JP2011511776A - RNA干渉のためのカチオン性siRNA、合成及び使用 - Google Patents
RNA干渉のためのカチオン性siRNA、合成及び使用 Download PDFInfo
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| FR0800492A FR2926818B1 (fr) | 2008-01-30 | 2008-01-30 | siRNA CATIONIQUES, SYNTHESE ET UTILISATION POUR L'ARN INTERFERENCE |
| PCT/IB2009/050379 WO2009095887A1 (fr) | 2008-01-30 | 2009-01-30 | siRNA CATIONIQUES, SYNTHÈSE ET UTILISATION POUR L'ARN INTERFÉRENCE |
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| JP2011511776A true JP2011511776A (ja) | 2011-04-14 |
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| AU2006325054B2 (en) * | 2005-12-15 | 2013-05-02 | Centre National De La Recherche Scientifique (Cnrs) | Cationic oligonucleotides, automated methods for preparing same and their uses |
| WO2015015498A1 (en) * | 2013-07-31 | 2015-02-05 | Qbi Enterprises Ltd. | Methods of use of sphingolipid polyalkylamine oligonucleotide compounds |
| AU2016226418B2 (en) | 2015-03-02 | 2022-05-26 | Synthetic Genomics, Inc. | Regulatory elements from labyrinthulomycetes microorganisms |
| US10633454B2 (en) | 2016-11-01 | 2020-04-28 | Conagen Inc. | Expression of modified glycoproteins and glycopeptides |
| EP3535385A4 (en) * | 2016-11-01 | 2020-06-17 | Conagen Inc. | EXPRESSION OF MODIFIED GLYCOPROTEINS AND GLYCOPEPTIDES |
| CN106498072B (zh) * | 2016-11-24 | 2019-09-10 | 青岛千卓分子生物科技有限公司 | 一种液态产品中外源dna内标物的保护方法及其应用 |
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| WO2006052854A2 (en) * | 2004-11-04 | 2006-05-18 | Raul Andino | Syntheses of polyamine conjugates of small interfering rnas (si-rnas) and conjugates formed thereby |
| WO2007069092A2 (en) * | 2005-12-15 | 2007-06-21 | Centre National De La Recherche Scientifique (Cnrs) | Cationic oligonucleotides, automated methods for preparing same and their uses |
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| US6071890A (en) | 1994-12-09 | 2000-06-06 | Genzyme Corporation | Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy |
| EP1013770A1 (en) | 1998-12-23 | 2000-06-28 | Université Louis Pasteur de Strasbourg | Non-viral transfection vector |
| DE10207177A1 (de) | 2002-02-19 | 2003-09-04 | Novosom Ag | Fakultativ kationische Lipide |
| US20040019008A1 (en) | 2002-05-28 | 2004-01-29 | Lewis David L. | Compositions and processes using siRNA, amphipathic compounds and polycations |
| JP2004137143A (ja) | 2002-08-21 | 2004-05-13 | Fuji Photo Film Co Ltd | 有機変性層状珪酸塩及びその組成物 |
| EP1585756B1 (en) * | 2002-11-26 | 2010-04-21 | University of Massachusetts | Delivery of sirnas |
| EP1638919B1 (en) * | 2003-06-18 | 2012-09-26 | Biolab Ltd. | Sphingolipids polyalkylamines conjugates |
| WO2005060697A2 (en) * | 2003-12-19 | 2005-07-07 | Chiron Corporation | Cell transfecting formulations of small interfering rna, related compositions and methods of making and use |
| US20060073505A1 (en) * | 2004-09-21 | 2006-04-06 | Isis Pharmaceuticals, Inc. | Oligomeric compounds effecting drosha-mediated cleavage |
| CA2587962A1 (en) * | 2004-11-17 | 2006-06-08 | University Of Maryland, Baltimore | Highly branched hk peptides as effective carriers of sirna |
| EP1844772A1 (en) | 2006-04-06 | 2007-10-17 | Polyplus-Transfection SA | Compositions for transfection of oligonucleotides active for gene silencing and their biological and therapeutical applications |
| EP2992875A1 (en) * | 2006-04-20 | 2016-03-09 | Silence Therapeutics GmbH | Lipoplex formulations for specific delivery to vascular endothelium |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006052854A2 (en) * | 2004-11-04 | 2006-05-18 | Raul Andino | Syntheses of polyamine conjugates of small interfering rnas (si-rnas) and conjugates formed thereby |
| WO2007069092A2 (en) * | 2005-12-15 | 2007-06-21 | Centre National De La Recherche Scientifique (Cnrs) | Cationic oligonucleotides, automated methods for preparing same and their uses |
Non-Patent Citations (2)
| Title |
|---|
| JPN6013030804; Bioconjugate Chemistry Vol.18, No.5, 2007, pp.1450-1459 * |
| JPN6013030806; FEBS Letters Vol.558, No.1-3, 2004, pp.63-68 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2009208646A1 (en) | 2009-08-06 |
| US10927371B2 (en) | 2021-02-23 |
| CA2713075A1 (fr) | 2009-08-06 |
| EP2250267B1 (fr) | 2016-09-14 |
| CN101960009A (zh) | 2011-01-26 |
| EP2250267A1 (fr) | 2010-11-17 |
| FR2926818B1 (fr) | 2012-04-06 |
| KR20100120293A (ko) | 2010-11-15 |
| WO2009095887A1 (fr) | 2009-08-06 |
| IL207290A0 (en) | 2010-12-30 |
| FR2926818A1 (fr) | 2009-07-31 |
| NZ587117A (en) | 2012-09-28 |
| BRPI0907494A2 (pt) | 2019-09-24 |
| RU2010136047A (ru) | 2012-03-10 |
| US20110118331A1 (en) | 2011-05-19 |
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