JP2011528356A - 殺生物組成物及び方法 - Google Patents
殺生物組成物及び方法 Download PDFInfo
- Publication number
- JP2011528356A JP2011528356A JP2011518815A JP2011518815A JP2011528356A JP 2011528356 A JP2011528356 A JP 2011528356A JP 2011518815 A JP2011518815 A JP 2011518815A JP 2011518815 A JP2011518815 A JP 2011518815A JP 2011528356 A JP2011528356 A JP 2011528356A
- Authority
- JP
- Japan
- Prior art keywords
- aqueous medium
- alkaline aqueous
- bnpd
- nitrilopropionamide
- dibromo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/34—Nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/524—Preservatives
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Plant Pathology (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Pest Control & Pesticides (AREA)
- Dermatology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Detergent Compositions (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Paints Or Removers (AREA)
- Treatment And Processing Of Natural Fur Or Leather (AREA)
Abstract
Description
相乗作用指数=CA/Ca+CB/Cb (1)
[式中、Ca=所定の終点を生じる抗菌剤A単独の濃度
Cb=所定の終点を生じる抗菌剤B単独の濃度
CA及びCB=所定の終点を生じる、混合物中に一緒に含まれる抗菌剤A及びBのそれぞれの濃度]
予想通り、DBNPAは単独では、140ppmの活性物質濃度で、初回接種から1時間後においてラテックスの除染に効果がある。BNPDは、試験した最高活性物質濃度(600ppm)でも、1時間以内に細菌濃度の4log10の低下を達成しなかった。活性物質濃度120ppmのDBNPAと活性物質濃度35ppmのBNPDの組合せは、この時点でサンプルを効果的に除染し、0.92未満の相乗作用指数を達成した。この組合せの真価、及び全く予想外の結果は、3日間貯蔵後の時点で2回目接種を行った後の作用であった。この2回目接種の4時間後においては、個々の活性物質の最高試験濃度で除染は達成されなかったが、177.5ppmのDBNPAと59.2ppmのBNPDとの組合せでは効果があった(SI<0.54)。この2回目接種の24時間後においては、BNPD(活性物質95.7ppm)は効果があることがわかった。しかし、この組合せは、これら2種の活性物質が極めて低濃度であっても効果があった(SI=0.29)。更に意外なことに、初回接種の7日後に2回目接種を行った場合には、これら2種の活性物質の比較的低濃度での組合せ(DBNPA 80.9ppm及びBNPD 27ppm)により、24時間で除染が達成された。DBNPAそれ自身では最高試験濃度でも除染を達成しないが、単独で使用する場合、95.7ppmのBNPDを必要とする。このデータに基づいて、0.48の相乗作用指数が算出された。一般的な知識からはこれら2種の活性物質は、このより遅い時点で非活性化されることが予測されるので、これは全く予想外である。
Claims (11)
- 2,2−ジブロモ−3−ニトリロプロピオンアミド及び2−ブロモ−2−ニトロ−1,3−プロパンジオールを含む殺生物混合物の有効量をアルカリ水性媒体中に含ませることを含んでなる、迅速除染及び長期保存の両方を必要とするアルカリ水性媒体中における微生物の増殖を抑制する方法。
- 2,2−ジブロモ−3−ニトリロプロピオンアミド対2−ブロモ−2−ニトロ−1,3−プロパンジオールの重量比が約100:1〜約1:100である請求項1に記載の方法。
- 前記2,2−ジブロモ−3−ニトリロプロピオンアミド及び前記2−ブロモ−2−ニトロ−1,3−プロパンジオールを、前記水性媒体の総重量に基づき、約100〜約4000ppmの総初期濃度で、水性媒体中に、含ませる請求項1〜2に記載の方法。
- 前記アルカリ水性媒体が7.5又はそれ以上のpHを有する請求項1〜3に記載の方法。
- 前記アルカリ水性媒体が、完成品の製造において、そしてペイント及びコーティング、ラテックス、ミネラルスラリー、接着剤、洗浄剤、クリーナー、クリーニングワイプ、カーケア製品の装置及びタンク洗浄、並びにこれらの製品用の原料、オイル及びガスの探査、破砕流体保存、革なめし及びパーソナルケア製品において、使用される原料、完成品及びプロセス/洗浄水である請求項1〜4に記載の方法。
- 長期保存及び迅速除染の両方を必要とするアルカリ水性媒体を、1週間の間に1回だけ前記殺生物混合物によって、処理する請求項1〜5に記載の方法。
- 前記水性媒体が15ppm未満のCMIT/MITを含む請求項1〜6に記載の方法。
- 前記水性媒体を、前記殺生物ブレンドの組入れ後に1回又はそれ以上の微生物侵襲によって接種させる請求項1〜7に記載の方法。
- 1回又はそれ以上の追加の微生物侵襲が、前記水性媒体への前記殺生剤ブレンドの組入れの3日後又はそれ以降に起こる請求項8に記載の方法。
- 2,2−ジブロモ−3−ニトリロプロピオンアミド(DBNPA);
2−ブロモ−2−ニトロ−1,3−プロパンジオール(BNPD);及び
アルカリ水性媒体
を含んでなる、微生物の増殖を抑制する組成物。 - CMIT/MITを含まない請求項10に記載の組成物。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8082808P | 2008-07-15 | 2008-07-15 | |
US61/080,828 | 2008-07-15 | ||
PCT/US2009/050372 WO2010009033A2 (en) | 2008-07-15 | 2009-07-13 | Biocidal composition and method |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014257595A Division JP2015096537A (ja) | 2008-07-15 | 2014-12-19 | 殺生物組成物及び方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2011528356A true JP2011528356A (ja) | 2011-11-17 |
Family
ID=41530856
