JP2010535704A5 - - Google Patents

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Publication number
JP2010535704A5
JP2010535704A5 JP2010504096A JP2010504096A JP2010535704A5 JP 2010535704 A5 JP2010535704 A5 JP 2010535704A5 JP 2010504096 A JP2010504096 A JP 2010504096A JP 2010504096 A JP2010504096 A JP 2010504096A JP 2010535704 A5 JP2010535704 A5 JP 2010535704A5
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JP
Japan
Prior art keywords
group
atom
halogen atom
hydroxy
lower alkyl
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JP2010504096A
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English (en)
Japanese (ja)
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JP5292390B2 (ja
JP2010535704A (ja
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Priority to JP2010504096A priority Critical patent/JP5292390B2/ja
Priority claimed from JP2010504096A external-priority patent/JP5292390B2/ja
Publication of JP2010535704A publication Critical patent/JP2010535704A/ja
Publication of JP2010535704A5 publication Critical patent/JP2010535704A5/ja
Application granted granted Critical
Publication of JP5292390B2 publication Critical patent/JP5292390B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010504096A 2007-08-07 2008-08-06 アンドロゲン受容体調節剤としてのピロリジン−２−オン誘導体 Expired - Fee Related JP5292390B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2010504096A JP5292390B2 (ja) 2007-08-07 2008-08-06 アンドロゲン受容体調節剤としてのピロリジン−２−オン誘導体

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2007205966 2007-08-07
JP2007205966 2007-08-07
JP2007299658 2007-11-19
JP2007299658 2007-11-19
JP2010504096A JP5292390B2 (ja) 2007-08-07 2008-08-06 アンドロゲン受容体調節剤としてのピロリジン−２−オン誘導体
PCT/JP2008/064500 WO2009020234A2 (en) 2007-08-07 2008-08-06 Pyrrolidin-2 -one derivatives as androgen receptor modulator

Publications (3)

Publication Number Publication Date
JP2010535704A JP2010535704A (ja) 2010-11-25
JP2010535704A5 true JP2010535704A5 (https=) 2011-09-22
JP5292390B2 JP5292390B2 (ja) 2013-09-18

Family

ID=40329363

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010504096A Expired - Fee Related JP5292390B2 (ja) 2007-08-07 2008-08-06 アンドロゲン受容体調節剤としてのピロリジン−２−オン誘導体

Country Status (34)

Country Link
US (2) US8420694B2 (https=)
EP (1) EP2176220B1 (https=)
JP (1) JP5292390B2 (https=)
KR (1) KR20100049644A (https=)
CN (1) CN101821235B (https=)
AR (1) AR067823A1 (https=)
AU (1) AU2008284662B2 (https=)
BR (1) BRPI0814957B8 (https=)
CA (1) CA2695852C (https=)
CL (1) CL2008002313A1 (https=)
CO (1) CO6160326A2 (https=)
CR (1) CR11266A (https=)
CY (1) CY1114067T1 (https=)
DK (1) DK2176220T3 (https=)
DO (1) DOP2010000053A (https=)
EA (1) EA017429B1 (https=)
ES (1) ES2406685T3 (https=)
GE (1) GEP20125571B (https=)
HR (1) HRP20130374T1 (https=)
JO (1) JO2864B1 (https=)
MA (1) MA31639B1 (https=)
ME (1) ME01579B (https=)
MX (1) MX2010001484A (https=)
MY (1) MY159910A (https=)
NZ (1) NZ583624A (https=)
PE (1) PE20090899A1 (https=)
PL (1) PL2176220T3 (https=)
PT (1) PT2176220E (https=)
RS (1) RS52812B (https=)
SI (1) SI2176220T1 (https=)
TN (1) TN2010000062A1 (https=)
TW (1) TWI418543B (https=)
WO (1) WO2009020234A2 (https=)
ZA (1) ZA201001289B (https=)

