|
US578192A
(en)
*
|
|
1897-03-02 |
|
Henry h |
|
US4331647A
(en)
|
1980-03-03 |
1982-05-25 |
Goldenberg Milton David |
Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
|
|
AU560472B2
(en)
|
1981-08-25 |
1987-04-09 |
Celltech Limited |
Yeast expression vectors
|
|
US4486533A
(en)
|
1982-09-02 |
1984-12-04 |
St. Louis University |
Filamentous fungi functional replicating extrachromosomal element
|
|
US4599311A
(en)
|
1982-08-13 |
1986-07-08 |
Kawasaki Glenn H |
Glycolytic promotersfor regulated protein expression: protease inhibitor
|
|
US4977092A
(en)
|
1985-06-26 |
1990-12-11 |
Amgen |
Expression of exogenous polypeptides and polypeptide products including hepatitis B surface antigen in yeast cells
|
|
US4603044A
(en)
|
1983-01-06 |
1986-07-29 |
Technology Unlimited, Inc. |
Hepatocyte Directed Vesicle delivery system
|
|
US4661454A
(en)
|
1983-02-28 |
1987-04-28 |
Collaborative Research, Inc. |
GAL1 yeast promoter linked to non galactokinase gene
|
|
US5139936A
(en)
|
1983-02-28 |
1992-08-18 |
Collaborative Research, Inc. |
Use of the GAL1 yeast promoter
|
|
US4870008A
(en)
|
1983-08-12 |
1989-09-26 |
Chiron Corporation |
Secretory expression in eukaryotes
|
|
EP0154316B1
(en)
|
1984-03-06 |
1989-09-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified lymphokine and production thereof
|
|
US4931373A
(en)
|
1984-05-25 |
1990-06-05 |
Zymogenetics, Inc. |
Stable DNA constructs for expression of α-1 antitrypsin
|
|
US4766073A
(en)
|
1985-02-25 |
1988-08-23 |
Zymogenetics Inc. |
Expression of biologically active PDGF analogs in eucaryotic cells
|
|
EP0184576B1
(en)
|
1984-12-06 |
1990-06-27 |
Fina Research S.A. |
Promoters for the expression of foreign genes in yeast, plasmids comprising them, and uses thereof for the production of polypeptides
|
|
DE3546807C2
(enExample)
|
1985-03-30 |
1991-03-28 |
Marc Genf/Geneve Ch Ballivet |
|
|
US4882279A
(en)
|
1985-10-25 |
1989-11-21 |
Phillips Petroleum Company |
Site selective genomic modification of yeast of the genus pichia
|
|
US4935349A
(en)
|
1986-01-17 |
1990-06-19 |
Zymogenetics, Inc. |
Expression of higher eucaryotic genes in aspergillus
|
|
GB8611832D0
(en)
|
1986-05-15 |
1986-06-25 |
Holland I B |
Polypeptide
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
US5063154A
(en)
|
1987-06-24 |
1991-11-05 |
Whitehead Institute For Biomedical Research |
Pheromone - inducible yeast promoter
|
|
US5637677A
(en)
|
1987-07-16 |
1997-06-10 |
The Trustees Of The University Of Pennsylvania |
Biologically active compounds and methods of constructing and using the same
|
|
WO1989004838A1
(en)
*
|
1987-11-25 |
1989-06-01 |
Immunex Corporation |
Interleukin-1 receptors
|
|
US5750375A
(en)
|
1988-01-22 |
1998-05-12 |
Zymogenetics, Inc. |
Methods of producing secreted receptor analogs and biologically active dimerized polypeptide fusions
|
|
EP0721983A1
(en)
|
1988-01-22 |
1996-07-17 |
ZymoGenetics, Inc. |
Methods of producing biologically active peptide dimers
|
|
US5567584A
(en)
|
1988-01-22 |
1996-10-22 |
Zymogenetics, Inc. |
Methods of using biologically active dimerized polypeptide fusions to detect PDGF
|
|
US6018026A
(en)
|
1988-01-22 |
2000-01-25 |
Zymogenetics, Inc. |
Biologically active dimerized and multimerized polypeptide fusions
|
|
US5037743A
(en)
|
1988-08-05 |
1991-08-06 |
Zymogenetics, Inc. |
BAR1 secretion signal
|
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
US5162228A
(en)
|
1988-12-28 |
1992-11-10 |
Takeda Chemical Industries, Ltd. |
Gylceraldehyde-3-phosphate dehydrogenase gene and promoter
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
SG46445A1
(en)
|
1990-01-26 |
1998-02-20 |
Immunomedics Inc |
Vaccines against cancer and infectious diseases
|
|
US5747334A
(en)
|
1990-02-15 |
1998-05-05 |
The University Of North Carolina At Chapel Hill |
Random peptide library
|
|
IL99552A0
(en)
|
1990-09-28 |
1992-08-18 |
Ixsys Inc |
Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
|
|
US5208146A
(en)
|
1990-11-05 |
1993-05-04 |
The Regents Of The University Of California |
Murine monoclonal anti-idiotype antibodies
|
|
US5252714A
(en)
|
1990-11-28 |
1993-10-12 |
The University Of Alabama In Huntsville |
Preparation and use of polyethylene glycol propionaldehyde
|
|
JP3202999B2
(ja)
|
1991-01-31 |
2001-08-27 |
協和醗酵工業株式会社 |
肝移行性リポソーム製剤
|
|
US5298418A
(en)
|
1991-09-16 |
