JP2011506511A - 副作用を軽減または防止するためのボツリヌス菌毒素複合体の神経毒成分の使用 - Google Patents
副作用を軽減または防止するためのボツリヌス菌毒素複合体の神経毒成分の使用 Download PDFInfo
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Classifications
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
- A61K38/4893—Botulinum neurotoxin (3.4.24.69)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Neurosurgery (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US901007P | 2007-12-21 | 2007-12-21 | |
| EP07024961A EP2072039A1 (en) | 2007-12-21 | 2007-12-21 | Use of a neurotoxic component of Clostridium botulinum toxin complex to reduce or prevent side effects |
| PCT/EP2008/010782 WO2009080272A1 (en) | 2007-12-21 | 2008-12-17 | Use of a neurotoxic component of a clostridium botulinum toxin complex to reduce or prevent side effects |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011506511A true JP2011506511A (ja) | 2011-03-03 |
| JP2011506511A5 JP2011506511A5 (enExample) | 2012-01-05 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010538453A Pending JP2011506511A (ja) | 2007-12-21 | 2008-12-17 | 副作用を軽減または防止するためのボツリヌス菌毒素複合体の神経毒成分の使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20100331259A1 (enExample) |
| EP (2) | EP2072039A1 (enExample) |
| JP (1) | JP2011506511A (enExample) |
| KR (1) | KR20100107475A (enExample) |
| CN (1) | CN101917960A (enExample) |
| AR (1) | AR069806A1 (enExample) |
| AU (1) | AU2008340713A1 (enExample) |
| CA (1) | CA2709644A1 (enExample) |
| IL (1) | IL206423A0 (enExample) |
| MX (1) | MX2010006731A (enExample) |
| RU (1) | RU2010130542A (enExample) |
| WO (1) | WO2009080272A1 (enExample) |
| ZA (1) | ZA201004393B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016540785A (ja) * | 2013-12-12 | 2016-12-28 | メディ−トックス インク | 新しいボツリヌス毒素製剤の長期持続作用 |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10792344B2 (en) * | 2006-06-29 | 2020-10-06 | Merz Pharma Gmbh & Co. Kgaa | High frequency application of botulinum toxin therapy |
| US9161970B2 (en) * | 2007-12-12 | 2015-10-20 | Allergan, Inc. | Dermal filler |
| US11484580B2 (en) | 2014-07-18 | 2022-11-01 | Revance Therapeutics, Inc. | Topical ocular preparation of botulinum toxin for use in ocular surface disease |
| US9901627B2 (en) | 2014-07-18 | 2018-02-27 | Revance Therapeutics, Inc. | Topical ocular preparation of botulinum toxin for use in ocular surface disease |
| WO2018146550A1 (en) * | 2017-02-10 | 2018-08-16 | De Maio Domingos Mauricio | Methods and systems for preventing, correcting, transforming, and modifying facial, aesthetics, and consulting patients regarding the same |
| DE102019215585B4 (de) * | 2019-10-10 | 2022-02-17 | KCM Egészségügyi és Tudományos Korlátolt Felelösségü Társaság | Verfahren zur prävention von strahlenschäden in humanen drüsen |
| US11241479B2 (en) | 2019-10-18 | 2022-02-08 | Penland Foundation | Treatment methods using botulinum toxins |
| US10973873B1 (en) | 2019-10-18 | 2021-04-13 | Penland Foundation | Treatment of asthma using botulinum toxin |
