JP2011528551A5 - - Google Patents
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- JP2011528551A5 JP2011528551A5 JP2011518935A JP2011518935A JP2011528551A5 JP 2011528551 A5 JP2011528551 A5 JP 2011528551A5 JP 2011518935 A JP2011518935 A JP 2011518935A JP 2011518935 A JP2011518935 A JP 2011518935A JP 2011528551 A5 JP2011528551 A5 JP 2011528551A5
- Authority
- JP
- Japan
- Prior art keywords
- dab
- antigen
- seq
- disease
- polypeptide sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8207808P | 2008-07-18 | 2008-07-18 | |
| US61/082,078 | 2008-07-18 | ||
| US16212109P | 2009-03-20 | 2009-03-20 | |
| US61/162,121 | 2009-03-20 | ||
| PCT/US2009/050985 WO2010009391A1 (en) | 2008-07-18 | 2009-07-17 | Compositions monovalent for cd28 binding and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014261305A Division JP5876134B2 (ja) | 2008-07-18 | 2014-12-24 | Ｃｄ２８結合のための一価組成物および使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011528551A JP2011528551A (ja) | 2011-11-24 |
| JP2011528551A5 true JP2011528551A5 (https=) | 2012-08-30 |
| JP5675608B2 JP5675608B2 (ja) | 2015-02-25 |
Family
ID=41226147
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011518935A Expired - Fee Related JP5675608B2 (ja) | 2008-07-18 | 2009-07-17 | Ｃｄ２８結合のための一価組成物および使用方法 |
| JP2014261305A Expired - Fee Related JP5876134B2 (ja) | 2008-07-18 | 2014-12-24 | Ｃｄ２８結合のための一価組成物および使用方法 |
| JP2016009024A Expired - Fee Related JP6058833B2 (ja) | 2008-07-18 | 2016-01-20 | Ｃｄ２８結合のための一価組成物および使用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014261305A Expired - Fee Related JP5876134B2 (ja) | 2008-07-18 | 2014-12-24 | Ｃｄ２８結合のための一価組成物および使用方法 |
| JP2016009024A Expired - Fee Related JP6058833B2 (ja) | 2008-07-18 | 2016-01-20 | Ｃｄ２８結合のための一価組成物および使用方法 |
Country Status (29)
| Country | Link |
|---|---|
| US (6) | US8168759B2 (https=) |
| EP (2) | EP2321352B1 (https=) |
| JP (3) | JP5675608B2 (https=) |
| KR (2) | KR101660057B1 (https=) |
| CN (2) | CN105936648B (https=) |
| AR (1) | AR072571A1 (https=) |
| AU (1) | AU2009270726B2 (https=) |
| CA (1) | CA2731220C (https=) |
| CL (2) | CL2011000117A1 (https=) |
| CO (1) | CO6341641A2 (https=) |
| CY (1) | CY1121796T1 (https=) |
| DK (2) | DK2700651T3 (https=) |
| EA (1) | EA024585B1 (https=) |
| ES (2) | ES2730727T3 (https=) |
| HR (2) | HRP20160329T1 (https=) |
| HU (2) | HUE029982T2 (https=) |
| IL (2) | IL210413A (https=) |
| LT (1) | LT2700651T (https=) |
| ME (1) | ME02396B (https=) |
| MX (1) | MX2011000501A (https=) |
| NZ (1) | NZ590343A (https=) |
| PE (2) | PE20110385A1 (https=) |
| PL (2) | PL2700651T3 (https=) |
| PT (2) | PT2700651T (https=) |
| RS (2) | RS58904B1 (https=) |
| SI (2) | SI2321352T1 (https=) |
| SM (2) | SMT201900367T1 (https=) |
| TW (2) | TW201336510A (https=) |
| WO (1) | WO2010009391A1 (https=) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8188223B2 (en) | 2005-05-18 | 2012-05-29 | Ablynx N.V. | Serum albumin binding proteins |
| PE20110385A1 (es) | 2008-07-18 | 2011-06-22 | Bristol Myers Squibb Co | Anticuerpo de dominio (dab) que se une a cd28 y no reacciona en forma cruzada con ctla4 |
| US20110097339A1 (en) * | 2008-07-18 | 2011-04-28 | Domantis Limited | Compositions monovalent for CD28 binding and methods of use |
| JP5745432B2 (ja) * | 2009-02-25 | 2015-07-08 | ネクステラ アーエス | シグナル配列非依存性ｐＩＸファージディスプレイ |
| FR2951176A1 (fr) * | 2009-10-09 | 2011-04-15 | Tcl Pharma | Ligands monovalents du recepteur cd28 humain |
| EP2361935A1 (en) * | 2010-02-18 | 2011-08-31 | TcL Pharma | Anti-CD28 humanized antibodies |
| LT2536764T (lt) | 2010-02-18 | 2018-10-25 | Ose Immunotherapeutics | Anti-cd28 humanizuoti antikūnai |
| CA2799540A1 (en) | 2010-06-08 | 2011-12-15 | Genentech, Inc. | Cysteine engineered antibodies and conjugates |
| JP5768022B2 (ja) * | 2012-03-19 | 2015-08-26 | 株式会社東芝 | メモリコントローラ、記憶装置、誤り訂正装置および誤り訂正方法 |
