JP2011518828A5 - - Google Patents
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- Publication number
- JP2011518828A5 JP2011518828A5 JP2011506352A JP2011506352A JP2011518828A5 JP 2011518828 A5 JP2011518828 A5 JP 2011518828A5 JP 2011506352 A JP2011506352 A JP 2011506352A JP 2011506352 A JP2011506352 A JP 2011506352A JP 2011518828 A5 JP2011518828 A5 JP 2011518828A5
- Authority
- JP
- Japan
- Prior art keywords
- pai
- medicament
- compound
- combinations
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4817608P | 2008-04-26 | 2008-04-26 | |
| US61/048,176 | 2008-04-26 | ||
| US12/421,456 US20090202524A1 (en) | 2007-10-31 | 2009-04-09 | Pai-1 expression and activity inhibitors for the treatment of ocular disorders |
| US12/421,456 | 2009-04-09 | ||
| PCT/US2009/040149 WO2009131850A2 (en) | 2008-04-26 | 2009-04-10 | Pai-1 expression and activity inhibitors for the treatment of ocular disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011518828A JP2011518828A (ja) | 2011-06-30 |
| JP2011518828A5 true JP2011518828A5 (https=) | 2013-03-14 |
Family
ID=40810596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011506352A Pending JP2011518828A (ja) | 2008-04-26 | 2009-04-10 | 眼球障害の処置のためのｐａｉ−１の発現および活性インヒビター |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20090202524A1 (https=) |
| EP (1) | EP2296647A2 (https=) |
| JP (1) | JP2011518828A (https=) |
| KR (1) | KR20100135953A (https=) |
| CN (1) | CN102046168A (https=) |
| AR (1) | AR071393A1 (https=) |
| CL (1) | CL2009000986A1 (https=) |
| TW (1) | TW200946113A (https=) |
| UY (1) | UY31786A1 (https=) |
| WO (1) | WO2009131850A2 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2311986T3 (es) * | 2004-04-26 | 2009-02-16 | Alcon, Inc. | Estatinas para el tratamiento de la hipertension ocular y del glaucoma. |
| WO2014126997A1 (en) * | 2013-02-13 | 2014-08-21 | The Research Foundation For The State University Of New York | Glaucoma treatment |
| TN2016000048A1 (en) | 2013-08-13 | 2017-07-05 | Sanofi Sa | Antibodies to plasminogen activator inhibitor-1 (pai-1) and uses thereof |
| WO2015072580A1 (ja) | 2013-11-14 | 2015-05-21 | 学校法人同志社 | 細胞増殖促進または細胞障害抑制による角膜内皮治療薬 |
| JPWO2017110093A1 (ja) | 2015-12-24 | 2018-10-11 | 学校法人同志社 | ＴＧＦ−βシグナルに起因する障害を治療または予防するための医薬およびその応用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4214215A1 (de) * | 1992-04-30 | 1993-11-04 | Behringwerke Ag | Verwendung von inhibitoren von plasminogenaktivatoren zur behandlung von entzuendungen |
| WO2000040227A2 (en) * | 1999-01-05 | 2000-07-13 | University Of Utah | Methods for treating conditions associated with the accumulation of excess extracellular matrix |
| DE60221391T2 (de) * | 2001-06-20 | 2008-04-17 | Wyeth | Substituierte indolsäurederivate als inhibitoren von plasminogen-aktivator-inhibitor-1 (pai-1) |
| WO2003092584A2 (en) * | 2002-04-30 | 2003-11-13 | Alcon, Inc. | Agents which regulate, inhibit, or modulate the activity and/or expression of connective tissue growth factor (ctgf) as a unique means to both lower intraocular pressure and treat glaucomatous retinopathies/optic neuropathies |
| WO2005053683A1 (en) * | 2003-11-26 | 2005-06-16 | Duke University | A method of preventing or treating glaucoma |
| ES2311986T3 (es) * | 2004-04-26 | 2009-02-16 | Alcon, Inc. | Estatinas para el tratamiento de la hipertension ocular y del glaucoma. |
| WO2006040839A1 (ja) * | 2004-10-15 | 2006-04-20 | Advanced Medicine Research Institute | 眼疾患処置用点眼剤及びキット |
| US7803824B2 (en) * | 2004-10-29 | 2010-09-28 | Alcon, Inc. | Use of inhibitors of Jun N-terminal kinases to treat glaucoma |
| US20060094753A1 (en) * | 2004-10-29 | 2006-05-04 | Alcon, Inc. | Use of inhibitors of Jun N-terminal kinases for the treatment of glaucomatous retinopathy and ocular diseases |
| CA2650140A1 (en) * | 2006-04-14 | 2007-10-25 | Mriganka Sur | Identifying and modulating molecular pathways that mediate nervous system plasticity |
| RU2465898C2 (ru) * | 2006-10-31 | 2012-11-10 | Алькон Рисерч, Лтд. | Модуляторы связывания pai-1 для лечения глазных болезней |
-
2009
- 2009-04-09 US US12/421,456 patent/US20090202524A1/en not_active Abandoned
- 2009-04-10 KR KR1020107026494A patent/KR20100135953A/ko not_active Withdrawn
- 2009-04-10 WO PCT/US2009/040149 patent/WO2009131850A2/en not_active Ceased
- 2009-04-10 CN CN2009801185568A patent/CN102046168A/zh active Pending
- 2009-04-10 EP EP09735222A patent/EP2296647A2/en not_active Withdrawn
- 2009-04-10 JP JP2011506352A patent/JP2011518828A/ja active Pending
- 2009-04-21 TW TW098113153A patent/TW200946113A/zh unknown
- 2009-04-22 AR ARP090101418A patent/AR071393A1/es not_active Application Discontinuation
- 2009-04-24 UY UY31786A patent/UY31786A1/es not_active Application Discontinuation
- 2009-04-24 CL CL2009000986A patent/CL2009000986A1/es unknown
-
2011
- 2011-01-14 US US13/006,984 patent/US20110105574A1/en not_active Abandoned
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