1994-03-29 |
Boyce Thompson Institute For Plant Research, Inc. |
Cell line isolated from larval midgut tissue of Trichoplusia ni
|
|
US5436155A
(en)
*
|
1991-12-31 |
1995-07-25 |
Arch Development Corporation |
Isolated DNA encoding a somatostatin receptor
|
|
US5783384A
(en)
|
1992-01-13 |
1998-07-21 |
President And Fellows Of Harvard College |
Selection of binding-molecules
|
|
US5382657A
(en)
|
1992-08-26 |
1995-01-17 |
Hoffmann-La Roche Inc. |
Peg-interferon conjugates
|
|
WO1995021258A1
(en)
|
1994-02-01 |
1995-08-10 |
United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Fusion proteins that include antibody and nonantibody portions
|
|
US6117679A
(en)
|
1994-02-17 |
2000-09-12 |
Maxygen, Inc. |
Methods for generating polynucleotides having desired characteristics by iterative selection and recombination
|
|
US5738846A
(en)
|
1994-11-10 |
1998-04-14 |
Enzon, Inc. |
Interferon polymer conjugates and process for preparing the same
|
|
US5641655A
(en)
|
1994-11-30 |
1997-06-24 |
Zymogenetics, Inc. |
Methods for producing thrombopoietin polypeptides using a mammalian tissue plasminogen activator secretory peptide
|
|
WO1997017450A2
(en)
|
1995-11-09 |
1997-05-15 |
Zymogenetics, Inc. |
Compositions and methods for producing heterologous polypeptides in pichia methanolica
|
|
US5716808A
(en)
|
1995-11-09 |
1998-02-10 |
Zymogenetics, Inc. |
Genetic engineering of pichia methanolica
|
|
US5723125A
(en)
|
1995-12-28 |
1998-03-03 |
Tanox Biosystems, Inc. |
Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide
|
|
US5736383A
(en)
|
1996-08-26 |
1998-04-07 |
Zymogenetics, Inc. |
Preparation of Pichia methanolica auxotrophic mutants
|
|
CN1238806A
(zh)
|
1996-07-17 |
1999-12-15 |
津莫吉尼蒂克斯公司 |
甲醇毕赤酵母营养突变体的制备
|
|
WO1998002565A1
(en)
|
1996-07-17 |
1998-01-22 |
Zymogenetics, Inc. |
TRANSFORMATION OF $i(PICHIA METHANOLICA)
|
|
US5985614A
(en)
*
|
1996-08-30 |
1999-11-16 |
Human Genome Sciences, Inc. |
Polynucleotides encoding interleukin-19
|
|
US5945511A
(en)
*
|
1997-02-20 |
1999-08-31 |
Zymogenetics, Inc. |
Class II cytokine receptor
|
|
US6486301B1
(en)
*
|
1997-07-16 |
2002-11-26 |
Human Genome Sciences, Inc. |
Interleukin-20
|
|
US5965704A
(en)
*
|
1997-08-05 |
1999-10-12 |
Zymogenetics, Inc. |
Class two cytokine receptor-11
|
|
US6020163A
(en)
*
|
1997-08-06 |
2000-02-01 |
Zymogenetics, Inc. |
Lipocalin homolog
|
|
US6576743B1
(en)
*
|
1997-11-26 |
2003-06-10 |
Zymogenetics, Inc. |
Mammalian cytokine-like polypeptide-10
|
|
CN1618969A
(zh)
|
1997-11-26 |
2005-05-25 |
津莫吉尼蒂克斯公司 |
哺乳动物细胞因子样多肽－10
|
|
US6274710B1
(en)
*
|
1998-10-26 |
2001-08-14 |
Ludwig Institute For Cancer Research |
Antibodies which specifically bind T Cell inducible factors (TIFs)
|
|
BR9914777A
(pt)
|
1998-10-26 |
2001-07-03 |
Ludwig Inst Cancer Res |
Moléculas isoladas de ácido nucléico que codificam os fatores induzìveis por células t (tifs), as proteìnas codificadas e os usos das mesmas
|
|
CA2393369A1
(en)
*
|
1999-12-03 |
2001-06-07 |
Zymogenetics, Inc. |
Human cytokine receptor
|
|
DE60045139D1
(de)
|
1999-12-23 |
2010-12-02 |
Zymogenetics Inc |
Löslicher Interleukin-20-Rezeptor
|
|
US6610286B2
(en)
*
|
1999-12-23 |
2003-08-26 |
Zymogenetics, Inc. |
Method for treating inflammation using soluble receptors to interleukin-20
|
|
EP2177616B1
(en)
|
2000-08-08 |
2012-02-29 |
ZymoGenetics, Inc. |
Soluble zcytor 11 cytokine receptors
|
|
EP1803733B1
(en)
*
|
2000-09-15 |
2010-03-10 |
ZymoGenetics, Inc. |
Polypeptides comprising the extracellular domains of IL-20RA and/or IL-20RB
|
|
US20030022827A1
(en)
*
|
2000-09-25 |
2003-01-30 |
Bertram Weiss |
Three new members of the cytokine receptor family class 2
|
|
CA2438238A1
(en)
|
2001-02-23 |
2002-09-06 |
Genetics Institute, Llc. |
Composition comprising il-22 inhibitors and use thereof for treating inflammatory disorders
|
|
WO2002070655A2
(en)
*
|
2001-03-02 |
2002-09-12 |
Zymogenetics, Inc. |
Mouse cytokine receptor
|
|
DK1399472T3
(da)
|
2001-03-09 |
2009-10-05 |
Zymogenetics Inc |
Oplöselig heterodimer cytokinreceptor
|
|
EP1606317B1
(en)
*
|
2003-03-24 |
2010-07-28 |
ZymoGenetics, Inc. |
Anti-il-22ra antibodies and binding partners and methods of using in inflammation
|
|
EP2143733A1
(en)
*
|
2003-11-21 |
2010-01-13 |
ZymoGenetics, Inc. |
ANTI-IL-20 antibodies and binding partners and methods of using in inflammation
|