|
US4179337A
(en)
|
1973-07-20 |
1979-12-18 |
Davis Frank F |
Non-immunogenic polypeptides
|
|
US4235871A
(en)
|
1978-02-24 |
1980-11-25 |
Papahadjopoulos Demetrios P |
Method of encapsulating biologically active materials in lipid vesicles
|
|
JPS6023084B2
(ja)
|
1979-07-11 |
1985-06-05 |
味の素株式会社 |
代用血液
|
|
US4640835A
(en)
|
1981-10-30 |
1987-02-03 |
Nippon Chemiphar Company, Ltd. |
Plasminogen activator derivatives
|
|
US4722848A
(en)
|
1982-12-08 |
1988-02-02 |
Health Research, Incorporated |
Method for immunizing animals with synthetically modified vaccinia virus
|
|
US4870009A
(en)
|
1982-11-22 |
1989-09-26 |
The Salk Institute For Biological Studies |
Method of obtaining gene product through the generation of transgenic animals
|
|
US4501728A
(en)
|
1983-01-06 |
1985-02-26 |
Technology Unlimited, Inc. |
Masking of liposomes from RES recognition
|
|
US4496689A
(en)
|
1983-12-27 |
1985-01-29 |
Miles Laboratories, Inc. |
Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
|
|
US4736866B1
(en)
|
1984-06-22 |
1988-04-12 |
|
Transgenic non-human mammals
|
|
US5430136A
(en)
|
1984-10-16 |
1995-07-04 |
Chiron Corporation |
Oligonucleotides having selectably cleavable and/or abasic sites
|
|
US5019369A
(en)
|
1984-10-22 |
1991-05-28 |
Vestar, Inc. |
Method of targeting tumors in humans
|
|
EP0206448B1
(en)
|
1985-06-19 |
1990-11-14 |
Ajinomoto Co., Inc. |
Hemoglobin combined with a poly(alkylene oxide)
|
|
US4791192A
(en)
|
1986-06-26 |
1988-12-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified protein with polyethyleneglycol
|
|
US4837028A
(en)
|
1986-12-24 |
1989-06-06 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US5124246A
(en)
|
1987-10-15 |
1992-06-23 |
Chiron Corporation |
Nucleic acid multimers and amplified nucleic acid hybridization assays using same
|
|
US5359100A
(en)
|
1987-10-15 |
1994-10-25 |
Chiron Corporation |
Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
|
|
GB8724885D0
(en)
|
1987-10-23 |
1987-11-25 |
Binns M M |
Fowlpox virus promotors
|
|
US5254678A
(en)
|
1987-12-15 |
1993-10-19 |
Gene Shears Pty. Limited |
Ribozymes
|
|
CA1340323C
(en)
|
1988-09-20 |
1999-01-19 |
Arnold E. Hampel |
Rna catalyst for cleaving specific rna sequences
|
|
US5225538A
(en)
|
1989-02-23 |
1993-07-06 |
Genentech, Inc. |
Lymphocyte homing receptor/immunoglobulin fusion proteins
|
|
WO1990010448A2
(en)
|
1989-03-07 |
1990-09-20 |
Genentech, Inc. |
Covalent conjugates of lipid and oligonucleotide
|
|
US5703055A
(en)
|
1989-03-21 |
1997-12-30 |
Wisconsin Alumni Research Foundation |
Generation of antibodies through lipid mediated DNA delivery
|
|
WO1991004753A1
(en)
|
1989-10-02 |
1991-04-18 |
Cetus Corporation |
Conjugates of antisense oligonucleotides and therapeutic uses thereof
|
|
EP0452457B1
(en)
|
1989-11-03 |
1997-08-20 |
Vanderbilt University |
Method of in vivo delivery of functioning foreign genes
|
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
EP1690935A3
(en)
|
1990-01-12 |
2008-07-30 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US5279833A
(en)
|
1990-04-04 |
1994-01-18 |
Yale University |
Liposomal transfection of nucleic acids into animal cells
|
|
US5204253A
(en)
|
1990-05-29 |
1993-04-20 |
E. I. Du Pont De Nemours And Company |
Method and apparatus for introducing biological substances into living cells
|
|
US5723286A
(en)
|
1990-06-20 |
1998-03-03 |
Affymax Technologies N.V. |
Peptide library and screening systems
|
|
DE69133528T2
(de)
|
1990-06-27 |
2006-09-07 |
Princeton University |
Proteinkomplex p53/p90
|
|
SE9002480D0
(sv)
|
1990-07-23 |
1990-07-23 |
Hans Lilja |
Assay of free and complexed prostate-specific antigen
|
|
US5733731A
(en)
|
1991-10-16 |
1998-03-31 |
Affymax Technologies N.V. |
Peptide library and screening method
|
|
EP0646178A1
(en)
|
1992-06-04 |
1995-04-05 |
The Regents Of The University Of California |
expression cassette with regularoty regions functional in the mammmlian host
|
|
IL106610A0
(en)
|
1992-08-07 |
1993-12-08 |
Cytel Corp |
Hla binding peptides and their uses
|
|
SG49008A1
(en)
|
1993-03-05 |
1998-05-18 |
Cytel Corp |
Hla-a2.1 binding peptides and their uses
|
|
KR960702518A
(ko)
|
1993-05-17 |
1996-04-27 |
린다 에스, 스티븐슨 |
Hiv 감염 및 aids에 대한 리보자임 유전자 치료(ribozyme gene therapy for hiv infection and aids)
|
|
US5837501A
(en)
|
1993-07-09 |
1998-11-17 |
Akzo Nobel N.V. |
Nucleic acid quantitation by co-amplification of target with multiple internal controls
|
|
US5804566A
(en)
|
1993-08-26 |
1998-09-08 |
The Regents Of The University Of California |
Methods and devices for immunizing a host through administration of naked polynucleotides with encode allergenic peptides
|
|
US5679647A
(en)
|
1993-08-26 |
1997-10-21 |
The Regents Of The University Of California |
Methods and devices for immunizing a host against tumor-associated antigens through administration of naked polynucleotides which encode tumor-associated antigenic peptides
|
|
CN1135181A
(zh)
|
1993-09-14 |
1996-11-06 |
Cytel有限公司 |
使用泛dr结合肽改变免疫应答
|
|
US5681697A
(en)
|
1993-12-08 |
1997-10-28 |
Chiron Corporation |
Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor
|
|
CH686982A5
(fr)
|
1993-12-16 |
1996-08-15 |
Maurice Stroun |
Méthode pour le diagnostic de cancers.
