JP2011508789A5 - - Google Patents

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Publication number
JP2011508789A5
JP2011508789A5 JP2010542438A JP2010542438A JP2011508789A5 JP 2011508789 A5 JP2011508789 A5 JP 2011508789A5 JP 2010542438 A JP2010542438 A JP 2010542438A JP 2010542438 A JP2010542438 A JP 2010542438A JP 2011508789 A5 JP2011508789 A5 JP 2011508789A5
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JP
Japan
Prior art keywords
drug depot
adrenergic agonist
period
lactide
over
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010542438A
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English (en)
Japanese (ja)
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JP2011508789A (ja
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Priority claimed from US12/420,192 external-priority patent/US9072727B2/en
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Publication of JP2011508789A publication Critical patent/JP2011508789A/ja
Publication of JP2011508789A5 publication Critical patent/JP2011508789A5/ja
Pending legal-status Critical Current

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JP2010542438A 2008-04-18 2009-04-17 変性円板疾患の治療のためのαアドレナリン作動性受容体アゴニスト Pending JP2011508789A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4620108P 2008-04-18 2008-04-18
US12/420,192 US9072727B2 (en) 2008-04-18 2009-04-08 Alpha adrenergic receptor agonists for treatment of degenerative disc disease
PCT/US2009/040898 WO2009129433A2 (en) 2008-04-18 2009-04-17 Alpha adrenergic receptor agonists for treatment of degenerative disc disease

Publications (2)

Publication Number Publication Date
JP2011508789A JP2011508789A (ja) 2011-03-17
JP2011508789A5 true JP2011508789A5 (enExample) 2011-05-12

Family

ID=41199749

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010542438A Pending JP2011508789A (ja) 2008-04-18 2009-04-17 変性円板疾患の治療のためのαアドレナリン作動性受容体アゴニスト

Country Status (6)

