CN102847170B - 用于基因传递的具有增强内吞作用的表面的全氟化碳纳米乳液 - Google Patents
用于基因传递的具有增强内吞作用的表面的全氟化碳纳米乳液 Download PDFInfo
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- CN102847170B CN102847170B CN201210345209.2A CN201210345209A CN102847170B CN 102847170 B CN102847170 B CN 102847170B CN 201210345209 A CN201210345209 A CN 201210345209A CN 102847170 B CN102847170 B CN 102847170B
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| EP08156434A EP2123256A1 (en) | 2008-05-19 | 2008-05-19 | Perfluorcarbon nanoemulsions with endocytosis enhancing surface for gene-transfer |
| EP081564346 | 2008-05-19 | ||
| CN200980118149.7A CN102112109B (zh) | 2008-05-19 | 2009-05-13 | 用于基因传递的具有增强内吞作用的表面的全氟化碳纳米乳液 |
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| CN200980118149.7A Division CN102112109B (zh) | 2008-05-19 | 2009-05-13 | 用于基因传递的具有增强内吞作用的表面的全氟化碳纳米乳液 |
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| CN201210345209.2A Expired - Fee Related CN102847170B (zh) | 2008-05-19 | 2009-05-13 | 用于基因传递的具有增强内吞作用的表面的全氟化碳纳米乳液 |
| CN200980118149.7A Expired - Fee Related CN102112109B (zh) | 2008-05-19 | 2009-05-13 | 用于基因传递的具有增强内吞作用的表面的全氟化碳纳米乳液 |
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| EP (3) | EP2123256A1 (enExample) |
| JP (1) | JP5546534B2 (enExample) |
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| AU (1) | AU2009249812B2 (enExample) |
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| PL (2) | PL2285349T3 (enExample) |
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Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP2123256A1 (en) | 2008-05-19 | 2009-11-25 | Ruhr-Universität Bochum | Perfluorcarbon nanoemulsions with endocytosis enhancing surface for gene-transfer |
| CN103764169B (zh) * | 2011-03-31 | 2017-06-13 | 康斯坦策·沙费尔 | 用于非病毒转移核酸的全氟化化合物 |
| CN103251980B (zh) * | 2013-05-17 | 2014-07-02 | 中国人民解放军第四军医大学 | 全氟三丁胺与纤维蛋白水凝胶复合的神经导管制备方法 |
| CN103263695B (zh) * | 2013-05-17 | 2014-10-29 | 中国人民解放军第四军医大学 | 全氟三乙胺乳液与种子细胞复合的神经导管制备方法 |
| EP2853595A1 (en) * | 2013-09-30 | 2015-04-01 | Soluventis GmbH | NOTCH 1 specific siRNA molecules |
| EP3549609A4 (en) * | 2016-12-01 | 2020-07-29 | Saitama University | ENDOCYTOSIS ACTIVATOR FOR DRUG DELIVERY SYSTEMS |
| WO2025080939A1 (en) | 2023-10-13 | 2025-04-17 | Ultragenyx Pharmaceutical, Inc. | Compositions and methods for treating conditions associated with cartilage oligomeric matrix protein (comp) mutations |
| WO2025128853A2 (en) | 2023-12-13 | 2025-06-19 | Ultragenyx Pharmaceutical Inc. | Compositions and methods for treating conditions associated with ube3a overexpression |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1195981A (zh) * | 1995-06-07 | 1998-10-14 | 联合药品公司 | 药物输送用的反相碳氟化合物乳液组合物 |
| CN1454084A (zh) * | 2000-07-20 | 2003-11-05 | 佩尔夫托拉科研生产公众股份公司 | 一种用于医药目的的全氟有机化合物的乳液、其制备方法和利用其治疗和预防疾病的方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JPS6050578B2 (ja) | 1981-12-25 | 1985-11-09 | 日本スチレンペ−パ−株式会社 | 合成樹脂発泡体の製造法 |
| FR2720943B1 (fr) | 1994-06-09 | 1996-08-23 | Applic Transferts Technolo | Emulsions inverses stables à forte concentration en composé(s) fluoré(s) et leur utilisation pour l'administration pulmonaire de médicaments et pour la fabrication d'émulsions multiples. |
| US6071890A (en) | 1994-12-09 | 2000-06-06 | Genzyme Corporation | Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy |
