RU2471808C2 - Полипептиды модифицированного гормона роста - Google Patents
Полипептиды модифицированного гормона роста Download PDFInfo
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- RU2471808C2 RU2471808C2 RU2010103159/10A RU2010103159A RU2471808C2 RU 2471808 C2 RU2471808 C2 RU 2471808C2 RU 2010103159/10 A RU2010103159/10 A RU 2010103159/10A RU 2010103159 A RU2010103159 A RU 2010103159A RU 2471808 C2 RU2471808 C2 RU 2471808C2
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- 210000004881 tumor cell Anatomy 0.000 description 1
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 description 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 description 1
- 210000002229 urogenital system Anatomy 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97901007P | 2007-10-10 | 2007-10-10 | |
| US60/979,010 | 2007-10-10 | ||
| GBGB0719818.7A GB0719818D0 (en) | 2007-10-11 | 2007-10-11 | Growth hormone fusion polypeptides |
| GB0719818.7 | 2007-10-11 | ||
| PCT/GB2008/003056 WO2009047474A2 (en) | 2007-10-10 | 2008-09-10 | Modified growth hormone polypeptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2010103159A RU2010103159A (ru) | 2011-11-20 |
| RU2471808C2 true RU2471808C2 (ru) | 2013-01-10 |
Family
ID=38787949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2010103159/10A RU2471808C2 (ru) | 2007-10-10 | 2008-09-10 | Полипептиды модифицированного гормона роста |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US8273552B2 (enExample) |
| EP (2) | EP2886553A1 (enExample) |
| JP (1) | JP5697983B2 (enExample) |
| KR (1) | KR20100067686A (enExample) |
| CN (1) | CN101932600B (enExample) |
| AR (1) | AR068038A1 (enExample) |
| AU (1) | AU2008309386A1 (enExample) |
| BR (1) | BRPI0818639A2 (enExample) |
| CA (1) | CA2701369A1 (enExample) |
| DK (1) | DK2209798T3 (enExample) |
| ES (1) | ES2532600T3 (enExample) |
| GB (1) | GB0719818D0 (enExample) |
| IL (1) | IL203073A0 (enExample) |
| MX (1) | MX2010003892A (enExample) |
| RU (1) | RU2471808C2 (enExample) |
| TW (1) | TW200918098A (enExample) |
| WO (1) | WO2009047474A2 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0606946D0 (en) * | 2006-04-06 | 2006-05-17 | Asterion Ltd | Polypeptide antagonist |
| GB201104285D0 (en) * | 2011-03-15 | 2011-04-27 | Asterion Ltd | Modified receptor fusion proteins |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH20A (fr) * | 1888-12-05 | Joseph Magnat | Une pompe à bière automatique fonctionnant par la pression de l'eau | |
| WO2001096565A2 (en) * | 2000-06-16 | 2001-12-20 | Asterion Limited | Binding agents: chimeric ligand/receptor proteins |
| WO2004090135A2 (en) * | 2003-04-09 | 2004-10-21 | Asterion Limited | Cytokine polypeptides and antibodies containing a signal sequence for the attachement of glycosylphosphatidylinositol |
| RU2287533C2 (ru) * | 2000-08-01 | 2006-11-20 | Новартис Аг | Аналоги соматостатина |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE851925T1 (de) * | 1995-09-21 | 2003-08-14 | Genentech Inc., San Francisco | Varianten des menschlichen wachstumshormons |
| EP1456398B1 (en) * | 2001-11-21 | 2011-05-11 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Recovery of recombinant human parainfluenza virus type 1 (hpivi) from cdna |
| GB2389115B (en) * | 2001-12-14 | 2005-03-16 | Asterion Ltd | Polypeptide having a plurality of modified growth hormone receptor binding domains of growth hormone |
| US20090221477A1 (en) * | 2004-07-26 | 2009-09-03 | Asterion Limited | Linkers |
| GB0717985D0 (en) * | 2007-07-20 | 2007-10-24 | Asterion Ltd | Growth hormone fusion proteins |
| JP2011512134A (ja) * | 2008-02-19 | 2011-04-21 | アステリオン・リミテッド | 修飾リンカー |
-
2007
