JP2012012402A5 - - Google Patents
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- Publication number
- JP2012012402A5 JP2012012402A5 JP2011178577A JP2011178577A JP2012012402A5 JP 2012012402 A5 JP2012012402 A5 JP 2012012402A5 JP 2011178577 A JP2011178577 A JP 2011178577A JP 2011178577 A JP2011178577 A JP 2011178577A JP 2012012402 A5 JP2012012402 A5 JP 2012012402A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- binding
- antigen
- fragment
- gpr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/266,464 US6329159B1 (en) | 1999-03-11 | 1999-03-11 | Anti-GPR-9-6 antibodies and methods of identifying agents which modulate GPR-9-6 function |
| US09/266,464 | 1999-03-11 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000604070A Division JP5112578B2 (ja) | 1999-03-11 | 2000-03-10 | 抗gpr−9−6および抗teck抗体ならびにgpr−9−6およびteckの機能の調節因子の同定方法。 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012012402A JP2012012402A (ja) | 2012-01-19 |
| JP2012012402A5 true JP2012012402A5 (cg-RX-API-DMAC7.html) | 2012-10-11 |
| JP5933204B2 JP5933204B2 (ja) | 2016-06-08 |
Family
ID=23014693
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000604070A Expired - Lifetime JP5112578B2 (ja) | 1999-03-11 | 2000-03-10 | 抗gpr−9−6および抗teck抗体ならびにgpr−9−6およびteckの機能の調節因子の同定方法。 |
| JP2011178577A Expired - Lifetime JP5933204B2 (ja) | 1999-03-11 | 2011-08-17 | 抗gpr−9−6および抗teck抗体ならびにgpr−9−6およびteckの機能の調節因子の同定方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000604070A Expired - Lifetime JP5112578B2 (ja) | 1999-03-11 | 2000-03-10 | 抗gpr−9−6および抗teck抗体ならびにgpr−9−6およびteckの機能の調節因子の同定方法。 |
Country Status (7)
| Country | Link |
|---|---|
| US (6) | US6329159B1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1157043B2 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5112578B2 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE517123T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU771603B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2365230C (cg-RX-API-DMAC7.html) |
| WO (1) | WO2000053635A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999062505A2 (en) * | 1998-06-01 | 1999-12-09 | Ortho-Mcneil Pharmaceutical, Inc. | Method for treating neurodegenerative disorders |
| US20050100548A1 (en) * | 2001-07-24 | 2005-05-12 | Biogen Idec Ma Inc. | BAFF, inhibitors thereof and their use in the modulation of B-cell response |
| US6329159B1 (en) | 1999-03-11 | 2001-12-11 | Millennium Pharmaceuticals, Inc. | Anti-GPR-9-6 antibodies and methods of identifying agents which modulate GPR-9-6 function |
| US6698636B2 (en) * | 2000-09-28 | 2004-03-02 | June Angus | Waist pouch |
| US7468253B2 (en) * | 2001-06-07 | 2008-12-23 | Chemocentryx, Inc. | Method for multiple chemokine receptor screening for antagonists using RAM assay |
| ATE347695T1 (de) * | 2001-06-07 | 2006-12-15 | Chemocentryx Inc | Zellwanderungsassay |
| NO20013192L (no) * | 2001-06-25 | 2002-12-27 | Medinnova As | Metode for monitering av T-celler |
| US7871619B2 (en) * | 2001-11-30 | 2011-01-18 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
| US7442512B2 (en) * | 2001-11-30 | 2008-10-28 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
| US7253007B2 (en) * | 2001-11-30 | 2007-08-07 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
