JP2011520936A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011520936A5 JP2011520936A5 JP2011509929A JP2011509929A JP2011520936A5 JP 2011520936 A5 JP2011520936 A5 JP 2011520936A5 JP 2011509929 A JP2011509929 A JP 2011509929A JP 2011509929 A JP2011509929 A JP 2011509929A JP 2011520936 A5 JP2011520936 A5 JP 2011520936A5
- Authority
- JP
- Japan
- Prior art keywords
- nanoemulsion
- component
- perfluorocarbon
- nanoemulsion according
- endocytosis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08156434A EP2123256A1 (en) | 2008-05-19 | 2008-05-19 | Perfluorcarbon nanoemulsions with endocytosis enhancing surface for gene-transfer |
| EP08156434.6 | 2008-05-19 | ||
| PCT/EP2009/055779 WO2009141257A1 (en) | 2008-05-19 | 2009-05-13 | Perfluorcarbon nanoemulsions with endocytosis enhancing surface for gene-transfer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011520936A JP2011520936A (ja) | 2011-07-21 |
| JP2011520936A5 true JP2011520936A5 (enExample) | 2012-12-27 |
| JP5546534B2 JP5546534B2 (ja) | 2014-07-09 |
Family
ID=39869983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011509929A Expired - Fee Related JP5546534B2 (ja) | 2008-05-19 | 2009-05-13 | 遺伝子導入のためのエンドサイトーシス促進表面を有するペルフルオロカーボンナノエマルション |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9616131B2 (enExample) |
| EP (3) | EP2123256A1 (enExample) |
| JP (1) | JP5546534B2 (enExample) |
| CN (2) | CN102847170B (enExample) |
| AU (1) | AU2009249812B2 (enExample) |
| CA (1) | CA2725513C (enExample) |
| DK (2) | DK2510921T3 (enExample) |
| ES (2) | ES2391375T3 (enExample) |
| HU (1) | HUE035320T2 (enExample) |
| IL (1) | IL209205A (enExample) |
| NZ (1) | NZ589417A (enExample) |
| PL (2) | PL2285349T3 (enExample) |
| WO (1) | WO2009141257A1 (enExample) |
| ZA (1) | ZA201008274B (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2123256A1 (en) | 2008-05-19 | 2009-11-25 | Ruhr-Universität Bochum | Perfluorcarbon nanoemulsions with endocytosis enhancing surface for gene-transfer |
| CN103764169B (zh) * | 2011-03-31 | 2017-06-13 | 康斯坦策·沙费尔 | 用于非病毒转移核酸的全氟化化合物 |
| CN103251980B (zh) * | 2013-05-17 | 2014-07-02 | 中国人民解放军第四军医大学 | 全氟三丁胺与纤维蛋白水凝胶复合的神经导管制备方法 |
| CN103263695B (zh) * | 2013-05-17 | 2014-10-29 | 中国人民解放军第四军医大学 | 全氟三乙胺乳液与种子细胞复合的神经导管制备方法 |
| EP2853595A1 (en) * | 2013-09-30 | 2015-04-01 | Soluventis GmbH | NOTCH 1 specific siRNA molecules |
| EP3549609A4 (en) * | 2016-12-01 | 2020-07-29 | Saitama University | ENDOCYTOSIS ACTIVATOR FOR DRUG DELIVERY SYSTEMS |
| WO2025080939A1 (en) | 2023-10-13 | 2025-04-17 | Ultragenyx Pharmaceutical, Inc. | Compositions and methods for treating conditions associated with cartilage oligomeric matrix protein (comp) mutations |
| WO2025128853A2 (en) | 2023-12-13 | 2025-06-19 | Ultragenyx Pharmaceutical Inc. | Compositions and methods for treating conditions associated with ube3a overexpression |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6050578B2 (ja) | 1981-12-25 | 1985-11-09 | 日本スチレンペ−パ−株式会社 | 合成樹脂発泡体の製造法 |
| FR2720943B1 (fr) | 1994-06-09 | 1996-08-23 | Applic Transferts Technolo | Emulsions inverses stables à forte concentration en composé(s) fluoré(s) et leur utilisation pour l'administration pulmonaire de médicaments et pour la fabrication d'émulsions multiples. |
| US6071890A (en) | 1994-12-09 | 2000-06-06 | Genzyme Corporation | Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy |
| EP0833608A2 (en) * | 1995-06-07 | 1998-04-08 | Alliance Pharmaceutical Corporation | Reverse fluorocarbon emulsion compositions for drug delivery |
| US5667809A (en) * | 1995-06-07 | 1997-09-16 | Alliance Pharmaceutical Corp. | Continuous fluorochemical microdispersions for the delivery of lipophilic pharmaceutical agents |
| JP2001002592A (ja) * | 1999-06-18 | 2001-01-09 | Dai Ichi Seiyaku Co Ltd | 遺伝子導入用組成物 |
| KR20080046750A (ko) | 2000-03-24 | 2008-05-27 | 바이오스피어 메디칼 인코포레이티드 | 능동 색전화용 미소구 |
