KR20100067686A - 변형된 성장 호르몬 폴리펩티드 - Google Patents

변형된 성장 호르몬 폴리펩티드 Download PDF

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Publication number
KR20100067686A
KR20100067686A KR1020107010215A KR20107010215A KR20100067686A KR 20100067686 A KR20100067686 A KR 20100067686A KR 1020107010215 A KR1020107010215 A KR 1020107010215A KR 20107010215 A KR20107010215 A KR 20107010215A KR 20100067686 A KR20100067686 A KR 20100067686A
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KR
South Korea
Prior art keywords
seq
ser
leu
glu
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020107010215A
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English (en)
Korean (ko)
Inventor
피터 아르티미우크
리차드 에이 로스
존 사이어스
Original Assignee
아스테리온 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 아스테리온 리미티드 filed Critical 아스테리온 리미티드
Publication of KR20100067686A publication Critical patent/KR20100067686A/ko
Ceased legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A61P5/08Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020107010215A 2007-10-10 2008-09-10 변형된 성장 호르몬 폴리펩티드 Ceased KR20100067686A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US97901007P 2007-10-10 2007-10-10
US60/979,010 2007-10-10
GBGB0719818.7A GB0719818D0 (en) 2007-10-11 2007-10-11 Growth hormone fusion polypeptides
GB0719818.7 2007-10-11

Publications (1)

Publication Number Publication Date
KR20100067686A true KR20100067686A (ko) 2010-06-21

Family

ID=38787949

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020107010215A Ceased KR20100067686A (ko) 2007-10-10 2008-09-10 변형된 성장 호르몬 폴리펩티드

Country Status (17)

Country Link
US (2) US8273552B2 (enExample)
EP (2) EP2886553A1 (enExample)
JP (1) JP5697983B2 (enExample)
KR (1) KR20100067686A (enExample)
CN (1) CN101932600B (enExample)
AR (1) AR068038A1 (enExample)
AU (1) AU2008309386A1 (enExample)
BR (1) BRPI0818639A2 (enExample)
CA (1) CA2701369A1 (enExample)
DK (1) DK2209798T3 (enExample)
ES (1) ES2532600T3 (enExample)
GB (1) GB0719818D0 (enExample)
IL (1) IL203073A0 (enExample)
MX (1) MX2010003892A (enExample)
RU (1) RU2471808C2 (enExample)
TW (1) TW200918098A (enExample)
WO (1) WO2009047474A2 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0606946D0 (en) * 2006-04-06 2006-05-17 Asterion Ltd Polypeptide antagonist
GB201104285D0 (en) * 2011-03-15 2011-04-27 Asterion Ltd Modified receptor fusion proteins

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH20A (fr) * 1888-12-05 Joseph Magnat Une pompe à bière automatique fonctionnant par la pression de l'eau
DE851925T1 (de) * 1995-09-21 2003-08-14 Genentech Inc., San Francisco Varianten des menschlichen wachstumshormons
GB0018891D0 (en) * 2000-08-01 2000-09-20 Novartis Ag Organic compounds
EP1290170A2 (en) * 2000-06-16 2003-03-12 Asterion Limited Binding agents: chimeric ligand/receptor proteins
EP1456398B1 (en) * 2001-11-21 2011-05-11 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Recovery of recombinant human parainfluenza virus type 1 (hpivi) from cdna
GB2389115B (en) * 2001-12-14 2005-03-16 Asterion Ltd Polypeptide having a plurality of modified growth hormone receptor binding domains of growth hormone
US7625998B2 (en) * 2003-04-09 2009-12-01 Asterion Limited Cytokine polypeptides and antibodies containing a signal sequence for the attachment of glycosylphosphatidylinositol
US20090221477A1 (en) * 2004-07-26 2009-09-03 Asterion Limited Linkers
GB0717985D0 (en) * 2007-07-20 2007-10-24 Asterion Ltd Growth hormone fusion proteins
JP2011512134A (ja) * 2008-02-19 2011-04-21 アステリオン・リミテッド 修飾リンカー

Also Published As

Publication number Publication date
RU2471808C2 (ru) 2013-01-10
AR068038A1 (es) 2009-10-28
RU2010103159A (ru) 2011-11-20
EP2886553A1 (en) 2015-06-24
US20120322735A1 (en) 2012-12-20
TW200918098A (en) 2009-05-01
WO2009047474A2 (en) 2009-04-16
MX2010003892A (es) 2010-05-17
GB0719818D0 (en) 2007-11-21
DK2209798T3 (en) 2015-03-23
EP2209798B1 (en) 2014-12-31
ES2532600T3 (es) 2015-03-30
CN101932600B (zh) 2014-05-28
IL203073A0 (en) 2010-11-30
EP2209798A2 (en) 2010-07-28
BRPI0818639A2 (pt) 2015-04-07
WO2009047474A3 (en) 2010-09-02
JP5697983B2 (ja) 2015-04-08
CA2701369A1 (en) 2009-04-16
CN101932600A (zh) 2010-12-29
AU2008309386A1 (en) 2009-04-16
JP2011507487A (ja) 2011-03-10
US8273552B2 (en) 2012-09-25
US20100197589A1 (en) 2010-08-05

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