| WO2014120916A1 (en) | 2013-02-01 | 2014-08-07 | Bristol-Myers Squibb Company | Pegylated domain antibodies monovalent for cd28 binding and methods of use |
| MX2016008498A (es) * | 2013-12-27 | 2016-10-07 | Chugai Pharmaceutical Co Ltd | Metodo para purificar anticuerpo que tiene bajo punto isoelectrico. |
| CN106132429A (zh) | 2014-03-19 | 2016-11-16 | 百时美施贵宝公司 | 使用针对cd40l的域抗体治疗移植物排斥的方法 |
| SG11201701128YA (en) | 2014-09-12 | 2017-03-30 | Genentech Inc | Cysteine engineered antibodies and conjugates |
| MX2017003691A (es) * | 2014-09-30 | 2017-06-26 | Bristol Myers Squibb Co | Metodos para tratar lupus eritematoso sistemico usando un anticuerpo de dominio dirigido contra cd28. |
| WO2017160975A1 (en) * | 2016-03-16 | 2017-09-21 | Bristol-Myers Squibb Company | Methods of diagnosing and treating lupus |
| WO2018106945A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| WO2018183929A1 (en) | 2017-03-30 | 2018-10-04 | Progenity Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| SG11201909160WA (en) | 2017-04-11 | 2019-10-30 | Inhibrx Inc | Multispecific polypeptide constructs having constrained cd3 binding and methods of using the same |
| AU2019234183B2 (en) | 2018-03-15 | 2025-12-18 | Biond Biologics Ltd. | Methods and compositions for decreasing soluble immune receptor CD28 |
| KR20260046525A (ko) | 2018-04-11 | 2026-04-07 | 인히브릭스 바이오사이언스, 인크. | 제한된 cd3 결합을 갖는 다중특이적 폴리펩티드 컨스트럭트 및 관련된 방법 및 용도 |
| KR20210035805A (ko) | 2018-06-15 | 2021-04-01 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | 세포후 신호전달 인자의 조절을 통한 면역 활성의 증가 |
| WO2019246317A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease or condition in a tissue originating from the endoderm |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| US12139537B2 (en) | 2018-06-22 | 2024-11-12 | Junten Bio Co., Ltd. | Antibody inducing immune tolerance, induced lymphocyte, and cell therapy agent therapeutic method using induced lymphocyte |
| EP3833685A4 (en) * | 2018-07-08 | 2022-08-17 | Specifica Inc. | ANTIBODY LIBRARIES WITH FEATURES FOR MAXIMIZED ANTIBODY DEVELOPMENT |
| EP3827019A1 (en) | 2018-07-24 | 2021-06-02 | Inhibrx, Inc. | Multispecific polypeptide constructs containing a constrained cd3 binding domain and a receptor binding region and methods of using the same |
| KR102718808B1 (ko) | 2018-08-03 | 2024-10-16 | 브리스톨-마이어스 스큅 컴퍼니 | 항-약물 항체를 검출하는 방법 |
| EP3883635A1 (en) | 2018-11-19 | 2021-09-29 | Progenity, Inc. | Methods and devices for treating a disease with biotherapeutics |
| EP3938397A1 (en) * | 2019-03-14 | 2022-01-19 | Biond Biologics Ltd. | Small shedding blocking agents |
| WO2020227159A2 (en) | 2019-05-03 | 2020-11-12 | Flagship Pioneering Innovations V, Inc. | Methods of modulating immune activity |
| ES2821599A1 (es) * | 2019-10-24 | 2021-04-26 | Univ Del Pais Vasco / Euskal Herriko Unibertsitatea | Compuestos y metodos para el tratamiento de la enfermedad de alzheimer |
| JP2023509803A (ja) * | 2019-12-02 | 2023-03-09 | ビオンド バイオロジクス リミテッド | Ｍｍｐ抑制の使用 |
| CN115666704B (zh) | 2019-12-13 | 2025-09-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| US20230114107A1 (en) | 2019-12-17 | 2023-04-13 | Flagship Pioneering Innovations V, Inc. | Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly |
| JP7789002B2 (ja) * | 2020-01-29 | 2025-12-19 | インヒブルクス バイオサイエンシズ インコーポレイテッド | Ｃｄ２８シングルドメイン抗体ならびにその多価および多重特異性の構築物 |
| CN115515982A (zh) | 2020-03-12 | 2022-12-23 | 比昂生物制剂公司 | 具有增加的稳定性的脱落阻断剂 |
| US20230355804A1 (en) | 2020-06-29 | 2023-11-09 | Flagship Pioneering Innovations V, Inc. | Viruses engineered to promote thanotransmission and their use in treating cancer |
| US20230303699A1 (en) * | 2020-08-04 | 2023-09-28 | Exelixis, Inc. | Pd-l1 binding agents and uses thereof |
| EP4313109A1 (en) | 2021-03-31 | 2024-02-07 | Flagship Pioneering Innovations V, Inc. | Thanotransmission polypeptides and their use in treating cancer |