| US7413866B2 (en) * | 2001-11-30 | 2008-08-19 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
| WO2003095967A2 (en) * | 2002-05-14 | 2003-11-20 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with chemokine receptor 9(ccr9) |
| WO2003099773A1 (en) | 2002-05-24 | 2003-12-04 | Millennium Pharmaceuticals, Inc. | Ccr9 inhibitors and methods of use thereof |
| US20120135415A1 (en) * | 2002-11-15 | 2012-05-31 | Morehouse School Of Medicine | Detecting cancer with anti-cxcl13 and anti-cxcr5 antibodies |
| US9233120B2 (en) | 2002-11-15 | 2016-01-12 | Jyant Technologies | Anti-CCL25 and anti-CCR9 antibodies for the prevention and treatment of cancer and cancer cell migration |
| US7919083B2 (en) * | 2002-11-15 | 2011-04-05 | Morehouse School Of Medicine | Anti-chemokine and associated receptors antibodies for inhibition of growth of neoplasms |
| US8512701B2 (en) * | 2002-11-15 | 2013-08-20 | Morehouse School Of Medicine | Anti-CXCL13 and anti-CXCR5 antibodies for the prevention and treatment of cancer and cancer cell migration |
| US8658377B2 (en) | 2002-11-15 | 2014-02-25 | Morehouse School Of Medicine | Detecting cancer with anti-CCL25 and anti-CCR9 antibodies |
| AU2003294290A1 (en) * | 2002-11-15 | 2004-06-15 | Morehouse School Of Medicine | Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation. |
| KR101061352B1 (ko) * | 2002-12-20 | 2011-08-31 | 케모센트릭스 | 인간 종양-발현된 ccxckr2의 저해물질 |
| DK1631312T3 (da) * | 2003-04-23 | 2009-01-19 | Medarex Inc | Sammensætning og fremstillingsmåde til behandling af inflammatorisk tarmsygdom |
| US20100247540A1 (en) * | 2003-10-30 | 2010-09-30 | Chemocentryx, Inc. | Methods and Compositions For Modulating Angiogenesis |
| AU2005241431A1 (en) * | 2004-04-16 | 2005-11-17 | Genentech, Inc. | Assay for antibodies |
| RU2412202C2 (ru) | 2004-06-21 | 2011-02-20 | Медарекс, Инк. | Антитела рецептора 1 интерферона альфа и их применение |
| ES2434852T3 (es) * | 2005-04-21 | 2013-12-17 | Chemocentryx, Inc. | Anticuerpos que se unen a CCX-CKR2 |
| CA2883711A1 (en) | 2012-09-07 | 2014-03-13 | The Governors Of The University Of Alberta | Methods and compositions for diagnosis of inflammatory liver disease |
| EP2876114A1 (en) * | 2013-11-25 | 2015-05-27 | Consejo Superior De Investigaciones Científicas | Antibodies against CCR9 and applications thereof |
| WO2017140793A1 (en) | 2016-02-16 | 2017-08-24 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Modulators of ccr9 for treating tumor resistance to immune responses |
| EP3416640A1 (en) | 2016-02-16 | 2018-12-26 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Modulators of tumor immune resistance for the treatment of cancer |
| CN110087530A (zh) | 2016-12-07 | 2019-08-02 | 普罗根尼蒂公司 | 胃肠道检测方法、装置和系统 |
| WO2018112264A1 (en) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor |
| CN116726362A (zh) | 2018-11-19 | 2023-09-12 | 比奥拉治疗股份有限公司 | 用生物治疗剂治疗疾病的方法和装置 |
| CN115666704B (zh) | 2019-12-13 | 2025-09-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| CN118843478A (zh) | 2022-02-03 | 2024-10-25 | 圣洛克生物制药有限公司 | 用于癌症的包括抗ccr9抗体和长春新碱的联合疗法 |
| JP7368678B1 (ja) * | 2023-04-26 | 2023-10-25 | イミュニティリサーチ株式会社 | Cd4+t細胞集団中の特定の細胞亜集団の相対量の測定方法 |
| EP4578874A1 (en) | 2023-12-29 | 2025-07-02 | SunRock Biopharma S.L. | Anti-ccr9 antibody |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US18167A (en) * | 1857-09-08 | Improvement in blast-furnaces | ||
