JP2011523935A - シナプス後部を標的とした化学的除神経剤およびそれらの使用方法 - Google Patents
シナプス後部を標的とした化学的除神経剤およびそれらの使用方法 Download PDFInfo
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6634708P | 2008-02-19 | 2008-02-19 | |
| US61/066,347 | 2008-02-19 | ||
| PCT/US2009/034578 WO2009105585A2 (en) | 2008-02-19 | 2009-02-19 | Postsynaptically targeted chemodenervation agents and their methods of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011523935A true JP2011523935A (ja) | 2011-08-25 |
| JP2011523935A5 JP2011523935A5 (enExample) | 2013-04-11 |
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| JP2010547761A Pending JP2011523935A (ja) | 2008-02-19 | 2009-02-19 | シナプス後部を標的とした化学的除神経剤およびそれらの使用方法 |
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| Country | Link |
|---|---|
| US (1) | US9815875B2 (enExample) |
| EP (1) | EP2250193B1 (enExample) |
| JP (1) | JP2011523935A (enExample) |
| CN (1) | CN102007142A (enExample) |
| AU (1) | AU2009215436A1 (enExample) |
| CA (1) | CA2754352A1 (enExample) |
| ES (1) | ES2757648T3 (enExample) |
| IL (1) | IL207631A0 (enExample) |
| WO (1) | WO2009105585A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023511978A (ja) * | 2020-01-24 | 2023-03-23 | ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド | 外膜又は外膜周囲の神経アブレーションのための徐放性マトリックス及びその使用 |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7259237B1 (en) | 2006-12-29 | 2007-08-21 | Miller Kent D | Pan-antiviral peptides |
| JO3250B1 (ar) | 2009-09-22 | 2018-09-16 | Novartis Ag | إستعمال منشطات مستقبل نيكوتينيك أسيتيل كولين ألفا 7 |
| KR20120093312A (ko) * | 2009-10-30 | 2012-08-22 | 바이엘 헬스케어 엘엘씨 | 항체 모방체 스캐폴드 |
| US9220743B2 (en) | 2010-01-22 | 2015-12-29 | Nuovo Biologics, Llc | Pan-antiviral peptides for protein kinase inhibition |
| CN103145799B (zh) * | 2013-02-18 | 2014-04-16 | 大连理工大学 | 一组具有促进经皮和跨膜渗透作用的多肽及其应用 |
| CN104232653B (zh) * | 2014-09-19 | 2017-04-05 | 中南大学湘雅医院 | 重组α‑银环蛇毒素αBtx的制备方法 |
| JP2020518653A (ja) * | 2017-02-07 | 2020-06-25 | マイオセプト インコーポレイティド | 局所製剤及び方法 |
| CN110090296A (zh) * | 2018-09-21 | 2019-08-06 | 祁展楷 | 一组与烟碱乙酰胆碱受体具有高度亲和力能快速起效的眼镜蛇神经毒素分子在镇痛上的应用 |
| CN118561963A (zh) | 2018-10-16 | 2024-08-30 | 格罗制药公司 | 烟碱乙酰胆碱受体肽拮抗剂芋螺毒素组合物及相关方法 |
| AU2019408420B2 (en) * | 2018-12-21 | 2025-04-17 | Vib Vzw | Fusion protein with a toxin and scaffold protein |
| EP3753568A1 (en) * | 2019-06-21 | 2020-12-23 | Fastox Pharma SA | Composition modulating botulinum neurotoxin effect |
| CN110478473B (zh) * | 2019-07-14 | 2025-08-12 | 江苏毫末医药生物科技有限公司 | 眼镜蛇神经毒素多肽对鸦片类药品痛觉过敏和耐受的抑制及对其镇痛的协同增效作用 |
| EP4046648A4 (en) * | 2019-10-11 | 2023-10-18 | Qi, Zhankai | Application of elapidae snake postsynaptic neurotoxin monomer molecule in treatment of alzheimer's disease |
| CN111544571A (zh) * | 2020-06-02 | 2020-08-18 | 沈喆景 | 眼镜蛇科蛇突触后神经毒素在治疗与炎性细胞因子过度表达相关疾病的应用 |
| CN114409757B (zh) * | 2022-01-26 | 2023-07-18 | 云南南诏药业有限公司 | 一种蛇毒神经毒素及应用 |
Citations (2)
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|---|---|---|---|---|
| JP2004536103A (ja) * | 2001-05-24 | 2004-12-02 | イスム リサーチ ディベロップメント カンパニー オブ ザ ヘブライ 大学 オブ エルサレム | ヒトのアセチルコリンエステラーゼ（ａｃｈｅ）に対するアンチセンスオリゴヌクレオチド及びその使用 |
