IL207290A0 - CATIONIC siRNAs, SYNTHESIS AND USE FOR INTERFERING RNA - Google Patents
CATIONIC siRNAs, SYNTHESIS AND USE FOR INTERFERING RNAInfo
- Publication number
- IL207290A0 IL207290A0 IL207290A IL20729010A IL207290A0 IL 207290 A0 IL207290 A0 IL 207290A0 IL 207290 A IL207290 A IL 207290A IL 20729010 A IL20729010 A IL 20729010A IL 207290 A0 IL207290 A0 IL 207290A0
- Authority
- IL
- Israel
- Prior art keywords
- synthesis
- interfering rna
- cationic sirnas
- sirnas
- cationic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/351—Conjugate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/32—Special delivery means, e.g. tissue-specific
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0800492A FR2926818B1 (en) | 2008-01-30 | 2008-01-30 | CATIONIC siRNA, SYNTHESIS AND USE FOR RNA INTERFERENCE |
PCT/IB2009/050379 WO2009095887A1 (en) | 2008-01-30 | 2009-01-30 | Cationic sirnas, synthesis and use for interfering rna |
Publications (1)
Publication Number | Publication Date |
---|---|
IL207290A0 true IL207290A0 (en) | 2010-12-30 |
Family
ID=39683957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL207290A IL207290A0 (en) | 2008-01-30 | 2010-07-29 | CATIONIC siRNAs, SYNTHESIS AND USE FOR INTERFERING RNA |
Country Status (13)
Country | Link |
---|---|
US (1) | US10927371B2 (en) |
EP (1) | EP2250267B1 (en) |
JP (1) | JP2011511776A (en) |
KR (1) | KR20100120293A (en) |
CN (1) | CN101960009A (en) |
AU (1) | AU2009208646A1 (en) |
BR (1) | BRPI0907494A2 (en) |
CA (1) | CA2713075A1 (en) |
FR (1) | FR2926818B1 (en) |
IL (1) | IL207290A0 (en) |
NZ (1) | NZ587117A (en) |
RU (1) | RU2010136047A (en) |
WO (1) | WO2009095887A1 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ569138A (en) * | 2005-12-15 | 2012-06-29 | Centre Nat Rech Scient | Cationic oligonucleotides automated methods for preparing same and their uses |
WO2015015498A1 (en) * | 2013-07-31 | 2015-02-05 | Qbi Enterprises Ltd. | Methods of use of sphingolipid polyalkylamine oligonucleotide compounds |
CA2977271A1 (en) | 2015-03-02 | 2016-09-09 | Synthetic Genomics, Inc. | Regulatory elements from labyrinthulomycetes microorganisms |
EP3535385A4 (en) * | 2016-11-01 | 2020-06-17 | Conagen Inc. | Expression of modified glycoproteins and glycopeptides |
US10633454B2 (en) | 2016-11-01 | 2020-04-28 | Conagen Inc. | Expression of modified glycoproteins and glycopeptides |
CN106498072B (en) * | 2016-11-24 | 2019-09-10 | 青岛千卓分子生物科技有限公司 | The guard method and its application of exogenous DNA internal standard compound in a kind of liquid form product |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6071890A (en) | 1994-12-09 | 2000-06-06 | Genzyme Corporation | Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy |
EP1013770A1 (en) | 1998-12-23 | 2000-06-28 | Université Louis Pasteur de Strasbourg | Non-viral transfection vector |
DE10207177A1 (en) | 2002-02-19 | 2003-09-04 | Novosom Ag | Optionally cationic lipids |
US20040019008A1 (en) | 2002-05-28 | 2004-01-29 | Lewis David L. | Compositions and processes using siRNA, amphipathic compounds and polycations |
JP2004137143A (en) | 2002-08-21 | 2004-05-13 | Fuji Photo Film Co Ltd | Organic-modified layered silicate and composition of the same |
ES2343318T3 (en) * | 2002-11-26 | 2010-07-28 | University Of Massachusetts | ARNSIS ADMINISTRATION. |
AU2004247505B2 (en) * | 2003-06-18 | 2010-01-21 | Biolab Ltd. | Sphingolipids' polyalkylamines conjugates |
AU2004305111B2 (en) * | 2003-12-19 | 2011-04-28 | Novartis Vaccines And Diagnostics, Inc. | Cell transfecting formulations of small interfering RNA, related compositions and methods of making and use |
US20060073505A1 (en) * | 2004-09-21 | 2006-04-06 | Isis Pharmaceuticals, Inc. | Oligomeric compounds effecting drosha-mediated cleavage |
CA2581869A1 (en) * | 2004-11-04 | 2006-05-18 | Raul Andino | Syntheses of polyamine conjugates of small interfering rnas (si-rnas) and conjugates formed thereby |
EP1812016A4 (en) * | 2004-11-17 | 2010-07-14 | Univ Maryland | HIGHLY BRANCHED HK PEPTIDES AS EFFECTIVE CARRIERS OF siRNA |
NZ569138A (en) | 2005-12-15 | 2012-06-29 | Centre Nat Rech Scient | Cationic oligonucleotides automated methods for preparing same and their uses |
EP1844772A1 (en) | 2006-04-06 | 2007-10-17 | Polyplus-Transfection SA | Compositions for transfection of oligonucleotides active for gene silencing and their biological and therapeutical applications |
AU2007241370A1 (en) * | 2006-04-20 | 2007-11-01 | Silence Therapeutics Ag. | Lipoplex formulations for specific delivery to vascular endothelium |
-
2008
- 2008-01-30 FR FR0800492A patent/FR2926818B1/en active Active
-
2009
- 2009-01-30 NZ NZ587117A patent/NZ587117A/en not_active IP Right Cessation
- 2009-01-30 JP JP2010544836A patent/JP2011511776A/en active Pending
- 2009-01-30 EP EP09707000.7A patent/EP2250267B1/en active Active
- 2009-01-30 US US12/735,595 patent/US10927371B2/en active Active
- 2009-01-30 AU AU2009208646A patent/AU2009208646A1/en not_active Abandoned
- 2009-01-30 CN CN200980107841XA patent/CN101960009A/en active Pending
- 2009-01-30 BR BRPI0907494A patent/BRPI0907494A2/en not_active IP Right Cessation
- 2009-01-30 CA CA2713075A patent/CA2713075A1/en not_active Abandoned
- 2009-01-30 WO PCT/IB2009/050379 patent/WO2009095887A1/en active Application Filing
- 2009-01-30 RU RU2010136047/10A patent/RU2010136047A/en not_active Application Discontinuation
- 2009-01-30 KR KR1020107019289A patent/KR20100120293A/en not_active Application Discontinuation
-
2010
- 2010-07-29 IL IL207290A patent/IL207290A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP2250267B1 (en) | 2016-09-14 |
US20110118331A1 (en) | 2011-05-19 |
AU2009208646A1 (en) | 2009-08-06 |
JP2011511776A (en) | 2011-04-14 |
CN101960009A (en) | 2011-01-26 |
NZ587117A (en) | 2012-09-28 |
RU2010136047A (en) | 2012-03-10 |
BRPI0907494A2 (en) | 2019-09-24 |
US10927371B2 (en) | 2021-02-23 |
WO2009095887A1 (en) | 2009-08-06 |
EP2250267A1 (en) | 2010-11-17 |
FR2926818A1 (en) | 2009-07-31 |
FR2926818B1 (en) | 2012-04-06 |
KR20100120293A (en) | 2010-11-15 |
CA2713075A1 (en) | 2009-08-06 |
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