| AU2022303363A1 (en) | 2021-06-29 | 2024-01-18 | Flagship Pioneering Innovations V, Inc. | Immune cells engineered to promote thanotransmission and uses thereof |
| EP4399229A2 (en) * | 2021-09-06 | 2024-07-17 | Biond Biologics Ltd. | Cd28 shedding blocking agents |
| CN119451993A (zh) * | 2022-05-04 | 2025-02-14 | 佳努克斯治疗公司 | 用于靶向cd28和pd-l1的肿瘤激活多特异性抗体及其使用方法 |
| WO2023215498A2 (en) * | 2022-05-05 | 2023-11-09 | Modernatx, Inc. | Compositions and methods for cd28 antagonism |
| WO2023215560A1 (en) | 2022-05-05 | 2023-11-09 | Atoosa Corporation | Tumor cell/immune cell multivalent receptor engager – bio-nanoparticle (timre-bnp) |
| WO2024040194A1 (en) | 2022-08-17 | 2024-02-22 | Capstan Therapeutics, Inc. | Conditioning for in vivo immune cell engineering |
| US20240174732A1 (en) | 2022-10-05 | 2024-05-30 | Flagship Pioneering Innovations V, Inc. | Nucleic acid molecules encoding trif and additional polypeptides and their use in treating cancer |
| US20240228620A1 (en) | 2022-10-06 | 2024-07-11 | Bicara Therapeutics Inc. | Multispecific proteins and related methods |
| WO2024151687A1 (en) | 2023-01-09 | 2024-07-18 | Flagship Pioneering Innovations V, Inc. | Genetic switches and their use in treating cancer |
| WO2024211211A1 (en) | 2023-04-03 | 2024-10-10 | Regeneron Pharmaceuticals, Inc. | Methods of improving transplant survival using il-2 receptor gamma chain antibodies |
| AU2024279278A1 (en) | 2023-05-31 | 2025-12-18 | Capstan Therapeutics, Inc. | Lipid nanoparticle formulations and compositions |
| WO2025076113A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Ionizable cationic lipids with conserved spacing and lipid nanoparticles |
| US20250127728A1 (en) | 2023-10-05 | 2025-04-24 | Capstan Therapeutics, Inc. | Constrained Ionizable Cationic Lipids and Lipid Nanoparticles |
| US20250302763A1 (en) | 2024-02-22 | 2025-10-02 | Capstan Therapeutics, Inc. | Immune engineering amplification |
| WO2025217452A1 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
| WO2025217454A2 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Ionizable cationic lipids and lipid nanoparticles |
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| PT1419179E (pt) | 2001-08-10 | 2010-03-16 | Univ Aberdeen | Domínios de ligação de antigenes |
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| JP2005289809A (ja) | 2001-10-24 | 2005-10-20 | Vlaams Interuniversitair Inst Voor Biotechnologie Vzw (Vib Vzw) | 突然変異重鎖抗体 |
| DE10156482A1 (de) * | 2001-11-12 | 2003-05-28 | Gundram Jung | Bispezifisches Antikörper-Molekül |
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| EP1578801A2 (en) | 2002-12-27 | 2005-09-28 | Domantis Limited | Dual specific single domain antibodies specific for a ligand and for the receptor of the ligand |
| JP2008501621A (ja) | 2003-05-31 | 2008-01-24 | マイクロメット アクツィエン ゲゼルシャフト | Ｂ細胞関連疾患を処置するための二重特異性抗ｃｄ３、抗ｃｄ１９抗体構築物を含む薬学的組成物 |
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| CN100376599C (zh) * | 2004-04-01 | 2008-03-26 | 北京安波特基因工程技术有限公司 | 基因工程重组抗cea抗cd3抗cd28线性单链三特异抗体 |
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| MX2011001624A (es) | 2008-08-21 | 2011-03-28 | Octapharma Ag | Factor viii y ix humano producido en forma recombinante. |
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| MX2017003691A (es) * | 2014-09-30 | 2017-06-26 | Bristol Myers Squibb Co | Metodos para tratar lupus eritematoso sistemico usando un anticuerpo de dominio dirigido contra cd28. |
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2009
- 2009-07-17 PE PE2011000053A patent/PE20110385A1/es active IP Right Grant
- 2009-07-17 ES ES13185422T patent/ES2730727T3/es active Active
- 2009-07-17 HU HUE09790582A patent/HUE029982T2/en unknown
- 2009-07-17 SI SI200931383T patent/SI2321352T1/sl unknown
- 2009-07-17 DK DK13185422.6T patent/DK2700651T3/da active
