JP2011524339A5 - - Google Patents
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- Publication number
- JP2011524339A5 JP2011524339A5 JP2011509678A JP2011509678A JP2011524339A5 JP 2011524339 A5 JP2011524339 A5 JP 2011524339A5 JP 2011509678 A JP2011509678 A JP 2011509678A JP 2011509678 A JP2011509678 A JP 2011509678A JP 2011524339 A5 JP2011524339 A5 JP 2011524339A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- cell
- cancer
- cancer cell
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000427 antigen Substances 0.000 description 6
- 102000036639 antigens Human genes 0.000 description 6
- 108091007433 antigens Proteins 0.000 description 6
- 206010028980 Neoplasm Diseases 0.000 description 5
- 201000011510 cancer Diseases 0.000 description 5
- 230000002238 attenuated effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5394708P | 2008-05-16 | 2008-05-16 | |
| US61/053,947 | 2008-05-16 | ||
| PCT/US2009/043874 WO2009140447A1 (en) | 2008-05-16 | 2009-05-14 | Immunomodulation by iap inhibitors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015040113A Division JP5986655B2 (ja) | 2008-05-16 | 2015-03-02 | Ｉａｐ阻害剤による免疫調節 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011524339A JP2011524339A (ja) | 2011-09-01 |
| JP2011524339A5 true JP2011524339A5 (enExample) | 2014-04-24 |
| JP5779091B2 JP5779091B2 (ja) | 2015-09-16 |
Family
ID=40823320
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011509678A Active JP5779091B2 (ja) | 2008-05-16 | 2009-05-14 | Ｉａｐ阻害剤による免疫調節 |
| JP2015040113A Active JP5986655B2 (ja) | 2008-05-16 | 2015-03-02 | Ｉａｐ阻害剤による免疫調節 |
| JP2015236482A Active JP6030739B2 (ja) | 2008-05-16 | 2015-12-03 | Ｉａｐ阻害剤による免疫調節 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015040113A Active JP5986655B2 (ja) | 2008-05-16 | 2015-03-02 | Ｉａｐ阻害剤による免疫調節 |
| JP2015236482A Active JP6030739B2 (ja) | 2008-05-16 | 2015-12-03 | Ｉａｐ阻害剤による免疫調節 |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US9750729B2 (enExample) |
| EP (3) | EP2296650B1 (enExample) |
| JP (3) | JP5779091B2 (enExample) |
| KR (1) | KR20110022608A (enExample) |
| CN (1) | CN102099035A (enExample) |
| AU (1) | AU2009246347A1 (enExample) |
| BR (1) | BRPI0912692A2 (enExample) |
| CA (1) | CA2724720A1 (enExample) |
| CL (1) | CL2009001195A1 (enExample) |
| EA (1) | EA201071316A1 (enExample) |
| ES (2) | ES2882855T3 (enExample) |
| IL (1) | IL209203A0 (enExample) |
| MA (1) | MA32388B1 (enExample) |
| MX (1) | MX2010012231A (enExample) |
| TW (1) | TW201006834A (enExample) |
| WO (1) | WO2009140447A1 (enExample) |
| ZA (1) | ZA201008176B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006122408A1 (en) | 2005-05-18 | 2006-11-23 | Aegera Therapeutics Inc. | Bir domain binding compounds |
| AU2006308453B9 (en) | 2005-10-25 | 2011-12-01 | Pharmascience Inc. | IAP BIR domain binding compounds |
| EP2296650B1 (en) * | 2008-05-16 | 2020-05-06 | Novartis AG | Immunomodulation by iap inhibitors |
| JP4995211B2 (ja) * | 2008-09-29 | 2012-08-08 | キヤノン株式会社 | 電子写真画像形成装置 |
| NZ602368A (en) | 2010-02-12 | 2014-10-31 | Pharmascience Inc | Iap bir domain binding compounds |
| KR20160030099A (ko) * | 2013-06-25 | 2016-03-16 | 더 월터 앤드 엘리자 홀 인스티튜트 오브 메디컬 리서치 | 세포내 감염의 치료 방법 |
| WO2015109391A1 (en) | 2014-01-24 | 2015-07-30 | Children's Hospital Of Eastern Ontario Research Institute Inc. | Smc combination therapy for the treatment of cancer |
| AU2017253560B2 (en) * | 2016-04-20 | 2019-03-21 | Glaxosmithkline Intellectual Property Development Limited | Conjugates comprising RIPK2 inhibitors |
| CN106496213B (zh) * | 2016-09-30 | 2019-08-20 | 东南大学 | Lcl161前药及其制备方法和应用 |
| WO2020027225A1 (ja) * | 2018-07-31 | 2020-02-06 | ファイメクス株式会社 | 複素環化合物 |
| JP2022511437A (ja) | 2018-11-26 | 2022-01-31 | デバイオファーム インターナショナル エス．エー． | Ｈｉｖ感染の組み合わせ治療 |
