JP2011137020A5 - - Google Patents
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- Publication number
- JP2011137020A5 JP2011137020A5 JP2011033064A JP2011033064A JP2011137020A5 JP 2011137020 A5 JP2011137020 A5 JP 2011137020A5 JP 2011033064 A JP2011033064 A JP 2011033064A JP 2011033064 A JP2011033064 A JP 2011033064A JP 2011137020 A5 JP2011137020 A5 JP 2011137020A5
- Authority
- JP
- Japan
- Prior art keywords
- oral dosage
- dosage form
- sustained release
- oxycodone
- release oral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000006186 oral dosage form Substances 0.000 claims 21
- 238000013268 sustained release Methods 0.000 claims 18
- 239000012730 sustained-release form Substances 0.000 claims 18
- BRUQQQPBMZOVGD-XFKAJCMBSA-N Oxycodone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(OC)C2=C5[C@@]13CCN4C BRUQQQPBMZOVGD-XFKAJCMBSA-N 0.000 claims 15
- 229960002085 oxycodone Drugs 0.000 claims 15
- UZHSEJADLWPNLE-GRGSLBFTSA-N naloxone Chemical compound O=C([C@@H]1O2)CC[C@@]3(O)[C@H]4CC5=CC=C(O)C2=C5[C@@]13CCN4CC=C UZHSEJADLWPNLE-GRGSLBFTSA-N 0.000 claims 13
- 229960004127 naloxone Drugs 0.000 claims 13
- 150000003839 salts Chemical class 0.000 claims 9
- BQJCRHHNABKAKU-KBQPJGBKSA-N morphine Chemical compound O([C@H]1[C@H](C=C[C@H]23)O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O BQJCRHHNABKAKU-KBQPJGBKSA-N 0.000 claims 8
- 239000012458 free base Substances 0.000 claims 7
- 208000005793 Restless legs syndrome Diseases 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 5
- 229960005181 morphine Drugs 0.000 claims 4
- USSIQXCVUWKGNF-UHFFFAOYSA-N 6-(dimethylamino)-4,4-diphenylheptan-3-one Chemical compound C=1C=CC=CC=1C(CC(C)N(C)C)(C(=O)CC)C1=CC=CC=C1 USSIQXCVUWKGNF-UHFFFAOYSA-N 0.000 claims 3
- WJBLNOPPDWQMCH-MBPVOVBZSA-N Nalmefene Chemical compound N1([C@@H]2CC3=CC=C(C=4O[C@@H]5[C@](C3=4)([C@]2(CCC5=C)O)CC1)O)CC1CC1 WJBLNOPPDWQMCH-MBPVOVBZSA-N 0.000 claims 3
- UQCNKQCJZOAFTQ-ISWURRPUSA-N Oxymorphone Chemical compound O([C@H]1C(CC[C@]23O)=O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O UQCNKQCJZOAFTQ-ISWURRPUSA-N 0.000 claims 3
- XYYVYLMBEZUESM-UHFFFAOYSA-N dihydrocodeine Natural products C1C(N(CCC234)C)C2C=CC(=O)C3OC2=C4C1=CC=C2OC XYYVYLMBEZUESM-UHFFFAOYSA-N 0.000 claims 3
- 229960002428 fentanyl Drugs 0.000 claims 3
- PJMPHNIQZUBGLI-UHFFFAOYSA-N fentanyl Chemical compound C=1C=CC=CC=1N(C(=O)CC)C(CC1)CCN1CCC1=CC=CC=C1 PJMPHNIQZUBGLI-UHFFFAOYSA-N 0.000 claims 3
- LLPOLZWFYMWNKH-CMKMFDCUSA-N hydrocodone Chemical compound C([C@H]1[C@H](N(CC[C@@]112)C)C3)CC(=O)[C@@H]1OC1=C2C3=CC=C1OC LLPOLZWFYMWNKH-CMKMFDCUSA-N 0.000 claims 3
- 229960000240 hydrocodone Drugs 0.000 claims 3
- OROGSEYTTFOCAN-UHFFFAOYSA-N hydrocodone Natural products C1C(N(CCC234)C)C2C=CC(O)C3OC2=C4C1=CC=C2OC OROGSEYTTFOCAN-UHFFFAOYSA-N 0.000 claims 3
