|
US20030108545A1
(en)
*
|
1994-02-10 |
2003-06-12 |
Patricia Rockwell |
Combination methods of inhibiting tumor growth with a vascular endothelial growth factor receptor antagonist
|
|
US7060808B1
(en)
*
|
1995-06-07 |
2006-06-13 |
Imclone Systems Incorporated |
Humanized anti-EGF receptor monoclonal antibody
|
|
DE69633565T3
(de)
|
1995-06-15 |
2013-01-17 |
Crucell Holland B.V. |
Verpackungssysteme für humane, menschliche adenoviren, zur verwendung in die gentherapie
|
|
US6417168B1
(en)
|
1998-03-04 |
2002-07-09 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods of treating tumors
|
|
EP1745799B1
(en)
|
1998-03-04 |
2015-09-02 |
The Trustees of The University of Pennsylvania |
Compositions and methods of treating tumors
|
|
US20030224001A1
(en)
*
|
1998-03-19 |
2003-12-04 |
Goldstein Neil I. |
Antibody and antibody fragments for inhibiting the growth of tumors
|
|
ZA200007412B
(en)
*
|
1998-05-15 |
2002-03-12 |
Imclone Systems Inc |
Treatment of human tumors with radiation and inhibitors of growth factor receptor tyrosine kinases.
|
|
US6929946B1
(en)
*
|
1998-11-20 |
2005-08-16 |
Crucell Holland B.V. |
Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells
|
|
US7393823B1
(en)
|
1999-01-20 |
2008-07-01 |
Oregon Health And Science University |
HER-2 binding antagonists
|
|
US7625859B1
(en)
*
|
2000-02-16 |
2009-12-01 |
Oregon Health & Science University |
HER-2 binding antagonists
|
|
US7396810B1
(en)
*
|
2000-08-14 |
2008-07-08 |
Oregon Health Sciences University |
Compositions and methods for treating cancer by modulating HER-2 and EGF receptors
|
|
EE200100603A
(et)
*
|
1999-05-14 |
2003-02-17 |
Imclone Systems Incorporated |
Inimese refraktaarsete kasvajate ravi epidermaalse kasvufaktori retseptori antagonistidega
|
|
WO2003104467A1
(en)
*
|
2002-04-25 |
2003-12-18 |
Crucell Holland B.V. |
Means and methods for the production of adenovirus vectors
|
|
US20050232900A1
(en)
*
|
1999-05-18 |
2005-10-20 |
Crucell Holland B.V. |
Serotype of adenovirus and uses thereof
|
|
US6913922B1
(en)
*
|
1999-05-18 |
2005-07-05 |
Crucell Holland B.V. |
Serotype of adenovirus and uses thereof
|
|
US20030086924A1
(en)
*
|
1999-06-25 |
2003-05-08 |
Genentech, Inc. |
Treatment with anti-ErbB2 antibodies
|
|
US20040013667A1
(en)
*
|
1999-06-25 |
2004-01-22 |
Genentech, Inc. |
Treatment with anti-ErbB2 antibodies
|
|
DE60033658T2
(de)
*
|
1999-06-25 |
2007-11-22 |
Genentech, Inc., South San Francisco |
Behandlung von prostata-krebs mit anti-erbb2 antikörpern
|
|
US7041292B1
(en)
|
1999-06-25 |
2006-05-09 |
Genentech, Inc. |
Treating prostate cancer with anti-ErbB2 antibodies
|
|
US6949245B1
(en)
*
|
1999-06-25 |
2005-09-27 |
Genentech, Inc. |
Humanized anti-ErbB2 antibodies and treatment with anti-ErbB2 antibodies
|
|
EP1280923A2
(en)
*
|
2000-04-28 |
2003-02-05 |
Millennium Pharmaceuticals, Inc. |
14094, a human trypsin family member and uses thereof
|
|
AU2001295002B2
(en)
*
|
2000-08-09 |
2007-05-31 |
Imclone Systems Incorporated |
Treatment of hyperproliferative diseases with epidermal growth factor receptor antagonists
|
|
US8039261B2
(en)
*
|
2000-11-17 |
2011-10-18 |
Vascular Biogenics Ltd. |
Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
|
|
US8071740B2
(en)
*
|
2000-11-17 |
2011-12-06 |
Vascular Biogenics Ltd. |
Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
|
|
US20070286845A1
(en)
*
|
2000-11-17 |
2007-12-13 |
Vascular Biogenics Ltd. |
Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
|
|
US20050239738A1
(en)
*
|
2000-11-17 |
2005-10-27 |
Rupert Schmidt-Ullrich |
Genetic inhibition of epidermal growth factor receptor function and carcinoma cell radiosensitization
|
|
AU2003222427B8
(en)
|
2000-11-17 |
2010-04-29 |
Vascular Biogenics Ltd. |
Promoters exhibiting endothelial cell specificity and methods of using same
|
|
US20100282634A1
(en)
*
|
2000-11-17 |
2010-11-11 |
Dror Harats |
Promoters Exhibiting Endothelial Cell Specificity and Methods of Using Same for Regulation of Angiogenesis
|
|
US20080008704A1
(en)
*
|
2001-03-16 |
2008-01-10 |
Mark Rubin |
Methods of treating colorectal cancer with anti-epidermal growth factor antibodies
|
|
JP4398644B2
(ja)
|
2001-04-06 |
2010-01-13 |
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルベニア |
ErbB界面ペプチド擬態およびその使用方法
|
|
DK1392359T4
(da)
|
2001-05-11 |
2013-06-10 |
Ludwig Inst For Cancer Res Ltd |
Specifikke bindingsproteiner og deres anvendelser.
