JP2011520992A5 - - Google Patents
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- Publication number
- JP2011520992A5 JP2011520992A5 JP2011510783A JP2011510783A JP2011520992A5 JP 2011520992 A5 JP2011520992 A5 JP 2011520992A5 JP 2011510783 A JP2011510783 A JP 2011510783A JP 2011510783 A JP2011510783 A JP 2011510783A JP 2011520992 A5 JP2011520992 A5 JP 2011520992A5
- Authority
- JP
- Japan
- Prior art keywords
- topical composition
- composition according
- otitis media
- eustachian tube
- betahistine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000699 topical effect Effects 0.000 claims 13
- 239000000203 mixture Substances 0.000 claims 12
- 206010015543 Eustachian tube dysfunction Diseases 0.000 claims 7
- 206010033078 Otitis media Diseases 0.000 claims 6
- UUQMNUMQCIQDMZ-UHFFFAOYSA-N betahistine Chemical compound CNCCC1=CC=CC=N1 UUQMNUMQCIQDMZ-UHFFFAOYSA-N 0.000 claims 5
- 229960004536 betahistine Drugs 0.000 claims 5
- 208000022760 infectious otitis media Diseases 0.000 claims 3
- 239000013543 active substance Substances 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000000850 decongestant Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 210000002388 eustachian tube Anatomy 0.000 claims 1
- 239000003172 expectorant agent Substances 0.000 claims 1
- 239000012458 free base Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229940066491 mucolytics Drugs 0.000 claims 1
- 239000007923 nasal drop Substances 0.000 claims 1
- 239000007922 nasal spray Substances 0.000 claims 1
- 229940097496 nasal spray Drugs 0.000 claims 1
- 210000001989 nasopharynx Anatomy 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2008902659 | 2008-05-27 | ||
| AU2008902659A AU2008902659A0 (en) | 2008-05-27 | Method of Treatment | |
| PCT/AU2009/000664 WO2009143572A1 (en) | 2008-05-27 | 2009-05-27 | Methods of treating mammals with eustachian tube dysfunctions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011520992A JP2011520992A (ja) | 2011-07-21 |
| JP2011520992A5 true JP2011520992A5 (enExample) | 2012-05-17 |
| JP5543963B2 JP5543963B2 (ja) | 2014-07-09 |
Family
ID=41376479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011510783A Expired - Fee Related JP5543963B2 (ja) | 2008-05-27 | 2009-05-27 | エウスタキオ管機能障害を有する哺乳動物の治療方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8642631B2 (enExample) |
| EP (1) | EP2293794B1 (enExample) |
| JP (1) | JP5543963B2 (enExample) |
| KR (1) | KR101621726B1 (enExample) |
| CN (1) | CN102046170B (enExample) |
| AU (1) | AU2009253739B2 (enExample) |
| BR (1) | BRPI0912126A2 (enExample) |
| CA (1) | CA2765190C (enExample) |
| DK (1) | DK2293794T3 (enExample) |
| EA (1) | EA022565B1 (enExample) |
| ES (1) | ES2419204T3 (enExample) |
| NZ (1) | NZ589742A (enExample) |
| PT (1) | PT2293794E (enExample) |
| WO (1) | WO2009143572A1 (enExample) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10105592A1 (de) | 2001-02-06 | 2002-08-08 | Achim Goepferich | Platzhalter zur Arzneistofffreigabe in der Stirnhöhle |
| US8317816B2 (en) | 2002-09-30 | 2012-11-27 | Acclarent, Inc. | Balloon catheters and methods for treating paranasal sinuses |
| US8435285B2 (en) * | 2003-11-25 | 2013-05-07 | Boston Scientific Scimed, Inc. | Composite stent with inner and outer stent elements and method of using the same |
