JP2011088897A5 - - Google Patents
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- Publication number
- JP2011088897A5 JP2011088897A5 JP2010253233A JP2010253233A JP2011088897A5 JP 2011088897 A5 JP2011088897 A5 JP 2011088897A5 JP 2010253233 A JP2010253233 A JP 2010253233A JP 2010253233 A JP2010253233 A JP 2010253233A JP 2011088897 A5 JP2011088897 A5 JP 2011088897A5
- Authority
- JP
- Japan
- Prior art keywords
- apo
- ligand
- formulation
- metal ions
- divalent metal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14134299P | 1999-06-28 | 1999-06-28 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001506824A Division JP5118796B2 (ja) | 1999-06-28 | 2000-06-26 | 二価の金属イオンを利用したＡｐｏ−２リガンドの製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011088897A JP2011088897A (ja) | 2011-05-06 |
| JP2011088897A5 true JP2011088897A5 (enExample) | 2012-02-02 |
Family
ID=22495287
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001506824A Expired - Lifetime JP5118796B2 (ja) | 1999-06-28 | 2000-06-26 | 二価の金属イオンを利用したＡｐｏ−２リガンドの製造方法 |
| JP2010253233A Pending JP2011088897A (ja) | 1999-06-28 | 2010-11-11 | 二価の金属イオンを利用したＡｐｏ−２リガンドの製造方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001506824A Expired - Lifetime JP5118796B2 (ja) | 1999-06-28 | 2000-06-26 | 二価の金属イオンを利用したＡｐｏ−２リガンドの製造方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US7855066B1 (enExample) |
| EP (3) | EP2311956A1 (enExample) |
| JP (2) | JP5118796B2 (enExample) |
| KR (1) | KR100674528B1 (enExample) |
| CN (2) | CN101633692A (enExample) |
| AU (3) | AU6338200A (enExample) |
| CA (1) | CA2377585A1 (enExample) |
| ES (1) | ES2392392T3 (enExample) |
| IL (2) | IL147029A0 (enExample) |
| MX (1) | MXPA01013236A (enExample) |
| NZ (2) | NZ537920A (enExample) |
| WO (1) | WO2001000832A1 (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020106728A1 (en) * | 2000-06-20 | 2002-08-08 | Genentech, Inc. | NS4 nucleic acids and polypeptides and methods of use for the treatment of body weight disorders |
| EP1867719A3 (en) * | 1999-06-02 | 2008-03-19 | Genentech, Inc. | Methods and compositions for inhibiting neoplastic cell growth |
| ES2392392T3 (es) * | 1999-06-28 | 2012-12-10 | Genentech, Inc. | Métodos para producir ligando Apo-2 utilizando iones metálicos divalentes |
| CA2461292A1 (en) * | 2001-10-02 | 2003-04-10 | Genentech, Inc. | Apo-2 ligand variants and uses thereof |
| DE60237841D1 (de) | 2001-11-13 | 2010-11-11 | Genentech Inc | Zusammensetzungen basierend auf APO2-Ligand/ TRAIL und ihre Verwendung |
| US7842668B1 (en) | 2001-11-13 | 2010-11-30 | Genentech, Inc. | Apo-2 ligand/trail formulations |
| US7741285B2 (en) * | 2001-11-13 | 2010-06-22 | Genentech, Inc. | APO-2 ligand/trail formulations |
| AU2007200478A1 (en) * | 2001-11-13 | 2007-02-22 | Genentech, Inc. | APO2 ligand/trail formulations |
| JP4574350B2 (ja) * | 2002-06-24 | 2010-11-04 | ジェネンテック， インコーポレイテッド | Ａｐｏ−２リガンド／ｔｒａｉｌ変異体とその使用法 |
| GB0328261D0 (en) * | 2003-12-05 | 2004-01-07 | Univ Groningen | Improved cytokine design |
| ZA200606913B (en) | 2004-03-11 | 2008-03-26 | Genentech Inc | Process for producing polypeptides |
| CA2575152A1 (en) | 2004-08-06 | 2006-02-16 | Genentech, Inc. | Method for predicting sensitivity of mammalian cells to apo2l/trail comprising deletion of biomarker expression |
| RU2410438C2 (ru) | 2004-08-06 | 2011-01-27 | Дженентек, Инк. | Анализы и способы, использующие биомаркеры |
| JO3000B1 (ar) | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| US8029783B2 (en) | 2005-02-02 | 2011-10-04 | Genentech, Inc. | DR5 antibodies and articles of manufacture containing same |
