JP2011530607A5 - - Google Patents
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- Publication number
- JP2011530607A5 JP2011530607A5 JP2011523078A JP2011523078A JP2011530607A5 JP 2011530607 A5 JP2011530607 A5 JP 2011530607A5 JP 2011523078 A JP2011523078 A JP 2011523078A JP 2011523078 A JP2011523078 A JP 2011523078A JP 2011530607 A5 JP2011530607 A5 JP 2011530607A5
- Authority
- JP
- Japan
- Prior art keywords
- lower alkyl
- phenyl
- substituted
- amino
- pyrimidylaminobenzamide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8838208P | 2008-08-13 | 2008-08-13 | |
| US61/088,382 | 2008-08-13 | ||
| US16450109P | 2009-03-30 | 2009-03-30 | |
| US61/164,501 | 2009-03-30 | ||
| PCT/US2009/053358 WO2010019540A1 (en) | 2008-08-13 | 2009-08-11 | Treatment of pulmonary arterial hypertension |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011530607A JP2011530607A (ja) | 2011-12-22 |
| JP2011530607A5 true JP2011530607A5 (cg-RX-API-DMAC7.html) | 2012-09-27 |
Family
ID=41137217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011523078A Pending JP2011530607A (ja) | 2008-08-13 | 2009-08-11 | 肺動脈高血圧の治療 |
Country Status (16)
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2671029A1 (en) | 2009-06-30 | 2010-12-30 | James S. Baldassarre | Methods of treating term and near-term neonates having hypoxic respiratory failure associated with clinical or echocardiographic evidence of pulmonary hypertension |
| EP3007689B1 (en) | 2013-01-10 | 2018-03-07 | Pulmokine, Inc. | Non-selective kinase inhibitors |
| JP6799201B2 (ja) * | 2013-07-31 | 2020-12-16 | アヴァリン ファーマ インク． | エアロゾルチロシンキナーゼ阻害剤の化合物、及びその使用 |
| US9925184B2 (en) | 2013-10-11 | 2018-03-27 | Pulmokine, Inc. | Spray-dry formulations |
| AU2017348354B2 (en) | 2016-10-27 | 2023-06-15 | Pulmokine, Inc. | Combination therapy for treating pulmonary hypertension |
| CN110198718B (zh) | 2016-11-08 | 2023-01-10 | 里亚塔医药控股有限责任公司 | 使用甲基巴多索隆或其类似物治疗阿尔波特综合征的方法 |
| WO2019157337A1 (en) * | 2018-02-08 | 2019-08-15 | Pulmokine, Inc. | Formulations of kinase inhibitors and prostanoids |
| CN114514016A (zh) | 2019-05-16 | 2022-05-17 | 埃渃维特治疗学公司 | 伊马替尼调配物、制造和其用途 |
| US11464776B2 (en) | 2019-05-16 | 2022-10-11 | Aerovate Therapeutics, Inc. | Inhalable imatinib formulations, manufacture, and uses thereof |
| WO2021108303A1 (en) * | 2019-11-25 | 2021-06-03 | PHPrecisionMed, LLC | Pharmaceutical compositions for the treatment of pulmonary hypertension |
| AU2021339756A1 (en) * | 2020-09-11 | 2023-04-13 | Pulmosim Therapeutics Llc | Compositions and methods for treating or preventing pulmonary hypertension |
| JP2023550407A (ja) | 2020-11-17 | 2023-12-01 | ユナイテッド セラピューティクス コーポレイション | 肺高血圧向けの吸入式イマチニブ |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5521184A (en) * | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
| GB0215676D0 (en) * | 2002-07-05 | 2002-08-14 | Novartis Ag | Organic compounds |
| AU2003272007A1 (en) * | 2002-10-25 | 2004-05-13 | The Administrators Of The Tulane Educational Fund | Use of n-5-4-(4-methylpiperaziomethyl)-benzoylamido!-2-methylphenyl!-4-(3-pyridyl)2-pyridine-amine for the treatment of pulmonary hypertension |
| GB0325031D0 (en) * | 2003-10-27 | 2003-12-03 | Novartis Ag | Organic compounds |
| MX2007009135A (es) * | 2005-01-28 | 2007-09-06 | Novartis Ag | Uso de pirimidilaminobenzamidas para el tratamiento de enfermedades que responden a la modulacion de la actividad de la cinasa tie-2. |
| KR101519311B1 (ko) * | 2005-05-02 | 2015-05-11 | 노파르티스 아게 | 과호산구성 증후군을 위한 피리미딜아미노벤즈아미드 유도체 |
| CA2629132C (en) * | 2005-12-06 | 2014-05-27 | Novartis Ag | Pyrimidylaminobenzamide derivatives for the treatment of neurofibromatosis |
| US20100048539A1 (en) * | 2006-11-03 | 2010-02-25 | Irm Llc | Compounds and compositions as protein kinase inhibitors |
-
2009
- 2009-08-11 EP EP09791358A patent/EP2315592A1/en not_active Withdrawn
- 2009-08-11 WO PCT/US2009/053358 patent/WO2010019540A1/en not_active Ceased
- 2009-08-11 US US13/058,742 patent/US20110190313A1/en not_active Abandoned
- 2009-08-11 BR BRPI0917491A patent/BRPI0917491A2/pt not_active IP Right Cessation
- 2009-08-11 CN CN2009801314677A patent/CN102123711A/zh active Pending
- 2009-08-11 KR KR1020117005744A patent/KR20110053354A/ko not_active Withdrawn
- 2009-08-11 AU AU2009282104A patent/AU2009282104A1/en not_active Abandoned
- 2009-08-11 NZ NZ590839A patent/NZ590839A/xx not_active IP Right Cessation
- 2009-08-11 CA CA2732789A patent/CA2732789A1/en not_active Abandoned
- 2009-08-11 MX MX2011001668A patent/MX2011001668A/es not_active Application Discontinuation
- 2009-08-11 JP JP2011523078A patent/JP2011530607A/ja active Pending
- 2009-08-11 RU RU2011109078/04A patent/RU2011109078A/ru not_active Application Discontinuation
- 2009-08-12 TW TW098127172A patent/TW201010999A/zh unknown
-
2011
- 2011-01-27 IL IL210922A patent/IL210922A0/en unknown
- 2011-02-11 CL CL2011000295A patent/CL2011000295A1/es unknown
- 2011-03-07 MA MA33678A patent/MA32617B1/fr unknown
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