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2011518815A Pending JP2011528356A (ja) | 2008-07-15 | 2009-07-13 | 殺生物組成物及び方法 |
JP2014257595A Pending JP2015096537A (ja) | 2008-07-15 | 2014-12-19 | 殺生物組成物及び方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2014257595A Pending JP2015096537A (ja) | 2008-07-15 | 2014-12-19 | 殺生物組成物及び方法 |
Country Status (10)
Country | Link |
---|---|
US (1) | US20100016441A1 (ja) |
EP (1) | EP2306822B1 (ja) |
JP (2) | JP2011528356A (ja) |
KR (1) | KR101657723B1 (ja) |
CN (2) | CN102159074A (ja) |
AU (1) | AU2009271167B2 (ja) |
BR (1) | BRPI0910359A2 (ja) |
MX (1) | MX2011000621A (ja) |
RU (1) | RU2513136C2 (ja) |
WO (1) | WO2010009033A2 (ja) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2432740B1 (en) * | 2009-05-18 | 2017-02-22 | Dow Global Technologies LLC | Controlling bacteria with brominated amide biocidal compounds in a water system at pH higher than 6 as well as new brominated compound |
WO2010135195A1 (en) * | 2009-05-18 | 2010-11-25 | Dow Global Technologies Inc. | Controlling biofilm with halogenated amides as biocides |
BRPI1007575B1 (pt) * | 2009-05-18 | 2019-10-15 | Dow Global Technologies Llc | Método para controlar micro-organismos em um sistema aquoso |
WO2012044301A1 (en) * | 2010-09-30 | 2012-04-05 | Dow Global Technologies Llc | Compositions of dibromomalonamide and their use as biocides |
CN102794112B (zh) * | 2012-09-03 | 2015-09-16 | 常州精科霞峰精细化工有限公司 | 反渗透膜用杀菌剂及其制备方法 |
CN102894001A (zh) * | 2012-10-19 | 2013-01-30 | 陕西省石油化工研究设计院 | 一种湿巾用防腐防霉剂组合物及其生产方法 |
CN102960343B (zh) * | 2012-11-27 | 2014-06-11 | 中国石油天然气集团公司 | 一种高浓防腐杀菌剂 |
WO2016134998A1 (en) * | 2015-02-27 | 2016-09-01 | Sabic Global Technologies B.V. | Methods for improving the base color of plastic by reducing biological growth in the latex system |
CN105132210A (zh) * | 2015-09-02 | 2015-12-09 | 西安热工研究院有限公司 | 一种保安过滤器滤芯的清洗配方 |
EP3860346A1 (en) * | 2018-10-04 | 2021-08-11 | Celanese International Corporation | Process for producing aqueous coating compositions |
FR3110173B1 (fr) * | 2020-05-14 | 2022-06-17 | Ifp Energies Now | Procédé de traitement d’une formation souterraine comprenant des micro-organismes |
CN112868650A (zh) * | 2021-02-03 | 2021-06-01 | 山东华特水处理科技有限公司 | 一种杀菌剂及其制备方法和应用 |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS60231603A (ja) * | 1984-04-28 | 1985-11-18 | Somar Corp | 防菌剤 |
US4732913A (en) * | 1987-02-25 | 1988-03-22 | Betz Laboratories, Inc. | Biocidal compositions and use thereof containing a synergistic mixture of 2-bromo-2-nitropropane-1,3-diol and 2,2-dibromo-3-nitrilopropionamide |
JPH08231320A (ja) * | 1994-12-28 | 1996-09-10 | Katayama Chem Works Co Ltd | 工業用殺菌剤及び工業用殺菌方法 |
JPH11322510A (ja) * | 1998-05-12 | 1999-11-24 | Kurita Water Ind Ltd | 工業用抗菌剤組成物及び抗菌方法 |
JP2000063211A (ja) * | 1998-08-19 | 2000-02-29 | Shintoo Fine Kk | 工業用抗菌剤組成物および抗菌方法 |
JP2000319113A (ja) * | 1999-05-10 | 2000-11-21 | Somar Corp | 有害微生物撲滅剤 |
JP2001288016A (ja) * | 2000-03-31 | 2001-10-16 | Katayama Chem Works Co Ltd | 工業用抗菌剤およびそれを用いた工業的抗菌方法 |
JP2001302414A (ja) * | 2000-04-21 | 2001-10-31 | Kurita Water Ind Ltd | 工業用抗菌剤組成物及び抗菌方法 |
JP2002003311A (ja) * | 2000-06-23 | 2002-01-09 | Katayama Chem Works Co Ltd | 抗菌剤およびそれを用いた抗菌方法 |
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EP0912097B1 (en) * | 1996-05-09 | 2002-08-07 | Novozymes A/S | Antimicrobial peroxidase compositions |
