JP2010536043A5 - - Google Patents
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- Publication number
- JP2010536043A5 JP2010536043A5 JP2010520409A JP2010520409A JP2010536043A5 JP 2010536043 A5 JP2010536043 A5 JP 2010536043A5 JP 2010520409 A JP2010520409 A JP 2010520409A JP 2010520409 A JP2010520409 A JP 2010520409A JP 2010536043 A5 JP2010536043 A5 JP 2010536043A5
- Authority
- JP
- Japan
- Prior art keywords
- gelsolin
- polypeptide
- subject
- level
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920001184 polypeptide Polymers 0.000 claims 22
- 102000004196 processed proteins & peptides Human genes 0.000 claims 22
- 108090000765 processed proteins & peptides Proteins 0.000 claims 22
- 238000000034 method Methods 0.000 claims 20
- 102000004878 Gelsolin Human genes 0.000 claims 5
- 108090001064 Gelsolin Proteins 0.000 claims 5
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 208000001647 Renal Insufficiency Diseases 0.000 claims 2
- 230000000890 antigenic effect Effects 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 210000004408 hybridoma Anatomy 0.000 claims 2
- 201000006370 kidney failure Diseases 0.000 claims 2
- 238000012544 monitoring process Methods 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- 210000002700 urine Anatomy 0.000 claims 2
- 206010008909 Chronic Hepatitis Diseases 0.000 claims 1
- 238000002965 ELISA Methods 0.000 claims 1
- 208000010718 Multiple Organ Failure Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 206010040070 Septic Shock Diseases 0.000 claims 1
- 208000006011 Stroke Diseases 0.000 claims 1
- 208000018359 Systemic autoimmune disease Diseases 0.000 claims 1
- 210000004900 c-terminal fragment Anatomy 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 238000002512 chemotherapy Methods 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 208000006454 hepatitis Diseases 0.000 claims 1
- 230000008105 immune reaction Effects 0.000 claims 1
- 208000029744 multiple organ dysfunction syndrome Diseases 0.000 claims 1
- 208000010125 myocardial infarction Diseases 0.000 claims 1
- 238000001959 radiotherapy Methods 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 230000036303 septic shock Effects 0.000 claims 1
- 230000004083 survival effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2007/002467 WO2009021360A1 (en) | 2007-08-15 | 2007-08-15 | Gelsolin binding agent compositions and uses of same |
| PCT/CN2008/072005 WO2009024070A1 (en) | 2007-08-15 | 2008-08-15 | Detection and quantitation of urine gelsolin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010536043A JP2010536043A (ja) | 2010-11-25 |
| JP2010536043A5 true JP2010536043A5 (enExample) | 2011-03-24 |
Family
ID=40350342
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010520397A Pending JP2010537625A (ja) | 2007-08-15 | 2007-08-15 | ゲルゾリン結合剤組成物およびその使用 |
| JP2010520409A Pending JP2010536043A (ja) | 2007-08-15 | 2008-08-15 | 尿ゲルゾリンの検出および定量化 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010520397A Pending JP2010537625A (ja) | 2007-08-15 | 2007-08-15 | ゲルゾリン結合剤組成物およびその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8367356B2 (enExample) |
| EP (2) | EP2188309A4 (enExample) |
| JP (2) | JP2010537625A (enExample) |
| CN (2) | CN102119173B (enExample) |
| WO (2) | WO2009021360A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2535718B1 (en) | 2007-05-11 | 2014-07-09 | The Institutes for Pharmaceutical Discovery, LLC | Methods for early diagnosis of kidney disease |
| CN102119173B (zh) * | 2007-08-15 | 2015-04-08 | 北京同为时代生物技术有限公司 | 凝溶胶蛋白结合剂组合物及其用途 |
