JP2011512543A5 - - Google Patents

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JP2011512543A5
JP2011512543A5 JP2010547673A JP2010547673A JP2011512543A5 JP 2011512543 A5 JP2011512543 A5 JP 2011512543A5 JP 2010547673 A JP2010547673 A JP 2010547673A JP 2010547673 A JP2010547673 A JP 2010547673A JP 2011512543 A5 JP2011512543 A5 JP 2011512543A5
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wavelength
radiation
imaging
living
light
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JP2011512543A (ja
JP5496115B2 (ja
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JP2010547673A 2008-02-18 2009-02-03 紫外放射を用いた生細胞の３次元画像化 Expired - Fee Related JP5496115B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/032,959 US8143600B2 (en) 2008-02-18 2008-02-18 3D imaging of live cells with ultraviolet radiation
US12/032,959 2008-02-18
PCT/US2009/032969 WO2009105331A2 (en) 2008-02-18 2009-02-03 3d imaging of live cells with utraviolet radiation

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JP2014040069A Division JP5908010B2 (ja) 2008-02-18 2014-03-03 紫外放射を用いた生細胞の３次元画像化

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JP2011512543A JP2011512543A (ja) 2011-04-21
JP2011512543A5 true JP2011512543A5 (zh) 2012-03-08
JP5496115B2 JP5496115B2 (ja) 2014-05-21

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JP2010547673A Expired - Fee Related JP5496115B2 (ja) 2008-02-18 2009-02-03 紫外放射を用いた生細胞の３次元画像化
JP2014040069A Active JP5908010B2 (ja) 2008-02-18 2014-03-03 紫外放射を用いた生細胞の３次元画像化

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US (2) US8143600B2 (zh)
EP (1) EP2247918A4 (zh)
JP (2) JP5496115B2 (zh)
CN (1) CN102007369B (zh)
AU (1) AU2009215714B2 (zh)
CA (2) CA2715623C (zh)
WO (1) WO2009105331A2 (zh)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7344225B2 (ja) 2018-10-26 2023-09-13 ケーエルエー コーポレイション 結像系設計における微分干渉コントラストの走査

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120077206A1 (en) 2003-07-12 2012-03-29 Accelr8 Technology Corporation Rapid Microbial Detection and Antimicrobial Susceptibility Testing
CA2532414C (en) 2003-07-12 2017-03-14 Accelr8 Technology Corporation Sensitive and rapid biodetection
US9557217B2 (en) 2007-02-13 2017-01-31 Bti Holdings, Inc. Universal multidetection system for microplates
CA2691451C (en) 2007-06-21 2015-03-24 Sara H. Fan Instrument and receptacles for performing processes
WO2010022330A2 (en) * 2008-08-21 2010-02-25 University Of Florida Research Foundation, Inc. Differential laser-induced perturbation (dlip) for bioimaging and chemical sensing
JP4288323B1 (ja) * 2008-09-13 2009-07-01 独立行政法人科学技術振興機構 顕微鏡装置及びそれを用いた蛍光観察方法
US8368882B2 (en) * 2009-01-30 2013-02-05 Gen-Probe Incorporated Systems and methods for detecting a signal and applying thermal energy to a signal transmission element
KR20110056168A (ko) * 2009-11-20 2011-05-26 삼성전자주식회사 미세유동장치, 광조사장치 및 이를 포함하는 미세유동시스템과 그 구동방법
US8982182B2 (en) * 2010-03-01 2015-03-17 Apple Inc. Non-uniform spatial resource allocation for depth mapping
TWI421618B (zh) * 2010-04-09 2014-01-01 Ind Tech Res Inst 景深擴展之投影系統及影像處理方法
US8867803B2 (en) * 2010-04-20 2014-10-21 Eric J. Seibel Optical projection tomography microscopy (OPTM) for large specimen sizes