| US8702626B1 (en) | 2004-04-21 | 2014-04-22 | Acclarent, Inc. | Guidewires for performing image guided procedures |
| US7419497B2 (en) | 2004-04-21 | 2008-09-02 | Acclarent, Inc. | Methods for treating ethmoid disease |
| US8932276B1 (en) | 2004-04-21 | 2015-01-13 | Acclarent, Inc. | Shapeable guide catheters and related methods |
| US20190314620A1 (en) | 2004-04-21 | 2019-10-17 | Acclarent, Inc. | Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures |
| US7654997B2 (en) | 2004-04-21 | 2010-02-02 | Acclarent, Inc. | Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat |
| US9089258B2 (en) | 2004-04-21 | 2015-07-28 | Acclarent, Inc. | Endoscopic methods and devices for transnasal procedures |
| US20070208252A1 (en) * | 2004-04-21 | 2007-09-06 | Acclarent, Inc. | Systems and methods for performing image guided procedures within the ear, nose, throat and paranasal sinuses |
| US8414473B2 (en) | 2004-04-21 | 2013-04-09 | Acclarent, Inc. | Methods and apparatus for treating disorders of the ear nose and throat |
| US7559925B2 (en) | 2006-09-15 | 2009-07-14 | Acclarent Inc. | Methods and devices for facilitating visualization in a surgical environment |
| US20060063973A1 (en) | 2004-04-21 | 2006-03-23 | Acclarent, Inc. | Methods and apparatus for treating disorders of the ear, nose and throat |
| US8747389B2 (en) | 2004-04-21 | 2014-06-10 | Acclarent, Inc. | Systems for treating disorders of the ear, nose and throat |
| US8894614B2 (en) | 2004-04-21 | 2014-11-25 | Acclarent, Inc. | Devices, systems and methods useable for treating frontal sinusitis |
| US9101384B2 (en) | 2004-04-21 | 2015-08-11 | Acclarent, Inc. | Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, Nose and/or throat |
| US7803150B2 (en) * | 2004-04-21 | 2010-09-28 | Acclarent, Inc. | Devices, systems and methods useable for treating sinusitis |
| US20070167682A1 (en) * | 2004-04-21 | 2007-07-19 | Acclarent, Inc. | Endoscopic methods and devices for transnasal procedures |
| US8764729B2 (en) | 2004-04-21 | 2014-07-01 | Acclarent, Inc. | Frontal sinus spacer |
| US9351750B2 (en) | 2004-04-21 | 2016-05-31 | Acclarent, Inc. | Devices and methods for treating maxillary sinus disease |
| US9554691B2 (en) | 2004-04-21 | 2017-01-31 | Acclarent, Inc. | Endoscopic methods and devices for transnasal procedures |
| US20060004323A1 (en) | 2004-04-21 | 2006-01-05 | Exploramed Nc1, Inc. | Apparatus and methods for dilating and modifying ostia of paranasal sinuses and other intranasal or paranasal structures |
| US9399121B2 (en) | 2004-04-21 | 2016-07-26 | Acclarent, Inc. | Systems and methods for transnasal dilation of passageways in the ear, nose or throat |
| US10188413B1 (en) | 2004-04-21 | 2019-01-29 | Acclarent, Inc. | Deflectable guide catheters and related methods |
| US7462175B2 (en) | 2004-04-21 | 2008-12-09 | Acclarent, Inc. | Devices, systems and methods for treating disorders of the ear, nose and throat |
| US8951225B2 (en) | 2005-06-10 | 2015-02-10 | Acclarent, Inc. | Catheters with non-removable guide members useable for treatment of sinusitis |
| US7816975B2 (en) * | 2005-09-20 | 2010-10-19 | Hewlett-Packard Development Company, L.P. | Circuit and method for bias voltage generation |