| US20100136610A1 (en) * | 2008-12-03 | 2010-06-03 | Jeong-Yeol Yoon | Methods And Microfluidic Devices For Single Cell Detection Of Escherichia Coli |
| US9562855B1 (en) | 2009-12-03 | 2017-02-07 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Devices and methods for detection of microorganisms via MIE scattering |
| US9678005B1 (en) | 2008-12-03 | 2017-06-13 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Devices and methods for detection of microorganisms |
| EP2725360A1 (en) * | 2012-10-24 | 2014-04-30 | Fundació Hospital Universitari Vall d' Hebron - Institut de Recerca | Biomarkers for the prognosis of ischemic stroke |
| WO2016054383A1 (en) * | 2014-10-01 | 2016-04-07 | Henry Ford Health System | Methods for treating sepsis and biomarkers related thereto |
| FR3036188B1 (fr) * | 2015-05-12 | 2019-06-07 | Biomerieux | Prediction du risque de developper, pour des patients admis en service de reanimation, une infection disseminee |
| CN108020663A (zh) * | 2016-11-02 | 2018-05-11 | 张曼 | 尿液凝溶胶蛋白及其多肽片段在肺腺癌中的应用 |
| US10905585B1 (en) | 2020-02-21 | 2021-02-02 | Robert Sabin | Respiratory therapeutic electric heat source face mask |
| AU2021268600A1 (en) * | 2020-05-04 | 2022-12-08 | Bioaegis Therapeutics Inc. | Compositions comprising gelsolin for treating frailty |
| US20230357388A1 (en) * | 2020-09-25 | 2023-11-09 | The Francis Crick Institute Limited | Immunotherapy |
| CN115308010B (zh) * | 2021-05-06 | 2025-05-23 | 威高集团有限公司 | 一种抗体保护剂和采血管 |
| WO2024087613A1 (zh) | 2022-10-24 | 2024-05-02 | 浙江宇龙药业有限公司 | 一种含七氟异丙基的双酰胺类化合物及其中间体化合物，其制备方法与用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5650487A (en) | 1988-09-09 | 1997-07-22 | The Regents Of The University Of California | Serum immunoregulatory polypeptides and uses therefor |
| WO1994003601A2 (en) | 1992-08-03 | 1994-02-17 | New York University | Cloning, expression and uses for neurocan as a chondroitin sulfate proteoglycan |
| JP3914272B2 (ja) * | 1993-12-28 | 2007-05-16 | 中外製薬株式会社 | アドゼベリンをコードする遺伝子 |
| WO2005014635A2 (en) | 2003-07-15 | 2005-02-17 | Genova Ltd. | Secreted polypeptide species reduced in cardiovascular disorders |
| ES2848385T3 (es) * | 2003-11-12 | 2021-08-09 | Univ Pennsylvania | Métodos de uso de gelsolina para tratar o prevenir septicemia bacteriana |
| CN1746676A (zh) * | 2004-09-08 | 2006-03-15 | 中国医学科学院肿瘤医院肿瘤研究所 | 一种胰腺癌血清标志分子的检测方法 |
| WO2006091861A2 (en) | 2005-02-25 | 2006-08-31 | Ppd Biomarker Discovery Sciences, Llc | Compositions and methods relating to cns lymphoma |
| AU2007227613A1 (en) * | 2006-03-15 | 2007-09-27 | The Brigham And Women's Hospital, Inc. | Use of gelsolin to diagnose and treat inflammatory diseases |
| WO2007137582A1 (en) | 2006-05-30 | 2007-12-06 | Antibodyshop A/S | Methods and devices for rapid assessment of severity of injury and disease |
| CN102119173B (zh) * | 2007-08-15 | 2015-04-08 | 北京同为时代生物技术有限公司 | 凝溶胶蛋白结合剂组合物及其用途 |
-
2007
- 2007-08-15 CN CN200780101031.4A patent/CN102119173B/zh not_active Expired - Fee Related
- 2007-08-15 US US12/673,134 patent/US8367356B2/en not_active Expired - Fee Related
- 2007-08-15 EP EP07785362A patent/EP2188309A4/en not_active Withdrawn
- 2007-08-15 JP JP2010520397A patent/JP2010537625A/ja active Pending
- 2007-08-15 WO PCT/CN2007/002467 patent/WO2009021360A1/en not_active Ceased
-
2008
- 2008-08-15 WO PCT/CN2008/072005 patent/WO2009024070A1/en not_active Ceased
- 2008-08-15 EP EP08783996A patent/EP2188304A4/en not_active Withdrawn
- 2008-08-15 JP JP2010520409A patent/JP2010536043A/ja active Pending
- 2008-08-15 US US12/673,139 patent/US20120156700A1/en not_active Abandoned
- 2008-08-15 CN CN200880110871.1A patent/CN101855236B/zh not_active Expired - Fee Related