| US11090371B1 (en) * | 2019-10-18 | 2021-08-17 | Penland Foundation | Treatment of cirrhosis using botulinum toxin |
| US11925677B2 (en) | 2021-07-12 | 2024-03-12 | Penland Foundation | Treatment of diabetes and chronic pancreatitis using botulinum toxin |
| US10967052B1 (en) | 2019-10-18 | 2021-04-06 | Penland Foundation | Treatment of dyslexia using botulinum toxin |
| AU2020365148B2 (en) | 2019-10-18 | 2022-10-27 | Penland Foundation | Botulinum toxin for use in treatment |
| US11738071B2 (en) | 2021-07-12 | 2023-08-29 | Penland Foundation | Treatment of acute and chronic kidney disease |
| US10987411B1 (en) | 2019-10-18 | 2021-04-27 | Penland Foundation | Treatment of chronic obstructive pulmonary disease using botulinum toxin |
| US10960061B1 (en) * | 2019-10-18 | 2021-03-30 | Penland Foundation | Treatment of amyotrophic lateral sclerosis using botulinum toxin |
| US10960060B1 (en) | 2019-10-18 | 2021-03-30 | Penland Foundation | Treatment of cardiac arrhythmia using botulinum toxin |
| KR102397708B1 (ko) * | 2020-04-29 | 2022-05-16 | 한국화학연구원 | 탄닌산을 포함하는 보툴리눔 독소 약제학적 조성물 |
| CN116096399A (zh) * | 2020-06-03 | 2023-05-09 | 米奥托克斯有限责任公司 | 用于治疗偏头痛病症的区带性和靶向方法和用途 |
| IL298399A (en) * | 2020-06-05 | 2023-01-01 | Merz Pharma Gmbh & Co Kgaa | Treatment of facial wrinkles with the botulinum toxin in high dose and low volume |
| KR102724650B1 (ko) | 2021-07-05 | 2024-11-01 | 주식회사 파마리서치바이오 | 클로스트리디움 보툴리눔 독소 복합체 단백질의 정제방법 |
| KR102724651B1 (ko) | 2021-07-08 | 2024-11-01 | 주식회사 파마리서치바이오 | 비-독소 단백질이 제거된 클로스트리디움 보툴리눔 신경독소 단백질의 정제방법 |
| KR102551301B1 (ko) | 2022-10-28 | 2023-07-03 | 주식회사 파마리서치바이오 | 보툴리눔 독소를 포함하는 안정한 액상 제제 |
Citations (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH09507234A (ja) * | 1993-12-28 | 1997-07-22 | アラーガン | 種々の疾病およびそれに伴う疼痛を処置するためのボツリヌス毒素 |
| JPH11507072A (ja) * | 1996-03-27 | 1999-06-22 | ウイスコンシン アラムナイ リサーチ フオンデーシヨン | ボツリヌス毒素またはボツリヌス神経毒の薬学的組成物および製造方法 |
| JP2003505343A (ja) * | 1999-06-07 | 2003-02-12 | メルツ・ウント・コンパニー・ゲゼルシヤフト・ミト・ベシュレンクテル・ハフツング・ウント・コンパニー | ボツリヌス神経毒を含む治療薬 |
| WO2003082315A1 (fr) * | 2002-03-29 | 2003-10-09 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Remede contre l'hypermyotonie |
| US20040115222A1 (en) * | 2002-09-06 | 2004-06-17 | Michael Kane | Method for reduction of wrinkles |
| US20040126397A1 (en) * | 1993-12-28 | 2004-07-01 | Allergan, Inc. | Use of the neurotoxic component of a botulinum toxin for treating various disorders and conditions and associated pain |
| JP2005089336A (ja) * | 2003-09-12 | 2005-04-07 | Tokyo Univ Of Agriculture | D型ボツリヌス神経毒素の精製法 |
| WO2006020208A2 (en) * | 2004-07-26 | 2006-02-23 | Merz Pharma Gmbh & Co. Kgaa | Therapeutic composition whit a botulinum neurotoxin |
| GB2426702A (en) * | 2004-10-28 | 2006-12-06 | Ipsen Ltd | Pharmaceutical composition comprising botulinum neurotoxin |