US20120181450A1 (en) * 2011-01-18 2012-07-19 Electronics And Telecommunications Research Institute Method and apparatus for detecting bio material using photoelectric conversion device, and method for manufacturing photoelectric conversion device
US8718948B2 (en) 2011-02-24 2014-05-06 Gen-Probe Incorporated Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector
US10254204B2 (en) 2011-03-07 2019-04-09 Accelerate Diagnostics, Inc. Membrane-assisted purification
EP2683831B1 (en) 2011-03-07 2015-09-23 Accelerate Diagnostics, Inc. Rapid cell purification systems
CN102499639A (zh) * 2011-10-24 2012-06-20 西安电子科技大学 联合成像的光学投影断层成像装置及方法
US20130182081A1 (en) * 2012-01-12 2013-07-18 Gary Greenberg Real-Time Stereo 3D Digital/Video Imaging in a Light Microscope Using a Single Lens and a Single Camera
DE102012201003A1 (de) * 2012-01-24 2013-07-25 Carl Zeiss Microscopy Gmbh Mikroskop und Verfahren für die hochauflösende 3-D Fluoreszenzmikroskopie
CN102589694B (zh) * 2012-02-02 2014-02-26 麦克奥迪实业集团有限公司 一种多光谱显微图像的获取装置
GB201204004D0 (en) * 2012-03-07 2012-04-18 Imp Innovations Ltd Multiplexed optical projection tomography
CN102743159B (zh) * 2012-07-26 2015-03-04 中国科学院自动化研究所 光学投影断层成像系统
DE102012108158B4 (de) 2012-09-03 2016-03-17 Johann Wolfgang Goethe-Universität Kapillarzelle, Anordnung und Verfahren zur Aufnahme, zur Positionierung und zur Untersuchung einer mikroskopischen Probe
US9766121B2 (en) * 2012-09-28 2017-09-19 Intel Corporation Mobile device based ultra-violet (UV) radiation sensing
CN103110425A (zh) * 2013-03-11 2013-05-22 西安电子科技大学 一种联合成像的锥束x射线发光断层成像系统及其方法
US9677109B2 (en) 2013-03-15 2017-06-13 Accelerate Diagnostics, Inc. Rapid determination of microbial growth and antimicrobial susceptibility
DK3004838T3 (da) * 2013-05-28 2022-06-20 Chemometec As Billeddannende cytometer
US20160131583A1 (en) * 2013-06-03 2016-05-12 Ventana Medical Systems, Inc. Fluorescence imaging system for tissue detection
WO2014194944A1 (de) * 2013-06-05 2014-12-11 Ev Group E. Thallner Gmbh Messeinrichtung und verfahren zur ermittlung einer druckkarte
DE102013019951B4 (de) * 2013-11-27 2023-06-15 Carl Zeiss Microscopy Gmbh Lichtmikroskop und Mikroskopieverfahren zum Untersuchen mehrerer mikroskopischer Objekte
KR101506099B1 (ko) * 2013-12-13 2015-03-26 고려대학교 산학협력단 파동의 투과 특성을 향상시키는 방법 및 무작위적 매질에 파동을 입사시켜 기 설정된 기능을 수행하는 장치
CN103695305B (zh) * 2013-12-18 2016-06-22 麦克奥迪实业集团有限公司 一种用于自动显微镜的灰度摄像头及细胞综合分析装置
CN103837461B (zh) * 2014-01-16 2016-08-24 麦克奥迪实业集团有限公司 一种灰度摄像头及具有高效率照明的细胞综合分析装置
CN106170687B (zh) * 2014-04-17 2019-10-15 深圳迈瑞生物医疗电子股份有限公司 粒子分析仪及其分析操作结果回退方法和装置
CN104036545A (zh) * 2014-06-27 2014-09-10 嘉善天慧光电科技有限公司 一种便携式自适应图像三维重建仪的光源结构
KR101688873B1 (ko) * 2014-09-03 2016-12-23 고려대학교 산학협력단 광 간섭 단층 영상 촬영 장치
WO2016094521A1 (en) * 2014-12-09 2016-06-16 The Texas A&M University System Mobile polarized-imaging platform for point-of-care diagnostics
US10852291B2 (en) 2015-02-03 2020-12-01 University Of Washington Fluidic device and methods of use for processing tissue for pathology
JP6585728B2 (ja) * 2015-02-23 2019-10-02 リ−コール，インコーポレイティド 生検標本蛍光撮像装置および方法
US10253355B2 (en) 2015-03-30 2019-04-09 Accelerate Diagnostics, Inc. Instrument and system for rapid microorganism identification and antimicrobial agent susceptibility testing
US10023895B2 (en) 2015-03-30 2018-07-17 Accelerate Diagnostics, Inc. Instrument and system for rapid microogranism identification and antimicrobial agent susceptibility testing
