JP2010536719A5 - - Google Patents

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Publication number
JP2010536719A5
JP2010536719A5 JP2010520440A JP2010520440A JP2010536719A5 JP 2010536719 A5 JP2010536719 A5 JP 2010536719A5 JP 2010520440 A JP2010520440 A JP 2010520440A JP 2010520440 A JP2010520440 A JP 2010520440A JP 2010536719 A5 JP2010536719 A5 JP 2010536719A5
Authority
JP
Japan
Prior art keywords
tumors
group
leukemia
head
chronic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010520440A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010536719A (ja
Filing date
Publication date
Priority claimed from DE102007038957A external-priority patent/DE102007038957A1/de
Application filed filed Critical
Publication of JP2010536719A publication Critical patent/JP2010536719A/ja
Publication of JP2010536719A5 publication Critical patent/JP2010536719A5/ja
Pending legal-status Critical Current

Links

JP2010520440A 2007-08-17 2008-07-18 ６−チオキソピリダジン誘導体 Pending JP2010536719A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007038957A DE102007038957A1 (de) 2007-08-17 2007-08-17 6-Thioxo-pyridazinderivate
PCT/EP2008/005928 WO2009024221A1 (de) 2007-08-17 2008-07-18 6-thioxo-pyridazinderivate

Publications (2)

Publication Number Publication Date
JP2010536719A JP2010536719A (ja) 2010-12-02
JP2010536719A5 true JP2010536719A5 (enExample) 2011-09-08

Family

ID=40029265

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010520440A Pending JP2010536719A (ja) 2007-08-17 2008-07-18 ６−チオキソピリダジン誘導体

Country Status (7)

Country Link
US (1) US20110136819A1 (enExample)
EP (1) EP2176236A1 (enExample)
JP (1) JP2010536719A (enExample)
AU (1) AU2008290896A1 (enExample)
CA (1) CA2696472A1 (enExample)
DE (1) DE102007038957A1 (enExample)
WO (1) WO2009024221A1 (enExample)

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DE102007061963A1 (de) * 2007-12-21 2009-06-25 Merck Patent Gmbh Pyridazinonderivate
JP2013532627A (ja) 2010-07-01 2013-08-19 武田薬品工業株式会社 ｃＭＥＴ阻害剤とＨＧＦおよび／またはｃＭＥＴに対する抗体との組み合わせ
JP2013536802A (ja) * 2010-08-31 2013-09-26 メルク・シャープ・エンド・ドーム・コーポレイション チロシンキナーゼ阻害剤
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
WO2014080291A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Biaryl derivatives as bromodomain inhibitors
US9271978B2 (en) 2012-12-21 2016-03-01 Zenith Epigenetics Corp. Heterocyclic compounds as bromodomain inhibitors
SG11201510409QA (en) 2013-06-21 2016-01-28 Zenith Epigenetics Corp Novel bicyclic bromodomain inhibitors
WO2015004533A2 (en) 2013-06-21 2015-01-15 Zenith Epigenetics Corp. Novel substituted bicyclic compounds as bromodomain inhibitors
AU2014298051B2 (en) 2013-07-31 2018-11-15 Zenith Epigenetics Ltd. Novel quinazolinones as bromodomain inhibitors
WO2016087936A1 (en) 2014-12-01 2016-06-09 Zenith Epigenetics Corp. Substituted pyridinones as bromodomain inhibitors
WO2016087942A1 (en) 2014-12-01 2016-06-09 Zenith Epigenetics Corp. Substituted pyridines as bromodomain inhibitors
EP3229836B1 (en) 2014-12-09 2019-11-13 Institut National de la Sante et de la Recherche Medicale (INSERM) Human monoclonal antibodies against axl
CN107207474B (zh) 2014-12-11 2021-05-07 恒翼生物医药科技(上海)有限公司 被取代的杂环作为溴结构域抑制剂
CA2966450A1 (en) 2014-12-17 2016-06-23 Olesya KHARENKO Inhibitors of bromodomains
WO2016135041A1 (en) 2015-02-26 2016-09-01 INSERM (Institut National de la Santé et de la Recherche Médicale) Fusion proteins and antibodies comprising thereof for promoting apoptosis
AU2019374812B2 (en) 2018-11-06 2025-03-06 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
KR102885525B1 (ko) 2018-11-06 2025-11-13 엣지와이즈 테라퓨틱스, 인크. 피리다지논 화합물 및 이의 용도
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CA3200234A1 (en) 2020-11-25 2022-06-02 Daryl C. Drummond Lipid nanoparticles for delivery of nucleic acids, and related methods of use
EP4531819A2 (en) 2022-05-25 2025-04-09 Akagera Medicines, Inc. Lipid nanoparticles for delivery of nucleic acids and methods of use thereof
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