Country Link
US (2) US9072727B2 (enExample)
EP (1) EP2276469B1 (enExample)
JP (1) JP2011508789A (enExample)
CN (1) CN101842086A (enExample)
BR (1) BRPI0904962A2 (enExample)
WO (1) WO2009129433A2 (enExample)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080161929A1 (en) 2006-12-29 2008-07-03 Mccormack Bruce Cervical distraction device
US20090110637A1 (en) * 2007-10-26 2009-04-30 Warsaw Orthopedic, Inc. LMP and Regulation of Tissue Growth
US9005288B2 (en) 2008-01-09 2015-04-14 Providence Medical Techonlogy, Inc. Methods and apparatus for accessing and treating the facet joint
USRE48948E1 (en) 2008-04-18 2022-03-01 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable polymer
US8629172B2 (en) * 2008-04-18 2014-01-14 Warsaw Orthopedic, Inc. Methods and compositions for treating post-operative pain comprising clonidine
US11224521B2 (en) 2008-06-06 2022-01-18 Providence Medical Technology, Inc. Cervical distraction/implant delivery device
WO2010030994A2 (en) 2008-06-06 2010-03-18 Providence Medical Technology, Inc. Cervical distraction/implant delivery device
CA2725811A1 (en) 2008-06-06 2009-12-10 Providence Medical Technology, Inc. Facet joint implants and delivery tools
US9333086B2 (en) 2008-06-06 2016-05-10 Providence Medical Technology, Inc. Spinal facet cage implant
US9381049B2 (en) 2008-06-06 2016-07-05 Providence Medical Technology, Inc. Composite spinal facet implant with textured surfaces
US8361152B2 (en) 2008-06-06 2013-01-29 Providence Medical Technology, Inc. Facet joint implants and delivery tools
US8267966B2 (en) 2008-06-06 2012-09-18 Providence Medical Technology, Inc. Facet joint implants and delivery tools
US20100239632A1 (en) 2009-03-23 2010-09-23 Warsaw Orthopedic, Inc. Drug depots for treatment of pain and inflammation in sinus and nasal cavities or cardiac tissue
US20120148678A1 (en) * 2010-12-08 2012-06-14 Advanced Technologies And Regenerative Medicine, Llc. Sustained release of poorly water soluble active compounds
USD745156S1 (en) 2012-10-23 2015-12-08 Providence Medical Technology, Inc. Spinal implant
USD732667S1 (en) 2012-10-23 2015-06-23 Providence Medical Technology, Inc. Cage spinal implant
CN107072697A (zh) 2014-05-27 2017-08-18 普罗维登斯医疗技术公司 侧块固定植入件
JP2017520357A (ja) 2014-05-28 2017-07-27 プロビデンス メディカル テクノロジー インコーポレイテッド 外側塊固定システム
GB201505527D0 (en) 2015-03-31 2015-05-13 Jmedtech Pte Ltd Composition
US10449055B2 (en) 2015-04-23 2019-10-22 Disc Fix L.L.C. Systems and methods for treatment of intervertebral disc derangements
CN108289689A (zh) 2015-10-13 2018-07-17 普罗维登斯医疗技术公司 脊柱关节植入物输送装置和系统
USD841165S1 (en) 2015-10-13 2019-02-19 Providence Medical Technology, Inc. Cervical cage
JP2019519334A (ja) 2016-06-28 2019-07-11 プロビデンス メディカル テクノロジー インコーポレイテッド 脊椎インプラント及び脊椎インプラントの使用方法
USD887552S1 (en) 2016-07-01 2020-06-16 Providence Medical Technology, Inc. Cervical cage
EP3490542A4 (en) * 2016-07-26 2020-07-08 Flagship Pioneering Innovations V, Inc. NEUROMODULATION COMPOSITIONS AND RELATED THERAPEUTIC METHODS FOR THE TREATMENT OF CANCER BY MODULATION OF AN ANTI-CANCER RESPONSE
JP2020521536A (ja) 2017-05-19 2020-07-27 プロビデンス メディカル テクノロジー インコーポレイテッド 脊椎固定アクセス及び送達システム
EP3691618A1 (en) 2017-10-06 2020-08-12 Foundry Therapeutics, Inc. Implantable depots for the controlled release of therapeutic agents
WO2019136263A1 (en) 2018-01-04 2019-07-11 Providence Medical Technology, Inc. Facet screw and delivery device
CN116650732A (zh) 2018-01-08 2023-08-29 铸造疗法股份有限公司 经由治疗剂的控制递送用于治疗腔内癌症的装置、系统和方法
US11911504B2 (en) 2018-02-02 2024-02-27 Galen Therapeutics Llc Apparatus and method for protecting neurons and reducing inflammation and scarring
US12458589B2 (en) 2018-05-12 2025-11-04 Foundry Therapeutics, Inc. Implantable polymer depots for the controlled release of therapeutic agents
EP3843710A1 (en) 2018-08-28 2021-07-07 Foundry Therapeutics, Inc. Polymer implants
US12144513B2 (en) 2018-09-21 2024-11-19 Providence Medical Technology, Inc. Vertebral joint access and decortication devices and methods of using
USD933230S1 (en) 2019-04-15 2021-10-12 Providence Medical Technology, Inc. Cervical cage
CN113795246B (zh) * 2019-05-06 2024-10-11 福多兹制药公司 用于治疗关节疼痛和炎症的可注射缓释制剂
USD911525S1 (en) 2019-06-21 2021-02-23 Providence Medical Technology, Inc. Spinal cage
USD945621S1 (en) 2020-02-27 2022-03-08 Providence Medical Technology, Inc. Spinal cage
US12383246B2 (en) 2020-10-12 2025-08-12 Abbott Cardiovascular Systems, Inc. Vessel closure device with improved safety and tract hemostasis
US20230404979A1 (en) * 2020-10-26 2023-12-21 Rush University Medical Center Alpha-2 adrenergic receptor agonists to reduce mortality and improve outcomes in viral respiratory syndromes
USD1098431S1 (en) 2023-02-27 2025-10-14 Providence Medical Technology, Inc. Spinal cage
USD1098433S1 (en) 2023-12-28 2025-10-14 Providence Medical Technology, Inc. Spinal cage
WO2025231265A1 (en) * 2024-05-01 2025-11-06 Alpherabio Llc Combination with alpha-2 adrenergic receptor agonist
CN121154628A (zh) * 2025-11-21 2025-12-19 武汉大学人民医院(湖北省人民医院) 酚妥拉明在制备治疗椎间盘退行性病变的药物中的应用