US9799113B2 (en) * 2015-05-21 2017-10-24 Invicro Llc Multi-spectral three dimensional imaging system and method
US10379048B2 (en) 2015-06-26 2019-08-13 Li-Cor, Inc. Fluorescence biopsy specimen imager and methods
EP3338086A4 (en) * 2015-12-30 2018-11-14 VisionGate, Inc. System and method for automated detection and monitoring of dysplasia and administration of chemoprevention
US11069054B2 (en) 2015-12-30 2021-07-20 Visiongate, Inc. System and method for automated detection and monitoring of dysplasia and administration of immunotherapy and chemotherapy
WO2017136476A1 (en) * 2016-02-01 2017-08-10 Jaiswal Supriya Extreme ultraviolet radiation in genomic sequencing and other applications
WO2017151978A1 (en) * 2016-03-02 2017-09-08 Arizona Boad Of Regents On Behalf Of Arizona State University Live-cell computed tomography
WO2017184940A1 (en) 2016-04-21 2017-10-26 Li-Cor, Inc. Multimodality multi-axis 3-d imaging
WO2017223378A1 (en) 2016-06-23 2017-12-28 Li-Cor, Inc. Complementary color flashing for multichannel image presentation
CN106525845B (zh) 2016-10-11 2023-11-03 聚束科技（北京）有限公司 一种带电粒子束系统、光电联合探测系统及方法
US11506877B2 (en) 2016-11-10 2022-11-22 The Trustees Of Columbia University In The City Of New York Imaging instrument having objective axis and light sheet or light beam projector axis intersecting at less than 90 degrees
WO2018098162A1 (en) 2016-11-23 2018-05-31 Li-Cor, Inc. Motion-adaptive interactive imaging method
WO2018160998A1 (en) 2017-03-02 2018-09-07 Arizona Board Of Regents On Behalf Of Arizona State University Live-cell computed tomography
CN106880340B (zh) * 2017-03-09 2020-03-13 广州永士达医疗科技有限责任公司 一种oct设备成像性能评价装置及其使用方法
US10386301B2 (en) * 2017-04-25 2019-08-20 Li-Cor, Inc. Top-down and rotational side view biopsy specimen imager and methods
EP3658911A4 (en) 2017-07-27 2020-08-19 E-Flux LLC METHODS, SYSTEMS AND DEVICES FOR IN-SITU MEASUREMENT
WO2019034328A1 (en) 2017-08-15 2019-02-21 Siemens Healthcare Gmbh IDENTIFYING THE QUALITY OF CELLULAR IMAGES ACQUIRED USING DIGITAL HOLOGRAPHIC MICROSCOPY USING CONVOLUTIONAL NEURAL NETWORKS
WO2019090290A1 (en) * 2017-11-06 2019-05-09 University Of Washington Biopsy sample manipulation and imaging system and methods for use
EP3752815A4 (en) 2018-02-16 2021-11-03 The Regents of The University of California SYSTEMS, DEVICES AND METHODS FOR THREE-DIMENSIONAL IMAGING OF MOVING PARTICLES
US11067476B2 (en) 2018-02-21 2021-07-20 Schneider Gmbh & Co. Kg Apparatus and method for measuring at least one optically effective object
DE102018001385A1 (de) * 2018-02-21 2019-08-22 Schneider Gmbh & Co. Kg Vorrichtung und Verfahren zum Vermessen mindestens eines optisch wirksamen Gegenstands
WO2019209345A1 (en) * 2018-04-27 2019-10-31 Hewlett-Packard Development Company, L.P. Three-dimensional volume imaging
US11686680B2 (en) * 2018-05-23 2023-06-27 Fundació Institut De Ciències Fotôniques Apparatus for exploring an optical property of a sample
US11403832B2 (en) 2018-10-03 2022-08-02 Hewlett-Packard Development Company, L.P. Modeling rotating objects
JP2022510388A (ja) * 2018-12-04 2022-01-26 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア タンパク質結晶の高コントラストイメージングのための携帯型ｕｖホログラフィック顕微鏡
CN109459846B (zh) * 2018-12-25 2020-02-14 西安交通大学 一种用于捕获目标物运动全过程的显微成像装置及方法
