JP2011519030A5 - - Google Patents
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- Publication number
- JP2011519030A5 JP2011519030A5 JP2011505533A JP2011505533A JP2011519030A5 JP 2011519030 A5 JP2011519030 A5 JP 2011519030A5 JP 2011505533 A JP2011505533 A JP 2011505533A JP 2011505533 A JP2011505533 A JP 2011505533A JP 2011519030 A5 JP2011519030 A5 JP 2011519030A5
- Authority
- JP
- Japan
- Prior art keywords
- protein
- activity
- measuring
- chitinase
- marker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 12
- 108090000623 proteins and genes Proteins 0.000 claims 10
- 102000004169 proteins and genes Human genes 0.000 claims 10
- 230000000694 effects Effects 0.000 claims 9
- 108010022172 Chitinases Proteins 0.000 claims 7
- 101000741307 Bothrops atrox Batroxicidin Proteins 0.000 claims 3
- 101000741308 Bothrops lutzi Lutzicidin Proteins 0.000 claims 3
- 101000741306 Crotalus durissus cascavella Cathelicidin-related peptide isoform 3 Proteins 0.000 claims 3
- 101000741303 Crotalus durissus terrificus Crotalicidin Proteins 0.000 claims 3
- 101000741319 Lachesis muta rhombeata Lachesicidin Proteins 0.000 claims 3
- 101000932958 Pseudonaja textilis Cathelicidin-related peptide Pt_CRAMP1 Proteins 0.000 claims 3
- 101000741290 Pseudonaja textilis Cathelicidin-related peptide Pt_CRAMP2 Proteins 0.000 claims 3
- 102000005465 Stathmin Human genes 0.000 claims 3
- 108050003387 Stathmin Proteins 0.000 claims 3
- 230000032683 aging Effects 0.000 claims 3
- 108010057612 1,4-beta-chitobiosidase Proteins 0.000 claims 2
- 101000588395 Bacillus subtilis (strain 168) Beta-hexosaminidase Proteins 0.000 claims 2
- 102000012286 Chitinases Human genes 0.000 claims 2
- 208000017667 Chronic Disease Diseases 0.000 claims 2
- 230000005778 DNA damage Effects 0.000 claims 2
- 231100000277 DNA damage Toxicity 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 210000004369 blood Anatomy 0.000 claims 2
- 239000008280 blood Substances 0.000 claims 2
- 210000001124 body fluid Anatomy 0.000 claims 2
- 239000010839 body fluid Substances 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 230000004064 dysfunction Effects 0.000 claims 2
- 230000002255 enzymatic effect Effects 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 239000003550 marker Substances 0.000 claims 2
- 238000005259 measurement Methods 0.000 claims 2
- 108020004999 messenger RNA Proteins 0.000 claims 2
- 239000012474 protein marker Substances 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 108091035539 telomere Proteins 0.000 claims 2
- 102000055501 telomere Human genes 0.000 claims 2
- 210000003411 telomere Anatomy 0.000 claims 2
- 210000001519 tissue Anatomy 0.000 claims 2
- 208000005623 Carcinogenesis Diseases 0.000 claims 1
- 101000906941 Mus musculus Chitinase-like protein 3 Proteins 0.000 claims 1
- 230000004071 biological effect Effects 0.000 claims 1
- 238000001574 biopsy Methods 0.000 claims 1
- 230000036952 cancer formation Effects 0.000 claims 1
- 231100000504 carcinogenesis Toxicity 0.000 claims 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 238000003384 imaging method Methods 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 230000033667 organ regeneration Effects 0.000 claims 1
- 238000004393 prognosis Methods 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 230000017423 tissue regeneration Effects 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08155176.4 | 2008-04-25 | ||
| EP08155176 | 2008-04-25 | ||
| PCT/EP2009/055059 WO2009130330A1 (de) | 2008-04-25 | 2009-04-27 | Marker zur bestimmung der biologischen alterung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011519030A JP2011519030A (ja) | 2011-06-30 |
| JP2011519030A5 true JP2011519030A5 (https=) | 2012-07-26 |
Family
ID=39651415
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011505533A Pending JP2011519030A (ja) | 2008-04-25 | 2009-04-27 | ヒトおよび動物における生物学的老化、再生能、発癌リスク、加齢性疾患を発症するリスクおよび慢性疾患の予後を測定するための、ｄｎａ損傷およびテロメア機能不全を測定するためのマーカー |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20110104698A1 (https=) |
| EP (1) | EP2281202A1 (https=) |
| JP (1) | JP2011519030A (https=) |
| WO (1) | WO2009130330A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105246490A (zh) * | 2013-03-15 | 2016-01-13 | 伊利克斯根公司 | 使用zscan4复壮人细胞的方法 |
| WO2019098194A1 (ja) * | 2017-11-14 | 2019-05-23 | 国立大学法人広島大学 | 老化状態の評価方法、情報の提示方法、及び老化状態を改善又は予防する物質のスクリーニング方法 |
| EP3674418A1 (en) * | 2018-12-26 | 2020-07-01 | Life Length S.L. | Method for measuring telomere associated variables and uses thereof for the diagnosis and/or prognosis of telomeric-associated diseases |
| CN111333713B (zh) * | 2020-03-27 | 2021-06-25 | 江南大学 | 一种表达抗菌肽基因的植物乳杆菌 |
| CN111398456A (zh) * | 2020-03-31 | 2020-07-10 | 中国科学院昆明动物研究所 | 指征健康老龄关键通路的内源性代谢小分子标志物及应用 |
| CN115697644A (zh) * | 2020-06-16 | 2023-02-03 | 发那科株式会社 | 具备工具设定管理功能的控制装置、控制系统及工具 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0575906A2 (en) * | 1992-06-19 | 1993-12-29 | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. | Sandwich immunoassay of beta-N-acetylglucosaminidase and monoclonal antibody used therein |
| JPH08319298A (ja) * | 1995-05-25 | 1996-12-03 | Fujirebio Inc | 抗ヒト老化マーカータンパク質モノクローナル抗体及びそれを用いる測定方法 |
| JP3754611B2 (ja) * | 2000-10-03 | 2006-03-15 | 旭テクノグラス株式会社 | ヒト老化マーカー及びストレスマーカーの検定方法 |
| DE60229238D1 (de) * | 2001-02-21 | 2008-11-20 | Univ Rush Medical Center | Bestimmung von knorpel-degeneration und -alterung unter verwendung von knochenmorphogeneseproteinen |
| US7041449B2 (en) * | 2001-03-19 | 2006-05-09 | Wisconsin Alumni Research Foundation | Methods of screening for compounds that inhibit expression of biomarker sequences differentially expressed with age in mice |
| AU2003240326A1 (en) * | 2002-06-07 | 2003-12-22 | Cancer Care Ontario | Eef1a2 for use in the prognosis, diagnosis and treatment of cancer |
| WO2007082073A2 (en) * | 2006-01-11 | 2007-07-19 | The Regents Of The University Of California | Biomarkers for oral tongue cancer metastasis and extracapsular spread (ecs) |
-
2009
- 2009-04-27 US US12/989,545 patent/US20110104698A1/en not_active Abandoned
- 2009-04-27 JP JP2011505533A patent/JP2011519030A/ja active Pending
- 2009-04-27 WO PCT/EP2009/055059 patent/WO2009130330A1/de not_active Ceased
- 2009-04-27 EP EP09734665A patent/EP2281202A1/de not_active Withdrawn
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