JP2011182801A5 - - Google Patents

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Publication number
JP2011182801A5
JP2011182801A5 JP2011131898A JP2011131898A JP2011182801A5 JP 2011182801 A5 JP2011182801 A5 JP 2011182801A5 JP 2011131898 A JP2011131898 A JP 2011131898A JP 2011131898 A JP2011131898 A JP 2011131898A JP 2011182801 A5 JP2011182801 A5 JP 2011182801A5
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JP
Japan
Prior art keywords
gene segment
humanized
locus
gene
nucleic acid
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JP2011131898A
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English (en)
Japanese (ja)
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JP2011182801A (ja
JP6017763B2 (ja
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Publication of JP2011182801A5 publication Critical patent/JP2011182801A5/ja
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Publication of JP6017763B2 publication Critical patent/JP6017763B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP2011131898A 2003-07-15 2011-06-14 ヒト化免疫グロブリン遺伝子座 Expired - Lifetime JP6017763B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48773303P 2003-07-15 2003-07-15
US60/487,733 2003-07-15

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2006520411A Division JP2007537704A (ja) 2003-07-15 2004-07-15 ヒト化免疫グロブリン遺伝子座

Publications (3)

Publication Number Publication Date
JP2011182801A JP2011182801A (ja) 2011-09-22
JP2011182801A5 true JP2011182801A5 (enExample) 2012-07-19
JP6017763B2 JP6017763B2 (ja) 2016-11-02

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ID=34079388

Family Applications (2)

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JP2006520411A Withdrawn JP2007537704A (ja) 2003-07-15 2004-07-15 ヒト化免疫グロブリン遺伝子座
JP2011131898A Expired - Lifetime JP6017763B2 (ja) 2003-07-15 2011-06-14 ヒト化免疫グロブリン遺伝子座

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JP2006520411A Withdrawn JP2007537704A (ja) 2003-07-15 2004-07-15 ヒト化免疫グロブリン遺伝子座

Country Status (10)

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US (4) US7585668B2 (enExample)
EP (1) EP1644417B1 (enExample)
JP (2) JP2007537704A (enExample)
CN (2) CN1852925A (enExample)
AU (1) AU2004257292A1 (enExample)
CA (1) CA2532117C (enExample)
ES (1) ES2473596T3 (enExample)
IL (1) IL172885A0 (enExample)
MX (1) MXPA06000562A (enExample)
WO (1) WO2005007696A2 (enExample)

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EP3348140B1 (en) 2012-03-16 2020-12-30 Regeneron Pharmaceuticals, Inc. Histidine engineered light chain antibodies and genetically modified rodents for generating the same
RU2018128915A (ru) 2012-03-16 2019-02-18 Регенерон Фармасьютикалз, Инк. ОТЛИЧНЫЕ ОТ ЧЕЛОВЕКА ЖИВОТНЫЕ, ЭКСПРЕССИРУЮЩИЕ ЧУВСТВИТЕЛЬНЫЕ К рН ПОСЛЕДОВАТЕЛЬНОСТИ ИММУНОГЛОБУЛИНОВ
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KR102159163B1 (ko) 2012-08-03 2020-09-23 에스에이비, 엘엘씨 유전자삽입 동물에서 인간 항체의 제조를 위한 복합 염색체 조작
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