JP2011520983A5 - - Google Patents

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Publication number
JP2011520983A5
JP2011520983A5 JP2011510720A JP2011510720A JP2011520983A5 JP 2011520983 A5 JP2011520983 A5 JP 2011520983A5 JP 2011510720 A JP2011510720 A JP 2011510720A JP 2011510720 A JP2011510720 A JP 2011510720A JP 2011520983 A5 JP2011520983 A5 JP 2011520983A5
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JP
Japan
Prior art keywords
compound
oligonucleotide
independently
group
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011510720A
Other languages
English (en)
Japanese (ja)
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JP2011520983A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2009/044953 external-priority patent/WO2009143412A2/en
Publication of JP2011520983A publication Critical patent/JP2011520983A/ja
Publication of JP2011520983A5 publication Critical patent/JP2011520983A5/ja
Pending legal-status Critical Current

Links

JP2011510720A 2008-05-23 2009-05-22 オリゴヌクレオチドの送達のための細胞内遊離可能ジスルフィドリンカーを含有するポリマーシステム Pending JP2011520983A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US5595008P 2008-05-23 2008-05-23
US5586908P 2008-05-23 2008-05-23
US61/055,869 2008-05-23
US61/055,950 2008-05-23
US10657808P 2008-10-19 2008-10-19
US10657608P 2008-10-19 2008-10-19
US61/106,576 2008-10-19
US61/106,578 2008-10-19
PCT/US2009/044953 WO2009143412A2 (en) 2008-05-23 2009-05-22 Polymeric systems containing intracellular releasable disulfide linker for the delivery of oligonucleotides

Publications (2)

Publication Number Publication Date
JP2011520983A JP2011520983A (ja) 2011-07-21
JP2011520983A5 true JP2011520983A5 (https=) 2012-06-28

Family

ID=41340917

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011510720A Pending JP2011520983A (ja) 2008-05-23 2009-05-22 オリゴヌクレオチドの送達のための細胞内遊離可能ジスルフィドリンカーを含有するポリマーシステム

Country Status (6)

Country Link
US (1) US20110105413A1 (https=)
EP (1) EP2288261A4 (https=)
JP (1) JP2011520983A (https=)
CA (1) CA2723263A1 (https=)
TW (1) TW201004648A (https=)
WO (1) WO2009143412A2 (https=)

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MX2018009938A (es) 2016-03-01 2019-03-14 Ascendis Pharma Bone Diseases As Profarmacos de hormona paratiroidea (pth).
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EP3518961B1 (en) 2016-09-29 2023-02-22 Ascendis Pharma Bone Diseases A/S Pth compounds with low peak-to-trough ratios
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PL3793587T3 (pl) 2018-05-18 2025-09-22 Ascendis Pharma Bone Diseases A/S Dawka początkowa koniugatów PTH
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WO2020064847A1 (en) 2018-09-26 2020-04-02 Ascendis Pharma A/S Degradable hyaluronic acid hydrogels
AU2020204786A1 (en) 2019-01-04 2021-06-10 Ascendis Pharma Oncology Division A/S Induction of sustained local inflammation
TW202500188A (zh) 2019-01-04 2025-01-01 丹麥商阿仙帝斯製藥公司 模式辨別受體(pattern recognition receptor)促效劑的共軛物
EP3906065B1 (en) 2019-01-04 2025-04-30 Ascendis Pharma Oncology Division A/S Prr agonist for use in the treatment of cancer
BR112021010043A2 (pt) 2019-01-04 2021-10-26 Ascendis Pharma Oncology Division A/S Níveis de fármaco locais sustentados para agonistas imunes inatos
EP3923906A1 (en) 2019-02-11 2021-12-22 Ascendis Pharma Growth Disorders A/S Dry pharmaceutical formulations of cnp conjugates
CA3129357A1 (en) 2019-02-11 2020-08-20 Ascendis Pharma Bone Diseases A/S Liquid pharmaceutical formulations of pth conjugates
CA3143278A1 (en) 2019-06-21 2020-12-24 Ascendis Pharma Oncology Division A/S Tyrosine kinase inhibitor conjugates
WO2020254607A1 (en) 2019-06-21 2020-12-24 Ascendis Pharma Oncology Division A/S Anti-ctla4 compounds with localized pd properties
WO2020254617A1 (en) 2019-06-21 2020-12-24 Ascendis Pharma Oncology Division A/S Anti-ctla4 compounds with localized pk properties
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MX2022007371A (es) 2020-01-13 2022-07-12 Ascendis Pharma Bone Diseases As Tratamiento del hipoparatiroidismo.
CA3175974A1 (en) 2020-05-04 2021-11-11 Oliver Boris Stauch Hydrogel irradiation
MX2022014082A (es) 2020-06-03 2022-12-07 Ascendis Pharma Oncology Div A/S Secuencias de interleucina (il-2) y usos de las mismas.
JP2023540701A (ja) 2020-08-28 2023-09-26 アセンディス ファーマ オンコロジー ディヴィジョン エー／エス グリコシル化ｉｌ－２タンパク質及びその使用
AU2021349316A1 (en) 2020-09-28 2023-04-27 Ascendis Pharma Bone Diseases A/S Improvement of physical and mental well-being of patients with hypoparathyroidism
BR112023018802A2 (pt) 2021-04-01 2023-10-31 Ascendis Pharma As Uso de hormônio de crescimento de ação prolongada para o tratamento de doenças induzidas por inflamação
EP4331617A4 (en) * 2021-04-28 2025-11-12 Japan Science & Tech Agency ARTIFICIAL NUCLEIC ACID AND METHOD OF ADMINISTRATING NUCLEIC ACID USING IT
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CA3236278A1 (en) 2021-12-13 2023-06-22 Kennett Sprogoe Effective doses of cnp conjugates
IL316466A (en) 2022-05-23 2024-12-01 Ascendis Pharma Growth Disorders As Liquid pharmaceutical formulations of cnp compounds
WO2024094673A1 (en) 2022-11-02 2024-05-10 Ascendis Pharma Bone Diseases A/S Pth treatment regimen comprising two pth compounds
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TW202430223A (zh) 2023-01-05 2024-08-01 丹麥商阿仙帝斯眼科製藥有限公司 用於治療眼部病症之藥物結合物
TW202434299A (zh) 2023-01-05 2024-09-01 丹麥商阿仙帝斯製藥公司 製造水凝膠微球之方法
AU2024232125A1 (en) 2023-03-06 2025-08-28 Ascendis Pharma A/S Compounds of drugs with an albumin binding moiety
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CN121175071A (zh) 2023-05-09 2025-12-19 阿森迪斯药物肿瘤股份有限公司 使用il-2缀合物的新型癌症治疗方法
WO2025051711A1 (en) 2023-09-04 2025-03-13 Ascendis Pharma Bone Diseases A/S Pth treatment of chronic kidney disease
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