JP2010536797A5 - - Google Patents

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Publication number
JP2010536797A5
JP2010536797A5 JP2010521229A JP2010521229A JP2010536797A5 JP 2010536797 A5 JP2010536797 A5 JP 2010536797A5 JP 2010521229 A JP2010521229 A JP 2010521229A JP 2010521229 A JP2010521229 A JP 2010521229A JP 2010536797 A5 JP2010536797 A5 JP 2010536797A5
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JP
Japan
Prior art keywords
formulation
rapamycin
ethanol
human subject
macular degeneration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010521229A
Other languages
English (en)
Japanese (ja)
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JP2010536797A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/073520 external-priority patent/WO2009023877A2/en
Publication of JP2010536797A publication Critical patent/JP2010536797A/ja
Publication of JP2010536797A5 publication Critical patent/JP2010536797A5/ja
Pending legal-status Critical Current

Links

JP2010521229A 2007-08-16 2008-08-18 眼の疾患または状態を治療するための製剤 Pending JP2010536797A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96525807P 2007-08-16 2007-08-16
US96528207P 2007-08-16 2007-08-16
PCT/US2008/073520 WO2009023877A2 (en) 2007-08-16 2008-08-18 Formulations for treatment of ocular diseases or conditions

Publications (2)

Publication Number Publication Date
JP2010536797A JP2010536797A (ja) 2010-12-02
JP2010536797A5 true JP2010536797A5 (https=) 2013-07-25

Family

ID=40351498

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010521229A Pending JP2010536797A (ja) 2007-08-16 2008-08-18 眼の疾患または状態を治療するための製剤

Country Status (6)

Country Link
EP (1) EP2187743B1 (https=)
JP (1) JP2010536797A (https=)
KR (1) KR20100055482A (https=)
CN (1) CN101827523A (https=)
ES (1) ES2507078T3 (https=)
WO (1) WO2009023877A2 (https=)

Families Citing this family (27)

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Publication number Priority date Publication date Assignee Title
EP2471530B1 (en) 2005-06-01 2017-01-11 Edison Pharmaceuticals, Inc. Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
US9278085B2 (en) 2006-02-22 2016-03-08 Edison Pharmaceuticals, Inc. Side-chain variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
PL2424495T3 (pl) 2009-04-28 2018-06-29 Bioelectron Technology Corporation Leczenie dziedzicznej neuropatii nerwów wzrokowych lebera i dominującego zaniku nerwu wzrokowego chinonami tokotrienolu
EP2509596B1 (en) 2009-12-08 2019-08-28 Case Western Reserve University Gamma aminoacids for treating ocular disorders
EP3501536B1 (en) * 2011-10-13 2025-12-24 EyePoint Pharmaceuticals, Inc. Treatment of ocular disease
US8912215B2 (en) 2011-12-13 2014-12-16 Everon Biosciences, Inc. Rapamycin composition
CN103239399B (zh) * 2013-05-30 2016-06-29 山东兴瑞生物科技有限公司 一种西罗莫司纳米混悬剂及其制备方法
KR101674457B1 (ko) * 2013-11-04 2016-11-09 아주대학교산학협력단 다사티닙 또는 이의 약학적으로 허용되는 염을 유효성분으로 포함하는 혈관 투과성 관련 질환의 예방 또는 치료용 약학적 조성물
RU2758335C2 (ru) * 2015-02-02 2021-10-28 Сантен Фармасьютикал Ко., Лтд Композиция, способ трансдермальной доставки полиафрона, способ контролируемого высвобождения ингредиента
TWI731853B (zh) * 2015-03-18 2021-07-01 日商參天製藥股份有限公司 徐放性醫藥組成物及其安定化方法
JP6541124B2 (ja) * 2015-03-23 2019-07-10 国立大学法人大阪大学 びまん性神経線維腫用の外用薬
JP6793651B2 (ja) * 2015-08-28 2020-12-02 日本化薬株式会社 ラパマイシン又はその誘導体を含有する医薬組成物
JP6639364B2 (ja) * 2015-09-18 2020-02-05 参天製薬株式会社 角膜真菌症の予防または治療剤
RU2765728C2 (ru) * 2016-05-25 2022-02-02 Сантен Фармасьютикал Ко., Лтд. Применение сиролимуса для лечения экссудативной возрастной макулярной дегенерации с персистирующим отеком
KR20190025635A (ko) * 2016-06-30 2019-03-11 듀렉트 코퍼레이션 데포 제형
WO2018125930A1 (en) * 2016-12-27 2018-07-05 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
JP7108631B2 (ja) 2017-01-06 2022-07-28 パルヴェラ セラピューティクス、インク. mTOR阻害剤の無水組成物およびその使用方法
EP3501496A1 (en) * 2017-12-22 2019-06-26 Cosmo Technologies Ltd. Liquid delivery composition
US11648197B2 (en) 2018-06-28 2023-05-16 Arx, Llc Dispensing method for producing dissolvable unit dose film constructs
US11000513B2 (en) 2018-07-02 2021-05-11 Palvella Therapeutics, Inc. Anhydrous compositions of mTOR inhibitors and methods of use
CN109431997B (zh) * 2018-12-20 2021-06-04 武汉科福新药有限责任公司 一种雷帕霉素局部注射制剂及其制备方法
US20230055121A1 (en) * 2019-12-26 2023-02-23 Santen Pharmaceutical Co., Ltd. Aqueous suspension composition containing sirolimus or salt thereof
CN112263670A (zh) * 2020-10-22 2021-01-26 温州医科大学 硼替佐米及其制剂在制备治疗脉络膜新生血管性相关疾病药物上的应用及滴眼液制备方法
EP4355349A4 (en) * 2021-06-15 2025-04-16 ONL Therapeutics, Inc. Methods and compositions for treating eye diseases and disorders
CN115337263B (zh) * 2022-08-09 2023-10-03 江苏汉晨药业有限公司 一种盐酸洛美沙星滴眼液
CN115813863A (zh) * 2022-12-15 2023-03-21 广州因明生物医药科技股份有限公司 一种可自发团聚的微球及其制备方法
CN119258216A (zh) * 2023-07-05 2025-01-07 沈阳兴齐眼药股份有限公司 眼用药物组合物、其制备方法、含其的眼用药盒及应用

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
US6599891B2 (en) * 2001-07-20 2003-07-29 Qlt Inc. Treatment of macular edema
US8163726B2 (en) * 2002-09-18 2012-04-24 University Of Pennsylvania Method of inhibiting choroidal neovascularization
US20040091455A1 (en) * 2002-10-31 2004-05-13 Zeldis Jerome B. Methods of using and compositions comprising immunomodulatory compounds for treatment and management of macular degeneration
US7083802B2 (en) * 2003-07-31 2006-08-01 Advanced Ocular Systems Limited Treatment of ocular disease
US20060182783A1 (en) * 2004-04-30 2006-08-17 Allergan, Inc. Sustained release intraocular drug delivery systems
JP4974903B2 (ja) * 2005-02-09 2012-07-11 参天製薬株式会社 疾患または状態を処置するための液体処方物
US20060216288A1 (en) * 2005-03-22 2006-09-28 Amgen Inc Combinations for the treatment of cancer

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