IL207290A0 - CATIONIC siRNAs, SYNTHESIS AND USE FOR INTERFERING RNA - Google Patents

CATIONIC siRNAs, SYNTHESIS AND USE FOR INTERFERING RNA

Info

Publication number
IL207290A0
IL207290A0 IL207290A IL20729010A IL207290A0 IL 207290 A0 IL207290 A0 IL 207290A0 IL 207290 A IL207290 A IL 207290A IL 20729010 A IL20729010 A IL 20729010A IL 207290 A0 IL207290 A0 IL 207290A0
Authority
IL
Israel
Prior art keywords
synthesis
interfering rna
cationic sirnas
sirnas
cationic
Prior art date
Application number
IL207290A
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Publication of IL207290A0 publication Critical patent/IL207290A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/111—General methods applicable to biologically active non-coding nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering N.A.
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/35—Nature of the modification
    • C12N2310/351—Conjugate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/30—Special therapeutic applications
    • C12N2320/32—Special delivery means, e.g. tissue-specific

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
IL207290A 2008-01-30 2010-07-29 CATIONIC siRNAs, SYNTHESIS AND USE FOR INTERFERING RNA IL207290A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0800492A FR2926818B1 (en) 2008-01-30 2008-01-30 CATIONIC siRNA, SYNTHESIS AND USE FOR RNA INTERFERENCE
PCT/IB2009/050379 WO2009095887A1 (en) 2008-01-30 2009-01-30 Cationic sirnas, synthesis and use for interfering rna

Publications (1)

Publication Number Publication Date
IL207290A0 true IL207290A0 (en) 2010-12-30

Family

ID=39683957

Family Applications (1)

Application Number Title Priority Date Filing Date
IL207290A IL207290A0 (en) 2008-01-30 2010-07-29 CATIONIC siRNAs, SYNTHESIS AND USE FOR INTERFERING RNA

Country Status (13)

Country Link
US (1) US10927371B2 (en)
EP (1) EP2250267B1 (en)
JP (1) JP2011511776A (en)
KR (1) KR20100120293A (en)
CN (1) CN101960009A (en)
AU (1) AU2009208646A1 (en)
BR (1) BRPI0907494A2 (en)
CA (1) CA2713075A1 (en)
FR (1) FR2926818B1 (en)
IL (1) IL207290A0 (en)
NZ (1) NZ587117A (en)
RU (1) RU2010136047A (en)
WO (1) WO2009095887A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ569138A (en) * 2005-12-15 2012-06-29 Centre Nat Rech Scient Cationic oligonucleotides automated methods for preparing same and their uses
WO2015015498A1 (en) * 2013-07-31 2015-02-05 Qbi Enterprises Ltd. Methods of use of sphingolipid polyalkylamine oligonucleotide compounds
CA2977271A1 (en) 2015-03-02 2016-09-09 Synthetic Genomics, Inc. Regulatory elements from labyrinthulomycetes microorganisms
EP3535385A4 (en) * 2016-11-01 2020-06-17 Conagen Inc. Expression of modified glycoproteins and glycopeptides
US10633454B2 (en) 2016-11-01 2020-04-28 Conagen Inc. Expression of modified glycoproteins and glycopeptides
CN106498072B (en) * 2016-11-24 2019-09-10 青岛千卓分子生物科技有限公司 The guard method and its application of exogenous DNA internal standard compound in a kind of liquid form product

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071890A (en) 1994-12-09 2000-06-06 Genzyme Corporation Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy
EP1013770A1 (en) 1998-12-23 2000-06-28 Université Louis Pasteur de Strasbourg Non-viral transfection vector
DE10207177A1 (en) 2002-02-19 2003-09-04 Novosom Ag Optionally cationic lipids
US20040019008A1 (en) 2002-05-28 2004-01-29 Lewis David L. Compositions and processes using siRNA, amphipathic compounds and polycations
JP2004137143A (en) 2002-08-21 2004-05-13 Fuji Photo Film Co Ltd Organic-modified layered silicate and composition of the same
ES2343318T3 (en) * 2002-11-26 2010-07-28 University Of Massachusetts ARNSIS ADMINISTRATION.
AU2004247505B2 (en) * 2003-06-18 2010-01-21 Biolab Ltd. Sphingolipids' polyalkylamines conjugates
AU2004305111B2 (en) * 2003-12-19 2011-04-28 Novartis Vaccines And Diagnostics, Inc. Cell transfecting formulations of small interfering RNA, related compositions and methods of making and use
US20060073505A1 (en) * 2004-09-21 2006-04-06 Isis Pharmaceuticals, Inc. Oligomeric compounds effecting drosha-mediated cleavage
CA2581869A1 (en) * 2004-11-04 2006-05-18 Raul Andino Syntheses of polyamine conjugates of small interfering rnas (si-rnas) and conjugates formed thereby
EP1812016A4 (en) * 2004-11-17 2010-07-14 Univ Maryland HIGHLY BRANCHED HK PEPTIDES AS EFFECTIVE CARRIERS OF siRNA
NZ569138A (en) 2005-12-15 2012-06-29 Centre Nat Rech Scient Cationic oligonucleotides automated methods for preparing same and their uses
EP1844772A1 (en) 2006-04-06 2007-10-17 Polyplus-Transfection SA Compositions for transfection of oligonucleotides active for gene silencing and their biological and therapeutical applications
AU2007241370A1 (en) * 2006-04-20 2007-11-01 Silence Therapeutics Ag. Lipoplex formulations for specific delivery to vascular endothelium

Also Published As

Publication number Publication date
EP2250267B1 (en) 2016-09-14
US20110118331A1 (en) 2011-05-19
AU2009208646A1 (en) 2009-08-06
JP2011511776A (en) 2011-04-14
CN101960009A (en) 2011-01-26
NZ587117A (en) 2012-09-28
RU2010136047A (en) 2012-03-10
BRPI0907494A2 (en) 2019-09-24
US10927371B2 (en) 2021-02-23
WO2009095887A1 (en) 2009-08-06
EP2250267A1 (en) 2010-11-17
FR2926818A1 (en) 2009-07-31
FR2926818B1 (en) 2012-04-06
KR20100120293A (en) 2010-11-15
CA2713075A1 (en) 2009-08-06

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