JP2011517455A

JP2011517455A - Ｃ（１０）エチルエステルおよびｃ（１０）シクロプロピルエステル置換タキサン

Ｃ（１０）エチルエステルおよびｃ（１０）シクロプロピルエステル置換タキサン Download PDF

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Publication number: JP2011517455A
Authority: JP; Japan
Prior art keywords: pharmaceutical composition; taxane; cancer; tumor; compound
Prior art date: 2008-03-31
Legal status : Pending

Application number

JP2011503034A

Other languages

English (en)

Japanese (ja)

Other versions

JP2011517455A5 (enExample

Inventor

フォン・ブ

ロバート・エイ・ホルトン

Current Assignee

Florida State University Research Foundation Inc

Original Assignee

Florida State University Research Foundation Inc

Priority date

2008-03-31

Filing date

2009-03-24

Publication date

2011-06-09

2009-03-24 Application filed by Florida State University Research Foundation Inc filed Critical Florida State University Research Foundation Inc

2011-06-09 Publication of JP2011517455A publication Critical patent/JP2011517455A/ja

2012-05-17 Publication of JP2011517455A5 publication Critical patent/JP2011517455A5/ja

Status Pending legal-status Critical Current

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229940123237 Taxane Drugs 0.000 title claims abstract description 66
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238000000034 method Methods 0.000 claims abstract description 49
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ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 claims description 69
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