JP2011050389A5 - - Google Patents
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- JP2011050389A5 JP2011050389A5 JP2010228397A JP2010228397A JP2011050389A5 JP 2011050389 A5 JP2011050389 A5 JP 2011050389A5 JP 2010228397 A JP2010228397 A JP 2010228397A JP 2010228397 A JP2010228397 A JP 2010228397A JP 2011050389 A5 JP2011050389 A5 JP 2011050389A5
- Authority
- JP
- Japan
- Prior art keywords
- mammal
- test sample
- polypeptide
- sample
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 238000000034 method Methods 0.000 claims 21
- 239000000523 sample Substances 0.000 claims 17
- 241000124008 Mammalia Species 0.000 claims 10
- 210000004027 cell Anatomy 0.000 claims 10
- 230000014509 gene expression Effects 0.000 claims 9
- 229920001184 polypeptide Polymers 0.000 claims 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims 8
- 102000004196 processed proteins & peptides Human genes 0.000 claims 8
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- 210000003719 b-lymphocyte Anatomy 0.000 claims 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 230000028993 immune response Effects 0.000 claims 6
- 230000002757 inflammatory effect Effects 0.000 claims 6
- 201000010099 disease Diseases 0.000 claims 5
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 claims 4
- 239000013068 control sample Substances 0.000 claims 4
- 208000026278 immune system disease Diseases 0.000 claims 4
- 230000001404 mediated effect Effects 0.000 claims 4
- 206010002556 Ankylosing Spondylitis Diseases 0.000 claims 2
- 208000011691 Burkitt lymphomas Diseases 0.000 claims 2
- 208000035186 Hemolytic Autoimmune Anemia Diseases 0.000 claims 2
- 206010020751 Hypersensitivity Diseases 0.000 claims 2
- 208000007924 IgA Deficiency Diseases 0.000 claims 2
- 206010061598 Immunodeficiency Diseases 0.000 claims 2
- 208000029462 Immunodeficiency disease Diseases 0.000 claims 2
- 206010025323 Lymphomas Diseases 0.000 claims 2
- 206010039915 Selective IgA immunodeficiency Diseases 0.000 claims 2
- 208000028483 Selective IgM deficiency Diseases 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- 210000004404 adrenal cortex Anatomy 0.000 claims 2
- 208000026935 allergic disease Diseases 0.000 claims 2
- 239000000427 antigen Substances 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 201000000448 autoimmune hemolytic anemia Diseases 0.000 claims 2
- 230000007812 deficiency Effects 0.000 claims 2
- 201000003444 follicular lymphoma Diseases 0.000 claims 2
- 150000004676 glycans Chemical class 0.000 claims 2
- 238000009396 hybridization Methods 0.000 claims 2
- 230000009610 hypersensitivity Effects 0.000 claims 2
- 230000007813 immunodeficiency Effects 0.000 claims 2
- 201000007156 immunoglobulin alpha deficiency Diseases 0.000 claims 2
- 230000021633 leukocyte mediated immunity Effects 0.000 claims 2
- 206010028417 myasthenia gravis Diseases 0.000 claims 2
- 201000008383 nephritis Diseases 0.000 claims 2
- 229920001282 polysaccharide Polymers 0.000 claims 2
- 239000005017 polysaccharide Substances 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 2
- 208000029138 selective IgA deficiency disease Diseases 0.000 claims 2
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 2
- 230000001052 transient effect Effects 0.000 claims 2
- 241000972773 Aulopiformes Species 0.000 claims 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 229960000633 dextran sulfate Drugs 0.000 claims 1
- 208000035475 disorder Diseases 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 238000002493 microarray Methods 0.000 claims 1