- 2007-10-11 GB GBGB0719818.7A patent/GB0719818D0/en not_active Ceased
-
2008
- 2008-08-20 TW TW097131758A patent/TW200918098A/zh unknown
- 2008-08-26 AR ARP080103700A patent/AR068038A1/es not_active Application Discontinuation
- 2008-09-10 EP EP14197613.4A patent/EP2886553A1/en not_active Withdrawn
- 2008-09-10 WO PCT/GB2008/003056 patent/WO2009047474A2/en not_active Ceased
- 2008-09-10 CN CN200880106595.1A patent/CN101932600B/zh not_active Expired - Fee Related
- 2008-09-10 BR BRPI0818639 patent/BRPI0818639A2/pt not_active Application Discontinuation
- 2008-09-10 KR KR1020107010215A patent/KR20100067686A/ko not_active Ceased
- 2008-09-10 ES ES08788565.3T patent/ES2532600T3/es active Active
- 2008-09-10 MX MX2010003892A patent/MX2010003892A/es not_active Application Discontinuation
- 2008-09-10 EP EP08788565.3A patent/EP2209798B1/en not_active Not-in-force
- 2008-09-10 DK DK08788565T patent/DK2209798T3/en active
- 2008-09-10 AU AU2008309386A patent/AU2008309386A1/en not_active Abandoned
- 2008-09-10 JP JP2010528468A patent/JP5697983B2/ja not_active Expired - Fee Related
- 2008-09-10 CA CA2701369A patent/CA2701369A1/en not_active Abandoned
- 2008-09-10 US US12/678,282 patent/US8273552B2/en not_active Expired - Fee Related
- 2008-09-10 RU RU2010103159/10A patent/RU2471808C2/ru not_active IP Right Cessation
-
2009
- 2009-12-31 IL IL203073A patent/IL203073A0/en unknown
-
2012
- 2012-08-22 US US13/592,252 patent/US20120322735A1/en not_active Abandoned
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH20A (fr) * | 1888-12-05 | Joseph Magnat | Une pompe à bière automatique fonctionnant par la pression de l'eau | |
| WO2001096565A2 (en) * | 2000-06-16 | 2001-12-20 | Asterion Limited | Binding agents: chimeric ligand/receptor proteins |
| RU2287533C2 (ru) * | 2000-08-01 | 2006-11-20 | Новартис Аг | Аналоги соматостатина |
| WO2004090135A2 (en) * | 2003-04-09 | 2004-10-21 | Asterion Limited | Cytokine polypeptides and antibodies containing a signal sequence for the attachement of glycosylphosphatidylinositol |
Non-Patent Citations (3)
| Title |
|---|
| PRADHANANGA S.L. ET AL., TANDEM FUSIONS OF GROWTH HORMONE AND ITS G120R MUTATED ANTAGONIST RETAIN BIOLOGICAL ACTIVITY AND DEMONSTRATE PROLONGED PLASMA HALF-LIFE, GROWTH HORMONE AND IGF RESEARCH, 2004, v.14, n.2, p.116. * |
| Последовательность под N NRP-HC000388, размещенная 22.07.2004 в БД "FASTA EBI.AC.UK". * |
| Последовательность под N NRP-HC000388, размещенная 22.07.2004 в БД "FASTA EBI.AC.UK". PRADHANANGA S.L. ET AL., TANDEM FUSIONS OF GROWTH HORMONE AND ITS G120R MUTATED ANTAGONIST RETAIN BIOLOGICAL ACTIVITY AND DEMONSTRATE PROLONGED PLASMA HALF-LIFE, GROWTH HORMONE AND IGF RESEAR n.2, p.116. * |
Also Published As
| Publication number | Publication date |
|---|---|
| AR068038A1 (es) | 2009-10-28 |
| RU2010103159A (ru) | 2011-11-20 |
| EP2886553A1 (en) | 2015-06-24 |
| US20120322735A1 (en) | 2012-12-20 |
| KR20100067686A (ko) | 2010-06-21 |
| TW200918098A (en) | 2009-05-01 |
| WO2009047474A2 (en) | 2009-04-16 |
| MX2010003892A (es) | 2010-05-17 |
| GB0719818D0 (en) | 2007-11-21 |
| DK2209798T3 (en) | 2015-03-23 |
| EP2209798B1 (en) | 2014-12-31 |
| ES2532600T3 (es) | 2015-03-30 |
| CN101932600B (zh) | 2014-05-28 |
| IL203073A0 (en) | 2010-11-30 |
| EP2209798A2 (en) | 2010-07-28 |
| BRPI0818639A2 (pt) | 2015-04-07 |
| WO2009047474A3 (en) | 2010-09-02 |
| JP5697983B2 (ja) | 2015-04-08 |
| CA2701369A1 (en) | 2009-04-16 |
| CN101932600A (zh) | 2010-12-29 |
| AU2008309386A1 (en) | 2009-04-16 |
| JP2011507487A (ja) | 2011-03-10 |
| US8273552B2 (en) | 2012-09-25 |
| US20100197589A1 (en) | 2010-08-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20140911 |