JP2011519960A5 - - Google Patents

Info

Publication number

JP2011519960A5

JP2011519960A5 JP2011508768A JP2011508768A JP2011519960A5 JP 2011519960 A5 JP2011519960 A5 JP 2011519960A5 JP 2011508768 A JP2011508768 A JP 2011508768A JP 2011508768 A JP2011508768 A JP 2011508768A JP 2011519960 A5 JP2011519960 A5 JP 2011519960A5

Authority

JP

Japan

Prior art keywords

angiogenin

prophylactic

agent according

muscular dystrophy

therapeutic agent

Prior art date

2009-05-14

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
• Discuss

• 102100022987 Angiogenin Human genes 0.000 claims 8
• 108010072788 angiogenin Proteins 0.000 claims 8
• 239000003814 drug Substances 0.000 claims 5
• 230000000069 prophylactic effect Effects 0.000 claims 5
• 229940124597 therapeutic agent Drugs 0.000 claims 5
• NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims 4
• 102000016970 Follistatin Human genes 0.000 claims 3
• 108010014612 Follistatin Proteins 0.000 claims 3
• 208000001132 Osteoporosis Diseases 0.000 claims 3
• 239000003795 chemical substances by application Substances 0.000 claims 3
• 201000000585 muscular atrophy Diseases 0.000 claims 3
• 238000011321 prophylaxis Methods 0.000 claims 3
• 102000004877 Insulin Human genes 0.000 claims 2
• 108090001061 Insulin Proteins 0.000 claims 2
• 206010028289 Muscle atrophy Diseases 0.000 claims 2
• 206010002026 amyotrophic lateral sclerosis Diseases 0.000 claims 2
• 230000001419 dependent effect Effects 0.000 claims 2
• 206010012601 diabetes mellitus Diseases 0.000 claims 2
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
• 208000035475 disorder Diseases 0.000 claims 2
• 229940125396 insulin Drugs 0.000 claims 2
• 201000006938 muscular dystrophy Diseases 0.000 claims 2
• 230000001314 paroxysmal effect Effects 0.000 claims 2
• 208000000103 Anorexia Nervosa Diseases 0.000 claims 1
• 206010003694 Atrophy Diseases 0.000 claims 1
• 241000283690 Bos taurus Species 0.000 claims 1
• 206010006895 Cachexia Diseases 0.000 claims 1
• 208000037141 Congenital muscular dystrophy, Fukuyama type Diseases 0.000 claims 1
• 208000035810 Denervation atrophy Diseases 0.000 claims 1
• 206010013801 Duchenne Muscular Dystrophy Diseases 0.000 claims 1
• 201000006813 Fukuyama congenital muscular dystrophy Diseases 0.000 claims 1
• 208000002705 Glucose Intolerance Diseases 0.000 claims 1
• 206010022489 Insulin Resistance Diseases 0.000 claims 1
• 201000009342 Limb-girdle muscular dystrophy Diseases 0.000 claims 1
• 208000029725 Metabolic bone disease Diseases 0.000 claims 1
• 208000021642 Muscular disease Diseases 0.000 claims 1
• 206010028372 Muscular weakness Diseases 0.000 claims 1
• 206010028629 Myoglobinuria Diseases 0.000 claims 1
• 208000008589 Obesity Diseases 0.000 claims 1
• 206010049088 Osteopenia Diseases 0.000 claims 1
• 206010033799 Paralysis Diseases 0.000 claims 1
• 208000005770 Secondary Hyperparathyroidism Diseases 0.000 claims 1
• 206010047626 Vitamin D Deficiency Diseases 0.000 claims 1
• 201000006793 Walker-Warburg syndrome Diseases 0.000 claims 1
• 239000003098 androgen Substances 0.000 claims 1
• 230000037444 atrophy Effects 0.000 claims 1
• 230000003796 beauty Effects 0.000 claims 1
• 230000009286 beneficial effect Effects 0.000 claims 1
• 210000000988 bone and bone Anatomy 0.000 claims 1
• 208000003295 carpal tunnel syndrome Diseases 0.000 claims 1
• 230000009693 chronic damage Effects 0.000 claims 1
• 208000016097 disease of metabolism Diseases 0.000 claims 1
• 230000001815 facial effect Effects 0.000 claims 1
• 230000006589 gland dysfunction Effects 0.000 claims 1
• 239000003862 glucocorticoid Substances 0.000 claims 1
• 201000001421 hyperglycemia Diseases 0.000 claims 1
• 208000014674 injury Diseases 0.000 claims 1
• 230000007774 longterm Effects 0.000 claims 1
• 230000007246 mechanism Effects 0.000 claims 1
• 208000030159 metabolic disease Diseases 0.000 claims 1
• 239000008267 milk Substances 0.000 claims 1
• 210000004080 milk Anatomy 0.000 claims 1
• 235000013336 milk Nutrition 0.000 claims 1
• 210000003205 muscle Anatomy 0.000 claims 1
• 230000020763 muscle atrophy Effects 0.000 claims 1
• 230000003387 muscular Effects 0.000 claims 1
• 208000025855 muscular dystrophy-dystroglycanopathy (congenital with brain and eye anomalies), type A, 4 Diseases 0.000 claims 1
• 230000036473 myasthenia Effects 0.000 claims 1
• 206010028417 myasthenia gravis Diseases 0.000 claims 1
• 208000018360 neuromuscular disease Diseases 0.000 claims 1
• 235000020824 obesity Nutrition 0.000 claims 1
• 210000000056 organ Anatomy 0.000 claims 1
• 201000008482 osteoarthritis Diseases 0.000 claims 1
• 208000021090 palsy Diseases 0.000 claims 1
• 230000000737 periodic effect Effects 0.000 claims 1
• 239000000546 pharmaceutical excipient Substances 0.000 claims 1
• 201000009104 prediabetes syndrome Diseases 0.000 claims 1
• 230000002028 premature Effects 0.000 claims 1
• 102000004169 proteins and genes Human genes 0.000 claims 1
• 108090000623 proteins and genes Proteins 0.000 claims 1
• 208000001076 sarcopenia Diseases 0.000 claims 1
• 208000000943 scapulohumeral muscular dystrophy Diseases 0.000 claims 1
• 230000001629 suppression Effects 0.000 claims 1
• 208000011580 syndromic disease Diseases 0.000 claims 1
• 238000002560 therapeutic procedure Methods 0.000 claims 1
• 230000008733 trauma Effects 0.000 claims 1
• 230000008736 traumatic injury Effects 0.000 claims 1
• 208000001072 type 2 diabetes mellitus Diseases 0.000 claims 1
• 230000029663 wound healing Effects 0.000 claims 1