JP2011512120A5 - - Google Patents
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- Publication number
- JP2011512120A5 JP2011512120A5 JP2010533123A JP2010533123A JP2011512120A5 JP 2011512120 A5 JP2011512120 A5 JP 2011512120A5 JP 2010533123 A JP2010533123 A JP 2010533123A JP 2010533123 A JP2010533123 A JP 2010533123A JP 2011512120 A5 JP2011512120 A5 JP 2011512120A5
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- JP
- Japan
- Prior art keywords
- seq
- antigen
- binding fragment
- antibody
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000427 antigen Substances 0.000 claims 23
- 102000036639 antigens Human genes 0.000 claims 23
- 108091007433 antigens Proteins 0.000 claims 23
- 239000012634 fragment Substances 0.000 claims 23
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 108020004414 DNA Proteins 0.000 claims 3
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 208000006673 asthma Diseases 0.000 claims 3
- 239000013598 vector Substances 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 2
- 208000035475 disorder Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 claims 1
- 201000003883 Cystic fibrosis Diseases 0.000 claims 1
- 101000746373 Homo sapiens Granulocyte-macrophage colony-stimulating factor Proteins 0.000 claims 1
- 208000029523 Interstitial Lung disease Diseases 0.000 claims 1
- 208000012659 Joint disease Diseases 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 208000024716 acute asthma Diseases 0.000 claims 1
- 206010003246 arthritis Diseases 0.000 claims 1
- 238000001516 cell proliferation assay Methods 0.000 claims 1
- 208000029771 childhood onset asthma Diseases 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 230000014509 gene expression Effects 0.000 claims 1
- 102000046157 human CSF2 Human genes 0.000 claims 1
- 208000030603 inherited susceptibility to asthma Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 208000025113 myeloid leukemia Diseases 0.000 claims 1
- 230000002018 overexpression Effects 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 206010039083 rhinitis Diseases 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010533123A JP5476310B2 (ja) | 2008-02-14 | 2008-11-12 | ｈＧＭ−ＣＳＦに結合するモノクローナル抗体および前記抗体を含む医薬組成物 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JPPCT/JP2008/052471 | 2008-02-14 | ||
| JP2008052471 | 2008-02-14 | ||
| JP2010533123A JP5476310B2 (ja) | 2008-02-14 | 2008-11-12 | ｈＧＭ−ＣＳＦに結合するモノクローナル抗体および前記抗体を含む医薬組成物 |
| PCT/US2008/012680 WO2009064399A1 (en) | 2007-11-13 | 2008-11-12 | Monoclonal antibodies that bind to hgm-csf and medical compositions comprising same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012006807A Division JP2012105657A (ja) | 2008-02-14 | 2012-01-17 | ｈＧＭ−ＣＳＦに結合するモノクローナル抗体および前記抗体を含む医薬組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011512120A JP2011512120A (ja) | 2011-04-21 |
| JP2011512120A5 true JP2011512120A5 (enExample) | 2012-01-12 |
| JP5476310B2 JP5476310B2 (ja) | 2014-04-23 |
Family
ID=44080162
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010533123A Active JP5476310B2 (ja) | 2008-02-14 | 2008-11-12 | ｈＧＭ−ＣＳＦに結合するモノクローナル抗体および前記抗体を含む医薬組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP5476310B2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2914289B1 (en) * | 2012-10-31 | 2019-05-22 | Takeda GmbH | Lyophilized formulation comprising gm-csf neutralizing compound |
| JP6962514B2 (ja) * | 2016-03-29 | 2021-11-05 | ノーベルファーマ株式会社 | 酵母由来組換えヒトｇｍ−ｃｓｆに特異的に結合するモノクローナル抗体 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4736037B2 (ja) * | 2005-10-26 | 2011-07-27 | 株式会社イーベック | ヒトｇｍ−ｃｓｆに結合するヒトのモノクローナル抗体並びにその抗原結合部分 |
| CN101501070B (zh) * | 2006-02-08 | 2013-12-25 | 诺福泰克公司 | 抗原性gm-csf肽和针对gm-csf的抗体 |
-
2008
- 2008-11-12 JP JP2010533123A patent/JP5476310B2/ja active Active
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