JP2011515471A - 急性心筋梗塞を処置するための方法 - Google Patents

急性心筋梗塞を処置するための方法 Download PDF

Info

Publication number
JP2011515471A
JP2011515471A JP2011501845A JP2011501845A JP2011515471A JP 2011515471 A JP2011515471 A JP 2011515471A JP 2011501845 A JP2011501845 A JP 2011501845A JP 2011501845 A JP2011501845 A JP 2011501845A JP 2011515471 A JP2011515471 A JP 2011515471A
Authority
JP
Japan
Prior art keywords
gly
asp
seq
amino acid
glu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011501845A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011515471A5 (https=
Inventor
ランドルフ シー. ステアー,
マイケル アール. シェラー,
ジョン ディー. ワグスタッフ,
Original Assignee
オーソロジック コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by オーソロジック コーポレイション filed Critical オーソロジック コーポレイション
Publication of JP2011515471A publication Critical patent/JP2011515471A/ja
Publication of JP2011515471A5 publication Critical patent/JP2011515471A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4833Thrombin (3.4.21.5)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2011501845A 2008-03-26 2009-03-26 急性心筋梗塞を処置するための方法 Pending JP2011515471A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7083708P 2008-03-26 2008-03-26
US61/070,837 2008-03-26
US13795308P 2008-08-05 2008-08-05
US61/137,953 2008-08-05
PCT/US2009/001954 WO2009142679A2 (en) 2008-03-26 2009-03-26 Methods for treating acute myocardial infarction

Publications (2)

Publication Number Publication Date
JP2011515471A true JP2011515471A (ja) 2011-05-19
JP2011515471A5 JP2011515471A5 (https=) 2012-05-24

Family

ID=41170019

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011501845A Pending JP2011515471A (ja) 2008-03-26 2009-03-26 急性心筋梗塞を処置するための方法

Country Status (5)

Country Link
US (1) US20110105400A1 (https=)
EP (1) EP2268304A2 (https=)
JP (1) JP2011515471A (https=)
CA (1) CA2719940A1 (https=)
WO (1) WO2009142679A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016535059A (ja) * 2013-08-19 2016-11-10 クラウス・マイケル・シュミット 臓器保護のための液体麻酔薬と組み合わせた非麻酔性保護ガス

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009229395A1 (en) 2008-03-26 2009-10-01 The Board Of Regents, The University Of Texas System Method of treating degenerative diseases
US10220078B2 (en) 2014-06-11 2019-03-05 The Board Of Regents Of The University Of Texas System Methods of using thrombin derivatives to treat medulloblastoma

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004502739A (ja) * 2000-07-12 2004-01-29 ザ ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム トロンビン由来ペプチドを使用した治療法
JP2005519066A (ja) * 2002-01-16 2005-06-30 ザ ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム 心臓組織修復を促進するためのトロンビン由来ペプチド
JP2006510620A (ja) * 2002-11-18 2006-03-30 ザ・スクリプス・リサーチ・インステイチユート 心筋梗塞の治療方法
JP2006523685A (ja) * 2003-04-17 2006-10-19 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ 循環器疾患の治療のためのl−カルニチンの使用
JP2007277264A (ja) * 1995-06-07 2007-10-25 Ortho Pharmaceutical Corp エリトロポエチン受容体に結合する化合物およびペプチド
JP2007532483A (ja) * 2004-03-15 2007-11-15 ザ・スクリプス・リサーチ・インステイチユート 心筋梗塞の治療方法
WO2008036387A2 (en) * 2006-09-22 2008-03-27 Orthologic Corp. Method of treating endothelial dysfunction

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352664A (en) * 1986-10-31 1994-10-04 Board Of Regents, The University Of Texas System Thrombin derived polypeptides; compositions and methods for use
US6630572B1 (en) * 1986-10-31 2003-10-07 The Board Of Regents, University Of Texas Syatems Thrombin derived polypeptides: compositions and methods for use
US5244460A (en) * 1991-11-27 1993-09-14 The United States Of America As Represented By The Department Of Health And Human Services Method to foster myocardial blood vessel growth and improve blood flow to the heart
DE69633133T2 (de) * 1995-10-24 2005-07-28 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute TFPI-verwandte Peptide die das Wachstums von glatten Muskelzellen inhibieren
US5912229A (en) * 1996-03-01 1999-06-15 Novo Nordisk Als Use of a pharmaceutical composition comprising an appetite-suppressing peptide
US6197751B1 (en) * 1997-11-10 2001-03-06 The United States Of America As Represented By The Department Of Health And Human Services Thymosin α1 promotes tissue repair, angiogenesis and cell migration
US6033436A (en) * 1998-02-17 2000-03-07 Md3, Inc. Expandable stent
JP2002527401A (ja) * 1998-10-13 2002-08-27 カイロン コーポレイション Fgfの脈管形成的に有効な単位用量および投与方法
US6363938B2 (en) * 1998-12-22 2002-04-02 Angiotrax, Inc. Methods and apparatus for perfusing tissue and/or stimulating revascularization and tissue growth
US20020063763A1 (en) * 2000-11-29 2002-05-30 Mantell David Allen Apparatus and method for removing air bubbles from an ink jet printhead
DK1301196T3 (da) * 2000-07-19 2004-03-29 Univ Texas Stimulering af knoglevækst med peptidderivater af thrombin
EP1259598B1 (en) * 2000-07-20 2004-09-22 The Board of Regents, The University of Texas System Stimulation of cartilage growth with agonists of the non-proteolytically activated thrombin receptor
EP1414487B1 (en) * 2001-07-27 2006-06-07 Orthologic Corp. Use of thrombin-derived peptides for the therapy of chronic dermal ulcers
AU2003247848B2 (en) * 2002-07-02 2006-12-21 The Board Of Regents, The University Of Texas System Thrombin peptide derivative dimers
EP1539214A4 (en) * 2002-07-02 2008-01-02 Orthologic Corp Thrombin
PL1559431T3 (pl) * 2003-12-31 2007-10-31 Orthologic Corp Kompozycja farmaceutyczna dla pochodnych peptydu trombiny
BRPI0613284A2 (pt) * 2005-06-17 2010-12-28 Genentech Inc métodos de aceleração de cicatrização de ferida
EP2155234A1 (en) * 2007-04-10 2010-02-24 The Board of Regents,The University of Texas System Combination therapy for chronic dermal ulcers
US20100303793A1 (en) * 2007-04-10 2010-12-02 The Board Of Regents, The University Of Texas Syst Combination therapy for cardiac revascularization and cardiac repair
AU2009229399A1 (en) * 2008-03-26 2009-10-01 Orthologic Corp. Thrombin derived peptides for smooth muscle relaxation