- WVLOADHCBXTIJK-YNHQPCIGSA-N hydromorphone Chemical compound O([C@H]1C(CC[C@H]23)=O)C4=C5[C@@]12CCN(C)[C@@H]3CC5=CC=C4O WVLOADHCBXTIJK-YNHQPCIGSA-N 0.000 claims 3
- 229960001410 hydromorphone Drugs 0.000 claims 3
- 229960001797 methadone Drugs 0.000 claims 3
- 229960005297 nalmefene Drugs 0.000 claims 3
- 229960003086 naltrexone Drugs 0.000 claims 3
- DQCKKXVULJGBQN-XFWGSAIBSA-N naltrexone Chemical compound N1([C@@H]2CC3=CC=C(C=4O[C@@H]5[C@](C3=4)([C@]2(CCC5=O)O)CC1)O)CC1CC1 DQCKKXVULJGBQN-XFWGSAIBSA-N 0.000 claims 3
- 239000003402 opiate agonist Substances 0.000 claims 3
- 239000003401 opiate antagonist Substances 0.000 claims 3
- 229960005118 oxymorphone Drugs 0.000 claims 3
- GGCSSNBKKAUURC-UHFFFAOYSA-N sufentanil Chemical compound C1CN(CCC=2SC=CC=2)CCC1(COC)N(C(=O)CC)C1=CC=CC=C1 GGCSSNBKKAUURC-UHFFFAOYSA-N 0.000 claims 3
- 229960004739 sufentanil Drugs 0.000 claims 3
- LLPOLZWFYMWNKH-UHFFFAOYSA-N trans-dihydrocodeinone Natural products C1C(N(CCC234)C)C2CCC(=O)C3OC2=C4C1=CC=C2OC LLPOLZWFYMWNKH-UHFFFAOYSA-N 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04013469.4 | 2004-06-08 | ||
| EP04013469A EP1604667A1 (en) | 2004-06-08 | 2004-06-08 | Opioids for the treatment of the restless leg syndrome |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007526247A Division JP2008501742A (ja) | 2004-06-08 | 2005-06-01 | 下肢静止不能症候群の治療用オピオイド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011137020A JP2011137020A (ja) | 2011-07-14 |
| JP2011137020A5 true JP2011137020A5 (OSRAM) | 2012-02-16 |
| JP5774865B2 JP5774865B2 (ja) | 2015-09-09 |
Family
ID=34925286
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007526247A Withdrawn JP2008501742A (ja) | 2004-06-08 | 2005-06-01 | 下肢静止不能症候群の治療用オピオイド |
| JP2011033064A Expired - Fee Related JP5774865B2 (ja) | 2004-06-08 | 2011-02-18 | 下肢静止不能症候群の治療用オピオイド |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007526247A Withdrawn JP2008501742A (ja) | 2004-06-08 | 2005-06-01 | 下肢静止不能症候群の治療用オピオイド |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US20070185147A1 (OSRAM) |
| EP (3) | EP1604667A1 (OSRAM) |
| JP (2) | JP2008501742A (OSRAM) |
| KR (2) | KR20070037485A (OSRAM) |
| CN (2) | CN103394090A (OSRAM) |
| AT (1) | ATE486603T1 (OSRAM) |
| AU (1) | AU2005251445C1 (OSRAM) |
| BR (1) | BRPI0511300A (OSRAM) |
| CA (1) | CA2569742C (OSRAM) |
| CY (1) | CY1111512T1 (OSRAM) |
| DE (1) | DE602005024571D1 (OSRAM) |
| DK (1) | DK1781291T3 (OSRAM) |
| ES (1) | ES2355247T3 (OSRAM) |
| HR (1) | HRP20110049T2 (OSRAM) |
| IL (1) | IL179896A (OSRAM) |
| ME (1) | ME01238B (OSRAM) |
| MX (1) | MXPA06014391A (OSRAM) |
| NO (1) | NO337890B1 (OSRAM) |
| NZ (1) | NZ552430A (OSRAM) |
| PL (1) | PL1781291T3 (OSRAM) |
| PT (1) | PT1781291E (OSRAM) |
| RS (1) | RS51573B (OSRAM) |
| SI (1) | SI1781291T1 (OSRAM) |