| WO2008000490A1 (en) * | 2006-06-29 | 2008-01-03 | Merz Pharma Gmbh & Co. Kgaa | High frequency application of neurotoxic component of botulinum toxin |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5512547A (en) * | 1994-10-13 | 1996-04-30 | Wisconsin Alumni Research Foundation | Pharmaceutical composition of botulinum neurotoxin and method of preparation |
| CA2494241C (en) | 2000-02-08 | 2011-06-14 | Allergan, Inc. | Botulinum toxin pharmaceutical compositions |
| US6503653B2 (en) * | 2001-02-23 | 2003-01-07 | General Motors Corporation | Stamped bipolar plate for PEM fuel cell stack |
| JP3830766B2 (ja) * | 2001-03-09 | 2006-10-11 | 本田技研工業株式会社 | 燃料電池および燃料電池スタック |
| DE102004043009A1 (de) * | 2004-09-06 | 2006-03-23 | Toxogen Gmbh | Transportprotein zum Einbringen chemischer Verbindungen in Nervenzellen |
| DE102005019302A1 (de) | 2005-04-26 | 2006-11-16 | Toxogen Gmbh | Carrier zum Targeting von Nervenzellen |
-
2007
- 2007-12-21 EP EP07024961A patent/EP2072039A1/en not_active Withdrawn
-
2008
- 2008-12-17 US US12/735,144 patent/US20100331259A1/en not_active Abandoned
- 2008-12-17 CN CN2008801218887A patent/CN101917960A/zh active Pending
- 2008-12-17 KR KR1020107016383A patent/KR20100107475A/ko not_active Withdrawn
- 2008-12-17 EP EP08864233A patent/EP2231107A1/en not_active Withdrawn
- 2008-12-17 MX MX2010006731A patent/MX2010006731A/es not_active Application Discontinuation
- 2008-12-17 WO PCT/EP2008/010782 patent/WO2009080272A1/en not_active Ceased
- 2008-12-17 CA CA2709644A patent/CA2709644A1/en not_active Abandoned
- 2008-12-17 JP JP2010538453A patent/JP2011506511A/ja active Pending
- 2008-12-17 RU RU2010130542/15A patent/RU2010130542A/ru not_active Application Discontinuation
- 2008-12-17 AU AU2008340713A patent/AU2008340713A1/en not_active Abandoned
- 2008-12-18 AR ARP080105529A patent/AR069806A1/es not_active Application Discontinuation
-
2010
- 2010-06-16 IL IL206423A patent/IL206423A0/en unknown
- 2010-06-22 ZA ZA2010/04393A patent/ZA201004393B/en unknown
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016540785A (ja) * | 2013-12-12 | 2016-12-28 | メディ−トックス インク | 新しいボツリヌス毒素製剤の長期持続作用 |
| JP2020045360A (ja) * | 2013-12-12 | 2020-03-26 | メディ−トックス インク | 新しいボツリヌス毒素製剤の長期持続作用 |
| JP7121458B2 (ja) | 2013-12-12 | 2022-08-18 | メディトックス インク. | 新しいボツリヌス毒素製剤の長期持続作用 |
| JP2022161932A (ja) * | 2013-12-12 | 2022-10-21 | メディトックス インク. | 新しいボツリヌス毒素製剤の長期持続作用 |
| JP7439187B2 (ja) | 2013-12-12 | 2024-02-27 | メディトックス インク. | 新しいボツリヌス毒素製剤の長期持続作用 |
Also Published As
| Publication number | Publication date |
|---|---|
| MX2010006731A (es) | 2010-08-16 |
| AR069806A1 (es) | 2010-02-17 |
| IL206423A0 (en) | 2010-12-30 |
| KR20100107475A (ko) | 2010-10-05 |
| CN101917960A (zh) | 2010-12-15 |
| CA2709644A1 (en) | 2009-07-02 |
| AU2008340713A1 (en) | 2009-07-02 |
| EP2231107A1 (en) | 2010-09-29 |
| EP2072039A1 (en) | 2009-06-24 |
| RU2010130542A (ru) | 2012-01-27 |
| ZA201004393B (en) | 2011-08-31 |
| WO2009080272A1 (en) | 2009-07-02 |
| US20100331259A1 (en) | 2010-12-30 |
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