| US5440021A (en) * | 1991-03-29 | 1995-08-08 | Chuntharapai; Anan | Antibodies to human IL-8 type B receptor |
| US5652133A (en) | 1993-01-28 | 1997-07-29 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Cloning and expression of the human macrophage inflammatory protein-1.alpha.α) /rantes receptor |
| ATE428785T1 (de) * | 1996-03-01 | 2009-05-15 | Euroscreen Sa | Aktive und inactive cc-chemokinrezeptoren und nukleinsäuremoleküle, die für diesen rezeptor kodieren |
| IL127551A0 (en) † | 1996-06-17 | 1999-10-28 | Human Genome Sciences Inc | Chemokine beta-15 |
| US5981231A (en) | 1996-06-17 | 1999-11-09 | Human Genome Sciences, Inc. | Polynucleotides encoding chemokine β-15 |
| US6723520B2 (en) * | 1996-07-05 | 2004-04-20 | Schering Corporation | Antibodies that bind chemokine teck |
| EP0909321A2 (en) | 1996-07-05 | 1999-04-21 | Schering Corporation | Mammalian chemokine reagents |
| ATE360689T1 (de) * | 1996-09-10 | 2007-05-15 | Kocher Theodor Inst | Cxcr3 chemokine rezeptor, antikoerper, nukleinsaeure und deren verfahren zur anwendung |
| AU6132698A (en) | 1997-01-23 | 1998-08-18 | Schering Corporation | Mammalian chemokines; receptors; reagents; uses |
| EP0878542A3 (en) * | 1997-04-22 | 2000-04-19 | Smithkline Beecham Corporation | cDNA clone HMTMF81 that encodes a novel human 7-transmembrane receptor |
| WO1999007738A2 (en) * | 1997-08-06 | 1999-02-18 | Regeneron Pharmaceuticals, Inc. | Human orphan receptor ntr-1 |
| US6329159B1 (en) | 1999-03-11 | 2001-12-11 | Millennium Pharmaceuticals, Inc. | Anti-GPR-9-6 antibodies and methods of identifying agents which modulate GPR-9-6 function |
| YU78601A (sh) * | 1999-05-05 | 2005-07-19 | Aventis Pharma Deutschland Gmbh. | 1-(p-tienilbenzil)-imidazoli kao agonisti angiotenzin-(1-7)- receptora, postupak za njihovu proizvodnju, njihova primena i farmaceutski preparati koji ih sadrže |
| CA2396779A1 (en) * | 2000-01-07 | 2001-07-12 | Stichting Klinishce Farmacologie Groningen | Gene therapy to promote angiogenesis and/or the treatment of heart failure |
| CN101077867B (zh) | 2002-11-18 | 2012-10-10 | 坎莫森特里克斯公司 | 芳基磺酰胺 |
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1999
- 1999-03-11 US US09/266,464 patent/US6329159B1/en not_active Expired - Lifetime
-
2000
- 2000-03-10 JP JP2000604070A patent/JP5112578B2/ja not_active Expired - Lifetime
- 2000-03-10 AU AU35226/00A patent/AU771603B2/en not_active Expired
- 2000-03-10 AT AT00913864T patent/ATE517123T1/de not_active IP Right Cessation
- 2000-03-10 WO PCT/US2000/006240 patent/WO2000053635A1/en not_active Ceased
- 2000-03-10 EP EP00913864.5A patent/EP1157043B2/en not_active Expired - Lifetime
- 2000-03-10 US US09/522,752 patent/US6936248B1/en not_active Expired - Lifetime
- 2000-03-10 CA CA2365230A patent/CA2365230C/en not_active Expired - Lifetime
-
2001
- 2001-09-13 US US09/952,385 patent/US6689570B2/en not_active Expired - Lifetime
- 2001-09-28 US US09/966,755 patent/US6884574B2/en not_active Expired - Lifetime
- 2001-10-23 US US10/000,759 patent/US7485301B2/en not_active Expired - Lifetime
-
2005
- 2005-04-19 US US11/109,349 patent/US7381412B2/en not_active Expired - Lifetime
-
2011
- 2011-08-17 JP JP2011178577A patent/JP5933204B2/ja not_active Expired - Lifetime