JP2011518828A5 - - Google Patents
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- Publication number
- JP2011518828A5 JP2011518828A5 JP2011506352A JP2011506352A JP2011518828A5 JP 2011518828 A5 JP2011518828 A5 JP 2011518828A5 JP 2011506352 A JP2011506352 A JP 2011506352A JP 2011506352 A JP2011506352 A JP 2011506352A JP 2011518828 A5 JP2011518828 A5 JP 2011518828A5
- Authority
- JP
- Japan
- Prior art keywords
- pai
- medicament
- compound
- combinations
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4817608P | 2008-04-26 | 2008-04-26 | |
| US61/048,176 | 2008-04-26 | ||
| US12/421,456 | 2009-04-09 | ||
| US12/421,456 US20090202524A1 (en) | 2007-10-31 | 2009-04-09 | Pai-1 expression and activity inhibitors for the treatment of ocular disorders |
| PCT/US2009/040149 WO2009131850A2 (en) | 2008-04-26 | 2009-04-10 | Pai-1 expression and activity inhibitors for the treatment of ocular disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011518828A JP2011518828A (ja) | 2011-06-30 |
| JP2011518828A5 true JP2011518828A5 (https=) | 2013-03-14 |
Family
ID=40810596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011506352A Pending JP2011518828A (ja) | 2008-04-26 | 2009-04-10 | 眼球障害の処置のためのｐａｉ−１の発現および活性インヒビター |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20090202524A1 (https=) |
| EP (1) | EP2296647A2 (https=) |
| JP (1) | JP2011518828A (https=) |
| KR (1) | KR20100135953A (https=) |
| CN (1) | CN102046168A (https=) |
| AR (1) | AR071393A1 (https=) |
| CL (1) | CL2009000986A1 (https=) |
| TW (1) | TW200946113A (https=) |
| UY (1) | UY31786A1 (https=) |
| WO (1) | WO2009131850A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE404189T1 (de) * | 2004-04-26 | 2008-08-15 | Alcon Inc | Statine zur behandlung von okularer hypertonie und glaukom |
| US10946076B2 (en) * | 2013-02-13 | 2021-03-16 | The Research Foundation For The State University Of New York | Glaucoma treatment |
| HK1221725A1 (zh) | 2013-08-13 | 2017-06-09 | Sanofi | 纤溶酶原激活剂抑制剂-1(pai-1)的抗体及其用途 |
| WO2015072580A1 (ja) | 2013-11-14 | 2015-05-21 | 学校法人同志社 | 細胞増殖促進または細胞障害抑制による角膜内皮治療薬 |
| JPWO2017110093A1 (ja) | 2015-12-24 | 2018-10-11 | 学校法人同志社 | ＴＧＦ−βシグナルに起因する障害を治療または予防するための医薬およびその応用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4214215A1 (de) * | 1992-04-30 | 1993-11-04 | Behringwerke Ag | Verwendung von inhibitoren von plasminogenaktivatoren zur behandlung von entzuendungen |
| AU771635B2 (en) * | 1999-01-05 | 2004-04-01 | American National Red Cross, The | Methods for treating conditions associated with the accumulation of excess extracellular matrix |
| US7074817B2 (en) * | 2001-06-20 | 2006-07-11 | Wyeth | Substituted indole acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1) |
| US7351407B2 (en) * | 2002-04-30 | 2008-04-01 | Alcon, Inc. | Agents which regulate, inhibit, or modulate the activity and/or expression of connective tissue growth factor (CTGF) as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies |
| JP2007512347A (ja) * | 2003-11-26 | 2007-05-17 | デューク・ユニバーシティー | 緑内障を予防するかまたは治療する方法 |
| ATE404189T1 (de) * | 2004-04-26 | 2008-08-15 | Alcon Inc | Statine zur behandlung von okularer hypertonie und glaukom |
| WO2006040839A1 (ja) * | 2004-10-15 | 2006-04-20 | Advanced Medicine Research Institute | 眼疾患処置用点眼剤及びキット |
| US7803824B2 (en) * | 2004-10-29 | 2010-09-28 | Alcon, Inc. | Use of inhibitors of Jun N-terminal kinases to treat glaucoma |
| US20060094753A1 (en) * | 2004-10-29 | 2006-05-04 | Alcon, Inc. | Use of inhibitors of Jun N-terminal kinases for the treatment of glaucomatous retinopathy and ocular diseases |
| AU2007238608A1 (en) * | 2006-04-14 | 2007-10-25 | Massachusetts Institute Of Technology | Identifying and modulating molecular pathways that mediate nervous system plasticity |
| WO2008055205A2 (en) * | 2006-10-31 | 2008-05-08 | Alcon Research, Ltd. | Pai-1 binding modulators for the treatment of ocular disorders |
-
2009
- 2009-04-09 US US12/421,456 patent/US20090202524A1/en not_active Abandoned
- 2009-04-10 EP EP09735222A patent/EP2296647A2/en not_active Withdrawn
- 2009-04-10 KR KR1020107026494A patent/KR20100135953A/ko not_active Withdrawn
- 2009-04-10 CN CN2009801185568A patent/CN102046168A/zh active Pending
- 2009-04-10 JP JP2011506352A patent/JP2011518828A/ja active Pending
- 2009-04-10 WO PCT/US2009/040149 patent/WO2009131850A2/en not_active Ceased
- 2009-04-21 TW TW098113153A patent/TW200946113A/zh unknown
- 2009-04-22 AR ARP090101418A patent/AR071393A1/es not_active Application Discontinuation
- 2009-04-24 CL CL2009000986A patent/CL2009000986A1/es unknown
- 2009-04-24 UY UY31786A patent/UY31786A1/es not_active Application Discontinuation
-
2011
- 2011-01-14 US US13/006,984 patent/US20110105574A1/en not_active Abandoned
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