US10871640B2 (en) * 2019-02-15 2020-12-22 Perkinelmer Cellular Technologies Germany Gmbh Methods and systems for automated imaging of three-dimensional objects
RU2725798C1 (ru) * 2019-04-01 2020-07-06 Илья Николаевич Соломадин Способ идентификации клеток крови
JPWO2021033750A1 (zh) * 2019-08-21 2021-02-25
WO2021072408A1 (en) * 2019-10-10 2021-04-15 Georgia Tech Research Corporation Label-free hematology and histopathology analysis using deep-ultraviolet microscopy
JP2023501769A (ja) * 2019-11-22 2023-01-19 パーティクル・メージャーリング・システムズ・インコーポレーテッド 干渉粒子検出及び小サイズ寸法を有する粒子の検出のための高度なシステム及び方法
JP2023541449A (ja) * 2020-09-14 2023-10-02 シンギュラー・ゲノミクス・システムズ・インコーポレイテッド 多次元撮像のための方法およびシステム
US11744242B2 (en) * 2020-09-17 2023-09-05 Drsignal Biotechnology Co., Ltd. Living body specimen transport device
DE102021211596A1 (de) * 2020-10-14 2022-04-14 Emage Vision PTE, Ltd. Analyse- und nachverfolgungssystem für fehler an kontaktlinsen
JP7432182B2 (ja) 2020-10-18 2024-02-16 エイアイエックスメド・インコーポレイテッド 細胞病理検査における細胞診画像を取得する方法およびシステム
JP7482583B2 (ja) 2021-01-27 2024-05-14 Ｊｆｅテクノリサーチ株式会社 指掌紋撮影装置、指掌紋撮影方法及び検体の検査方法
EP4067866A1 (en) * 2021-04-01 2022-10-05 Leica Microsystems CMS GmbH Imaging system and method for imaging biological samples
CN113777767B (zh) * 2021-09-14 2022-06-10 北京大学长三角光电科学研究院 一种快速连续旋转样品的光学层析显微成像系统及其方法
CN115032780B (zh) * 2022-05-25 2024-01-26 北京理工大学 组织病理图片的快速处理系统及其工作方法

Family Cites Families (119)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470373A (en) 1966-10-18 1969-09-30 Litton Systems Inc Method for analysis and identification of biologic entities by phosphorescence
US3497690A (en) 1967-09-21 1970-02-24 Bausch & Lomb Method and apparatus for classifying biological cells by measuring the size and fluorescent response thereof
US3598471A (en) 1968-11-22 1971-08-10 Corning Glass Works Optical contrast enhancement system
US3657537A (en) 1970-04-03 1972-04-18 Bausch & Lomb Computerized slit-scan cyto-fluorometer for automated cell recognition
US3999047A (en) 1972-09-05 1976-12-21 Green James E Method and apparatus utilizing color algebra for analyzing scene regions
US3960449A (en) 1975-06-05 1976-06-01 The Board Of Trustees Of Leland Stanford Junior University Measurement of angular dependence of scattered light in a flowing stream
US4183623A (en) 1977-10-11 1980-01-15 Haines Kenneth A Tomographic cross-sectional imaging using incoherent optical processing
US4293221A (en) 1979-04-17 1981-10-06 Research Corporation Multidimensional slit-scan flow system
US4360885A (en) 1980-01-02 1982-11-23 Edgar Albert D Micro-optical tomography
US4702598A (en) 1985-02-25 1987-10-27 Research Corporation Flow cytometer
US5281517A (en) 1985-11-04 1994-01-25 Cell Analysis Systems, Inc. Methods for immunoploidy analysis
US4873653A (en) 1986-04-09 1989-10-10 Carl-Zeiss-Stiftung Microscope system for providing three-dimensional resolution
US4786165A (en) 1986-07-10 1988-11-22 Toa Medical Electronics Co., Ltd. Flow cytometry and apparatus therefor
US4858128A (en) 1986-08-11 1989-08-15 General Electric Company View-to-view image correction for object motion
KR970007077B1 (ko) 1987-03-13 1997-05-02 코울터 일렉트로닉스 인커퍼레이티드 광산란 기술을 이용한 다중-부분식별 분석 방법
US5034613A (en) 1989-11-14 1991-07-23 Cornell Research Foundation, Inc. Two-photon laser microscopy