| RU2409817C2 (ru) | 2005-08-16 | 2011-01-20 | Дженентек, Инк. | Анализы и способы применения биомаркеров |
| GB0524316D0 (en) * | 2005-11-29 | 2006-01-04 | Medical Res Council | Tumour necrosis factor-related apoptosis-inducing ligands (TRAILs) |
| WO2010146059A2 (en) | 2009-06-16 | 2010-12-23 | F. Hoffmann-La Roche Ag | Biomarkers for igf-1r inhibitor therapy |
| WO2012151317A1 (en) | 2011-05-03 | 2012-11-08 | Genentech, Inc. | Vascular disruption agents and uses thereof |
| CN102775491A (zh) * | 2011-05-09 | 2012-11-14 | 中国人民解放军第二军医大学 | 单链化的人凋亡素2配体三聚体蛋白质的制法和用途 |
| CN102443055B (zh) * | 2011-10-26 | 2017-07-28 | 浙江海正药业股份有限公司 | 一种重组人肿瘤坏死因子相关凋亡诱导配体的纯化工艺 |
| JP6355425B2 (ja) * | 2014-05-20 | 2018-07-11 | キヤノン株式会社 | システムおよびその制御方法 |
| US11279768B1 (en) | 2015-04-03 | 2022-03-22 | Precision Biologics, Inc. | Anti-cancer antibodies, combination therapies, and uses thereof |
| US10906951B2 (en) * | 2015-07-29 | 2021-02-02 | Onk Therapeutics Limited | Modified natural killer cells and natural killer cell lines having increased cytotoxicity |
| WO2017161173A1 (en) * | 2016-03-16 | 2017-09-21 | Merrimack Pharmaceuticals, Inc. | Engineered trail for cancer therapy |
| CN111320384A (zh) * | 2019-04-04 | 2020-06-23 | 株式会社小原 | 光学玻璃的制造方法 |
| JP7429622B2 (ja) * | 2020-08-26 | 2024-02-08 | 株式会社オハラ | 光学ガラスの製造方法 |
| CN115980241B (zh) * | 2023-02-11 | 2025-01-07 | 烟台新特路新材料科技有限公司 | 一种硫代酯类抗氧化剂含量的检测方法 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
| IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| US4713339A (en) | 1983-01-19 | 1987-12-15 | Genentech, Inc. | Polycistronic expression vector construction |
| AU2353384A (en) | 1983-01-19 | 1984-07-26 | Genentech Inc. | Amplification in eukaryotic host cells |
| DD266710A3 (de) | 1983-06-06 | 1989-04-12 | Ve Forschungszentrum Biotechnologie | Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase |
| HUT35524A (en) | 1983-08-02 | 1985-07-29 | Hoechst Ag | Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance |
| DE3779221D1 (de) | 1986-08-19 | 1992-06-25 | Genentech Inc | Einrichtung und dispersion zum intrapulmonalen eingeben von polypeptidwuchsstoffen und -zytokinen. |
| ATE105585T1 (de) | 1987-12-21 | 1994-05-15 | Univ Toledo | Transformation von keimenden pflanzensamen mit hilfe von agrobacterium. |
| US6063763A (en) * | 1989-04-28 | 2000-05-16 | Schering Aktiengesellschaft | Protease-resistant thrombomodulin analogs |
| DK168302B1 (da) | 1989-06-29 | 1994-03-07 | Danisco | Fremgangsmåde til indføring af molekyler, især genetisk materiale i planteceller |
| DE10399023I2 (de) | 1989-09-12 | 2006-11-23 | Ahp Mfg B V | TFN-bindende Proteine |
| CA2087267A1 (en) | 1990-08-17 | 1992-02-18 | Steven H. Bass | Metal ion mediated receptor binding of polypeptide hormones |
| US5206161A (en) | 1991-02-01 | 1993-04-27 | Genentech, Inc. | Human plasma carboxypeptidase B |
| AU1757092A (en) | 1991-03-28 | 1992-11-02 | Genentech Inc. | Stable growth hormone metal ion formulations |
| US6387650B1 (en) * | 1995-06-07 | 2002-05-14 | Biocontrol Systems, Inc. | Method and composition for detecting bacterial contamination in food products |
| ES2253753T3 (es) * | 1995-06-29 | 2006-06-01 | Immunex Corporation | Citocina que induce apoptosis. |
| DE19547933A1 (de) * | 1995-12-22 | 1997-06-26 | Boehringer Mannheim Gmbh | Multimere Formen von IL-16, Verfahren zu ihrer Herstellung und Verwendung |
| US6030945A (en) * | 1996-01-09 | 2000-02-29 | Genentech, Inc. | Apo-2 ligand |