|
|
US20100056762A1
(en)
|
2001-05-11 |
2010-03-04 |
Old Lloyd J |
Specific binding proteins and uses thereof
|
|
US7595378B2
(en)
|
2001-06-13 |
2009-09-29 |
Genmab A/S |
Human monoclonal antibodies to epidermal growth factor receptor (EGFR)
|
|
AU2002326531A1
(en)
*
|
2001-08-03 |
2003-02-17 |
The Trustees Of The University Of Pennsylvania |
Monoclonal antibodies to activated erbb family members and methods of use thereof
|
|
WO2003061559A2
(en)
*
|
2001-10-12 |
2003-07-31 |
University Of Vermont And State Agricultural College |
Binding peptides specific for the extracellular domain of erbb2 and uses therefor
|
|
EP1436313B1
(en)
*
|
2001-10-19 |
2010-09-22 |
Vascular Biogenics Ltd. |
Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
|
|
US7179785B2
(en)
*
|
2001-11-21 |
2007-02-20 |
The Trustees Of The University Of Pennsylvania |
Compounds that bind to p185 and methods of using the same
|
|
US20030202973A1
(en)
*
|
2002-04-29 |
2003-10-30 |
Dr. George Pieczenik |
Treatment of refractory human tumors with epidermal growth factor receptor and HER1 mitogenic ligand (EGFRML) antagonists
|
|
US20040229294A1
(en)
*
|
2002-05-21 |
2004-11-18 |
Po-Ying Chan-Hui |
ErbB surface receptor complexes as biomarkers
|
|
US7402397B2
(en)
|
2002-05-21 |
2008-07-22 |
Monogram Biosciences, Inc. |
Detecting and profiling molecular complexes
|
|
US20040229380A1
(en)
*
|
2002-05-21 |
2004-11-18 |
Po-Ying Chan-Hui |
ErbB heterodimers as biomarkers
|
|
WO2003099845A2
(en)
|
2002-05-23 |
2003-12-04 |
Trustees Of The University Of Pennsylvania |
Fas peptide mimetics and uses thereof
|
|
WO2004005320A2
(en)
*
|
2002-07-03 |
2004-01-15 |
The Curators Of The University Of Missouri |
ErbB-2 RECEPTOR TARGETING PEPTIDE
|
|
HUP0600340A3
(en)
*
|
2002-07-15 |
2011-06-28 |
Genentech Inc |
Methods for identifying tumors that are responsive to treatment with anti-erbb2 antibodies
|
|
EP1572972A4
(en)
*
|
2002-11-21 |
2007-11-21 |
Genentech Inc |
THERAPY OF NON-MALIGNER DISEASES OR DISORDER WITH ANTI-ERBB2 ANTIBODIES
|
|
EP1622941A2
(en)
*
|
2003-03-20 |
2006-02-08 |
ImClone Systems Incorporated |
Method of producing an antibody to epidermal growth factor receptor
|
|
BRPI0408928A
(pt)
*
|
2003-04-01 |
2006-09-12 |
Monogram Biosciences Inc |
métodos para determinar uma situação de doença em um paciente, uma situação apoptótica de células em uma amostra, e uma situação de um cáncer em um paciente
|
|
WO2005037071A2
(en)
*
|
2003-10-14 |
2005-04-28 |
Monogram Biosciences, Inc. |
Receptor tyrosine kinase signaling pathway analysis for diagnosis and therapy
|
|
ES2387809T3
(es)
*
|
2004-03-19 |
2012-10-02 |
Imclone Llc |
Anticuerpo frente al receptor del factor de crecimiento epidérmico humano
|
|
US20110142822A1
(en)
*
|
2004-06-14 |
2011-06-16 |
Kussie Paul H |
Crystal of egfr extracellular domain and cetuximab fab fragment, and uses thereof
|
|
WO2006042002A2
(en)
*
|
2004-10-05 |
2006-04-20 |
Oregon Health And Science University |
Compositions and methods for treating disease
|
|
US20070009972A1
(en)
*
|
2005-02-16 |
2007-01-11 |
Ginger Chao |
Epidermal growth factor receptor polypeptides and antibodies
|
|
RS53128B
(sr)
|
2005-02-23 |
2014-06-30 |
Genentech Inc. |