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ME01579B (me) * 2007-08-07 2014-09-20 Takeda Pharmaceuticals Co Derivati pirolidin-2-ona kao modulatori androgenskih receptora
US8268872B2 (en) 2008-02-22 2012-09-18 Radius Health, Inc. Selective androgen receptor modulators
CA2716320C (en) * 2008-02-22 2014-01-28 Radius Health, Inc. Selective androgen receptor modulators
PE20091653A1 (es) * 2008-03-26 2009-11-14 Takeda Pharmaceutical Derivados sustituidos de pirazol y su uso
AU2011212813B2 (en) 2010-02-04 2014-10-23 Radius Health, Inc. Selective androgen receptor modulators
HUE030072T2 (en) 2010-05-12 2017-04-28 Radius Health Inc Therapeutic prescriptions
US8642632B2 (en) 2010-07-02 2014-02-04 Radius Health, Inc. Selective androgen receptor modulators
US9133182B2 (en) 2010-09-28 2015-09-15 Radius Health, Inc. Selective androgen receptor modulators
EP2834216A1 (en) * 2012-04-04 2015-02-11 Catylix Inc. Selective androgen receptor modulators
EP3158995B1 (en) 2012-08-09 2018-05-23 Dynamis Therapeutics, Inc. Meglumine for reducing high triglyceride levels
KR102069008B1 (ko) * 2012-09-21 2020-02-11 메르크 파텐트 게엠베하 C-c 삼중 결합을 갖는 화합물 및 액정 혼합물에서 이의 용도
US9421264B2 (en) 2014-03-28 2016-08-23 Duke University Method of treating cancer using selective estrogen receptor modulators
ES3055185T3 (en) 2014-03-28 2026-02-10 Univ Duke Treatment of an estrogen receptor positive breast cancer using a selective estrogen receptor modulator
KR101597327B1 (ko) * 2014-04-24 2016-02-24 동아에스티 주식회사 옥사졸리딘계 화합물 및 이를 포함하는 선택적 안드로겐 수용체 효능제
CN103951688B (zh) * 2014-05-06 2016-04-20 成都安斯利生物医药有限公司 一种制备3,5-二氟-4-甲基苯硼酸的方法
MX389702B (es) 2016-06-22 2025-03-20 Ellipses Pharma Ltd Compuestos para usarse en el tratamiento de cancer de mama que expresa el receptor de androgenos (ar+).
JP7481115B2 (ja) 2017-01-05 2024-05-10 ラジウス ファーマシューティカルズ，インコーポレイテッド Ｒａｄ１９０１－２ｈｃｌの多形性形態
MX2020013713A (es) 2018-07-04 2021-03-02 Radius Pharmaceuticals Inc Formas polimorficas de rad1901-2hcl.
BR112021013557A2 (pt) 2019-01-11 2021-09-21 Grünenthal GmbH Amidas de pirrolidina substituídas iii
EP3924328A1 (en) 2019-02-12 2021-12-22 Radius Pharmaceuticals, Inc. Processes and compounds
CN110204505B (zh) * 2019-05-31 2023-02-03 荆门医药工业技术研究院 (s)-3-苄氧羰基-4-异丙基-2,5-恶唑烷二酮的制备工艺
US20230012570A1 (en) * 2019-11-20 2023-01-19 Medshine Discovery Inc. Bicyclic compound used as selective androgen receptor modulator

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DE4141399A1 (de) 1991-12-16 1993-06-17 Bayer Ag 4-(substituierte)amino-3-arylpyrrolinon-derivate
CN1129581C (zh) * 1998-09-22 2003-12-03 山之内制药株式会社 氰基苯基衍生物
US6258833B1 (en) 1999-12-23 2001-07-10 Icos Corporation Cyclic AMP-specific phosphodiesterase inhibitors
US7026500B2 (en) 2000-08-24 2006-04-11 University Of Tennessee Research Foundation Halogenated selective androgen receptor modulators and methods of use thereof
JP2002088073A (ja) 2000-09-08 2002-03-27 Yamanouchi Pharmaceut Co Ltd 抗アンドロゲン剤
FR2817472B1 (fr) 2000-12-06 2003-01-03 Oreal Composition de teinture d'oxydation a base de 1-(4-aminophenyl)pyrrolidines substituees au moins en position 2 et 3 et procede de teinture de mise en oeuvre
DK1463497T3 (da) 2001-12-06 2012-01-30 Gtx Inc Behandling af muskelsvind med selektive androgenreceptormodulatorer
JP4316232B2 (ja) 2001-12-28 2009-08-19 武田薬品工業株式会社 アンドロゲン受容体拮抗剤
AU2002367424A1 (en) * 2001-12-28 2003-07-24 Takeda Chemical Industries, Ltd. Androgen receptor antagonists
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PL1753417T3 (pl) 2004-06-07 2012-09-28 Univ Tennessee Res Found Selektywny modulator receptora androgenowego i jego zastosowania medyczne
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TW200724139A (en) 2005-05-05 2007-07-01 Warner Lambert Co Androgen modulators
PL1891038T3 (pl) 2005-05-13 2009-04-30 Lilly Co Eli Podstawione n-arylopirolidyny jako selektywne modulatory receptora androgenowego
JP5070054B2 (ja) 2005-08-01 2012-11-07 武田薬品工業株式会社 環状アミン化合物
US20090042857A1 (en) * 2006-02-20 2009-02-12 Masuo Yamaoka Novel Pharmaceutical
BRPI0713198A2 (pt) 2006-07-19 2012-10-16 Osurf Ohio State University Res Foundation modulares seletivos de receptores de androgênio, seus análogos e derivados, e seus usos
KR20090034395A (ko) * 2006-07-26 2009-04-07 노파르티스 아게 운데카프레닐 피로포스페이트 합성효소의 억제제
JP5241507B2 (ja) 2006-11-30 2013-07-17 武田薬品工業株式会社 環状アミン化合物
ME01579B (me) * 2007-08-07 2014-09-20 Takeda Pharmaceuticals Co Derivati pirolidin-2-ona kao modulatori androgenskih receptora

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