US5141609A (en) 1990-11-16 1992-08-25 The Trustees Of The Leland Stanford Junior University Method and device employing time-delayed integration for detecting sample components after separation
US5936731A (en) * 1991-02-22 1999-08-10 Applied Spectral Imaging Ltd. Method for simultaneous detection of multiple fluorophores for in situ hybridization and chromosome painting
JP3084295B2 (ja) 1991-02-27 2000-09-04 シスメックス株式会社 フローイメージサイトメータ
US5117466A (en) 1991-04-30 1992-05-26 The United States Of America As Represented By The United States Department Of Energy Integrated fluorescence analysis system
JPH04337446A (ja) 1991-05-15 1992-11-25 Hitachi Ltd 微粒子計測方法、定量方法および微粒子計測装置
US5548395A (en) 1991-09-20 1996-08-20 Toa Medical Electronics Co., Ltd. Particle analyzer
US5333164A (en) 1991-12-11 1994-07-26 General Electric Company Method and apparatus for acquiring and processing only a necessary volume of radon data consistent with the overall shape of the object for efficient three dimensional image reconstruction
GB9218482D0 (en) 1992-09-01 1992-10-14 Dixon Arthur E Apparatus and method for scanning laser imaging of macroscopic samples
US5390023A (en) * 1992-06-03 1995-02-14 Zygo Corporation Interferometric method and apparatus to measure surface topography
JP3327948B2 (ja) 1992-06-09 2002-09-24 オリンパス光学工業株式会社 光学像再構成装置
US5390226A (en) 1992-07-02 1995-02-14 General Electric Company Method and apparatus for pre-processing cone beam projection data for exact three dimensional computer tomographic image reconstruction of a portion of an object
US5312535A (en) 1992-07-17 1994-05-17 Beckman Instruments, Inc. Capillary electrophoresis detection
EP0814334B1 (en) * 1992-07-31 2004-09-29 Fuji Photo Film Co., Ltd. Method and apparatus for obtaining three-dimensional information of samples
US5332905A (en) * 1992-08-26 1994-07-26 Atto Instruments, Inc. Apparatus and method for multiple emission ratio photometry and multiple emission ratio imaging
US6159686A (en) 1992-09-14 2000-12-12 Sri International Up-converting reporters for biological and other assays
US6026174A (en) 1992-10-14 2000-02-15 Accumed International, Inc. System and method for automatically detecting malignant cells and cells having malignancy-associated changes
JPH06259533A (ja) * 1993-03-05 1994-09-16 Olympus Optical Co Ltd 光学像再構成装置
US5402460A (en) 1993-08-02 1995-03-28 University Of Washington Three-dimensional microtomographic analysis system
EP0752099A1 (en) * 1994-02-09 1997-01-08 Abbott Laboratories Diagnostic flow cell device
US6215587B1 (en) 1994-02-14 2001-04-10 Robert R. Alfano Microscope imaging inside highly scattering media
JPH07286953A (ja) 1994-04-19 1995-10-31 Toa Medical Electronics Co Ltd イメージングフローサイトメータ
US5552605A (en) 1994-11-18 1996-09-03 Picker International, Inc. Motion correction based on reprojection data
FI98765C (fi) 1995-01-16 1997-08-11 Erkki Soini Virtaussytometrinen menetelmä ja laite
US5539800A (en) 1995-03-24 1996-07-23 The Regents Of The University Of California, Office Of Technology Transfer Pseudolocal tomography
US5710429A (en) 1995-04-06 1998-01-20 Alfano; Robert R. Ultrafast optical imaging of objects in or behind scattering media
US5582705A (en) 1995-05-19 1996-12-10 Iowa State University Research Foundation, Inc. Multiplexed capillary electrophoresis system
