ATE517123T1 - Anti-gpr-9-6 und anti-teck gerichtete antikörper und verfahren zur identifizierung von modulatoren der gpr-9-6 und teck funktion - Google Patents
Anti-gpr-9-6 und anti-teck gerichtete antikörper und verfahren zur identifizierung von modulatoren der gpr-9-6 und teck funktionInfo
- Publication number
- ATE517123T1 ATE517123T1 AT00913864T AT00913864T ATE517123T1 AT E517123 T1 ATE517123 T1 AT E517123T1 AT 00913864 T AT00913864 T AT 00913864T AT 00913864 T AT00913864 T AT 00913864T AT E517123 T1 ATE517123 T1 AT E517123T1
- Authority
- AT
- Austria
- Prior art keywords
- gpr
- teck
- function
- binding
- identifying modulators
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Reproductive Health (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/266,464 US6329159B1 (en) | 1999-03-11 | 1999-03-11 | Anti-GPR-9-6 antibodies and methods of identifying agents which modulate GPR-9-6 function |
PCT/US2000/006240 WO2000053635A1 (en) | 1999-03-11 | 2000-03-10 | Anti-gpr-9-6 and anti-teck antibodies and methods of identifying modulators of gpr-9-6 and teck functions |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE517123T1 true ATE517123T1 (de) | 2011-08-15 |
Family
ID=23014693
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00913864T ATE517123T1 (de) | 1999-03-11 | 2000-03-10 | Anti-gpr-9-6 und anti-teck gerichtete antikörper und verfahren zur identifizierung von modulatoren der gpr-9-6 und teck funktion |
Country Status (7)
Country | Link |
---|---|
US (6) | US6329159B1 (de) |
EP (1) | EP1157043B2 (de) |
JP (2) | JP5112578B2 (de) |
AT (1) | ATE517123T1 (de) |
AU (1) | AU771603B2 (de) |
CA (1) | CA2365230C (de) |
WO (1) | WO2000053635A1 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
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DE69913520T2 (de) * | 1998-06-01 | 2004-11-25 | Ortho-Mcneil Pharmaceutical, Inc. | Tetrahydronaphtalene verbindungen und deren verwendung zur behandlung von neurodegenerativen krankheiten |
US20050100548A1 (en) * | 2001-07-24 | 2005-05-12 | Biogen Idec Ma Inc. | BAFF, inhibitors thereof and their use in the modulation of B-cell response |
US6329159B1 (en) | 1999-03-11 | 2001-12-11 | Millennium Pharmaceuticals, Inc. | Anti-GPR-9-6 antibodies and methods of identifying agents which modulate GPR-9-6 function |
US6698636B2 (en) * | 2000-09-28 | 2004-03-02 | June Angus | Waist pouch |
US7468253B2 (en) * | 2001-06-07 | 2008-12-23 | Chemocentryx, Inc. | Method for multiple chemokine receptor screening for antagonists using RAM assay |
WO2002101350A2 (en) * | 2001-06-07 | 2002-12-19 | Chemocentryx | Cell migration assay |
NO20013192L (no) * | 2001-06-25 | 2002-12-27 | Medinnova As | Metode for monitering av T-celler |
US7253007B2 (en) * | 2001-11-30 | 2007-08-07 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
US7413866B2 (en) * | 2001-11-30 | 2008-08-19 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
US7442512B2 (en) * | 2001-11-30 | 2008-10-28 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
US7871619B2 (en) * | 2001-11-30 | 2011-01-18 | Chemocentryx, Inc. | Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors |
WO2003095967A2 (en) * | 2002-05-14 | 2003-11-20 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with chemokine receptor 9(ccr9) |
WO2003099773A1 (en) | 2002-05-24 | 2003-12-04 | Millennium Pharmaceuticals, Inc. | Ccr9 inhibitors and methods of use thereof |
US20120135415A1 (en) * | 2002-11-15 | 2012-05-31 | Morehouse School Of Medicine | Detecting cancer with anti-cxcl13 and anti-cxcr5 antibodies |