| US8114113B2 (en) | 2005-09-23 | 2012-02-14 | Acclarent, Inc. | Multi-conduit balloon catheter |
| US9820688B2 (en) | 2006-09-15 | 2017-11-21 | Acclarent, Inc. | Sinus illumination lightwire device |
| US8439687B1 (en) | 2006-12-29 | 2013-05-14 | Acclarent, Inc. | Apparatus and method for simulated insertion and positioning of guidewares and other interventional devices |
| WO2008124787A2 (en) | 2007-04-09 | 2008-10-16 | Acclarent, Inc. | Ethmoidotomy system and implantable spacer devices having therapeutic substance delivery capability for treatment of paranasal sinusitis |
| US8118757B2 (en) | 2007-04-30 | 2012-02-21 | Acclarent, Inc. | Methods and devices for ostium measurement |
| US8485199B2 (en) | 2007-05-08 | 2013-07-16 | Acclarent, Inc. | Methods and devices for protecting nasal turbinate during surgery |
| US10206821B2 (en) | 2007-12-20 | 2019-02-19 | Acclarent, Inc. | Eustachian tube dilation balloon with ventilation path |
| US8182432B2 (en) | 2008-03-10 | 2012-05-22 | Acclarent, Inc. | Corewire design and construction for medical devices |
| EP2664350B1 (en) | 2008-07-30 | 2019-08-28 | Acclarent, Inc. | Paranasal ostium finder devices |
| US20100241155A1 (en) | 2009-03-20 | 2010-09-23 | Acclarent, Inc. | Guide system with suction |
| US7978742B1 (en) | 2010-03-24 | 2011-07-12 | Corning Incorporated | Methods for operating diode lasers |
| US8435290B2 (en) * | 2009-03-31 | 2013-05-07 | Acclarent, Inc. | System and method for treatment of non-ventilating middle ear by providing a gas pathway through the nasopharynx |
| US9155492B2 (en) | 2010-09-24 | 2015-10-13 | Acclarent, Inc. | Sinus illumination lightwire device |
| US9433437B2 (en) | 2013-03-15 | 2016-09-06 | Acclarent, Inc. | Apparatus and method for treatment of ethmoid sinusitis |
| US9629684B2 (en) | 2013-03-15 | 2017-04-25 | Acclarent, Inc. | Apparatus and method for treatment of ethmoid sinusitis |
| US11410751B2 (en) * | 2016-05-27 | 2022-08-09 | Life Technologies Corporation | Methods and systems for graphical user interfaces for biological data |
| AR111699A1 (es) * | 2017-02-02 | 2019-08-14 | Otolanum Ag | Composición farmacéutica que comprende betahistina |
| AU2019208152B2 (en) * | 2017-03-22 | 2021-07-01 | Burkhard Karl-Heinz Gunther Franz | Treatment method |
| WO2018170532A1 (en) * | 2017-03-22 | 2018-09-27 | Franz, Lilian Ann | Treatment method |
| ES2950452T3 (es) | 2017-03-28 | 2023-10-10 | Intrabio Ltd | Betahistina, o una sal farmacéuticamente aceptable de la misma, e inhibidor de monoamina oxidasa, para su uso en el tratamiento o la prevención de uno o más síntomas de vértigo en un sujeto |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3149034A (en) | 1961-07-17 | 1964-09-15 | Umimed Inc | Method of relieving pain with (pyridyllower alkyl)-amines |
| US3632765A (en) | 1969-07-18 | 1972-01-04 | Unimed Inc | Treatment of shock |
| GB1241906A (en) * | 1969-11-01 | 1971-08-04 | Unimed Inc | Salts of beta-(pyridyl alkyl) amines with 21-hydroxy steroid polybasic acid esters |
| JPS5938202B2 (ja) * | 1976-03-05 | 1984-09-14 | エーザイ株式会社 | 難聴治療剤 |
| GB1577871A (en) * | 1976-05-28 | 1980-10-29 | Unimed Inc | Prevention of myocardial infarction |
| FR2397840B1 (enExample) * | 1977-07-22 | 1981-03-20 | Cherqui Jean | |
