JP2010536797A5 - - Google Patents
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- Publication number
- JP2010536797A5 JP2010536797A5 JP2010521229A JP2010521229A JP2010536797A5 JP 2010536797 A5 JP2010536797 A5 JP 2010536797A5 JP 2010521229 A JP2010521229 A JP 2010521229A JP 2010521229 A JP2010521229 A JP 2010521229A JP 2010536797 A5 JP2010536797 A5 JP 2010536797A5
- Authority
- JP
- Japan
- Prior art keywords
- formulation
- rapamycin
- ethanol
- human subject
- macular degeneration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96525807P | 2007-08-16 | 2007-08-16 | |
| US96528207P | 2007-08-16 | 2007-08-16 | |
| PCT/US2008/073520 WO2009023877A2 (en) | 2007-08-16 | 2008-08-18 | Formulations for treatment of ocular diseases or conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010536797A JP2010536797A (ja) | 2010-12-02 |
| JP2010536797A5 true JP2010536797A5 (https=) | 2013-07-25 |
Family
ID=40351498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010521229A Pending JP2010536797A (ja) | 2007-08-16 | 2008-08-18 | 眼の疾患または状態を治療するための製剤 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP2187743B1 (https=) |
| JP (1) | JP2010536797A (https=) |
| KR (1) | KR20100055482A (https=) |
| CN (1) | CN101827523A (https=) |
| ES (1) | ES2507078T3 (https=) |
| WO (1) | WO2009023877A2 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2471530B1 (en) | 2005-06-01 | 2017-01-11 | Edison Pharmaceuticals, Inc. | Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| US9278085B2 (en) | 2006-02-22 | 2016-03-08 | Edison Pharmaceuticals, Inc. | Side-chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
| PL2424495T3 (pl) | 2009-04-28 | 2018-06-29 | Bioelectron Technology Corporation | Leczenie dziedzicznej neuropatii nerwów wzrokowych lebera i dominującego zaniku nerwu wzrokowego chinonami tokotrienolu |
| EP2509596B1 (en) | 2009-12-08 | 2019-08-28 | Case Western Reserve University | Gamma aminoacids for treating ocular disorders |
| EP3501536B1 (en) * | 2011-10-13 | 2025-12-24 | EyePoint Pharmaceuticals, Inc. | Treatment of ocular disease |
| US8912215B2 (en) | 2011-12-13 | 2014-12-16 | Everon Biosciences, Inc. | Rapamycin composition |
| CN103239399B (zh) * | 2013-05-30 | 2016-06-29 | 山东兴瑞生物科技有限公司 | 一种西罗莫司纳米混悬剂及其制备方法 |
| KR101674457B1 (ko) * | 2013-11-04 | 2016-11-09 | 아주대학교산학협력단 | 다사티닙 또는 이의 약학적으로 허용되는 염을 유효성분으로 포함하는 혈관 투과성 관련 질환의 예방 또는 치료용 약학적 조성물 |
| RU2758335C2 (ru) * | 2015-02-02 | 2021-10-28 | Сантен Фармасьютикал Ко., Лтд | Композиция, способ трансдермальной доставки полиафрона, способ контролируемого высвобождения ингредиента |
| TWI731853B (zh) * | 2015-03-18 | 2021-07-01 | 日商參天製藥股份有限公司 | 徐放性醫藥組成物及其安定化方法 |
| JP6541124B2 (ja) * | 2015-03-23 | 2019-07-10 | 国立大学法人大阪大学 | びまん性神経線維腫用の外用薬 |
| JP6793651B2 (ja) * | 2015-08-28 | 2020-12-02 | 日本化薬株式会社 | ラパマイシン又はその誘導体を含有する医薬組成物 |
| JP6639364B2 (ja) * | 2015-09-18 | 2020-02-05 | 参天製薬株式会社 | 角膜真菌症の予防または治療剤 |