Produžavanje vremena progresije bolesti ili preživljavanja kod pacijenata obolelih od kancera jajnika korišćenjem pertuzumaba
|
|
US20060204505A1
(en)
*
|
2005-03-08 |
2006-09-14 |
Sliwkowski Mark X |
Methods for identifying tumors responsive to treatment with HER dimerization inhibitors (HDIs)
|
|
US8465732B2
(en)
|
2007-01-19 |
2013-06-18 |
Cornell Research Foundation, Inc. |
Endothelial cells expressing adenovirus E4ORF1 and methods of use thereof
|
|
US9090693B2
(en)
|
2007-01-25 |
2015-07-28 |
Dana-Farber Cancer Institute |
Use of anti-EGFR antibodies in treatment of EGFR mutant mediated disease
|
|
NZ579644A
(en)
|
2007-02-16 |
2012-05-25 |
Merrimack Pharmaceuticals Inc |
Antibodies against erbb3 and uses thereof
|
|
MX2009008981A
(es)
|
2007-03-02 |
2009-09-02 |
Genentech Inc |
Prediccion de respuesta a un inhibidor her.
|
|
JP5618549B2
(ja)
|
2007-03-15 |
2014-11-05 |
ルードヴィッヒ インスティテュート フォー キャンサーリサーチ リミテッド |
Egfr抗体及びsrc阻害剤を用いる治療方法及び関連製剤
|
|
WO2008154249A2
(en)
|
2007-06-08 |
2008-12-18 |
Genentech, Inc. |
Gene expression markers of tumor resistance to her2 inhibitor treatment
|
|
JP5532486B2
(ja)
|
2007-08-14 |
2014-06-25 |
ルードヴィッヒ インスティテュート フォー キャンサー リサーチ |
Egf受容体を標的とするモノクローナル抗体175ならびにその誘導体および用途
|
|
RU2010119556A
(ru)
*
|
2007-10-16 |
2011-11-27 |
Симфоген А/С (Dk) |
Композиции, содержащие оптимизированные мультимеры her1 и her3, и способы их применения
|
|
US8557242B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
ERBB2 antibodies comprising modular recognition domains
|
|
EA021967B1
(ru)
|
2008-01-03 |
2015-10-30 |
Дзе Скриппс Рисерч Инститьют |
Доставка антител посредством модульного домена распознавания
|
|
US8454960B2
(en)
|
2008-01-03 |
2013-06-04 |
The Scripps Research Institute |
Multispecific antibody targeting and multivalency through modular recognition domains
|
|
US8557243B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
EFGR antibodies comprising modular recognition domains
|
|
US8574577B2
(en)
|
2008-01-03 |
2013-11-05 |
The Scripps Research Institute |
VEGF antibodies comprising modular recognition domains
|
|
KR20110044905A
(ko)
|
2008-08-15 |
2011-05-02 |
메리맥 파마슈티컬즈, 인크. |
치료제에 대한 세포의 반응을 예측하는 방법 및 시스템
|
|
JP2012507299A
(ja)
*
|
2008-10-31 |
2012-03-29 |
バイオジェン・アイデック・エムエイ・インコーポレイテッド |
Light標的分子およびその使用
|
|
KR20150036824A
(ko)
|
2009-03-20 |
2015-04-07 |
제넨테크, 인크. |
이중특이적 항-her 항체
|
|
US8895001B2
(en)
|
2010-03-11 |
2014-11-25 |
Merrimack Pharmaceuticals, Inc. |
Use of ErbB3 inhibitors in the treatment of triple negative and basal-like breast cancers
|
|
WO2011146568A1
(en)
|
2010-05-19 |
2011-11-24 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
|
NZ604007A
(en)
|
2010-05-27 |
2015-03-27 |
Genmab As |
Monoclonal antibodies against her2 epitope
|
|
IL299365A
(en)
|
2010-05-27 |
2023-02-01 |
Genmab As |
Monoclonal antibodies against 2HER
|
|
WO2012009705A1
(en)
|
2010-07-15 |
2012-01-19 |
Zyngenia, Inc. |
Ang-2 binding complexes and uses thereof
|
|
US9427458B2
(en)
*
|
2010-07-22 |
2016-08-30 |
Consejo Nacional De Investigaciones Cientificas Y Tecnicas, Conicet |
Methods for inhibiting cancer cell proliferation
|
|
TW201302793A
(zh)
|
2010-09-03 |
2013-01-16 |
Glaxo Group Ltd |
新穎之抗原結合蛋白
|
|
WO2012143524A2
(en)
|
2011-04-20 |
2012-10-26 |
