JP2011239708A5 - - Google Patents
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- JP2011239708A5 JP2011239708A5 JP2010113343A JP2010113343A JP2011239708A5 JP 2011239708 A5 JP2011239708 A5 JP 2011239708A5 JP 2010113343 A JP2010113343 A JP 2010113343A JP 2010113343 A JP2010113343 A JP 2010113343A JP 2011239708 A5 JP2011239708 A5 JP 2011239708A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- standard substance
- acid standard
- detection probe
- probe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000523 sample Substances 0.000 claims 25
- 108020004707 nucleic acids Proteins 0.000 claims 22
- 102000039446 nucleic acids Human genes 0.000 claims 22
- 150000007523 nucleic acids Chemical class 0.000 claims 22
- 238000001514 detection method Methods 0.000 claims 20
- 239000000126 substance Substances 0.000 claims 17
- 238000000034 method Methods 0.000 claims 8
- 108091034117 Oligonucleotide Proteins 0.000 claims 7
- 230000015572 biosynthetic process Effects 0.000 claims 4
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 claims 3
- 108091033319 polynucleotide Proteins 0.000 claims 3
- 102000040430 polynucleotide Human genes 0.000 claims 3
- 239000002157 polynucleotide Substances 0.000 claims 3
- 239000000539 dimer Substances 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 238000010790 dilution Methods 0.000 claims 1
- 239000012895 dilution Substances 0.000 claims 1
- 238000002474 experimental method Methods 0.000 claims 1
- 238000009396 hybridization Methods 0.000 claims 1
- 238000002493 microarray Methods 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010113343A JP2011239708A (ja) | 2010-05-17 | 2010-05-17 | 核酸標準物質検出用プローブの設計方法、核酸標準物質検出用プローブ及び当該核酸標準物質検出用プローブを有する核酸検出系 |
| PCT/JP2011/061310 WO2011145614A1 (ja) | 2010-05-17 | 2011-05-17 | 核酸標準物質検出用プローブの設計方法、核酸標準物質検出用プローブ及び当該核酸標準物質検出用プローブを有する核酸検出系 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010113343A JP2011239708A (ja) | 2010-05-17 | 2010-05-17 | 核酸標準物質検出用プローブの設計方法、核酸標準物質検出用プローブ及び当該核酸標準物質検出用プローブを有する核酸検出系 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011239708A JP2011239708A (ja) | 2011-12-01 |
| JP2011239708A5 true JP2011239708A5 (enExample) | 2013-06-27 |
Family
ID=44991716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010113343A Pending JP2011239708A (ja) | 2010-05-17 | 2010-05-17 | 核酸標準物質検出用プローブの設計方法、核酸標準物質検出用プローブ及び当該核酸標準物質検出用プローブを有する核酸検出系 |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP2011239708A (enExample) |
| WO (1) | WO2011145614A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10233465B2 (en) * | 2013-11-04 | 2019-03-19 | Dow Agrosciences Llc | Optimal soybean loci |
| CN107109397B (zh) * | 2014-11-26 | 2020-11-27 | 东丽株式会社 | 小型rna的表达量的修正方法和装置 |
| US10577643B2 (en) * | 2015-10-07 | 2020-03-03 | Illumina, Inc. | Off-target capture reduction in sequencing techniques |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006217897A (ja) * | 2005-02-14 | 2006-08-24 | Canon Inc | コントロールブローブ用塩基配列及びその設計方法 |
| JP4853898B2 (ja) * | 2005-08-30 | 2012-01-11 | 独立行政法人産業技術総合研究所 | Dna標準物質 |
| JP4772816B2 (ja) * | 2008-03-21 | 2011-09-14 | 株式会社東芝 | マイクロアレイおよびネガティブコントロールプローブの設計方法 |
| JP2009268390A (ja) * | 2008-05-02 | 2009-11-19 | Mitsubishi Rayon Co Ltd | 高感度核酸マイクロアレイ及びその製造方法 |
| JP5229895B2 (ja) * | 2008-11-19 | 2013-07-03 | 独立行政法人産業技術総合研究所 | 核酸標準物質 |
-
2010
- 2010-05-17 JP JP2010113343A patent/JP2011239708A/ja active Pending
-
2011
- 2011-05-17 WO PCT/JP2011/061310 patent/WO2011145614A1/ja not_active Ceased
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