EP1426381A1 (en) 1995-10-02 2004-06-09 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES An epithelial protein and DNA thereof for use in early cancer detection
US5835617A (en) 1996-01-18 1998-11-10 Hamamatsu Photonics K.K. Optical computer tomographic apparatus and image reconstruction method using optical computer tomography
US6078681A (en) 1996-03-18 2000-06-20 Marine Biological Laboratory Analytical imaging system and process
JP3640461B2 (ja) 1996-04-03 2005-04-20 シスメックス株式会社 粒子分析装置
US6038067A (en) 1996-05-23 2000-03-14 The Regents Of The University Of California Scanning computed confocal imager
US5880838A (en) 1996-06-05 1999-03-09 California Institute Of California System and method for optically measuring a structure
DE69730053T2 (de) 1996-11-29 2005-07-21 Imaging Diagnostic System, Inc., Plantation Verfahren zur abbildung eines körpers mittels abtastung durch eine laser-bilderzeugungs-vorrichtung
US5760901A (en) 1997-01-28 1998-06-02 Zetetic Institute Method and apparatus for confocal interference microscopy with background amplitude reduction and compensation
US6091983A (en) 1997-02-07 2000-07-18 Alfano; Robert R. Imaging of objects in turbid media based upon the preservation of polarized luminescence emitted from contrast agents
JPH10260131A (ja) 1997-03-19 1998-09-29 Seitai Hikarijoho Kenkyusho:Kk 光計測装置
US6540895B1 (en) 1997-09-23 2003-04-01 California Institute Of Technology Microfabricated cell sorter for chemical and biological materials
US6037579A (en) 1997-11-13 2000-03-14 Biophotonics Information Laboratories, Ltd. Optical interferometer employing multiple detectors to detect spatially distorted wavefront in imaging of scattering media
JP2001523830A (ja) 1997-11-19 2001-11-27 ユニバーシティ オブ ワシントン 高処理能力光学スキャナー
US6251615B1 (en) 1998-02-20 2001-06-26 Cell Analytics, Inc. Cell analysis methods
US6291824B1 (en) 1998-04-13 2001-09-18 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Apparatus and method for high-bandwidth optical tomography
US6248988B1 (en) 1998-05-05 2001-06-19 Kla-Tencor Corporation Conventional and confocal multi-spot scanning optical microscope
US6529614B1 (en) 1998-08-05 2003-03-04 California Institute Of Technology Advanced miniature processing handware for ATR applications
JP2000121550A (ja) 1998-10-16 2000-04-28 Japan Science & Technology Corp ヘテロダイン検波による生体試料の画像検出方法及びその装置
US6640014B1 (en) 1999-01-22 2003-10-28 Jeffrey H. Price Automatic on-the-fly focusing for continuous image acquisition in high-resolution microscopy
US6975400B2 (en) 1999-01-25 2005-12-13 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US6249341B1 (en) 1999-01-25 2001-06-19 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US6473176B2 (en) 1999-01-25 2002-10-29 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US6608682B2 (en) 1999-01-25 2003-08-19 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US7450229B2 (en) 1999-01-25 2008-11-11 Amnis Corporation Methods for analyzing inter-cellular phenomena
DE19931954A1 (de) 1999-07-10 2001-01-11 Leica Microsystems Beleuchtungseinrichtung für ein DUV-Mikroskop
US6239871B1 (en) 1999-08-24 2001-05-29 Waters Investments Limited Laser induced fluorescence capillary interface
DE19949029C2 (de) * 1999-10-11 2002-11-21 Innovatis Gmbh Verfahren und Vorrichtung zur Charakterisierung einer Kulturflüssigkeit