Family Cites Families (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3020660A (en) 1959-11-30 1962-02-13 Scherotto John Collapsible imitation tree
US3202660A (en) 1961-10-09 1965-08-24 Boehringer Sohn Ingelheim Process for the preparation of 3-arylamino-1, 3-diazacycloalkenes
US3883140A (en) 1974-02-01 1975-05-13 Joseph T Becker Target and sliding projectile
US4231938A (en) 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
US4450171A (en) 1980-08-05 1984-05-22 Merck & Co., Inc. Antihypercholesterolemic compounds
US4624255A (en) 1982-02-18 1986-11-25 Schenck Robert R Apparatus for anastomosing living vessels
US4448784A (en) 1982-04-12 1984-05-15 Hoechst-Roussel Pharmaceuticals, Inc. 1-(Aminoalkylphenyl and aminoalkylbenzyl)-indoles and indolines and analgesic method of use thereof
US4742054A (en) 1982-11-23 1988-05-03 Naftchi Nosrat E Treatment of mammals suffering from damage to the central nervous system
US4765974A (en) 1985-12-24 1988-08-23 Nitto Electric Industrial Co., Ltd. Preparation for percutaneous administration
US4863457A (en) 1986-11-24 1989-09-05 Lee David A Drug delivery device
US5175052A (en) 1988-05-11 1992-12-29 Nitto Denko Corporation Adhesive tape preparation of clonidine
US5447947A (en) 1990-02-26 1995-09-05 Arc 1 Compositions and methods of treatment of sympathetically maintained pain
US5212176A (en) 1990-06-29 1993-05-18 Abbott Laboratories R(+)-terazosin
EP0573581A4 (en) * 1991-02-26 1994-06-29 Arc 1 Inc Compositions and methods of treatment of sympathetically maintained pain
US5868789A (en) 1997-02-03 1999-02-09 Huebner; Randall J. Removable suture anchor apparatus
US5522844A (en) 1993-06-22 1996-06-04 Johnson; Lanny L. Suture anchor, suture anchor installation device and method for attaching a suture to a bone
US5484607A (en) 1993-10-13 1996-01-16 Horacek; H. Joseph Extended release clonidine formulation
US5635204A (en) 1994-03-04 1997-06-03 Montefiore Medical Center Method for transdermal induction of anesthesia, analgesia or sedation
US6447796B1 (en) * 1994-05-16 2002-09-10 The United States Of America As Represented By The Secretary Of The Army Sustained release hydrophobic bioactive PLGA microspheres
DE69603577T2 (de) * 1995-02-10 1999-11-25 Medtronic, Inc. Verfahren und vorrichtung zur verabreichung von analgetika
US5626838A (en) 1995-03-13 1997-05-06 The Procter & Gamble Company Use of ketorolac for treatment of squamous cell carcinomas of the oral cavity or oropharynx
EP0738510A3 (fr) 1995-04-20 2005-12-21 L'oreal Utilisation d'un inhibiteur d'HMG-coenzyme A-reductase pour lutter contre le vieillissement de la peau et pour traiter l'acné. Composition comprenant au moins un inhibiteur HMG-coenzyme A reductase et au moins un actif possédant des propriétes desquamantes
US7069634B1 (en) 1995-04-28 2006-07-04 Medtronic, Inc. Method for manufacturing a catheter
US5752930A (en) 1995-04-28 1998-05-19 Medtronic, Inc. Implantable techniques for infusing equal volumes of agents to spaced sites
US5942241A (en) 1995-06-09 1999-08-24 Euro-Celtique, S.A. Formulations and methods for providing prolonged local anesthesia
US5759583A (en) 1995-08-30 1998-06-02 Syntex (U.S.A.) Inc. Sustained release poly (lactic/glycolic) matrices
DE19542281C2 (de) 1995-11-14 1997-12-04 Boehringer Ingelheim Kg Verwendung von Epinastin für die Behandlung der Migräne