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007277264A (ja) * 1995-06-07 2007-10-25 Ortho Pharmaceutical Corp エリトロポエチン受容体に結合する化合物およびペプチド
JP2004502739A (ja) * 2000-07-12 2004-01-29 ザ ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム トロンビン由来ペプチドを使用した治療法
JP2005519066A (ja) * 2002-01-16 2005-06-30 ザ ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム 心臓組織修復を促進するためのトロンビン由来ペプチド
JP2006510620A (ja) * 2002-11-18 2006-03-30 ザ・スクリプス・リサーチ・インステイチユート 心筋梗塞の治療方法
JP2006523685A (ja) * 2003-04-17 2006-10-19 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ 循環器疾患の治療のためのl−カルニチンの使用
JP2007532483A (ja) * 2004-03-15 2007-11-15 ザ・スクリプス・リサーチ・インステイチユート 心筋梗塞の治療方法
WO2008036387A2 (en) * 2006-09-22 2008-03-27 Orthologic Corp. Method of treating endothelial dysfunction

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6008008187; General Pharmacology (2000), Vol.35, No.5, p.249-254 *
JPN6013043254; 竹村元三他、医学のあゆみ,vol.205,p.799-803(2003) *
JPN6013043258; 冨原均他、医学のあゆみ,vol.167,p.546-550(1993) *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016535059A (ja) * 2013-08-19 2016-11-10 クラウス・マイケル・シュミット 臓器保護のための液体麻酔薬と組み合わせた非麻酔性保護ガス

Also Published As

Publication number Publication date
CA2719940A1 (en) 2009-11-26
WO2009142679A3 (en) 2010-01-14
AU2009249629A1 (en) 2009-11-26
WO2009142679A2 (en) 2009-11-26
EP2268304A2 (en) 2011-01-05
US20110105400A1 (en) 2011-05-05

Similar Documents

Publication Publication Date Title
CN103648518B (zh) 局部缺血的组合治疗
US20190365845A1 (en) Methods for performing a coronary artery bypass graft procedure
JP6741642B2 (ja) くも膜下出血および虚血の治療法
US11141456B2 (en) Therapeutic compositions including frataxin, lactoferrin, and mitochondrial energy generating enzymes, and uses thereof
JP2019069942A (ja) ペプチド治療薬およびその使用方法
JP2020114880A (ja) 虚血/再灌流障害に続くノーリフローの予防又は処置方法
JP2017025093A (ja) 血管閉塞傷害の予防または治療方法
JPS6322026A (ja) 医薬組成物
JP6411215B2 (ja) 虚血傷害を治療するためのシステアミンおよび/またはシスタミン
JP2019052158A (ja) カルジオリピン標的化ペプチドはベータアミロイドオリゴマー毒性を阻害する
US20250129184A1 (en) Targeted anticoagulant
JP2011515471A (ja) 急性心筋梗塞を処置するための方法
AU2009249629B2 (en) Methods for treating acute myocardial infarction
JP2017203036A (ja) 芳香族カチオン性ペプチド及びその使用
CA2632697A1 (en) Treatment of mitochondria-related diseases and improvement of age-related metabolic deficits
JP2012522782A (ja) 医薬のためのプラットフォームとしての、少なくとも1つの保護されたチオール領域を有するpeg−アルブミン組成物
ES2461195T3 (es) Fructosamina oxidasa: antagonistas e inhibidores
CN115957295A (zh) 一类订书肽化合物在制备治疗肝纤维化药物中的应用
AU2017210562A1 (en) Methods for performing a coronary artery bypass graft procedure

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120323

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20120323

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130226

A711 Notification of change in applicant

Free format text: JAPANESE INTERMEDIATE CODE: A711

Effective date: 20130422

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130829

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20131120

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20131127

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20131220

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20140106

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140129

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20140129

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20140714