DE10040814A1 (de) * | 2000-08-21 | 2002-03-07 | Thor Gmbh | Synergistische Biozidzusammensetzung |
DE10042894A1 (de) | 2000-08-31 | 2002-03-14 | Thor Chemie Gmbh | Synergistische Biozidzusammensetzung mit 2-Methylisothiazolin-3-on |
GB2374011C (en) * | 2001-01-04 | 2008-02-06 | Byotrol Llc | Anti-microbial composition |
JP4637464B2 (ja) * | 2003-07-01 | 2011-02-23 | Jsr株式会社 | 化学機械研磨用水系分散体 |
JP4026829B2 (ja) | 2003-07-24 | 2007-12-26 | ローム アンド ハース カンパニー | 殺微生物組成物 |
CN100496250C (zh) * | 2007-08-17 | 2009-06-10 | 王安林 | 一种农用消毒杀菌组合物、它们的制备方法与用途 |
-
2009
- 2009-07-13 AU AU2009271167A patent/AU2009271167B2/en not_active Ceased
- 2009-07-13 CN CN2009801272640A patent/CN102159074A/zh active Pending
- 2009-07-13 US US12/501,707 patent/US20100016441A1/en not_active Abandoned
- 2009-07-13 JP JP2011518815A patent/JP2011528356A/ja active Pending
- 2009-07-13 CN CN201410393095.8A patent/CN104145955A/zh active Pending
- 2009-07-13 BR BRPI0910359A patent/BRPI0910359A2/pt not_active Application Discontinuation
- 2009-07-13 EP EP09790327.2A patent/EP2306822B1/en not_active Revoked
- 2009-07-13 KR KR1020117003355A patent/KR101657723B1/ko active IP Right Grant
- 2009-07-13 WO PCT/US2009/050372 patent/WO2010009033A2/en active Application Filing
- 2009-07-13 RU RU2011105400/13A patent/RU2513136C2/ru not_active IP Right Cessation
- 2009-07-13 MX MX2011000621A patent/MX2011000621A/es not_active Application Discontinuation
-
2014
- 2014-12-19 JP JP2014257595A patent/JP2015096537A/ja active Pending
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
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JPS60231603A (ja) * | 1984-04-28 | 1985-11-18 | Somar Corp | 防菌剤 |
US4732913A (en) * | 1987-02-25 | 1988-03-22 | Betz Laboratories, Inc. | Biocidal compositions and use thereof containing a synergistic mixture of 2-bromo-2-nitropropane-1,3-diol and 2,2-dibromo-3-nitrilopropionamide |
JPH08231320A (ja) * | 1994-12-28 | 1996-09-10 | Katayama Chem Works Co Ltd | 工業用殺菌剤及び工業用殺菌方法 |
JPH11322510A (ja) * | 1998-05-12 | 1999-11-24 | Kurita Water Ind Ltd | 工業用抗菌剤組成物及び抗菌方法 |
JP2000063211A (ja) * | 1998-08-19 | 2000-02-29 | Shintoo Fine Kk | 工業用抗菌剤組成物および抗菌方法 |
JP2000319113A (ja) * | 1999-05-10 | 2000-11-21 | Somar Corp | 有害微生物撲滅剤 |
JP2001288016A (ja) * | 2000-03-31 | 2001-10-16 | Katayama Chem Works Co Ltd | 工業用抗菌剤およびそれを用いた工業的抗菌方法 |
JP2001302414A (ja) * | 2000-04-21 | 2001-10-31 | Kurita Water Ind Ltd | 工業用抗菌剤組成物及び抗菌方法 |
JP2002003311A (ja) * | 2000-06-23 | 2002-01-09 | Katayama Chem Works Co Ltd | 抗菌剤およびそれを用いた抗菌方法 |
Also Published As
Publication number | Publication date |
---|---|
CN102159074A (zh) | 2011-08-17 |
RU2513136C2 (ru) | 2014-04-20 |
AU2009271167A1 (en) | 2010-01-21 |
WO2010009033A3 (en) | 2010-09-10 |
EP2306822B1 (en) | 2016-10-26 |
KR101657723B1 (ko) | 2016-09-19 |
MX2011000621A (es) | 2011-02-25 |
JP2015096537A (ja) | 2015-05-21 |
CN104145955A (zh) | 2014-11-19 |
AU2009271167B2 (en) | 2015-05-14 |
EP2306822A2 (en) | 2011-04-13 |
KR20110034015A (ko) | 2011-04-04 |
RU2011105400A (ru) | 2012-08-20 |
US20100016441A1 (en) | 2010-01-21 |
WO2010009033A2 (en) | 2010-01-21 |
BRPI0910359A2 (pt) | 2015-09-22 |
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