| FR2432313A1 (fr) | 1978-08-01 | 1980-02-29 | Foulhoux Pierre | Nouvelle forme galenique de la betahistine et son procede d'obtention |
| JPS55154915A (en) * | 1979-05-21 | 1980-12-02 | Jiyan Sadeia Shieruki | Medicine mold |
| DE3634016A1 (de) * | 1986-04-17 | 1987-10-29 | Lohmann Gmbh & Co Kg | Flaechenfoermiges therapeutisches system, verfahren zu seiner herstellung und seine verwendung |
| IT1229237B (it) | 1989-05-08 | 1991-07-26 | Prodotti Formenti | Sali di (2-(piridil)etil) metilammina |
| GB9104854D0 (en) | 1991-03-07 | 1991-04-17 | Reckitt & Colmann Prod Ltd | Sustained release compositions |
| JPH06219947A (ja) | 1993-01-26 | 1994-08-09 | Kinki Univ | 経皮投与製剤 |
| GB2280604B (en) | 1993-07-02 | 1997-04-30 | Resource Medical Limited | Processing of active agents |
| IT1309591B1 (it) | 1999-03-05 | 2002-01-24 | Formenti Farmaceutici Spa | Composizioni a rilascio controllato di betaistina. |
| JP2001064205A (ja) | 1999-06-25 | 2001-03-13 | Dai Ichi Seiyaku Co Ltd | 製剤組成物 |
| US6156294A (en) * | 1999-11-28 | 2000-12-05 | Scientific Development And Research, Inc. | Composition and method for treatment of otitis media |
| US20020106408A1 (en) | 2000-12-01 | 2002-08-08 | Johnatan Bacon | Prolamin-based sustained-release compositions and delayed-onset compositions |
| AU2002240359A1 (en) * | 2001-02-14 | 2002-08-28 | Sarfaraz K. Niazi | Pharmaceutical composition for the treatment of alopecia |
| US7090830B2 (en) * | 2001-05-24 | 2006-08-15 | Alexza Pharmaceuticals, Inc. | Drug condensation aerosols and kits |
| WO2002094240A1 (en) * | 2001-05-24 | 2002-11-28 | Alexza Molecular Delivery Corporation | Delivery of physiologically active compounds through an inhalation route |
| CA2446904A1 (en) * | 2001-05-24 | 2003-04-03 | Alexza Molecular Delivery Corporation | Delivery of drug esters through an inhalation route |
| WO2003026631A1 (en) | 2001-05-24 | 2003-04-03 | Alexza Molecular Delivery Corporation | Delivery of drug esters through an inhalation route |
| US20030051728A1 (en) * | 2001-06-05 | 2003-03-20 | Lloyd Peter M. | Method and device for delivering a physiologically active compound |
| WO2004089313A2 (en) | 2003-04-01 | 2004-10-21 | Transform Pharmaceuticals, Inc. | Novel olanzapine forms and related methods of treatment |
| AU2002316231A1 (en) | 2002-02-19 | 2003-09-29 | Xenoport, Inc. | Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof |
| AU2003243354A1 (en) | 2002-05-31 | 2003-12-19 | Transform Pharmaceuticals, Inc. | Novel conazole crystalline forms and related processes, pharmaceutical compositions and methods |
| GB0213869D0 (en) | 2002-06-17 | 2002-07-31 | Arakis Ltd | The treatment of pain |
| AU2003281158A1 (en) * | 2002-07-12 | 2004-02-02 | Arakis Ltd. | The treatment of emesis |
| US8487002B2 (en) * | 2002-10-25 | 2013-07-16 | Paladin Labs Inc. | Controlled-release compositions |
| DE60322091D1 (de) | 2002-10-25 | 2008-08-21 | Labopharm Inc | Zubereitungen mit kontrollierter freisetzung |
| RU2328275C2 (ru) | 2002-10-25 | 2008-07-10 | Лабофарм Инк. | Композиции трамадола пролонгированного высвобождения с 24-часовым действием |
| US7220431B2 (en) * | 2002-11-27 | 2007-05-22 | Regents Of The University Of Minnesota | Methods and compositions for applying pharmacologic agents to the ear |