US5677321A (en) 1996-02-29 1997-10-14 Synaptic Pharmaceutical Corporation 5- and 6-(2-imidazolin-2-ylamino) and -(2-thiazolin-2-ylamino)-benzothiazoles as alpha-2 adrenergic ligands
PL187926B1 (pl) 1996-03-25 2004-11-30 Lilly Co Eli Kompozycja farmaceutyczna do leczenia bólu
US7357798B2 (en) * 1996-07-16 2008-04-15 Arthrocare Corporation Systems and methods for electrosurgical prevention of disc herniations
ATE318580T1 (de) 1996-12-20 2006-03-15 Alza Corp Gelzusammensetzungen und verfahren
US5801188A (en) 1997-01-08 1998-09-01 Medtronic Inc. Clonidine therapy enhancement
US6294170B1 (en) 1997-08-08 2001-09-25 Amgen Inc. Composition and method for treating inflammatory diseases
US6495583B1 (en) 1997-03-25 2002-12-17 Synaptic Pharmaceutical Corporation Benzimidazole derivatives
AU7389098A (en) 1997-05-16 1998-12-08 Brigham And Women's Hospital Local anesthetic formulations
IL129951A0 (en) 1997-07-02 2000-02-29 Euro Celtique Sa Prolonged anesthesia in joints and body spaces
US5942530A (en) 1997-08-28 1999-08-24 Eli Lilly And Company Method for treating pain
DE69833000T2 (de) * 1997-09-26 2006-09-07 Noven Pharmaceuticals, Inc., Miami Bio-klebemittelzusammensetzungen
TW577758B (en) 1997-10-27 2004-03-01 Ssp Co Ltd Intra-articular preparation for the treatment of arthropathy
US6069129A (en) 1998-03-13 2000-05-30 Mrs, Llc Elastin derived composition and method of using same
EP1077653B1 (en) 1998-05-12 2004-03-31 Boston Scientific Limited Manual bone anchor placement devices
US6179862B1 (en) 1998-08-14 2001-01-30 Incept Llc Methods and apparatus for in situ formation of hydrogels
US6632457B1 (en) 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US6927044B2 (en) 1998-09-25 2005-08-09 Regeneron Pharmaceuticals, Inc. IL-1 receptor based cytokine traps
US6143314A (en) 1998-10-28 2000-11-07 Atrix Laboratories, Inc. Controlled release liquid delivery compositions with low initial drug burst
US6565874B1 (en) 1998-10-28 2003-05-20 Atrix Laboratories Polymeric delivery formulations of leuprolide with improved efficacy
US6436099B1 (en) 1999-04-23 2002-08-20 Sdgi Holdings, Inc. Adjustable spinal tether
US6287588B1 (en) 1999-04-29 2001-09-11 Macromed, Inc. Agent delivering system comprised of microparticle and biodegradable gel with an improved releasing profile and methods of use thereof
US7220281B2 (en) 1999-08-18 2007-05-22 Intrinsic Therapeutics, Inc. Implant for reinforcing and annulus fibrosis
US7951201B2 (en) 1999-10-20 2011-05-31 Anulex Technologies, Inc. Method and apparatus for the treatment of the intervertebral disc annulus
US6147102A (en) 1999-10-26 2000-11-14 Curatek Pharmaceuticals Holding, Inc. Clonidine preparations
US6461631B1 (en) 1999-11-16 2002-10-08 Atrix Laboratories, Inc. Biodegradable polymer composition
ES2232370T3 (es) 1999-11-29 2005-06-01 Novosis Ag Sistemas transdermicos para la administracion de clonidina.
DK1244388T3 (da) 1999-12-06 2007-05-14 Warsaw Orthopedic Inc Indretning til behandling af mellemhvirvelskiver
US6899716B2 (en) 2000-02-16 2005-05-31 Trans1, Inc. Method and apparatus for spinal augmentation
US6551290B1 (en) 2000-03-31 2003-04-22 Medtronic, Inc. Catheter for target specific drug delivery
US6589549B2 (en) 2000-04-27 2003-07-08 Macromed, Incorporated Bioactive agent delivering system comprised of microparticles within a biodegradable to improve release profiles
US6417184B1 (en) 2000-09-19 2002-07-09 David M. Ockert Triple drug therapy for the treatment and prevention of acute or chronic pain
