JP2010539187A5 - - Google Patents

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Publication number
JP2010539187A5
JP2010539187A5 JP2010525103A JP2010525103A JP2010539187A5 JP 2010539187 A5 JP2010539187 A5 JP 2010539187A5 JP 2010525103 A JP2010525103 A JP 2010525103A JP 2010525103 A JP2010525103 A JP 2010525103A JP 2010539187 A5 JP2010539187 A5 JP 2010539187A5
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JP
Japan
Prior art keywords
group
dioxo
dihydropyrimidin
tert
butyl
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JP2010525103A
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English (en)
Japanese (ja)
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JP5734655B2 (ja
JP2010539187A (ja
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Priority claimed from PCT/US2008/076592 external-priority patent/WO2009039134A1/en
Publication of JP2010539187A publication Critical patent/JP2010539187A/ja
Publication of JP2010539187A5 publication Critical patent/JP2010539187A5/ja
Application granted granted Critical
Publication of JP5734655B2 publication Critical patent/JP5734655B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010525103A 2007-09-17 2008-09-17 抗感染症ピリミジンおよびその使用 Expired - Fee Related JP5734655B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US97288107P 2007-09-17 2007-09-17
US60/972,881 2007-09-17
US9679208P 2008-09-13 2008-09-13
US61/096,792 2008-09-13
PCT/US2008/076592 WO2009039134A1 (en) 2007-09-17 2008-09-17 Anti-infective pyrimidines and uses thereof

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2012221886A Division JP5931683B2 (ja) 2007-09-17 2012-10-04 抗感染症ピリミジンおよびその使用
JP2015082240A Division JP2015187106A (ja) 2007-09-17 2015-04-14 抗感染症ピリミジンおよびその使用

Publications (3)

Publication Number Publication Date
JP2010539187A JP2010539187A (ja) 2010-12-16
JP2010539187A5 true JP2010539187A5 (enExample) 2013-08-15
JP5734655B2 JP5734655B2 (ja) 2015-06-17

Family

ID=40308557

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2010525103A Expired - Fee Related JP5734655B2 (ja) 2007-09-17 2008-09-17 抗感染症ピリミジンおよびその使用
JP2012221886A Expired - Fee Related JP5931683B2 (ja) 2007-09-17 2012-10-04 抗感染症ピリミジンおよびその使用
JP2015082240A Pending JP2015187106A (ja) 2007-09-17 2015-04-14 抗感染症ピリミジンおよびその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2012221886A Expired - Fee Related JP5931683B2 (ja) 2007-09-17 2012-10-04 抗感染症ピリミジンおよびその使用
JP2015082240A Pending JP2015187106A (ja) 2007-09-17 2015-04-14 抗感染症ピリミジンおよびその使用

Country Status (21)

Country Link
US (3) US8188104B2 (enExample)
EP (3) EP2203431B1 (enExample)
JP (3) JP5734655B2 (enExample)
CN (4) CN104628654A (enExample)
AT (1) ATE519746T1 (enExample)
CA (2) CA2699986C (enExample)
CY (3) CY1115514T1 (enExample)
DK (3) DK2639226T3 (enExample)
ES (3) ES2368879T3 (enExample)
HR (2) HRP20110809T1 (enExample)
HU (1) HUS1500013I1 (enExample)
LT (1) LTC2203431I2 (enExample)
LU (1) LU92666I2 (enExample)
MX (1) MX2010002902A (enExample)
NL (1) NL300729I2 (enExample)
NO (1) NO2015011I1 (enExample)
PL (3) PL2203431T3 (enExample)
PT (3) PT2368882E (enExample)
RU (2) RU2014147354A (enExample)
SI (2) SI2368882T1 (enExample)
WO (1) WO2009039134A1 (enExample)

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EP2598480B1 (en) 2010-07-29 2019-04-24 Oryzon Genomics, S.A. Cyclopropylamine derivatives useful as lsd1 inhibitors
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WO2012072713A2 (en) * 2010-11-30 2012-06-07 Oryzon Genomics, S.A. Lysine demethylase inhibitors for diseases and disorders associated with flaviviridae
EP2712315B1 (en) 2011-02-08 2021-11-24 Oryzon Genomics, S.A. Lysine demethylase inhibitors for myeloproliferative disorders
CN102675092B (zh) * 2011-03-14 2014-11-05 江苏中丹药物研究有限公司 一种制备2-芳基-2,2-二甲基乙酸甲酯的方法
US10201584B1 (en) 2011-05-17 2019-02-12 Abbvie Inc. Compositions and methods for treating HCV
US9469597B2 (en) 2011-10-20 2016-10-18 Oryzon Genomics S.A. (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors
AU2012324803B9 (en) 2011-10-20 2017-08-24 Oryzon Genomics, S.A. (hetero)aryl cyclopropylamine compounds as LSD1 inhibitors
US8466159B2 (en) 2011-10-21 2013-06-18 Abbvie Inc. Methods for treating HCV
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US8492386B2 (en) 2011-10-21 2013-07-23 Abbvie Inc. Methods for treating HCV
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WO2014031791A1 (en) 2012-08-21 2014-02-27 Abbvie Inc. Process for preparing antiviral compounds
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CN106065009B (zh) * 2014-06-28 2019-03-01 广东东阳光药业有限公司 作为丙型肝炎抑制剂的化合物及其在药物中的应用
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PL3429352T3 (pl) * 2016-03-17 2022-08-22 Fmc Corporation Sposób konwersji enancjomeru-S do jego postaci racemicznej
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WO2017202207A1 (zh) * 2016-05-27 2017-11-30 深圳市塔吉瑞生物医药有限公司 一种取代的萘环化合物及药物组合物及其应用
CN110483496B (zh) * 2019-07-17 2021-05-04 杭州市西溪医院 一类具有尿嘧啶-苯并噻唑结构衍生物、其制备方法及抗hcv药物的应用
CN111518036A (zh) * 2020-04-29 2020-08-11 杭州勇诚睿生物科技有限公司 一种达沙布韦关键中间体的制备方法
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CN117466847B (zh) * 2022-07-22 2026-01-27 中国医药工业研究总院有限公司 一种利非斯特中间体苯并呋喃-6-羧酸的制备方法

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