| WO (1) | WO2005120506A1 (OSRAM) |
| ZA (1) | ZA200610477B (OSRAM) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU773642C (en) | 1997-12-22 | 2006-04-06 | Mundipharma Pty Limited | Opioid agonist/antagonist combinations |
| US6375957B1 (en) | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
| CN1525851A (zh) | 2001-05-11 | 2004-09-01 | ������ҩ������˾ | 抗滥用阿片样物质控释剂型 |
| EP2316428A1 (en) | 2002-04-05 | 2011-05-04 | Euro-Celtique S.A. | Matrix for sustained, invariant and independent release of active compounds |
| EP1604666A1 (en) | 2004-06-08 | 2005-12-14 | Euro-Celtique S.A. | Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD) |
| EP1702558A1 (en) | 2005-02-28 | 2006-09-20 | Euro-Celtique S.A. | Method and device for the assessment of bowel function |
| US8445018B2 (en) | 2006-09-15 | 2013-05-21 | Cima Labs Inc. | Abuse resistant drug formulation |
| US8632805B2 (en) * | 2008-06-20 | 2014-01-21 | Mutual Pharmaceutical Company, Inc. | Controlled-release formulations, method of manufacture, and use thereof |
| US7794750B2 (en) * | 2008-06-20 | 2010-09-14 | Mutual Pharmaceutical Company, Inc. | Controlled-release formulations, method of manufacture, and use thereof |
| KR20140141727A (ko) | 2009-03-10 | 2014-12-10 | 유로-셀티큐 에스.에이. | 옥시코돈 및 날록손을 포함하는 즉시 방출 제약 조성물 |
| KR101858797B1 (ko) | 2010-05-10 | 2018-05-16 | 유로-셀티큐 에스.에이. | 히드로모르폰 및 날록손을 포함하는 제약 조성물 |
| WO2011141489A1 (en) | 2010-05-10 | 2011-11-17 | Euro-Celtique S.A. | Manufacturing of active-free granules and tablets comprising the same |
| NZ603170A (en) | 2010-05-10 | 2015-04-24 | Euro Celtique Sa | Combination of active loaded granules with additional actives |
| US20180264013A1 (en) * | 2010-07-08 | 2018-09-20 | Wellesley Pharmaceuticals, Llc | Composition and methods for treating sleep disorders |
| MX355644B (es) * | 2010-08-13 | 2018-04-26 | Euro Celtique S A Star | Uso de aglutinantes para fabricar formulaciones estables al almacenamiento. |
| WO2015011189A1 (en) | 2013-07-23 | 2015-01-29 | Euro-Celtique S.A. | A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation |
| UA116405C2 (uk) | 2013-11-13 | 2018-03-12 | Євро-Селтік С.А. | Гідроморфон та налоксон для лікування болю та синдрому опіоїдної дисфункції кишечнику |
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| NL6714885A (OSRAM) | 1967-11-02 | 1969-05-06 | ||
| US3541006A (en) | 1968-07-03 | 1970-11-17 | Amicon Corp | Ultrafiltration process |
| US3541005A (en) | 1969-02-05 | 1970-11-17 | Amicon Corp | Continuous ultrafiltration of macromolecular solutions |
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| US3916889A (en) | 1973-09-28 | 1975-11-04 | Sandoz Ag | Patient ventilator apparatus |
| GB1478759A (en) | 1974-11-18 | 1977-07-06 | Alza Corp | Process for forming outlet passageways in pills using a laser |