US8658377B2 (en) | 2002-11-15 | 2014-02-25 | Morehouse School Of Medicine | Detecting cancer with anti-CCL25 and anti-CCR9 antibodies |
WO2004045526A2 (en) * | 2002-11-15 | 2004-06-03 | Morehouse School Of Medicine | Anti-chemokine and associated receptors antibodies for inhibition of growth of neoplasms |
US9233120B2 (en) | 2002-11-15 | 2016-01-12 | Jyant Technologies | Anti-CCL25 and anti-CCR9 antibodies for the prevention and treatment of cancer and cancer cell migration |
US8512701B2 (en) | 2002-11-15 | 2013-08-20 | Morehouse School Of Medicine | Anti-CXCL13 and anti-CXCR5 antibodies for the prevention and treatment of cancer and cancer cell migration |
US7964194B2 (en) * | 2002-11-15 | 2011-06-21 | Morehouse School Of Medicine | Anti-chemokine and associated receptor antibodies and uses for inhibition of inflammation |
KR101061352B1 (ko) * | 2002-12-20 | 2011-08-31 | 케모센트릭스 | 인간 종양-발현된 ccxckr2의 저해물질 |
NZ542866A (en) | 2003-04-23 | 2009-07-31 | Medarex Inc | Compositions and methods for the therapy of inflammatory bowel disease |
US20100247540A1 (en) * | 2003-10-30 | 2010-09-30 | Chemocentryx, Inc. | Methods and Compositions For Modulating Angiogenesis |
CA2563334A1 (en) * | 2004-04-16 | 2005-11-17 | Genentech, Inc. | Assay for antibodies |
CN102863532A (zh) | 2004-06-21 | 2013-01-09 | 米德列斯公司 | 干扰素α受体1抗体及其用途 |
PL1871804T3 (pl) * | 2005-04-21 | 2014-01-31 | Chemocentryx Inc | Przeciwciała wiążące CCX-CKR2 |
US9535071B2 (en) | 2012-09-07 | 2017-01-03 | The Governors Of The University Of Alberta | Methods and compositions for diagnosis of inflammatory liver disease |
EP2876114A1 (de) | 2013-11-25 | 2015-05-27 | Consejo Superior De Investigaciones Científicas | Antikörper gegen CCR9 und Anwendungen davon |
CN105685090B (zh) * | 2014-11-27 | 2018-02-13 | 山东棉花研究中心 | 一种防治棉花苗病的杀菌剂组合物 |
US20190054110A1 (en) | 2016-02-16 | 2019-02-21 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Modulators of ccr9 for treating tumor resistance to immune responses |
EP3416640A1 (de) | 2016-02-16 | 2018-12-26 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Modulatoren der tumorimmunresistenz zur behandlung von krebs |
EP4252629A3 (de) | 2016-12-07 | 2023-12-27 | Biora Therapeutics, Inc. | Verfahren, vorrichtungen und systeme zur detektion des magen-darm-trakts |
CA3045310A1 (en) | 2016-12-14 | 2018-06-21 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor |
KR20210095165A (ko) | 2018-11-19 | 2021-07-30 | 프로제너티, 인크. | 바이오의약품으로 질환을 치료하기 위한 방법 및 디바이스 |
CN115666704A (zh) | 2019-12-13 | 2023-01-31 | 比奥拉治疗股份有限公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
WO2023148346A1 (en) | 2022-02-03 | 2023-08-10 | Sunrock Biopharma S.L | Combination therapy comprising anti-ccr9 antibody and vincristine for cancer |
JP7368678B1 (ja) * | 2023-04-26 | 2023-10-25 | イミュニティリサーチ株式会社 | Cd4+t細胞集団中の特定の細胞亜集団の相対量の測定方法 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
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US18167A (en) * | 1857-09-08 | Improvement in blast-furnaces | ||
US5440021A (en) * | 1991-03-29 | 1995-08-08 | Chuntharapai; Anan | Antibodies to human IL-8 type B receptor |
US5652133A (en) | 1993-01-28 | 1997-07-29 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Cloning and expression of the human macrophage inflammatory protein-1.alpha.α) /rantes receptor |
EP2034023A1 (de) * | 1996-03-01 | 2009-03-11 | Euroscreen S.A. | CC-Chemokinzeptor C-C CKR-5, dessen Derivate und Verwendungen |
JP2000515733A (ja) | 1996-06-17 | 2000-11-28 | ヒューマン・ジェノム・サイエンシズ・インコーポレイテッド | ケモカインβ―15 |
