JP2011500617A5 - - Google Patents
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- JP2011500617A5 JP2011500617A5 JP2010529300A JP2010529300A JP2011500617A5 JP 2011500617 A5 JP2011500617 A5 JP 2011500617A5 JP 2010529300 A JP2010529300 A JP 2010529300A JP 2010529300 A JP2010529300 A JP 2010529300A JP 2011500617 A5 JP2011500617 A5 JP 2011500617A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- plasminogen activator
- stroke
- patient
- patients
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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- 229940127126 plasminogen activator Drugs 0.000 claims description 56
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- 108010001014 Plasminogen Activators Proteins 0.000 claims description 55
- 238000011282 treatment Methods 0.000 claims description 45
- 239000000203 mixture Substances 0.000 claims description 24
- 206010061216 Infarction Diseases 0.000 claims description 23
- 230000007574 infarction Effects 0.000 claims description 23
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Images
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07020401.1 | 2007-10-18 | ||
| EP07020401A EP2050462A1 (en) | 2007-10-18 | 2007-10-18 | Improved treatment of stroke patients |
| EP07022867.1 | 2007-11-26 | ||
| EP07022867 | 2007-11-26 | ||
| EP08017954.2 | 2008-10-15 | ||
| EP08017954 | 2008-10-15 | ||
| PCT/EP2008/008871 WO2009049914A2 (en) | 2007-10-18 | 2008-10-20 | Novel patient subgroups for thrombolysis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014000825A Division JP2014065739A (ja) | 2007-10-18 | 2014-01-07 | 血栓溶解についての新規な患者亜群 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011500617A JP2011500617A (ja) | 2011-01-06 |
| JP2011500617A5 true JP2011500617A5 (https=) | 2012-08-16 |
| JP5509085B2 JP5509085B2 (ja) | 2014-06-04 |
Family
ID=40567844
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010529300A Expired - Fee Related JP5509085B2 (ja) | 2007-10-18 | 2008-10-20 | 血栓溶解についての新規な患者亜群 |
| JP2014000825A Withdrawn JP2014065739A (ja) | 2007-10-18 | 2014-01-07 | 血栓溶解についての新規な患者亜群 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014000825A Withdrawn JP2014065739A (ja) | 2007-10-18 | 2014-01-07 | 血栓溶解についての新規な患者亜群 |
Country Status (28)
| Country | Link |
|---|---|
| US (2) | US20100272704A1 (https=) |
| EP (1) | EP2211898B1 (https=) |
| JP (2) | JP5509085B2 (https=) |
| KR (1) | KR20100089077A (https=) |
| CN (1) | CN101903039B (https=) |
| AR (1) | AR068914A1 (https=) |
| AU (1) | AU2008314048B2 (https=) |
| BR (1) | BRPI0817785A2 (https=) |
| CA (1) | CA2702378A1 (https=) |
| CL (1) | CL2009000752A1 (https=) |
| CY (1) | CY1118417T1 (https=) |
| DK (1) | DK2211898T3 (https=) |
| EA (1) | EA020776B1 (https=) |
| ES (1) | ES2611155T3 (https=) |
| HR (1) | HRP20170001T1 (https=) |
| HU (1) | HUE032867T2 (https=) |
| IL (1) | IL205175A0 (https=) |
| LT (1) | LT2211898T (https=) |
| MX (1) | MX2010004157A (https=) |
| MY (1) | MY159200A (https=) |
| NZ (1) | NZ584640A (https=) |
| PL (1) | PL2211898T3 (https=) |
| PT (1) | PT2211898T (https=) |
| RS (1) | RS55590B1 (https=) |
| SI (1) | SI2211898T1 (https=) |
| TW (1) | TWI482628B (https=) |
| WO (1) | WO2009049914A2 (https=) |
| ZA (1) | ZA201002548B (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10153601A1 (de) * | 2001-11-02 | 2003-05-22 | Paion Gmbh | DSPA zur Behandlung von Schlaganfall |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4766075A (en) * | 1982-07-14 | 1988-08-23 | Genentech, Inc. | Human tissue plasminogen activator |
| US5244806A (en) * | 1985-08-26 | 1993-09-14 | Eli Lilly And Company | DNA encoding novel tissue plasminogen activator derivatives having kringles 1 and 2 deleted, vectors and host cells |
| IL87276A (en) * | 1987-08-03 | 1995-07-31 | Fujisawa Pharmaceutical Co | Analog of tissue plasminogen activator comprising only the kringle 2 and protease domain dna encoding the same processes for the preparation thereof and pharmaceutical compositions containing the same |
| US5094953A (en) * | 1988-03-21 | 1992-03-10 | Genentech, Inc. | Human tissue plasminogen activator variants |