WO2002058730A2 (en) 2000-11-01 2002-08-01 Allergan, Inc. Compositions for treatment of ocular neovascularization
DE60137542D1 (de) 2001-01-03 2009-03-12 Bausch & Lomb Wirkstoffabgabevorrichtungen mit verzögerter freisetzung mehrere stoffe enthaltend
US6571125B2 (en) 2001-02-12 2003-05-27 Medtronic, Inc. Drug delivery device
US7229441B2 (en) 2001-02-28 2007-06-12 Warsaw Orthopedic, Inc. Flexible systems for spinal stabilization and fixation
US7235043B2 (en) 2001-03-09 2007-06-26 Boston Scientific Scimed Inc. System for implanting an implant and method thereof
IL142933A0 (en) 2001-05-03 2002-04-21 Dentis Technology Ltd Polymeric dental implant and method for use thereof
WO2002089794A1 (en) 2001-05-07 2002-11-14 Universite Catholique De Louvain Method for treating neuropathic pain and pharmaceutical preparation therefor
CA2446904A1 (en) 2001-05-24 2003-04-03 Alexza Pharmaceuticals, Inc. Delivery of drug esters through an inhalation route
US6602911B2 (en) 2001-11-05 2003-08-05 Cypress Bioscience, Inc. Methods of treating fibromyalgia
MXPA01011542A (es) 2001-11-13 2003-05-22 Alcon Inc Regeneracion del cartilago articular da°ado por la osteoartritis de grado i y ii, mediante la aplicacion intra-articular de una mezcla de hialuronato de sodio y de condroitin sulfato en un vehiculo de gel.
ATE507816T1 (de) * 2001-11-14 2011-05-15 Durect Corp Injizierbare depotzusammensetzungen und deren verwendung
US6974462B2 (en) 2001-12-19 2005-12-13 Boston Scientific Scimed, Inc. Surgical anchor implantation device
US8133501B2 (en) 2002-02-08 2012-03-13 Boston Scientific Scimed, Inc. Implantable or insertable medical devices for controlled drug delivery
US7345065B2 (en) 2002-05-21 2008-03-18 Allergan, Inc. Methods and compositions for alleviating pain
US20040109893A1 (en) 2002-06-25 2004-06-10 Guohua Chen Sustained release dosage forms of anesthetics for pain management
EP1531757B1 (en) 2002-07-19 2016-09-07 Omeros Corporation Biodegradable triblock copolymers, synthesis methods therefor, and hydrogels and biomaterials made there from
US7368126B2 (en) * 2002-11-06 2008-05-06 Guohua Chen Controlled release depot formulations
US7687080B2 (en) 2002-11-25 2010-03-30 Taraxos Inc. Treatment of neuropathy
WO2004060346A2 (en) * 2002-12-30 2004-07-22 Angiotech International Ag Drug delivery from rapid gelling polymer composition
US20040166088A1 (en) 2003-01-15 2004-08-26 Shalaby Shalaby W. Polymeric precursors of non-absorbable, in situ-forming hydrogels and applications thereof
US20040208917A1 (en) 2003-04-16 2004-10-21 Wilfried Fischer Transdermal systems for the release of clonidine
US7141597B2 (en) 2003-09-12 2006-11-28 Allergan, Inc. Nonsedating α-2 agonists
US7144412B2 (en) 2003-06-25 2006-12-05 Wolf Medical Enterprises, Inc. Gold suture and method of use in wound closure
US20050095277A1 (en) 2003-06-25 2005-05-05 Binnur Ozturk Neuropathy cream
US20040265364A1 (en) 2003-06-25 2004-12-30 Binnur Ozturk Neuropathy cream
EP1663311A2 (en) 2003-09-12 2006-06-07 Allergan, Inc. Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions
US20050058696A1 (en) 2003-09-12 2005-03-17 Allergan, Inc. Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions
US20050059744A1 (en) 2003-09-12 2005-03-17 Allergan, Inc. Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions
CA2540895C (en) 2003-10-02 2016-08-02 Elan Pharmaceuticals, Inc. Combinations of ziconotide and opioids for reducing pain