| WO2006047900A2 (de) * | 2004-11-02 | 2006-05-11 | Pentapharm Ag | Neue topisch anwendbare wirkstoffe gegen mimische und alterabedingt falten |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4447356A (en) * | 1981-04-17 | 1984-05-08 | Olivera Baldomero M | Conotoxins |
| FR2762009B1 (fr) * | 1997-04-10 | 1999-06-04 | Commissariat Energie Atomique | Enzymes recombinantes purifiees a activite prolylpeptidasique, leur procede de preparation et leurs applications |
| WO2007035474A2 (en) | 2005-09-15 | 2007-03-29 | Novomed Technologies, Inc. (Shanghai) | Transdermal delivery peptides and method of use thereof |
| US7659252B2 (en) * | 2005-09-15 | 2010-02-09 | Novomed Technologies, Inc. (Shanghai) | Transdermal delivery peptides and method of use thereof |
-
2009
- 2009-02-19 AU AU2009215436A patent/AU2009215436A1/en not_active Abandoned
- 2009-02-19 US US12/867,975 patent/US9815875B2/en not_active Expired - Fee Related
- 2009-02-19 CA CA2754352A patent/CA2754352A1/en not_active Abandoned
- 2009-02-19 JP JP2010547761A patent/JP2011523935A/ja active Pending
- 2009-02-19 ES ES09713319T patent/ES2757648T3/es active Active
- 2009-02-19 EP EP09713319.3A patent/EP2250193B1/en active Active
- 2009-02-19 CN CN2009801144924A patent/CN102007142A/zh active Pending
- 2009-02-19 WO PCT/US2009/034578 patent/WO2009105585A2/en not_active Ceased
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2010
- 2010-08-16 IL IL207631A patent/IL207631A0/en unknown
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004536103A (ja) * | 2001-05-24 | 2004-12-02 | イスム リサーチ ディベロップメント カンパニー オブ ザ ヘブライ 大学 オブ エルサレム | ヒトのアセチルコリンエステラーゼ（ａｃｈｅ）に対するアンチセンスオリゴヌクレオチド及びその使用 |
| WO2006047900A2 (de) * | 2004-11-02 | 2006-05-11 | Pentapharm Ag | Neue topisch anwendbare wirkstoffe gegen mimische und alterabedingt falten |
Non-Patent Citations (8)
| Title |
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| JPN6013049323; Ｔｏｘｉｃｏｎ，Ｖｏｌ．４４（２００４）ｐ．２９５-３０３ * |
| JPN6013049327; Ｊ．Ｐｒｏｔｅｏｍｅ Ｒｅｓ．，Ｖｏｌ．６（２００７）ｐ．３０９３-３１０７ * |
| JPN6013049328; Ｂｉｏｃｈｅｍ．Ｊ．，Ｖｏｌ．２０７（１９８２）ｐ．２１５-２２３ * |
| JPN6013049332; Ｃｅｌｌ．Ｍｏｌ．Ｌｉｆｅ Ｓｃｉ．，Ｖｏｌ．６４（２００７）ｐ．２８２９-２８４０ * |
| JPN6013049334; ＪＢＣ，Ｖｏｌ．２７６，Ｎｏ．２５（２００１）ｐ．２２９３０-２２９４０ * |
| JPN6013049335; ＢＢＲＣ，Ｖｏｌ．２６８（２０００）ｐ．４８０-４８４ * |
| JPN6013049338; ＥＭＢＯ Ｊ．，Ｖｏｌ．１，Ｎｏ．６（１９８２）ｐ．７１３-７１７ * |
| JPN6013049342; Ｍｏｌ．Ｃｅｌｌ．Ｐｒｏｔｅｏｍｉｃｓ，Ｖｏｌ．７，Ｎｏ．２（Ｆｅｂ．２００８）ｐ．２１５-２４６（Ｅｐｕｂ．Ｓｅｐｔ．２００７） * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023511978A (ja) * | 2020-01-24 | 2023-03-23 | ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド | 外膜又は外膜周囲の神経アブレーションのための徐放性マトリックス及びその使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| ES2757648T3 (es) | 2020-04-29 |
| CA2754352A1 (en) | 2009-08-27 |
| AU2009215436A1 (en) | 2009-08-27 |
| IL207631A0 (en) | 2010-12-30 |
| EP2250193A2 (en) | 2010-11-17 |
| US20110118190A1 (en) | 2011-05-19 |
| EP2250193B1 (en) | 2019-09-18 |
| US9815875B2 (en) | 2017-11-14 |
| CN102007142A (zh) | 2011-04-06 |
| WO2009105585A3 (en) | 2009-12-23 |
| WO2009105585A2 (en) | 2009-08-27 |
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