- 235000019515 salmon Nutrition 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 239000001509 sodium citrate Substances 0.000 claims 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 1
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 claims 1
- 239000001488 sodium phosphate Substances 0.000 claims 1
- 229910000162 sodium phosphate Inorganic materials 0.000 claims 1
- 229940048086 sodium pyrophosphate Drugs 0.000 claims 1
- 235000019818 tetrasodium diphosphate Nutrition 0.000 claims 1
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 claims 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41139202P | 2002-09-16 | 2002-09-16 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004536566A Division JP2006515165A (ja) | 2002-09-16 | 2003-09-15 | 免疫関連疾患の治療のための新規組成物と方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011086366A Division JP2011172580A (ja) | 2002-09-16 | 2011-04-08 | 免疫関連疾患の治療のための新規組成物と方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011050389A JP2011050389A (ja) | 2011-03-17 |
| JP2011050389A5 true JP2011050389A5 (https=) | 2011-05-26 |
Family
ID=31994259
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004536566A Withdrawn JP2006515165A (ja) | 2002-09-16 | 2003-09-15 | 免疫関連疾患の治療のための新規組成物と方法 |
| JP2010228397A Pending JP2011050389A (ja) | 2002-09-16 | 2010-10-08 | 免疫関連疾患の治療のための新規組成物と方法 |
| JP2011086366A Withdrawn JP2011172580A (ja) | 2002-09-16 | 2011-04-08 | 免疫関連疾患の治療のための新規組成物と方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004536566A Withdrawn JP2006515165A (ja) | 2002-09-16 | 2003-09-15 | 免疫関連疾患の治療のための新規組成物と方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011086366A Withdrawn JP2011172580A (ja) | 2002-09-16 | 2011-04-08 | 免疫関連疾患の治療のための新規組成物と方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20070010434A1 (https=) |
| EP (2) | EP2444409A2 (https=) |
| JP (3) | JP2006515165A (https=) |
| AU (2) | AU2003291625B2 (https=) |
| CA (1) | CA2498274A1 (https=) |
| WO (1) | WO2004024097A2 (https=) |
Families Citing this family (38)
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| WO2004012755A1 (en) * | 2002-08-05 | 2004-02-12 | The Wistar Institute | Methods for regulating brca1-brca2-containing complex activity |
| AU2002950779A0 (en) * | 2002-08-15 | 2002-09-12 | The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland | A method of immunomodulation |
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| US20050186577A1 (en) | 2004-02-20 | 2005-08-25 | Yixin Wang | Breast cancer prognostics |
| US20050272067A1 (en) * | 2004-03-10 | 2005-12-08 | Macina Roberto A | Compositions, splice variants and methods relating to cancer specific genes and proteins |
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| RU2540013C2 (ru) | 2008-03-13 | 2015-01-27 | Биотест Аг | Средство для лечения заболевания |
| EP2260057B1 (en) | 2008-03-13 | 2016-11-23 | Biotest AG | Anti-CD4 antibody dosage regimen for treating autoimmune disease |
| EP2265643B1 (en) | 2008-03-13 | 2016-10-19 | Biotest AG | Dosing regimen for treating psoriasis and rheumatoid arthritis |
| US8540985B2 (en) | 2008-06-26 | 2013-09-24 | Orphazyme Aps | Use of Hsp70 as a regulator of enzymatic activity |
| US11693009B2 (en) | 2009-02-11 | 2023-07-04 | Cedars-Sinai Medical Center | Methods for detecting post-infectious irritable bowel syndrome |
| WO2010141999A1 (en) * | 2009-06-12 | 2010-12-16 | The University Of Queensland | Agents and methods for diagnosing and treating ankylosing spondylitis |
| GB0920944D0 (en) | 2009-11-30 | 2010-01-13 | Biotest Ag | Agents for treating disease |
| RU2013125923A (ru) | 2010-11-30 | 2015-01-10 | Орфазиме Апс | СПОСОБЫ УВЕЛИЧЕНИЯ ВНУТРИКЛЕТОЧНОЙ АКТИВНОСТИ Hsp70 |