| US20020155084A1 (en) * | 2000-06-02 | 2002-10-24 | The Regents Of The University Of The Michigan | Nanoemulsion formulations |
| KR20030039363A (ko) * | 2000-07-20 | 2003-05-17 | 오뜨끄리또에 악찌오네르노에 오브셰스뜨보 나우취노-쁘로이즈보드스뜨벤나야 피르마 "뻬르프또란" | 의료용 퍼플루오르 유기화합물의 유제 및 그 제조방법 및그것을 이용한 질병 치료 및 예방방법 |
| ATE392812T1 (de) | 2001-07-10 | 2008-05-15 | Sonogene Llc | Verbesserung der transfektion von dna in die leber |
| US20040115159A1 (en) | 2002-03-29 | 2004-06-17 | Tadlock Charles C | Novel nanoemulsions |
| GB0408164D0 (en) | 2004-04-13 | 2004-05-19 | Immune Targeting Systems Ltd | Antigen delivery vectors and constructs |
| US20070184076A1 (en) | 2006-02-07 | 2007-08-09 | Unger Evan C | Liquid-filled nanodroplets for anti-cancer therapy |
| EP1844772A1 (en) | 2006-04-06 | 2007-10-17 | Polyplus-Transfection SA | Compositions for transfection of oligonucleotides active for gene silencing and their biological and therapeutical applications |
| EP2123256A1 (en) | 2008-05-19 | 2009-11-25 | Ruhr-Universität Bochum | Perfluorcarbon nanoemulsions with endocytosis enhancing surface for gene-transfer |
-
2008
- 2008-05-19 EP EP08156434A patent/EP2123256A1/en not_active Withdrawn
-
2009
- 2009-05-13 NZ NZ589417A patent/NZ589417A/en not_active IP Right Cessation
- 2009-05-13 US US12/992,280 patent/US9616131B2/en not_active Expired - Fee Related
- 2009-05-13 DK DK12171341.6T patent/DK2510921T3/en active
- 2009-05-13 ES ES09749747T patent/ES2391375T3/es active Active
- 2009-05-13 CN CN201210345209.2A patent/CN102847170B/zh not_active Expired - Fee Related
- 2009-05-13 WO PCT/EP2009/055779 patent/WO2009141257A1/en not_active Ceased
- 2009-05-13 EP EP09749747A patent/EP2285349B1/en active Active
- 2009-05-13 HU HUE12171341A patent/HUE035320T2/en unknown
- 2009-05-13 DK DK09749747.3T patent/DK2285349T3/da active
- 2009-05-13 AU AU2009249812A patent/AU2009249812B2/en not_active Ceased
- 2009-05-13 PL PL09749747T patent/PL2285349T3/pl unknown
- 2009-05-13 ES ES12171341.6T patent/ES2642316T3/es active Active
- 2009-05-13 PL PL12171341T patent/PL2510921T3/pl unknown
- 2009-05-13 JP JP2011509929A patent/JP5546534B2/ja not_active Expired - Fee Related
- 2009-05-13 CA CA2725513A patent/CA2725513C/en active Active
- 2009-05-13 EP EP12171341.6A patent/EP2510921B1/en active Active
- 2009-05-13 CN CN200980118149.7A patent/CN102112109B/zh not_active Expired - Fee Related
-
2010
- 2010-11-09 IL IL209205A patent/IL209205A/en active IP Right Grant
- 2010-11-18 ZA ZA2010/08274A patent/ZA201008274B/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Huang et al. | The landscape of mRNA nanomedicine | |
| JP2011520936A5 (enExample) | ||
| JP5836394B2 (ja) | 陽イオン性脂質を含む陰イオン性薬物伝達体およびその製造方法 | |
| JP6038017B2 (ja) | 核酸を含む逆ミセル系及びその使用 | |
| EP3239132B1 (en) | Cationic lipid | |
| TWI594767B (zh) | 含有陽離子性脂質之藥物傳遞系統用脂質奈米粒子 | |
| KR101828877B1 (ko) | 음이온성 약물 함유 약제학적 조성물 및 그 제조방법 | |
| TW201534578A (zh) | 新穎脂質 | |
| WO2018230710A1 (ja) | siRNA細胞内送達のための脂質膜構造体 | |
| CA2748520A1 (en) | Pharmaceutical composition containing an anionic drug, and a production method therefor | |
| TW201330874A (zh) | 含有陽離子性脂質之組合之脂質奈米粒子 | |
| JP5546534B2 (ja) | 遺伝子導入のためのエンドサイトーシス促進表面を有するペルフルオロカーボンナノエマルション | |
| KR20190127277A (ko) | mRNA 전달용 고분자 나노입자 조성물 및 그 제조방법 | |
| WO2017048018A1 (ko) | 음이온성 약물 함유 약제학적 조성물 및 그 제조방법 | |
| TW201625310A (zh) | CKAP5基因表現抑制RNAi醫藥組合物 | |
| US20210346293A1 (en) | Lipid Vesicle for Oral Drug Delivery | |
| JP5349293B2 (ja) | 即効型核酸送達用キャリアー組成物 | |
| KR102772764B1 (ko) | 트레할로즈 유도체 및 신규 구조 유지 화합물을 포함하는 핵산 의약품 전달용 지질나노입자의 약학 조성물 | |
| US20230129386A1 (en) | Treatment of covid-19 with reverse micelle system comprising unmodified oligonucleotides | |
| TWI876778B (zh) | 用於傳遞核酸的基於環烷的脂質化合物以及包括其之脂質奈米粒子 | |
| WO2018225873A1 (ja) | 核酸含有ナノ粒子 | |
| TW201815736A (zh) | 作為陽離子性脂質之化合物 | |
| JP2023510253A (ja) | アルキル化ヌクレオシド、ならびにそれらの組成物および核酸送達のための方法 | |
| CN119775156A (zh) | 一种含氮链状化合物及其组合物 | |
| HK40059070A (en) | Lipid vesicle for oral drug delivery |