| US5667809A (en) * | 1995-06-07 | 1997-09-16 | Alliance Pharmaceutical Corp. | Continuous fluorochemical microdispersions for the delivery of lipophilic pharmaceutical agents |
| JP2001002592A (ja) * | 1999-06-18 | 2001-01-09 | Dai Ichi Seiyaku Co Ltd | 遺伝子導入用組成物 |
| KR20080046750A (ko) | 2000-03-24 | 2008-05-27 | 바이오스피어 메디칼 인코포레이티드 | 능동 색전화용 미소구 |
| US20020155084A1 (en) * | 2000-06-02 | 2002-10-24 | The Regents Of The University Of The Michigan | Nanoemulsion formulations |
| ATE392812T1 (de) | 2001-07-10 | 2008-05-15 | Sonogene Llc | Verbesserung der transfektion von dna in die leber |
| US20040115159A1 (en) | 2002-03-29 | 2004-06-17 | Tadlock Charles C | Novel nanoemulsions |
| GB0408164D0 (en) | 2004-04-13 | 2004-05-19 | Immune Targeting Systems Ltd | Antigen delivery vectors and constructs |
| US20070184076A1 (en) | 2006-02-07 | 2007-08-09 | Unger Evan C | Liquid-filled nanodroplets for anti-cancer therapy |
| EP1844772A1 (en) | 2006-04-06 | 2007-10-17 | Polyplus-Transfection SA | Compositions for transfection of oligonucleotides active for gene silencing and their biological and therapeutical applications |
| EP2123256A1 (en) | 2008-05-19 | 2009-11-25 | Ruhr-Universität Bochum | Perfluorcarbon nanoemulsions with endocytosis enhancing surface for gene-transfer |
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2008
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2009
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- 2009-05-13 CN CN201210345209.2A patent/CN102847170B/zh not_active Expired - Fee Related
- 2009-05-13 WO PCT/EP2009/055779 patent/WO2009141257A1/en not_active Ceased
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- 2009-05-13 HU HUE12171341A patent/HUE035320T2/en unknown
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- 2009-05-13 AU AU2009249812A patent/AU2009249812B2/en not_active Ceased
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1195981A (zh) * | 1995-06-07 | 1998-10-14 | 联合药品公司 | 药物输送用的反相碳氟化合物乳液组合物 |
| CN1454084A (zh) * | 2000-07-20 | 2003-11-05 | 佩尔夫托拉科研生产公众股份公司 | 一种用于医药目的的全氟有机化合物的乳液、其制备方法和利用其治疗和预防疾病的方法 |
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| AU2009249812B2 (en) | 2013-08-22 |
| CN102112109B (zh) | 2016-10-12 |
| EP2510921B1 (en) | 2017-07-12 |
| HK1159479A1 (zh) | 2012-08-03 |
| DK2285349T3 (da) | 2012-10-22 |
| CN102847170A (zh) | 2013-01-02 |
| EP2285349A1 (en) | 2011-02-23 |
| CA2725513C (en) | 2013-07-02 |
| WO2009141257A1 (en) | 2009-11-26 |
| US9616131B2 (en) | 2017-04-11 |
| PL2285349T3 (pl) | 2012-12-31 |
| DK2510921T3 (en) | 2017-10-23 |
| CN102112109A (zh) | 2011-06-29 |
| AU2009249812A1 (en) | 2009-11-26 |
| EP2510921A1 (en) | 2012-10-17 |
| NZ589417A (en) | 2012-03-30 |
| HK1179533A1 (zh) | 2013-10-04 |
| IL209205A (en) | 2015-08-31 |
| ES2391375T3 (es) | 2012-11-23 |
| CA2725513A1 (en) | 2009-11-26 |
| HUE035320T2 (en) | 2018-05-02 |
| EP2123256A1 (en) | 2009-11-25 |
| EP2285349B1 (en) | 2012-07-11 |
| IL209205A0 (en) | 2011-01-31 |
| ES2642316T3 (es) | 2017-11-16 |
| JP2011520936A (ja) | 2011-07-21 |
| US20110091561A1 (en) | 2011-04-21 |
| JP5546534B2 (ja) | 2014-07-09 |
| ZA201008274B (en) | 2012-02-29 |
| PL2510921T3 (pl) | 2017-12-29 |
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