- 2009-07-17 LT LTEP13185422.6T patent/LT2700651T/lt unknown
- 2009-07-17 RS RS20190631A patent/RS58904B1/sr unknown
- 2009-07-17 DK DK09790582.2T patent/DK2321352T3/en active
- 2009-07-17 SM SM20190367T patent/SMT201900367T1/it unknown
- 2009-07-17 EP EP09790582.2A patent/EP2321352B1/en active Active
- 2009-07-17 PT PT13185422T patent/PT2700651T/pt unknown
- 2009-07-17 PE PE2014000192A patent/PE20140852A1/es not_active Application Discontinuation
- 2009-07-17 WO PCT/US2009/050985 patent/WO2010009391A1/en not_active Ceased
- 2009-07-17 EA EA201100239A patent/EA024585B1/ru not_active IP Right Cessation
- 2009-07-17 EP EP13185422.6A patent/EP2700651B1/en active Active
- 2009-07-17 CN CN201610344002.1A patent/CN105936648B/zh active Active
- 2009-07-17 KR KR1020117003660A patent/KR101660057B1/ko active Active
- 2009-07-17 HU HUE13185422A patent/HUE045249T2/hu unknown
- 2009-07-17 CA CA2731220A patent/CA2731220C/en not_active Expired - Fee Related
- 2009-07-17 MX MX2011000501A patent/MX2011000501A/es active IP Right Grant
- 2009-07-17 HR HRP20160329TT patent/HRP20160329T1/hr unknown
- 2009-07-17 RS RS20160200A patent/RS54675B1/sr unknown
- 2009-07-17 ES ES09790582.2T patent/ES2562629T3/es active Active
- 2009-07-17 TW TW101147598A patent/TW201336510A/zh unknown
- 2009-07-17 AU AU2009270726A patent/AU2009270726B2/en not_active Ceased
- 2009-07-17 ME MEP-2016-76A patent/ME02396B/me unknown
- 2009-07-17 AR ARP090102734A patent/AR072571A1/es active IP Right Grant
- 2009-07-17 PT PT97905822T patent/PT2321352E/pt unknown
- 2009-07-17 NZ NZ590343A patent/NZ590343A/xx unknown
- 2009-07-17 JP JP2011518935A patent/JP5675608B2/ja not_active Expired - Fee Related
- 2009-07-17 PL PL13185422T patent/PL2700651T3/pl unknown
- 2009-07-17 SI SI200931964T patent/SI2700651T1/sl unknown
- 2009-07-17 TW TW098124305A patent/TWI450725B/zh not_active IP Right Cessation
- 2009-07-17 CN CN2009801358711A patent/CN102159590A/zh active Pending
- 2009-07-17 US US12/505,166 patent/US8168759B2/en active Active
- 2009-07-17 PL PL09790582T patent/PL2321352T3/pl unknown
- 2009-07-17 KR KR1020167025702A patent/KR101791372B1/ko not_active Expired - Fee Related
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2010
- 2010-12-30 IL IL210413A patent/IL210413A/en active IP Right Grant
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2011
- 2011-01-18 CL CL2011000117A patent/CL2011000117A1/es unknown
- 2011-02-15 CO CO11017973A patent/CO6341641A2/es active IP Right Grant
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2012
- 2012-03-09 US US13/416,033 patent/US8454959B2/en not_active Expired - Fee Related
- 2012-03-09 US US13/415,914 patent/US9085629B2/en active Active
- 2012-08-31 CL CL2012002428A patent/CL2012002428A1/es unknown
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2014
- 2014-12-24 JP JP2014261305A patent/JP5876134B2/ja not_active Expired - Fee Related
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2015
- 2015-06-16 US US14/740,709 patent/US9908937B2/en not_active Expired - Fee Related
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2016
- 2016-01-20 JP JP2016009024A patent/JP6058833B2/ja not_active Expired - Fee Related
- 2016-03-29 SM SM201600090T patent/SMT201600090B/xx unknown
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2017
- 2017-03-21 IL IL251320A patent/IL251320B/en active IP Right Grant
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2018
- 2018-01-12 US US15/870,121 patent/US10919965B2/en active Active
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2019
- 2019-05-28 HR HRP20190966TT patent/HRP20190966T1/hr unknown
- 2019-07-09 CY CY20191100722T patent/CY1121796T1/el unknown
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2020
- 2020-11-02 US US17/086,565 patent/US12012452B2/en active Active
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