US5981231A (en) | 1996-06-17 | 1999-11-09 | Human Genome Sciences, Inc. | Polynucleotides encoding chemokine β-15 |
US6723520B2 (en) * | 1996-07-05 | 2004-04-20 | Schering Corporation | Antibodies that bind chemokine teck |
WO1998001557A2 (en) | 1996-07-05 | 1998-01-15 | Schering Corporation | Mammalian chemokine reagents |
WO1998011218A1 (en) * | 1996-09-10 | 1998-03-19 | Theodor-Kocher Institute | Cxcr3 chemokine receptor, antibodies, nucleic acids, and methods of use |
WO1998032858A2 (en) | 1997-01-23 | 1998-07-30 | Schering Corporation | Mammalian chemokines; receptors; reagents; uses |
EP0878542A3 (de) * | 1997-04-22 | 2000-04-19 | Smithkline Beecham Corporation | CDNS Klon HMTMF81 der für einen neuen menschlichen 7-Transmembranrezeptor kodiert |
EP1019502A2 (de) * | 1997-08-06 | 2000-07-19 | Regeneron Pharmaceuticals, Inc. | Humane waisenrezeptor ntr-1 |
US6329159B1 (en) | 1999-03-11 | 2001-12-11 | Millennium Pharmaceuticals, Inc. | Anti-GPR-9-6 antibodies and methods of identifying agents which modulate GPR-9-6 function |
YU78601A (sh) * | 1999-05-05 | 2005-07-19 | Aventis Pharma Deutschland Gmbh. | 1-(p-tienilbenzil)-imidazoli kao agonisti angiotenzin-(1-7)- receptora, postupak za njihovu proizvodnju, njihova primena i farmaceutski preparati koji ih sadrže |
EP1248653A2 (de) * | 2000-01-07 | 2002-10-16 | Stichting Klinische Farmacologie Groningen | Gentherapie zur förderung von angiogenese sowie zur behandlung von herzinsuffienz |
DK1798223T4 (da) | 2002-11-18 | 2014-09-22 | Chemocentryx Inc | Arylsulfonamider |
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1999
- 1999-03-11 US US09/266,464 patent/US6329159B1/en not_active Expired - Lifetime
-
2000
- 2000-03-10 CA CA2365230A patent/CA2365230C/en not_active Expired - Lifetime
- 2000-03-10 EP EP00913864.5A patent/EP1157043B2/de not_active Expired - Lifetime
- 2000-03-10 AT AT00913864T patent/ATE517123T1/de not_active IP Right Cessation
- 2000-03-10 US US09/522,752 patent/US6936248B1/en not_active Expired - Lifetime
- 2000-03-10 WO PCT/US2000/006240 patent/WO2000053635A1/en active IP Right Grant
- 2000-03-10 AU AU35226/00A patent/AU771603B2/en not_active Expired
- 2000-03-10 JP JP2000604070A patent/JP5112578B2/ja not_active Expired - Lifetime
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2001
- 2001-09-13 US US09/952,385 patent/US6689570B2/en not_active Expired - Lifetime
- 2001-09-28 US US09/966,755 patent/US6884574B2/en not_active Expired - Lifetime
- 2001-10-23 US US10/000,759 patent/US7485301B2/en not_active Expired - Lifetime
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2005
- 2005-04-19 US US11/109,349 patent/US7381412B2/en not_active Expired - Lifetime
-
2011
- 2011-08-17 JP JP2011178577A patent/JP5933204B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1157043B1 (de) | 2011-07-20 |
AU3522600A (en) | 2000-09-28 |
US6689570B2 (en) | 2004-02-10 |
US20050181501A1 (en) | 2005-08-18 |
US7381412B2 (en) | 2008-06-03 |
US6884574B2 (en) | 2005-04-26 |
US20020141991A1 (en) | 2002-10-03 |
WO2000053635A1 (en) | 2000-09-14 |
EP1157043B2 (de) | 2015-07-22 |
CA2365230A1 (en) | 2000-09-14 |
US20020119504A1 (en) | 2002-08-29 |
US6936248B1 (en) | 2005-08-30 |
JP5112578B2 (ja) | 2013-01-09 |
EP1157043A1 (de) | 2001-11-28 |
JP2012012402A (ja) | 2012-01-19 |
US6329159B1 (en) | 2001-12-11 |
AU771603B2 (en) | 2004-04-01 |
US7485301B2 (en) | 2009-02-03 |
US20030022238A1 (en) | 2003-01-30 |
JP5933204B2 (ja) | 2016-06-08 |
CA2365230C (en) | 2015-11-24 |
JP2002542157A (ja) | 2002-12-10 |
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