|
WO2010021720A1
(en)
|
2008-08-19 |
2010-02-25 |
Nektar Therapeutics |
Conjugates of small-interfering nucleic acids
|
|
TWI510246B
(zh)
|
2010-04-30 |
2015-12-01 |
Molecular Partners Ag |
抑制ｖｅｇｆ－ａ受體交互作用的經修飾結合性蛋白質
|
|
DK2643349T3
(da)
|
2010-11-26 |
2019-11-25 |
Molecular Partners Ag |
Designede repeat-proteiner, der binder til serumalbumin
|
|
WO2012112708A1
(en)
|
2011-02-15 |
2012-08-23 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives and methods of preparation
|
|
JP6209159B2
(ja)
|
2011-06-21 |
2017-10-04 |
イミュノジェン・インコーポレーテッド |
ペプチドリンカーを有する新規メイタンシノイド誘導体およびその結合体
|
|
EP2887965A1
(en)
|
2012-08-22 |
2015-07-01 |
ImmunoGen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
EP2738180A1
(en)
|
2012-11-30 |
2014-06-04 |
Molecular Partners AG |
Binding proteins comprising at least two binding domains against HER2.
|
|
WO2014134483A2
(en)
|
2013-02-28 |
2014-09-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
US9901647B2
(en)
|
2013-02-28 |
2018-02-27 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
WO2014194030A2
(en)
|
2013-05-31 |
2014-12-04 |
Immunogen, Inc. |
Conjugates comprising cell-binding agents and cytotoxic agents
|
|
US11453708B2
(en)
|
2013-05-31 |
2022-09-27 |
Molecular Partners Ag |
Designed ankyrin repeat proteins binding to hepatocyte growth factor
|
|
SG11201603228TA
(en)
|
2013-10-31 |
2016-05-30 |
Hutchinson Fred Cancer Res |
Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
|
|
PT3083671T
(pt)
|
2013-12-20 |
2020-12-24 |
Hutchinson Fred Cancer Res |
Moléculas efetoras quiméricas etiquetadas e recetores destas
|
|
CN106605228B
(zh)
|
2014-07-07 |
2019-08-16 |
耶达研究及发展有限公司 |
计算蛋白质设计的方法
|
|
US9381256B2
(en)
|
2014-09-03 |
2016-07-05 |
Immunogen, Inc. |
Cytotoxic benzodiazepine derivatives
|
|
ES2815353T3
(es)
|
2014-09-03 |
2021-03-29 |
Immunogen Inc |
Derivados de benzodiazepina citotóxicos
|
|
SG10201908203SA
(en)
|
2015-03-05 |
2019-10-30 |
Hutchinson Fred Cancer Res |
Immunomodulatory Fusion Proteins And Uses Thereof
|
|
PH12017501792B1
(en)
|
2015-04-02 |
2022-07-20 |
Molecular Partners Ag |
Recombinant binding proteins and their use
|
|
US11827904B2
(en)
|
2015-04-29 |
2023-11-28 |
Fred Hutchinson Cancer Center |
Modified stem cells and uses thereof
|
|
US20180355318A1
(en)
|
2015-04-29 |
2018-12-13 |
Fred Hutchinson Cancer Research Center |
Modified hematopoietic stem/progenitor and non-t effector cells, and uses thereof
|
|
WO2017106728A2
(en)
*
|
2015-12-16 |
2017-06-22 |
University Of Washington |
Repeat protein architectures
|
|
EP4166161A1
(en)
|
2016-04-14 |
2023-04-19 |
Fred Hutchinson Cancer Center |
Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers
|
|
AU2017331329B2
(en)
|
2016-09-22 |
2020-10-29 |
Molecular Partners Ag |
Recombinant binding proteins and their use
|
|
WO2018151836A1
(en)
|
2017-02-17 |
2018-08-23 |
Fred Hutchinson Cancer Research Center |
Combination therapies for treatment of bcma-related cancers and autoimmune disorders
|
|
TWI862991B
(zh)
|
2017-02-28 |
2024-11-21 |
美商伊繆諾金公司 |
具有自分解肽連接子之類美登素衍生物及其結合物
|
|
US11127483B2
(en)
|
2017-03-07 |
2021-09-21 |
Igc Bio, Inc. |
Computational pipeline for antibody modeling and design
|
|
WO2018170475A1
(en)
|
2017-03-17 |
2018-09-20 |
Fred Hutchinson Cancer Research Center |
Immunomodulatory fusion proteins and uses thereof
|
|
TW201839001A
(zh)
|
2017-04-20 |
2018-11-01 |
美商伊繆諾金公司 |
細胞毒性苯并二氮平衍生物及其綴合物
|
|
EP3732178A1
(en)
|
2017-12-28 |
2020-11-04 |
ImmunoGen, Inc. |
Benzodiazepine derivatives
|
|
EP3849565A4
(en)
|
2018-09-12 |
2022-12-28 |
Fred Hutchinson Cancer Research Center |
REDUCTION OF CD33 EXPRESSION TO SELECTIVELY PROTECT THERAPEUTIC CELLS
|
|
CN113631194A
(zh)
|
2019-03-21 |
2021-11-09 |
伊缪诺金公司 |
制备细胞结合剂-药物缀合物的方法
|
|
US20230094471A1
(en)
|
2019-03-29 |
2023-03-30 |
Immunogen, Inc. |
Cytotoxic bis-benzodiazepine derivatives and conjugates thereof with cell-binding agents for inhibiting abnormal cell growth or for treating proliferative diseases
|
|
HRP20231619T1
(hr)
|
2019-04-26 |