US7003143B1 (en) 1999-11-02 2006-02-21 Hewitt Charles W Tomographic microscope for high resolution imaging and method of analyzing specimens
US6775399B1 (en) 1999-11-17 2004-08-10 Analogic Corporation ROI segmentation image processing system
US6365367B1 (en) 1999-12-06 2002-04-02 Cellomics, Inc. Environmental chamber for the analysis of live cells
CZ20021853A3 (cs) * 1999-12-09 2002-11-13 Sankyo Company, Limited Způsob testování účinku látky, polynukleotid, DNA, protilátka, souprava pro testování, pouľití polynukleotidu, pouľití polypeptidu, pouľití protilátky, RNA a terapeutické činidlo
JP4994560B2 (ja) 2000-08-25 2012-08-08 アムニス コーポレイション 細胞などの小さな移動物体の速度測定
AU1576401A (en) 2000-10-27 2002-05-06 Praelux Inc Method and apparatus for screening chemical compounds
US20060023219A1 (en) 2001-03-28 2006-02-02 Meyer Michael G Optical tomography of small objects using parallel ray illumination and post-specimen optical magnification
US6519355B2 (en) 2001-03-28 2003-02-11 Alan C. Nelson Optical projection imaging system and method for automatically detecting cells having nuclear and cytoplasmic densitometric features associated with disease
US6944322B2 (en) 2001-03-28 2005-09-13 Visiongate, Inc. Optical tomography of small objects using parallel ray illumination and post-specimen optical magnification
US6591003B2 (en) 2001-03-28 2003-07-08 Visiongate, Inc. Optical tomography of small moving objects using time delay and integration imaging
US6522775B2 (en) * 2001-03-28 2003-02-18 Alan C. Nelson Apparatus and method for imaging small objects in a flow stream using optical tomography
GB0112392D0 (en) 2001-05-22 2001-07-11 Medical Res Council Optical imaging appartus and associated specimen support means
WO2003014795A1 (en) 2001-08-06 2003-02-20 Bioview Ltd. Image focusing in fluorescent imaging
US6741730B2 (en) 2001-08-10 2004-05-25 Visiongate, Inc. Method and apparatus for three-dimensional imaging in the fourier domain
US6636623B2 (en) 2001-08-10 2003-10-21 Visiongate, Inc. Optical projection imaging system and method for automatically detecting cells with molecular marker compartmentalization associated with malignancy and disease
US6842297B2 (en) 2001-08-31 2005-01-11 Cdm Optics, Inc. Wavefront coding optics
EP1436658B1 (de) * 2001-09-11 2008-06-18 Leica Microsystems CMS GmbH Verfahren und vorrichtung zur optischen untersuchung eines objektes
US6850587B1 (en) 2001-10-24 2005-02-01 Analogic Corporation Reprojection-based three-dimensional image reconstruction
US7283253B2 (en) 2002-03-13 2007-10-16 Applied Precision, Llc Multi-axis integration system and method
US7811825B2 (en) 2002-04-19 2010-10-12 University Of Washington System and method for processing specimens and images for optical tomography
US7260253B2 (en) 2002-04-19 2007-08-21 Visiongate, Inc. Method for correction of relative object-detector motion between successive views
US20050085708A1 (en) 2002-04-19 2005-04-21 University Of Washington System and method for preparation of cells for 3D image acquisition
US7197355B2 (en) 2002-04-19 2007-03-27 Visiongate, Inc. Variable-motion optical tomography of small objects
US7738945B2 (en) * 2002-04-19 2010-06-15 University Of Washington Method and apparatus for pseudo-projection formation for optical tomography
JP2005523717A (ja) * 2002-05-01 2005-08-11 マサチューセッツ インスティテュート オブ テクノロジー 生化学的過程の迅速なスクリーニングおよび分析のための微小発酵槽