| AU2013315981B2 (en) | 2012-09-17 | 2019-04-18 | Cedars-Sinai Medical Center | Diagnosis and treatment of motility disorders of the gut and bladder, and of fibromyalgia |
| RU2683781C2 (ru) | 2013-10-09 | 2019-04-02 | Седарс-Синаи Медикал Сентер | Диагностика и лечение синдрома раздраженного кишечника и воспалительного заболевания кишечника |
| CN105745224B (zh) | 2013-10-11 | 2019-11-05 | 牛津生物疗法有限公司 | 用于治疗癌症的针对ly75的偶联抗体 |
| US10709700B2 (en) | 2014-09-15 | 2020-07-14 | Orphazyme A/S | Arimoclomol formulation |
| NZ730490A (en) | 2014-10-09 | 2021-07-30 | Cedars Sinai Medical Center | Methods and systems for distinguishing irritable bowel syndrome from inflammatory bowel disease and celiac disease |
| CN108064166A (zh) * | 2014-10-23 | 2018-05-22 | 戊瑞治疗有限公司 | Slamf1拮抗剂及其用途 |
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| EP3442530A1 (en) | 2016-04-13 | 2019-02-20 | Orphazyme A/S | Heat shock proteins and cholesterol homeostasis |
| KR20210059796A (ko) | 2016-04-29 | 2021-05-25 | 오르파짐 에이/에스 | 글루코세레브로시다제 연관 장애를 치료하기 위한 아리모클로몰 |
| WO2018045155A1 (en) * | 2016-09-02 | 2018-03-08 | The Board Of Trustees Of The University Of Illinois | Kif13b-derived peptide and method of inhibiting angiogenesis |
| EP3573650A4 (en) | 2017-01-30 | 2020-12-09 | Cedars-Sinai Medical Center | DIAGNOSIS OF SCLERODERMIA |
| BR112020001653A2 (pt) | 2017-07-26 | 2020-07-21 | Forty Seven, Inc. | anticorpos anti-sirp-alfa e métodos relacionados |
| CN114126648A (zh) | 2019-05-31 | 2022-03-01 | Alx肿瘤生物技术公司 | 用SIRPα Fc融合体组合免疫检查点抑制剂治疗癌症的方法 |
| CN121243368A (zh) | 2019-11-27 | 2026-01-02 | Alx肿瘤生物技术公司 | 用于治疗癌症的组合疗法 |
| KR20230128462A (ko) | 2020-11-19 | 2023-09-05 | 제브라 덴마크 에이/에스 | 아리모클로몰 시트레이트 및 이의 중간체를 제조하기 위한 공정 |
| JP2024520902A (ja) | 2021-05-13 | 2024-05-27 | エーエルエックス オンコロジー インコーポレイテッド | がんを治療するための併用療法 |
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| AU2001243142A1 (en) * | 2000-02-03 | 2001-08-14 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
| US20040038339A1 (en) * | 2000-03-24 | 2004-02-26 | Peter Kufer | Multifunctional polypeptides comprising a binding site to an epitope of the nkg2d receptor complex |
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| AU2001274888A1 (en) * | 2000-05-19 | 2001-12-03 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| WO2001096372A2 (en) * | 2000-06-13 | 2001-12-20 | University College Cardiff Consultants Ltd | Zinc transporters proteins and their use in medicinal preparations |
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-
2003
- 2003-09-15 US US10/528,260 patent/US20070010434A1/en not_active Abandoned
- 2003-09-15 EP EP11189800A patent/EP2444409A2/en not_active Withdrawn
- 2003-09-15 JP JP2004536566A patent/JP2006515165A/ja not_active Withdrawn
- 2003-09-15 WO PCT/US2003/029097 patent/WO2004024097A2/en not_active Ceased
- 2003-09-15 EP EP03768511A patent/EP1578364A4/en not_active Withdrawn
- 2003-09-15 AU AU2003291625A patent/AU2003291625B2/en not_active Ceased
- 2003-09-15 CA CA002498274A patent/CA2498274A1/en not_active Abandoned
-
2008
- 2008-12-05 US US12/315,879 patent/US20090155263A1/en not_active Abandoned
-
2010
- 2010-01-07 AU AU2010200063A patent/AU2010200063B2/en not_active Ceased
- 2010-10-08 JP JP2010228397A patent/JP2011050389A/ja active Pending
- 2010-11-02 US US12/925,947 patent/US20110110938A1/en not_active Abandoned
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2011
- 2011-04-08 JP JP2011086366A patent/JP2011172580A/ja not_active Withdrawn
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