| AU2020356356A1 (en) | 2019-09-25 | 2022-05-12 | Debiopharm International S.A. | Dosing regimens for treatment of patients with locally advanced squamous cell carcinoma |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2610934B1 (fr) * | 1987-02-13 | 1989-05-05 | Adir | Nouveaux derives peptidiques a structure polycyclique azotee, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US6133437A (en) * | 1997-02-13 | 2000-10-17 | Apoptogen, Inc. | Modulation of IAPs for the treatment of proliferative diseases |
| ES2415336T3 (es) * | 2003-04-11 | 2013-07-25 | Survac Aps | Vacuna terapéutica contra el cáncer |
| EP1711515A2 (en) | 2004-02-04 | 2006-10-18 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases, particularly hcv ns3-ns4a protease |
| EP1723122B1 (en) * | 2004-03-01 | 2014-11-19 | Board of Regents, The University of Texas System | Dimeric small molecule potentiators of apoptosis |
| US7345081B2 (en) | 2004-03-23 | 2008-03-18 | Genentech, Inc. | Azabicyclo-octane inhibitors of IAP |
| PL2253614T3 (pl) * | 2004-04-07 | 2013-03-29 | Novartis Ag | Inhibitory IAP |
| EP1749558A4 (en) | 2004-05-02 | 2008-03-12 | Sega Corp | GAME SYSTEM |
| EA012810B1 (ru) | 2005-02-25 | 2009-12-30 | Тетралоджик Фармасеутикалс | Димерные ингибиторы ингибиторов белков апоптоза (iap) |
| US20090005411A1 (en) | 2005-12-20 | 2009-01-01 | Novartic Ag | Combinations of Organic Compounds |
| US20100056495A1 (en) * | 2006-07-24 | 2010-03-04 | Tetralogic Pharmaceuticals Corporation | Dimeric iap inhibitors |
| PE20110217A1 (es) | 2006-08-02 | 2011-04-01 | Novartis Ag | DERIVADOS DE 2-OXO-ETIL-AMINO-PROPIONAMIDA-PIRROLIDIN-2-IL-SUSTITUIDOS COMO INHIBIDORES DEL ENLACE DE LA PROTEINA Smac AL INHIBIDOR DE LA PROTEINA DE APOPTOSIS |
| AU2007307763A1 (en) | 2006-10-12 | 2008-04-17 | Novartis Ag | Pyrrolydine derivatives as IAP inhibitors |
| RU2009118487A (ru) * | 2006-10-19 | 2010-11-27 | Новартис АГ (CH) | Органические соединения |
| KR20090087094A (ko) * | 2006-11-28 | 2009-08-14 | 노파르티스 아게 | Ｉａｐ 억제제 및 ｆｌｔ3 억제제의 조합물 |
| EP2126188A1 (en) | 2006-12-26 | 2009-12-02 | Arçelik Anonim Sirketi | A washer / dryer with output from humidity sensor selectively input to control unit |
| WO2008109057A1 (en) * | 2007-03-02 | 2008-09-12 | Dana-Farber Cancer Institute, Inc. | Organic compounds and their uses |
| EP2296650B1 (en) * | 2008-05-16 | 2020-05-06 | Novartis AG | Immunomodulation by iap inhibitors |
-
2009
- 2009-05-14 EP EP09747530.5A patent/EP2296650B1/en active Active
- 2009-05-14 CN CN2009801276872A patent/CN102099035A/zh active Pending
- 2009-05-14 EA EA201071316A patent/EA201071316A1/ru unknown
- 2009-05-14 BR BRPI0912692A patent/BRPI0912692A2/pt not_active IP Right Cessation
- 2009-05-14 ES ES13178264T patent/ES2882855T3/es active Active
- 2009-05-14 WO PCT/US2009/043874 patent/WO2009140447A1/en not_active Ceased
- 2009-05-14 ES ES09747530T patent/ES2791957T3/es active Active
- 2009-05-14 EP EP13178264.1A patent/EP2698158B1/en active Active
- 2009-05-14 KR KR1020107028375A patent/KR20110022608A/ko not_active Withdrawn
- 2009-05-14 US US12/992,631 patent/US9750729B2/en active Active
- 2009-05-14 MX MX2010012231A patent/MX2010012231A/es not_active Application Discontinuation
- 2009-05-14 CA CA2724720A patent/CA2724720A1/en not_active Abandoned
- 2009-05-14 EP EP20159523.8A patent/EP3701947A1/en active Pending
- 2009-05-14 AU AU2009246347A patent/AU2009246347A1/en not_active Abandoned
- 2009-05-14 JP JP2011509678A patent/JP5779091B2/ja active Active
- 2009-05-15 TW TW098116299A patent/TW201006834A/zh unknown
- 2009-05-15 CL CL2009001195A patent/CL2009001195A1/es unknown
-
2010
- 2010-11-09 IL IL209203A patent/IL209203A0/en unknown
- 2010-11-15 ZA ZA2010/08176A patent/ZA201008176B/en unknown
- 2010-12-08 MA MA33406A patent/MA32388B1/fr unknown
-
2015
- 2015-03-02 JP JP2015040113A patent/JP5986655B2/ja active Active
- 2015-12-03 JP JP2015236482A patent/JP6030739B2/ja active Active
-
2017
- 2017-08-14 US US15/675,987 patent/US10786491B2/en active Active
-
2020
- 2020-07-13 US US16/926,930 patent/US11382905B2/en active Active
-
2022
- 2022-06-06 US US17/832,911 patent/US20220296581A1/en active Pending
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