WO2005046746A2 (en) 2003-11-10 2005-05-26 Angiotech International Ag Medical implants and fibrosis-inducing agents
US20050175709A1 (en) 2003-12-11 2005-08-11 Baty Ace M.Iii Therapeutic microparticles
JP2007519756A (ja) 2004-01-30 2007-07-19 アンジオテック インターナショナル アーゲー 拘縮を治療するための組成物および方法
US7361168B2 (en) 2004-04-21 2008-04-22 Acclarent, Inc. Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders
US7410480B2 (en) 2004-04-21 2008-08-12 Acclarent, Inc. Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders
US20050244463A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular vasculopathies
US8529927B2 (en) * 2004-04-30 2013-09-10 Allergan, Inc. Alpha-2 agonist polymeric drug delivery systems
US7589057B2 (en) * 2004-04-30 2009-09-15 Allergan, Inc. Oil-in-water method for making alpha-2 agonist polymeric drug delivery systems
US8147865B2 (en) 2004-04-30 2012-04-03 Allergan, Inc. Steroid-containing sustained release intraocular implants and related methods
US20050245905A1 (en) 2004-04-30 2005-11-03 Schmidt Steven P Local drug-delivery system
WO2006022611A2 (en) 2004-06-26 2006-03-02 Binnur Ozturk Neuropathy cream
US8512730B2 (en) 2004-07-12 2013-08-20 Isto Technologies, Inc. Methods of tissue repair and compositions therefor
US20060074422A1 (en) 2004-09-27 2006-04-06 Story Brooks J Suture anchor and void filler combination
US20060253100A1 (en) * 2004-10-22 2006-11-09 Medtronic, Inc. Systems and Methods to Treat Pain Locally
CN101119713A (zh) 2004-11-24 2008-02-06 阿尔高克斯制药公司 类辣椒素凝胶制剂及其用途
US7611494B2 (en) 2005-02-08 2009-11-03 Confluent Surgical, Inc. Spray for fluent materials
US20060183786A1 (en) 2005-02-16 2006-08-17 Chi Mei Foundation Hospital Injectable long-acting analgesic composition comprising an ester derivative of ketorolac
US20060211665A1 (en) 2005-03-17 2006-09-21 Ranawat Chitranjan S Reduction of postoperative pain medication
EP1881821B1 (en) 2005-05-20 2016-11-09 Omeros Corporation Compositions comprising ketoprofen and calcium channel antagonist for use in urological procedures
CA2603044A1 (en) 2005-06-29 2007-01-11 Allergan, Inc. Alpha-2 adrenergic agonists for the treatment of pain
US7610100B2 (en) 2005-12-30 2009-10-27 Boston Scientific Neuromodulation Corporation Methods and systems for treating osteoarthritis
US7741273B2 (en) 2006-04-13 2010-06-22 Warsaw Orthopedic, Inc. Drug depot implant designs
US20070253994A1 (en) 2006-04-28 2007-11-01 Medtronic, Inc. Intraspinal Drug Delivery Methods and Devices To Alleviate Chronic Pelvic Pain
WO2008003093A2 (en) 2006-06-29 2008-01-03 Questcor Pharmaceuticals, Inc. Pharmaceutical compositions and related methods of treatment
US20100040609A1 (en) * 2006-07-07 2010-02-18 Gorman James R Methods for preventing, postponing or improving the outcome of invasive spinal procedures
US20080091207A1 (en) 2006-10-13 2008-04-17 Csaba Truckai Bone treatment systems and methods
US20080152709A1 (en) 2006-12-22 2008-06-26 Drugtech Corporation Clonidine composition and method of use
ITBO20070461A1 (it) 2007-07-04 2009-01-05 Dinamica Generale S R L Sistema per controllare il caricamento di uno o piu' alimenti in una unita' semovente di miscelazione tramite una pala meccanica montata su un veicolo a motore
WO2009100441A2 (en) 2008-02-08 2009-08-13 Impax Laboratories, Inc. Depot formulations

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