JP2011507487A5 - - Google Patents
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- Publication number
- JP2011507487A5 JP2011507487A5 JP2010528468A JP2010528468A JP2011507487A5 JP 2011507487 A5 JP2011507487 A5 JP 2011507487A5 JP 2010528468 A JP2010528468 A JP 2010528468A JP 2010528468 A JP2010528468 A JP 2010528468A JP 2011507487 A5 JP2011507487 A5 JP 2011507487A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- homodimer
- acid sequence
- pharmaceutical composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001184 polypeptide Polymers 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 239000000710 homodimer Substances 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 150000007523 nucleic acids Chemical group 0.000 claims 5
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 4
- 102000018997 Growth Hormone Human genes 0.000 claims 2
- 108010051696 Growth Hormone Proteins 0.000 claims 2
- 229940124013 Growth hormone receptor antagonist Drugs 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 239000000122 growth hormone Substances 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 206010000599 Acromegaly Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 230000003442 weekly effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97901007P | 2007-10-10 | 2007-10-10 | |
| US60/979,010 | 2007-10-10 | ||
| GBGB0719818.7A GB0719818D0 (en) | 2007-10-11 | 2007-10-11 | Growth hormone fusion polypeptides |
| GB0719818.7 | 2007-10-11 | ||
| PCT/GB2008/003056 WO2009047474A2 (en) | 2007-10-10 | 2008-09-10 | Modified growth hormone polypeptides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011507487A JP2011507487A (ja) | 2011-03-10 |
| JP2011507487A5 true JP2011507487A5 (enExample) | 2011-10-27 |
| JP5697983B2 JP5697983B2 (ja) | 2015-04-08 |
Family
ID=38787949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010528468A Expired - Fee Related JP5697983B2 (ja) | 2007-10-10 | 2008-09-10 | 修飾成長ホルモンポリペプチド |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8273552B2 (enExample) |
| EP (2) | EP2886553A1 (enExample) |
| JP (1) | JP5697983B2 (enExample) |
| KR (1) | KR20100067686A (enExample) |
| CN (1) | CN101932600B (enExample) |
| AR (1) | AR068038A1 (enExample) |
| AU (1) | AU2008309386A1 (enExample) |
| BR (1) | BRPI0818639A2 (enExample) |
| CA (1) | CA2701369A1 (enExample) |
| DK (1) | DK2209798T3 (enExample) |
| ES (1) | ES2532600T3 (enExample) |
| GB (1) | GB0719818D0 (enExample) |
| IL (1) | IL203073A0 (enExample) |
| MX (1) | MX2010003892A (enExample) |
| RU (1) | RU2471808C2 (enExample) |
| TW (1) | TW200918098A (enExample) |
| WO (1) | WO2009047474A2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0606946D0 (en) * | 2006-04-06 | 2006-05-17 | Asterion Ltd | Polypeptide antagonist |
| GB201104285D0 (en) * | 2011-03-15 | 2011-04-27 | Asterion Ltd | Modified receptor fusion proteins |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH20A (fr) * | 1888-12-05 | Joseph Magnat | Une pompe à bière automatique fonctionnant par la pression de l'eau | |
| DE851925T1 (de) * | 1995-09-21 | 2003-08-14 | Genentech Inc., San Francisco | Varianten des menschlichen wachstumshormons |
| GB0018891D0 (en) * | 2000-08-01 | 2000-09-20 | Novartis Ag | Organic compounds |
| EP1290170A2 (en) * | 2000-06-16 | 2003-03-12 | Asterion Limited | Binding agents: chimeric ligand/receptor proteins |
| EP1456398B1 (en) * | 2001-11-21 | 2011-05-11 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Recovery of recombinant human parainfluenza virus type 1 (hpivi) from cdna |
| GB2389115B (en) * | 2001-12-14 | 2005-03-16 | Asterion Ltd | Polypeptide having a plurality of modified growth hormone receptor binding domains of growth hormone |
| US7625998B2 (en) * | 2003-04-09 | 2009-12-01 | Asterion Limited | Cytokine polypeptides and antibodies containing a signal sequence for the attachment of glycosylphosphatidylinositol |
| US20090221477A1 (en) * | 2004-07-26 | 2009-09-03 | Asterion Limited | Linkers |
| GB0717985D0 (en) * | 2007-07-20 | 2007-10-24 | Asterion Ltd | Growth hormone fusion proteins |
| JP2011512134A (ja) * | 2008-02-19 | 2011-04-21 | アステリオン・リミテッド | 修飾リンカー |
-
2007
- 2007-10-11 GB GBGB0719818.7A patent/GB0719818D0/en not_active Ceased
-
2008
- 2008-08-20 TW TW097131758A patent/TW200918098A/zh unknown
- 2008-08-26 AR ARP080103700A patent/AR068038A1/es not_active Application Discontinuation
- 2008-09-10 EP EP14197613.4A patent/EP2886553A1/en not_active Withdrawn
- 2008-09-10 WO PCT/GB2008/003056 patent/WO2009047474A2/en not_active Ceased
- 2008-09-10 CN CN200880106595.1A patent/CN101932600B/zh not_active Expired - Fee Related
- 2008-09-10 BR BRPI0818639 patent/BRPI0818639A2/pt not_active Application Discontinuation
- 2008-09-10 KR KR1020107010215A patent/KR20100067686A/ko not_active Ceased
- 2008-09-10 ES ES08788565.3T patent/ES2532600T3/es active Active
- 2008-09-10 MX MX2010003892A patent/MX2010003892A/es not_active Application Discontinuation
- 2008-09-10 EP EP08788565.3A patent/EP2209798B1/en not_active Not-in-force
- 2008-09-10 DK DK08788565T patent/DK2209798T3/en active
- 2008-09-10 AU AU2008309386A patent/AU2008309386A1/en not_active Abandoned
- 2008-09-10 JP JP2010528468A patent/JP5697983B2/ja not_active Expired - Fee Related
- 2008-09-10 CA CA2701369A patent/CA2701369A1/en not_active Abandoned
- 2008-09-10 US US12/678,282 patent/US8273552B2/en not_active Expired - Fee Related
- 2008-09-10 RU RU2010103159/10A patent/RU2471808C2/ru not_active IP Right Cessation
-
2009
- 2009-12-31 IL IL203073A patent/IL203073A0/en unknown
-
2012
- 2012-08-22 US US13/592,252 patent/US20120322735A1/en not_active Abandoned