| DK1493435T3 (da) | 2003-07-04 | 2008-09-08 | Formenti Farmaceutici Spa | Sammensætning af betahistin med styret frigivelse |
| WO2005011665A1 (en) * | 2003-07-22 | 2005-02-10 | Arakis Ltd. | The use of proglumide for the treatment of emesis |
| WO2005101979A2 (en) * | 2004-04-22 | 2005-11-03 | Mor Research Applications Ltd. | Method of food intake management |
| CN1568986A (zh) | 2004-05-13 | 2005-01-26 | 南昌弘益科技有限公司 | 盐酸倍他司汀滴丸及其制备方法 |
| GB0506800D0 (en) | 2005-04-04 | 2005-05-11 | Merck Sharp & Dohme | New uses |
| WO2006121979A2 (en) | 2005-05-09 | 2006-11-16 | Drugtech Corporation | Modified-release pharmaceutical compositions |
| US20070009564A1 (en) | 2005-06-22 | 2007-01-11 | Mcclain James B | Drug/polymer composite materials and methods of making the same |
| ES2691646T3 (es) | 2005-07-15 | 2018-11-28 | Micell Technologies, Inc. | Revestimientos poliméricos que contienen polvo de fármaco de morfología controlada |
| CN1732934B (zh) | 2005-08-10 | 2011-10-05 | 陈学峰 | 注射用盐酸倍他司汀冻干粉针剂及其制备方法 |
| US8158152B2 (en) * | 2005-11-18 | 2012-04-17 | Scidose Llc | Lyophilization process and products obtained thereby |
| WO2007076140A2 (en) | 2005-12-23 | 2007-07-05 | University Of Cincinnati | Treatment methods employing histamine h3 receptor antagonists, including betahistine |
| US7951845B2 (en) * | 2006-01-19 | 2011-05-31 | The Regents Of The University Of Michigan | Composition and method of treating hearing loss |
| US20070231390A1 (en) * | 2006-03-29 | 2007-10-04 | Andrx Labs, Llc | Formulations including hygroscopic compounds |
| RU2308941C1 (ru) | 2006-05-10 | 2007-10-27 | Открытое акционерное общество "Московское производственное химико-фармацевтическое объединение им. Н.А. Семашко" | Твердая лекарственная форма, обладающая гистаминоподобным действием, и способ ее получения |
| US20080066739A1 (en) * | 2006-09-20 | 2008-03-20 | Lemahieu Edward | Methods and systems of delivering medication via inhalation |
| JP5415769B2 (ja) * | 2006-12-26 | 2014-02-12 | 株式会社新日本科学 | 経鼻投与用製剤 |
| EP2125709A2 (en) * | 2007-02-02 | 2009-12-02 | Colucid Pharmaceuticals, Inc. | Compounds that inhibit cholinesterase |
-
2009
- 2009-05-27 US US12/994,709 patent/US8642631B2/en not_active Expired - Fee Related
- 2009-05-27 AU AU2009253739A patent/AU2009253739B2/en not_active Ceased
- 2009-05-27 BR BRPI0912126A patent/BRPI0912126A2/pt not_active Application Discontinuation
- 2009-05-27 EP EP09753336.8A patent/EP2293794B1/en not_active Not-in-force
- 2009-05-27 WO PCT/AU2009/000664 patent/WO2009143572A1/en not_active Ceased
- 2009-05-27 ES ES09753336T patent/ES2419204T3/es active Active
- 2009-05-27 NZ NZ589742A patent/NZ589742A/en not_active IP Right Cessation
- 2009-05-27 CN CN2009801195324A patent/CN102046170B/zh not_active Expired - Fee Related
- 2009-05-27 DK DK09753336.8T patent/DK2293794T3/da active
- 2009-05-27 EA EA201071361A patent/EA022565B1/ru not_active IP Right Cessation
- 2009-05-27 KR KR1020107029075A patent/KR101621726B1/ko not_active Expired - Fee Related
- 2009-05-27 JP JP2011510783A patent/JP5543963B2/ja not_active Expired - Fee Related
- 2009-05-27 CA CA2765190A patent/CA2765190C/en not_active Expired - Fee Related
- 2009-05-27 PT PT97533368T patent/PT2293794E/pt unknown
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