CA2719940A1 - Methods for treating acute myocardial infarction - Google Patents

Methods for treating acute myocardial infarction Download PDF

Info

Publication number
CA2719940A1
CA2719940A1 CA2719940A CA2719940A CA2719940A1 CA 2719940 A1 CA2719940 A1 CA 2719940A1 CA 2719940 A CA2719940 A CA 2719940A CA 2719940 A CA2719940 A CA 2719940A CA 2719940 A1 CA2719940 A1 CA 2719940A1
Authority
CA
Canada
Prior art keywords
gly
asp
seq
glu
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2719940A
Other languages
English (en)
French (fr)
Inventor
Randolph C. Steer
Michael R. Sheller
John D. Wagstaff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Original Assignee
Orthologic Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orthologic Corp filed Critical Orthologic Corp
Publication of CA2719940A1 publication Critical patent/CA2719940A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2719940A 2008-03-26 2009-03-26 Methods for treating acute myocardial infarction Abandoned CA2719940A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7083708P 2008-03-26 2008-03-26
US61/070,837 2008-03-26
US13795308P 2008-08-05 2008-08-05
US61/137,953 2008-08-05
PCT/US2009/001954 WO2009142679A2 (en) 2008-03-26 2009-03-26 Methods for treating acute myocardial infarction

Publications (1)

Publication Number Publication Date
CA2719940A1 true CA2719940A1 (en) 2009-11-26

Family

ID=41170019

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2719940A Abandoned CA2719940A1 (en) 2008-03-26 2009-03-26 Methods for treating acute myocardial infarction

Country Status (5)

Country Link
US (1) US20110105400A1 (https=)
EP (1) EP2268304A2 (https=)
JP (1) JP2011515471A (https=)
CA (1) CA2719940A1 (https=)
WO (1) WO2009142679A2 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2280722A2 (en) 2008-03-26 2011-02-09 Orthologic Corp. Method of treating degenerative diseases
JP6502350B2 (ja) * 2013-08-19 2019-04-17 クラウス・マイケル・シュミット 臓器保護のための液体麻酔薬と組み合わせた非麻酔性保護ガス
US10220078B2 (en) 2014-06-11 2019-03-05 The Board Of Regents Of The University Of Texas System Methods of using thrombin derivatives to treat medulloblastoma

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352664A (en) * 1986-10-31 1994-10-04 Board Of Regents, The University Of Texas System Thrombin derived polypeptides; compositions and methods for use
US6630572B1 (en) * 1986-10-31 2003-10-07 The Board Of Regents, University Of Texas Syatems Thrombin derived polypeptides: compositions and methods for use
US5244460A (en) * 1991-11-27 1993-09-14 The United States Of America As Represented By The Department Of Health And Human Services Method to foster myocardial blood vessel growth and improve blood flow to the heart
CA2223833C (en) * 1995-06-07 2010-12-21 Nicholas C. Wrighton Compounds and peptides that bind to the erythropoietin receptor
AU719366B2 (en) * 1995-10-24 2000-05-04 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Novel peptide
US5912229A (en) * 1996-03-01 1999-06-15 Novo Nordisk Als Use of a pharmaceutical composition comprising an appetite-suppressing peptide
US6197751B1 (en) * 1997-11-10 2001-03-06 The United States Of America As Represented By The Department Of Health And Human Services Thymosin α1 promotes tissue repair, angiogenesis and cell migration
US6033436A (en) * 1998-02-17 2000-03-07 Md3, Inc. Expandable stent
US20040214836A1 (en) * 1998-05-29 2004-10-28 Cheresh David A. Method of treatment of myocardial infarction
US20030130209A1 (en) * 1999-12-22 2003-07-10 Cheresh David A. Method of treatment of myocardial infarction
JP2002527401A (ja) * 1998-10-13 2002-08-27 カイロン コーポレイション Ｆｇｆの脈管形成的に有効な単位用量および投与方法
US6363938B2 (en) * 1998-12-22 2002-04-02 Angiotrax, Inc. Methods and apparatus for perfusing tissue and/or stimulating revascularization and tissue growth
US20020063763A1 (en) * 2000-11-29 2002-05-30 Mantell David Allen Apparatus and method for removing air bubbles from an ink jet printhead
TWI257307B (en) * 2000-07-12 2006-07-01 Orthologic Corp Pharmaceutical composition for cardiac tissue repair
ATE254925T1 (de) * 2000-07-19 2003-12-15 Univ Texas Stimulierung des knochenwachstums mit peptidderivaten von thrombin
AU7356101A (en) * 2000-07-20 2002-02-05 Univ Texas Stimulation of cartilage growth with agonists of the non-proteolytically activated thrombin receptor
ES2271216T3 (es) * 2001-07-27 2007-04-16 Orthologic Corp. Uso de los peptidos derivados de la trombina para la terapia de las ulceras dermicas cronicas.
ATE504311T1 (de) * 2002-01-16 2011-04-15 Capstone Therapeutics Corp Thrombin-derivierten peptiden zur förderung von herzgewebsreparatur
AU2003256343B2 (en) * 2002-07-02 2006-12-21 Orthologic Corp. Thrombin peptide derivatives
DE60313982T2 (de) * 2002-07-02 2008-01-17 Orthologic Corp., Tempe Dimere von thrombinpeptidderivaten
ITRM20030178A1 (it) * 2003-04-17 2004-10-18 Sigma Tau Ind Farmaceuti Uso della l-carnitina per il trattamento di patologie cardiovascolari.
CN1913917B (zh) * 2003-12-31 2012-02-01 正统逻辑公司 凝血酶肽衍生物的药物组合物
AU2006259408A1 (en) * 2005-06-17 2006-12-28 Genentech, Inc. Use of VEGF for wound healing
JP2010504336A (ja) * 2006-09-22 2010-02-12 オーソロジック コーポレイション 血管内皮機能不全を治療する方法
EP2155234A1 (en) * 2007-04-10 2010-02-24 The Board of Regents,The University of Texas System Combination therapy for chronic dermal ulcers
WO2008124173A1 (en) * 2007-04-10 2008-10-16 The Board Of Regents, The University Of Texas System Combination therapy for cardiac revascularization and cardiac repair
CA2722621A1 (en) * 2008-03-26 2009-10-01 Orthologic Corp. Thrombin derived peptides for smooth muscle relaxation

Also Published As

Publication number Publication date
WO2009142679A3 (en) 2010-01-14
WO2009142679A2 (en) 2009-11-26
EP2268304A2 (en) 2011-01-05
AU2009249629A1 (en) 2009-11-26
JP2011515471A (ja) 2011-05-19
US20110105400A1 (en) 2011-05-05

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20140108

FZDE Discontinued

Effective date: 20160329