|
|
US5739118A
(en)
|
1994-04-01 |
1998-04-14 |
Apollon, Inc. |
Compositions and methods for delivery of genetic material
|
|
ES2210306T3
(es)
|
1994-07-20 |
2004-07-01 |
The General Hospital Corporation |
Sistemas de trampa para interacciones, para detectar interacciones de proteinas.
|
|
US5580731A
(en)
|
1994-08-25 |
1996-12-03 |
Chiron Corporation |
N-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewith
|
|
US5597909A
(en)
|
1994-08-25 |
1997-01-28 |
Chiron Corporation |
Polynucleotide reagents containing modified deoxyribose moieties, and associated methods of synthesis and use
|
|
US5681702A
(en)
|
1994-08-30 |
1997-10-28 |
Chiron Corporation |
Reduction of nonspecific hybridization by using novel base-pairing schemes
|
|
US5919652A
(en)
|
1994-11-09 |
1999-07-06 |
The Regents Of The University Of California |
Nucleic acid molecules comprising the prostate specific antigen (PSA) promoter and uses thereof
|
|
US5736524A
(en)
|
1994-11-14 |
1998-04-07 |
Merck & Co.,. Inc. |
Polynucleotide tuberculosis vaccine
|
|
US5962428A
(en)
|
1995-03-30 |
1999-10-05 |
Apollon, Inc. |
Compositions and methods for delivery of genetic material
|
|
EP0830459B1
(en)
|
1995-04-11 |
2007-01-24 |
The General Hospital Corporation |
Reverse two-hybrid systems
|
|
US5922687A
(en)
|
1995-05-04 |
1999-07-13 |
Board Of Trustees Of The Leland Stanford Junior University |
Intracellular delivery of nucleic acids using pressure
|
|
CU22559A1
(es)
|
1996-01-17 |
1999-05-03 |
Ct Ingenieria Genetica Biotech |
Sistema de expresión de antígenos heterologos en e. coli como proteínas de fusión
|
|
EP0914142B9
(en)
|
1996-03-11 |
2012-01-04 |
Epimmune Inc. |
Peptides with increased binding affinity for at least three hla-a3-like molecules
|
|
CA2252886C
(en)
|
1996-04-26 |
2008-02-12 |
Massachusetts Institute Of Technology |
Three-hybrid screening assay
|
|
JP2000516090A
(ja)
|
1996-07-26 |
2000-12-05 |
スローン―ケッタリング インスティチュート フォー キャンサー リサーチ |
遺伝子的免疫化のための方法と試薬
|
|
US5925523A
(en)
|
1996-08-23 |
1999-07-20 |
President & Fellows Of Harvard College |
Intraction trap assay, reagents and uses thereof
|
|
US6365797B1
(en)
|
1997-10-15 |
2002-04-02 |
The Regents Of The University Of California |
Mice models of human prostate cancer progression
|
|
EP0953039B1
(en)
|
1996-10-15 |
2007-08-29 |
The Regents Of The University Of California |
Animal models of human prostate cancer progression
|
|
US5846722A
(en)
|
1996-10-16 |
1998-12-08 |
Terrapin Technologies, Inc. |
System to detect small molecule/peptide interaction
|
|
US5840501A
(en)
|
1996-10-25 |
1998-11-24 |
Bayer Corporation |
Determination of cPSA
|
|
EP1972194A1
(en)
|
1996-12-03 |
2008-09-24 |
Amgen Fremont Inc. |
Transgenic mammals having human ig loci including plural vh and vk regions and antibodies produced therefrom
|
|
CA2407449A1
(en)
*
|
2000-04-27 |
2001-11-01 |
Smithkline Beecham Corporation |
Novel compounds
|
|
US6863892B2
(en)
*
|
2000-08-22 |
2005-03-08 |
Agensys, Inc. |
Nucleic acid and corresponding protein named 158P1D7 useful in the treatment and detection of bladder and other cancers
|
|
ATE549347T1
(de)
*
|
2000-09-08 |
2012-03-15 |
Schering Corp |
Gene von säugetiere, und damit verbundene reagentien, methoden
|
|
WO2002026826A2
(en)
*
|
2000-09-27 |
2002-04-04 |
Curagen Corporation |
Proteins and nucleic acids encoding same
|
|
EP1425302A2
(en)
*
|
2001-01-24 |
2004-06-09 |
Protein Design Labs |
Methods of diagnosis of breast cancer, compositions and methods of screening for modulators of breast cancer
|
|
WO2003102155A2
(en)
*
|
2002-06-03 |
2003-12-11 |
Curagen Corporation |
Therapeutic polypeptides, nucleic acids encoding same, and methods of use
|
|
US9701019B2
(en)
|
2011-09-15 |
2017-07-11 |
Convergent Information Technologies Gmbh |
System and method for the automatic generation of robot programs
|