| RU2765728C2 (ru) * | 2016-05-25 | 2022-02-02 | Сантен Фармасьютикал Ко., Лтд. | Применение сиролимуса для лечения экссудативной возрастной макулярной дегенерации с персистирующим отеком |
| KR20190025635A (ko) * | 2016-06-30 | 2019-03-11 | 듀렉트 코퍼레이션 | 데포 제형 |
| WO2018125930A1 (en) * | 2016-12-27 | 2018-07-05 | University Of Utah Research Foundation | Intraocular drug delivery device and associated methods |
| JP7108631B2 (ja) | 2017-01-06 | 2022-07-28 | パルヴェラ セラピューティクス、インク. | mTOR阻害剤の無水組成物およびその使用方法 |
| EP3501496A1 (en) * | 2017-12-22 | 2019-06-26 | Cosmo Technologies Ltd. | Liquid delivery composition |
| US11648197B2 (en) | 2018-06-28 | 2023-05-16 | Arx, Llc | Dispensing method for producing dissolvable unit dose film constructs |
| US11000513B2 (en) | 2018-07-02 | 2021-05-11 | Palvella Therapeutics, Inc. | Anhydrous compositions of mTOR inhibitors and methods of use |
| CN109431997B (zh) * | 2018-12-20 | 2021-06-04 | 武汉科福新药有限责任公司 | 一种雷帕霉素局部注射制剂及其制备方法 |
| US20230055121A1 (en) * | 2019-12-26 | 2023-02-23 | Santen Pharmaceutical Co., Ltd. | Aqueous suspension composition containing sirolimus or salt thereof |
| CN112263670A (zh) * | 2020-10-22 | 2021-01-26 | 温州医科大学 | 硼替佐米及其制剂在制备治疗脉络膜新生血管性相关疾病药物上的应用及滴眼液制备方法 |
| EP4355349A4 (en) * | 2021-06-15 | 2025-04-16 | ONL Therapeutics, Inc. | Methods and compositions for treating eye diseases and disorders |
| CN115337263B (zh) * | 2022-08-09 | 2023-10-03 | 江苏汉晨药业有限公司 | 一种盐酸洛美沙星滴眼液 |
| CN115813863A (zh) * | 2022-12-15 | 2023-03-21 | 广州因明生物医药科技股份有限公司 | 一种可自发团聚的微球及其制备方法 |
| CN119258216A (zh) * | 2023-07-05 | 2025-01-07 | 沈阳兴齐眼药股份有限公司 | 眼用药物组合物、其制备方法、含其的眼用药盒及应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6599891B2 (en) * | 2001-07-20 | 2003-07-29 | Qlt Inc. | Treatment of macular edema |
| US8163726B2 (en) * | 2002-09-18 | 2012-04-24 | University Of Pennsylvania | Method of inhibiting choroidal neovascularization |
| US20040091455A1 (en) * | 2002-10-31 | 2004-05-13 | Zeldis Jerome B. | Methods of using and compositions comprising immunomodulatory compounds for treatment and management of macular degeneration |
| US7083802B2 (en) * | 2003-07-31 | 2006-08-01 | Advanced Ocular Systems Limited | Treatment of ocular disease |
| US20060182783A1 (en) * | 2004-04-30 | 2006-08-17 | Allergan, Inc. | Sustained release intraocular drug delivery systems |
| JP4974903B2 (ja) * | 2005-02-09 | 2012-07-11 | 参天製薬株式会社 | 疾患または状態を処置するための液体処方物 |
| US20060216288A1 (en) * | 2005-03-22 | 2006-09-28 | Amgen Inc | Combinations for the treatment of cancer |
-
2008
- 2008-08-18 WO PCT/US2008/073520 patent/WO2009023877A2/en not_active Ceased
- 2008-08-18 ES ES08827362.8T patent/ES2507078T3/es active Active
- 2008-08-18 CN CN200880112404A patent/CN101827523A/zh active Pending
- 2008-08-18 KR KR1020107005823A patent/KR20100055482A/ko not_active Ceased
- 2008-08-18 JP JP2010521229A patent/JP2010536797A/ja active Pending
- 2008-08-18 EP EP08827362.8A patent/EP2187743B1/en not_active Not-in-force
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