Genmab A/S |
Bispecific antibodies against her2 and cd3
|
|
DK2714738T3
(en)
|
2011-05-24 |
2019-01-28 |
Zyngenia Inc |
MULTIVALENT AND MONOVALENT MULTISPECIFIC COMPLEXES AND THEIR APPLICATIONS
|
|
WO2013075127A1
(en)
|
2011-11-17 |
2013-05-23 |
Medrad, Inc. |
Methods and techniques for collecting, reporting, and managing information about medical diagnostic procedures
|
|
CN108424456B
(zh)
|
2011-11-23 |
2022-04-26 |
医学免疫有限责任公司 |
特异于her3的结合分子及其用途
|
|
AU2012346540C1
(en)
|
2011-11-30 |
2019-07-04 |
Genentech, Inc. |
ErbB3 mutations in cancer
|
|
CN104136464A
(zh)
*
|
2012-02-23 |
2014-11-05 |
U3制药有限公司 |
用于调节放射敏感性的her3抑制剂
|
|
WO2013148315A1
(en)
|
2012-03-27 |
2013-10-03 |
Genentech, Inc. |
Diagnosis and treatments relating to her3 inhibitors
|
|
WO2014159917A2
(en)
*
|
2013-03-14 |
2014-10-02 |
Georgetown University |
Treatment for exposure to nerve agent
|
|
MX2015013163A
(es)
|
2013-03-15 |
2016-04-04 |
Zyngenia Inc |
Complejos multiespecificos multivalente y monovalentes y sus usos.
|
|
EP3030268B1
(en)
*
|
2013-08-09 |
2022-07-27 |
The Trustees Of The University Of Pennsylvania |
Combination of ifn-gamma with anti-erbb antibody for the treatment of cancers
|
|
US11446516B2
(en)
|
2013-08-09 |
2022-09-20 |
The Trustees Of The University Of Pennsylvania |
Methods of increasing response to cancer radiation therapy
|
|
US11305012B2
(en)
|
2013-09-24 |
2022-04-19 |
Medimmune, Llc |
Binding molecules specific for HER3 and uses thereof
|
|
WO2015100459A2
(en)
|
2013-12-27 |
2015-07-02 |
Merrimack Pharmaceuticals, Inc. |
Biomarker profiles for predicting outcomes of cancer therapy with erbb3 inhibitors and/or chemotherapies
|
|
US10745490B2
(en)
|
2014-04-11 |
2020-08-18 |
Celldex Therapeutics, Inc. |
Anti-ErbB antibodies and methods of use thereof
|
|
EP3584312A1
(en)
*
|
2014-06-27 |
2019-12-25 |
Angiocrine Bioscience, Inc. |
Neural cells expressing adenovirus e4orf1, and methods of making and using the same
|
|
WO2016168634A1
(en)
*
|
2015-04-17 |
2016-10-20 |
Bulldog Pharmaceuticals, Inc. |
Biomarkers related to treatment of cancer with her3 and egfr inhibitors
|
|
US10184006B2
(en)
|
2015-06-04 |
2019-01-22 |
Merrimack Pharmaceuticals, Inc. |
Biomarkers for predicting outcomes of cancer therapy with ErbB3 inhibitors
|
|
WO2018200505A1
(en)
|
2017-04-24 |
2018-11-01 |
Genentech, Inc. |
Erbb2/her2 mutations in the transmbrane or juxtamembrane domain
|
|
US11430558B2
(en)
|
2017-07-07 |
2022-08-30 |
Bayer Healthcare Llc |
System, method, and computer program product for peer exchange of data between injection systems
|
|
WO2019185164A1
(en)
|
2018-03-29 |
2019-10-03 |
Hummingbird Bioscience Holdings Pte. Ltd. |
Her3 antigen-binding molecules
|
|
MX2023008826A
(es)
|
2021-02-01 |
2023-09-15 |
Regenxbio Inc |
Terapia génica para lipofuscinosis neuronal ceroidea.
|
|
US12245355B2
(en)
|
2021-02-19 |
2025-03-04 |
Mevion Medical Systems, Inc. |
Gantry for a particle therapy system
|
|
EP4402175A4
(en)
*
|
2021-09-13 |
2025-10-08 |
Univ Texas |
LILRB2-SPECIFIC MONOCLONAL ANTIBODIES AND METHODS OF USE THEREOF
|
|
AU2023375470A1
(en)
*
|
2022-11-08 |
2025-06-19 |
Purdue Research Foundation |
Multivalent multispecific conjugates and related compositions and methods of use
|