| US3966040A (en) * | 1975-03-05 | 1976-06-29 | Hazelwood John E | Combined vibratory feeder drive unit, vibratory feeder bowl, and parts separator |
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| US4063064A (en) | 1976-02-23 | 1977-12-13 | Coherent Radiation | Apparatus for tracking moving workpiece by a laser beam |
| US4285987A (en) | 1978-10-23 | 1981-08-25 | Alza Corporation | Process for manufacturing device with dispersion zone |
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-
2004
- 2004-06-08 EP EP04013469A patent/EP1604667A1/en not_active Withdrawn
-
2005
- 2005-06-01 HR HR20110049A patent/HRP20110049T2/hr unknown
- 2005-06-01 EP EP10175878A patent/EP2255808A3/en not_active Withdrawn
- 2005-06-01 AT AT05754710T patent/ATE486603T1/de active
- 2005-06-01 KR KR1020077000489A patent/KR20070037485A/ko not_active Ceased
- 2005-06-01 KR KR1020097016692A patent/KR101200869B1/ko not_active Expired - Lifetime
- 2005-06-01 DK DK05754710.1T patent/DK1781291T3/da active
- 2005-06-01 RS RS20110030A patent/RS51573B/sr unknown
- 2005-06-01 BR BRPI0511300-8A patent/BRPI0511300A/pt not_active Application Discontinuation
- 2005-06-01 WO PCT/EP2005/005888 patent/WO2005120506A1/en not_active Ceased
- 2005-06-01 CA CA2569742A patent/CA2569742C/en not_active Expired - Fee Related
- 2005-06-01 PT PT05754710T patent/PT1781291E/pt unknown
- 2005-06-01 EP EP05754710A patent/EP1781291B9/en not_active Expired - Lifetime
- 2005-06-01 PL PL05754710T patent/PL1781291T3/pl unknown
- 2005-06-01 DE DE602005024571T patent/DE602005024571D1/de not_active Expired - Lifetime
- 2005-06-01 US US11/570,222 patent/US20070185147A1/en not_active Abandoned
- 2005-06-01 JP JP2007526247A patent/JP2008501742A/ja not_active Withdrawn
- 2005-06-01 ME MEP-2011-18A patent/ME01238B/me unknown
- 2005-06-01 CN CN2013102699069A patent/CN103394090A/zh active Pending
- 2005-06-01 SI SI200531198T patent/SI1781291T1/sl unknown
- 2005-06-01 NZ NZ552430A patent/NZ552430A/en not_active IP Right Cessation
- 2005-06-01 MX MXPA06014391A patent/MXPA06014391A/es active IP Right Grant
- 2005-06-01 CN CNA2005800231113A patent/CN1984659A/zh active Pending
- 2005-06-01 AU AU2005251445A patent/AU2005251445C1/en not_active Expired
- 2005-06-01 ES ES05754710T patent/ES2355247T3/es not_active Expired - Lifetime
-
2006
- 2006-12-06 IL IL179896A patent/IL179896A/en active IP Right Grant
- 2006-12-14 ZA ZA200610477A patent/ZA200610477B/en unknown
-
2007
- 2007-01-08 NO NO20070113A patent/NO337890B1/no not_active IP Right Cessation
-
2011
- 2011-02-03 CY CY20111100121T patent/CY1111512T1/el unknown
- 2011-02-18 JP JP2011033064A patent/JP5774865B2/ja not_active Expired - Fee Related
- 2011-12-21 US US13/333,719 patent/US20120172387A1/en not_active Abandoned
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