JP2005524833A (ja) * 2002-05-03 2005-08-18 イムニベスト・コーポレイション 分析細胞イメージング用のデバイスおよび方法
US6697508B2 (en) 2002-05-10 2004-02-24 Visiongate, Inc. Tomographic reconstruction of small objects using a priori knowledge
US6770893B2 (en) * 2002-05-13 2004-08-03 Visiongate, Inc. Method and apparatus for emission computed tomography using temporal signatures
US20040008515A1 (en) 2002-06-11 2004-01-15 Applied Precision Fluorescence illumination optimization for three-dimensional microscopy
US6894779B2 (en) 2002-08-23 2005-05-17 Coulter International Corp. Apparatus for detecting back-scatter in a laser-based blood analysis system
US7274809B2 (en) 2002-08-29 2007-09-25 Perceptronix Medical, Inc. And British Columbia Cancer Agency Computerized methods and systems related to the detection of malignancy-associated changes (MAC) to detect cancer
CA2490578A1 (en) 2002-08-30 2004-03-11 Medical Research Council Optical projection tomography
JP2006518050A (ja) 2003-02-18 2006-08-03 オクラホマ　メディカル　リサーチ　ファウンデーション 焦点深度拡張顕微鏡法
WO2004073501A2 (en) 2003-02-20 2004-09-02 Gutin Mikhail Optical coherence tomography with 3d coherence scanning
US7352892B2 (en) 2003-03-20 2008-04-01 Micron Technology, Inc. System and method for shape reconstruction from optical images
US7408176B2 (en) 2003-06-19 2008-08-05 Applied Precision, Llc System and method employing photokinetic techniques in cell biology imaging applications
CA2540275A1 (en) * 2003-09-30 2005-04-14 Chiron Corporation Novel splice variants of human dkkl1
JP4575296B2 (ja) * 2003-10-15 2010-11-04 株式会社コーセー 透過光による対象物体内部の評価方法
US7075647B2 (en) 2004-06-30 2006-07-11 Beckman Coulter, Inc. Back-scatter detection in flow cytometers
US20070258122A1 (en) 2004-10-06 2007-11-08 Bc Cancer Agency Computer-Tomography Microscope and Computer-Tomography Image Reconstruction Methods
NZ555575A (en) * 2004-11-05 2010-11-26 Us Gov Sec Navy Diagnosis and prognosis of infectious disease clinical phenotypes and other physiologic states using host gene expression biomarkers in blood
US7491943B2 (en) 2005-01-13 2009-02-17 Whitehead Institute For Biomedical Research Method and apparatus for UV imaging
US7224540B2 (en) 2005-01-31 2007-05-29 Datalogic Scanning, Inc. Extended depth of field imaging system using chromatic aberration
GB0520436D0 (en) * 2005-10-07 2005-11-16 Photobiotics Ltd Biological materials and uses thereof
JP2007113979A (ja) * 2005-10-19 2007-05-10 Ebara Corp マルチ分光分析装置
US8618470B2 (en) * 2005-11-30 2013-12-31 Board Of Trustees Of Michigan State University Laser based identification of molecular characteristics
WO2007067999A2 (en) 2005-12-09 2007-06-14 Amnis Corporation Extended depth of field imaging for high speed object analysis
FR2895897B1 (fr) * 2006-01-12 2008-10-17 Commissariat Energie Atomique Procede et dispositif de reconstruction d'image de tomographie optique de fluorescence par double mesure
US7569789B2 (en) 2006-03-16 2009-08-04 Visiongate, Inc. Cantilevered coaxial flow injector apparatus and method for sorting particles
JP2008026643A (ja) * 2006-07-21 2008-02-07 Olympus Corp レーザ走査型顕微鏡

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7344225B2 (ja) 2018-10-26 2023-09-13 ケーエルエー コーポレイション 結像系設計における微分干渉コントラストの走査

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