| DK176140B1 (da) * | 1988-07-20 | 2006-09-25 | Schering Ag Patentabteilung | Flagermusspyt-plasminogenaktivatorer |
| US5714145A (en) * | 1988-09-02 | 1998-02-03 | Genentech, Inc. | Tissue plasminogen activator having zymogenic or fibrin specific properties |
| US5676947A (en) * | 1989-02-07 | 1997-10-14 | Boehringer Manneheim Gmbh | Method for treating thromboembolic conditions using thrombolytically active proteins |
| DE3903581A1 (de) * | 1989-02-07 | 1990-08-16 | Boehringer Mannheim Gmbh | Gewebs-plasminogenaktivator-derivat |
| US6008019A (en) * | 1989-02-13 | 1999-12-28 | Schering Aktiengesellschaft | Plasminogen activator from saliva of the vampire bat |
| US5891664A (en) * | 1989-04-07 | 1999-04-06 | Cancerforskningsfondet Af 1989 | Vectors and methods for recombinant production of uPA-binding fragments of the human urokinase-type plasminogen receptor (uPAR) |
| US5326700A (en) * | 1990-11-06 | 1994-07-05 | Eli Lilly And Company | DNA sequences encoding t-PA derivatives with cleavable sites |
| DE59204945D1 (de) * | 1991-04-16 | 1996-02-15 | Boehringer Mannheim Gmbh | Pharmazeutische verpackungseinheit enthaltend plasminogenaktivatoren zur mehrfachbolusgabe |
| US5595736A (en) * | 1991-04-22 | 1997-01-21 | Eli Lilly And Company | Compounds and methods for treatment of thromboembolic disorders |
| ES2107790T3 (es) * | 1992-12-04 | 1997-12-01 | Schering Ag | Inhibidor de trombina procedente de la saliva de protostomias. |
| US5510330A (en) * | 1994-03-25 | 1996-04-23 | Boehringer Mannheim Gmbh | Combinations of thrombolytically active proteins and non-heparin anticoagulants, and uses thereof. |
| GB9412131D0 (en) * | 1994-06-17 | 1994-08-10 | British Bio Technology | Thrombolytic composition |
| US5827832A (en) * | 1995-03-06 | 1998-10-27 | Interneuron Pharmaceuticals, Inc. | Method of protecting brain tissue from cerebral infarction subsequent to ischemia |
| US5786187A (en) * | 1995-09-21 | 1998-07-28 | The Research Foundation Of State University Of New York | Method for reducing neuronal degeneration associated with seizure |
| US5945432A (en) * | 1995-12-22 | 1999-08-31 | The University Of Vermont And State Agricultural College | Thrombolytic agents and thienopyridine derivatives in acute stroke |
| US20020081294A1 (en) * | 1996-01-23 | 2002-06-27 | Genentech, Inc. | Co-administration of a thrombolytic and an anti-CD18 antibody in stroke |
| US5731186A (en) * | 1996-02-05 | 1998-03-24 | Schering Aktiengesellschaft | Method for the production of rDSPA α1 |
| US6354999B1 (en) * | 2000-01-14 | 2002-03-12 | Florence Medical Ltd. | System and method for detecting, localizing, and characterizing occlusions and aneurysms in a vessel |
| GB0025473D0 (en) * | 2000-10-17 | 2000-11-29 | Pfizer Ltd | Pharmaceutical combinations |
| DE10153601A1 (de) * | 2001-11-02 | 2003-05-22 | Paion Gmbh | DSPA zur Behandlung von Schlaganfall |
| US20060135425A1 (en) * | 2003-05-02 | 2006-06-22 | Paion Deutschland Gmbh | Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke |
| US20080057050A1 (en) * | 2003-05-02 | 2008-03-06 | Paion Deutschland Gmbh | Intravenous injection of plasminogen non-neurotoxic activators for treating cerebral stroke |
| US20080213244A1 (en) * | 2003-05-05 | 2008-09-04 | Wolfgang Sohngen | Glutamate Receptor Antagonists as Neuroprotectives |
| US20050085478A1 (en) * | 2003-08-22 | 2005-04-21 | Pharmacia Corporation | Compositions of a cyclooxygenase-2 selective inhibitor and a low-molecular-weight heparin for the treatment of central nervous system damage |
| CN101248083A (zh) * | 2005-08-25 | 2008-08-20 | 比奥根艾迪克Ma公司 | Nogo受体多肽和多肽片段及其用途 |
-
2008
- 2008-10-17 AR ARP080104540A patent/AR068914A1/es unknown
- 2008-10-17 TW TW097139886A patent/TWI482628B/zh not_active IP Right Cessation
- 2008-10-20 KR KR1020107010609A patent/KR20100089077A/ko not_active Ceased
- 2008-10-20 MY MYPI2010001704A patent/MY159200A/en unknown
- 2008-10-20 MX MX2010004157A patent/MX2010004157A/es active IP Right Grant
- 2008-10-20 PT PT88388970T patent/PT2211898T/pt unknown
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