2024-04-26 |
Immunogen, Inc. |
Derivati kamptotecina
|
|
US20220298212A1
(en)
|
2019-06-04 |
2022-09-22 |
Molecular Partners Ag |
Recombinant 4-1bb binding proteins and their use
|
|
SG11202112925PA
(en)
|
2019-06-04 |
2021-12-30 |
Molecular Partners Ag |
Recombinant fap binding proteins and their use
|
|
JP7742309B2
(ja)
|
2019-06-04 |
2025-09-19 |
モレキュラー パートナーズ アクチェンゲゼルシャフト |
改善された安定性を有する設計されたアンキリン反復ドメイン
|
|
CN114729383A
(zh)
|
2019-07-02 |
2022-07-08 |
弗莱德哈钦森癌症研究中心 |
重组ad35载体及相关基因疗法改进
|
|
CN114945584A
(zh)
|
2019-12-11 |
2022-08-26 |
分子合作伙伴股份公司 |
重组肽-mhc复合物结合蛋白及其生成和用途
|
|
CN114929730A
(zh)
|
2019-12-11 |
2022-08-19 |
分子合作伙伴股份公司 |
重组肽-mhc复合物结合蛋白及其生成和用途
|
|
US20230142283A1
(en)
*
|
2020-03-05 |
2023-05-11 |
University Of Washington |
Rigid helical junctions for modular repeat protein sculpting and methods of use
|
|
WO2021224686A1
(en)
|
2020-05-06 |
2021-11-11 |
Molecular Partners Ag |
Novel ankyrin repeat binding proteins and their uses
|
|
WO2021229076A1
(en)
|
2020-05-14 |
2021-11-18 |
Molecular Partners Ag |
Recombinant cd40 binding proteins and their use
|
|
JP2023528204A
(ja)
|
2020-05-14 |
2023-07-04 |
モレキュラー パートナーズ アクチェンゲゼルシャフト |
多選択性タンパク質
|
|
US20240052033A1
(en)
|
2020-12-16 |
2024-02-15 |
Molecular Partners Ag |
Recombinant cd3 binding proteins and their use
|
|
WO2022130300A1
(en)
|
2020-12-16 |
2022-06-23 |
Molecular Partners Ag |
Novel slow-release prodrugs
|
|
KR20230155464A
(ko)
|
2021-03-09 |
2023-11-10 |
몰리큘라 파트너스 아게 |
신규한 DARPin-기반 다중특이성 T-세포 인게이저
|
|
AU2022232216A1
(en)
|
2021-03-09 |
2023-10-05 |
Molecular Partners Ag |
Protease cleavable prodrugs
|
|
JP2024508969A
(ja)
|
2021-03-09 |
2024-02-28 |
モレキュラー パートナーズ アクチェンゲゼルシャフト |
新規のＤＡＲＰｉｎに基づくＣＤ３３エンゲージャ
|
|
WO2022190018A1
(en)
|
2021-03-09 |
2022-09-15 |
Molecular Partners Ag |
Novel darpin based cd123 engagers
|
|
WO2023110983A1
(en)
|
2021-12-14 |
2023-06-22 |
Molecular Partners Ag |
Designed repeat domains with dual binding specificity and their use
|
|
EP4460511A1
(en)
*
|
2022-01-07 |
2024-11-13 |
Universität Zürich |
Stabilizing n-cap sequences for armadillo repeat proteins
|
|
WO2023215725A1
(en)
|
2022-05-02 |
2023-11-09 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
WO2024028278A1
(en)
|
2022-08-01 |
2024-02-08 |
Molecular Partners Ag |
Charge modified designed repeat domains and their use
|
|
WO2024179981A1
(en)
|
2023-02-27 |
2024-09-06 |
Molecular Partners Ag |
Darpins for use in reducing renal accumulation of drugs
|
|
WO2024251628A1
(en)
|
2023-06-06 |
2024-12-12 |
Molecular Partners Ag |
Recombinant cd16a binding proteins and their use
|
|
WO2024251695A1
(en)
|
2023-06-06 |
2024-12-12 |
Molecular Partners Ag |
Recombinant cd47 binding proteins and their use
|
|
WO2024251742A1
(en)
|
2023-06-06 |
2024-12-12 |
Molecular Partners Ag |
Recombinant cd2 binding proteins and their use
|
|
WO2025068607A1
(en)
*
|
2023-09-29 |
2025-04-03 |
Universität Zürich |
Modular armadillo repeat proteins
|
|
WO2025101820A1
(en)
|
2023-11-08 |
2025-05-15 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
WO2025146491A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Designed repeat domains with dual binding specificity for cd117 and cd47-binding agent
|
|
WO2025146490A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Recombinant cd117 binding proteins and their use
|
|
WO2025146487A1
(en)
|
2024-01-05 |
2025-07-10 |
Molecular Partners Ag |
Multispecific binding proteins
|
|
WO2025163082A1
(en)
|
2024-01-31 |
2025-08-07 |
Molecular Partners Ag |
Dll3-specific binding constructs and their use in radiotherapy
|
|
WO2025163144A1
(en)
|
2024-01-31 |
2025-08-07 |
Molecular Partners Ag |
Recombinant mesothelin binding proteins and their use
|
|
WO2025181039A1
(en)
|
2024-03-01 |
2025-09-04 |
Molecular Partners Ag |
Therapeutic combinations comprising a multi-specific t cell engager
|
|
WO2025245169A1
(en)
|
2024-05-21 |
2025-11-27 |
Fred Hutchinson Cancer Center |
Immunotherapy cells equipped with a collagen-targeting payload
|