | 2017-02-10 | Одержані екструзією розплаву тверді дисперсії, що містять індукуючий апоптоз засіб | |
| KR20180059560A (ko) | 2010-10-29 | 2018-06-04 | 애브비 인코포레이티드 | 아폽토시스―유도제를 포함하는 고체 분산체 |
| PT2643322T (pt) | 2010-11-23 | 2017-11-13 | Abbvie Inc | Sais e formas cristalinas de um agente indutor de apoptose |
| PH12013501006A1 (en) | 2010-11-23 | 2022-03-30 | Abbvie Ireland Unlimited Co | Methods of treatment using selective bcl-2 inhibitors |
| CN104768581A (zh) | 2012-09-07 | 2015-07-08 | 吉宁特有限公司 | II型抗CD20抗体与选择性Bcl-2抑制剂的组合治疗 |
| US9006438B2 (en) | 2013-03-13 | 2015-04-14 | Abbvie Inc. | Processes for the preparation of an apoptosis-inducing agent |
| CN107847600B (zh) | 2015-05-26 | 2021-09-03 | 豪夫迈·罗氏有限公司 | 抗CD20抗体与Bcl-2抑制剂和MDM2抑制剂的组合疗法 |
| AU2016349279A1 (en) * | 2015-11-03 | 2018-05-10 | Board Of Regents, The University Of Texas System | Combination of Bcl-2 inhibitor and MEK inhibitor for the treatment of cancer |
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2013
- 2013-09-06 CN CN201380057990.6A patent/CN104768581A/zh active Pending
- 2013-09-06 EP EP21173041.1A patent/EP3919079A1/en active Pending
- 2013-09-06 KR KR1020157008862A patent/KR102158467B1/ko active Active
- 2013-09-06 CN CN202010088179.6A patent/CN111437386A/zh active Pending
- 2013-09-06 KR KR1020207026653A patent/KR20200110711A/ko active Pending
- 2013-09-06 JP JP2015531246A patent/JP6408993B2/ja active Active
- 2013-09-06 CN CN202010088180.9A patent/CN111481552A/zh active Pending
- 2013-09-06 RU RU2015112576A patent/RU2648476C2/ru active
- 2013-09-06 MX MX2015002947A patent/MX2015002947A/es active IP Right Grant
- 2013-09-06 HK HK16100331.0A patent/HK1212240A1/xx unknown
- 2013-09-06 EP EP13767170.7A patent/EP2892557A1/en not_active Withdrawn
- 2013-09-06 US US14/020,761 patent/US9539251B2/en active Active
- 2013-09-06 CA CA2884307A patent/CA2884307A1/en active Pending
- 2013-09-06 NZ NZ630166A patent/NZ630166A/en unknown
- 2013-09-06 WO PCT/US2013/058557 patent/WO2014039855A1/en not_active Ceased
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2016
- 2016-11-30 US US15/365,595 patent/US11413282B2/en active Active
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2018
- 2018-07-03 JP JP2018126675A patent/JP6637119B2/ja active Active
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2019
- 2019-12-18 JP JP2019227891A patent/JP2020063279A/ja active Pending
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2020
- 2020-03-23 US US16/827,650 patent/US10993942B2/en active Active
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2021
- 2021-02-26 US US17/187,468 patent/US11110087B2/en active Active
- 2021-03-05 US US17/193,795 patent/US20220008413A1/en not_active Abandoned
- 2021-08-05 US US17/395,366 patent/US20220211696A1/en not_active Abandoned
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2022
- 2022-03-30 US US17/709,324 patent/US20220265642A1/en not_active Abandoned
- 2022-04-08 JP JP2022064357A patent/JP2022091996A/ja active Pending
- 2022-06-07 US US17/834,709 patent/US11590128B2/en active Active
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2023
- 2023-01-20 US US18/157,680 patent/US20230226045A1/en not_active Abandoned
- 2023-03-28 US US18/191,810 patent/US20230255959A1/en not_active Abandoned
- 2023-09-07 US US18/463,252 patent/US20240000776A1/en not_active Abandoned
- 2023-11-10 US US18/506,606 patent/US20240108616A1/en not_active Abandoned
- 2023-12-08 US US18/534,251 patent/US20240180901A1/en not_active Abandoned
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2024
- 2024-04-11 JP JP2024063799A patent/JP2024095793A/ja active Pending
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2025
- 2025-01-17 US US19/030,370 patent/US20250152582A1/en not_active Abandoned