| AU5711196A (en) | 1996-03-14 | 1997-10-01 | Human Genome Sciences, Inc. | Apoptosis inducing molecule i |
| JP2000515727A (ja) | 1996-06-07 | 2000-11-28 | アムジエン・インコーポレーテツド | 腫瘍壊死因子関連ポリペプチド |
| BR9713248A (pt) | 1996-10-03 | 2000-01-18 | Biotherapies Inc | Sequência de nucleotìdeos e de proteìnas de mamastatina e processos de uso |
| EP0939804B2 (en) | 1996-10-25 | 2011-06-15 | Human Genome Sciences, Inc. | NEUTROKINE alpha |
| EP2003203A1 (en) | 1996-12-23 | 2008-12-17 | Immunex Corporation | Ligand for receptor activator of nf-kappa b, ligand is member of TNF superfamily |
| ATE363533T1 (de) | 1997-04-16 | 2007-06-15 | Amgen Inc | Osteoprotegerin bindende proteine und rezeptoren |
| ATE516354T1 (de) | 1997-05-15 | 2011-07-15 | Genentech Inc | Apo-2-rezeptor |
| ES2331900T3 (es) | 1997-08-26 | 2010-01-19 | Genentech, Inc. | Receptor rtd. |
| ATE411385T1 (de) * | 1998-01-15 | 2008-10-15 | Genentech Inc | Apo-2 ligand |
| SE9802454D0 (sv) | 1998-07-08 | 1998-07-08 | Pharmacia & Upjohn Ab | Production of peptides |
| ES2392392T3 (es) * | 1999-06-28 | 2012-12-10 | Genentech, Inc. | Métodos para producir ligando Apo-2 utilizando iones metálicos divalentes |
| WO2001018041A2 (en) | 1999-09-10 | 2001-03-15 | Eli Lilly And Company | Flint proteins and formulations thereof |
| AU6891800A (en) | 1999-09-10 | 2001-04-10 | Eli Lilly And Company | Flint analog compounds and formulations thereof |
| CA2461292A1 (en) * | 2001-10-02 | 2003-04-10 | Genentech, Inc. | Apo-2 ligand variants and uses thereof |
| DE60237841D1 (de) * | 2001-11-13 | 2010-11-11 | Genentech Inc | Zusammensetzungen basierend auf APO2-Ligand/ TRAIL und ihre Verwendung |
| CN100500841C (zh) * | 2005-10-10 | 2009-06-17 | 华东理工大学 | 一种表达可溶性trail蛋白的方法 |
-
2000
- 2000-06-26 ES ES00950255T patent/ES2392392T3/es not_active Expired - Lifetime
- 2000-06-26 CN CN200910145880A patent/CN101633692A/zh active Pending
- 2000-06-26 CA CA002377585A patent/CA2377585A1/en not_active Abandoned
- 2000-06-26 EP EP10010654A patent/EP2311956A1/en not_active Withdrawn
- 2000-06-26 NZ NZ537920A patent/NZ537920A/en not_active IP Right Cessation
- 2000-06-26 AU AU63382/00A patent/AU6338200A/en not_active Abandoned
- 2000-06-26 MX MXPA01013236A patent/MXPA01013236A/es active IP Right Grant
- 2000-06-26 EP EP00950255A patent/EP1194555B1/en not_active Expired - Lifetime
- 2000-06-26 NZ NZ515990A patent/NZ515990A/en not_active IP Right Cessation
- 2000-06-26 KR KR1020017016748A patent/KR100674528B1/ko not_active Expired - Lifetime
- 2000-06-26 WO PCT/US2000/017579 patent/WO2001000832A1/en not_active Ceased
- 2000-06-26 CN CNB008119589A patent/CN100526463C/zh not_active Expired - Lifetime
- 2000-06-26 JP JP2001506824A patent/JP5118796B2/ja not_active Expired - Lifetime
- 2000-06-26 EP EP10010653A patent/EP2339003A3/en not_active Withdrawn
- 2000-06-26 IL IL14702900A patent/IL147029A0/xx unknown
-
2001
- 2001-12-11 IL IL147029A patent/IL147029A/en active IP Right Grant
-
2005
- 2005-09-16 AU AU2005211561A patent/AU2005211561B2/en not_active Expired
-
2006
- 2006-09-28 US US11/528,948 patent/US7855066B1/en not_active Expired - Fee Related
- 2006-11-22 US US11/603,584 patent/US20070161564A1/en not_active Abandoned
-
2008
- 2008-11-21 AU AU2008249162A patent/AU2008249162A1/en not_active Abandoned
-
2010
- 2010-11-11 JP JP2010253233A patent/JP2011088897A/ja active Pending
- 2010-12-10 US US12/928,422 patent/US20120077740A1/en not_active Abandoned
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