JP2010534227A5 - - Google Patents
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- Publication number
- JP2010534227A5 JP2010534227A5 JP2010517450A JP2010517450A JP2010534227A5 JP 2010534227 A5 JP2010534227 A5 JP 2010534227A5 JP 2010517450 A JP2010517450 A JP 2010517450A JP 2010517450 A JP2010517450 A JP 2010517450A JP 2010534227 A5 JP2010534227 A5 JP 2010534227A5
- Authority
- JP
- Japan
- Prior art keywords
- carbon
- hydrogen atom
- oxime
- carbon bond
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims description 17
- 230000003078 antioxidant effect Effects 0.000 claims description 11
- 239000003963 antioxidant agent Substances 0.000 claims description 10
- 150000001875 compounds Chemical class 0.000 claims description 9
- QNTASHOAVRSLMD-GYKMGIIDSA-N n-[(8s,9s,10r,13r,14s,17r)-10,13-dimethyl-17-[(2r)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-ylidene]hydroxylamine Chemical class C1CC2=CC(=NO)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 QNTASHOAVRSLMD-GYKMGIIDSA-N 0.000 claims description 5
- 150000002923 oximes Chemical class 0.000 claims description 3
- 230000036620 skin dryness Effects 0.000 claims description 2
- 230000037393 skin firmness Effects 0.000 claims description 2
- 230000037303 wrinkles Effects 0.000 claims description 2
- 239000011203 carbon fibre reinforced carbon Substances 0.000 claims 12
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 12
- 239000002253 acid Substances 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 150000007513 acids Chemical class 0.000 claims 3
- -1 cholestane-3-one oxime Chemical class 0.000 claims 3
- 150000002148 esters Chemical class 0.000 claims 3
- 125000003544 oxime group Chemical group 0.000 claims 3
- 239000002537 cosmetic Substances 0.000 claims 2
- 235000013305 food Nutrition 0.000 claims 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 239000003755 preservative agent Substances 0.000 claims 2
- 230000002335 preservative effect Effects 0.000 claims 2
- PESKGJQREUXSRR-UHFFFAOYSA-N 5beta-cholestanone Natural products C1CC2CC(=O)CCC2(C)C2C1C1CCC(C(C)CCCC(C)C)C1(C)CC2 PESKGJQREUXSRR-UHFFFAOYSA-N 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 235000015872 dietary supplement Nutrition 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 125000000468 ketone group Chemical group 0.000 claims 1
- 230000036542 oxidative stress Effects 0.000 claims 1
- 230000009759 skin aging Effects 0.000 claims 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 230000003389 potentiating effect Effects 0.000 description 2
- 230000032683 aging Effects 0.000 description 1
- NYOXRYYXRWJDKP-GYKMGIIDSA-N cholest-4-en-3-one Chemical class C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 NYOXRYYXRWJDKP-GYKMGIIDSA-N 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 238000005502 peroxidation Methods 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0705426A FR2919180B1 (fr) | 2007-07-25 | 2007-07-25 | Utilisation d'au moins un derive oxime de la cholest-4-en-3-one comme antioxydants |
| PCT/FR2008/001101 WO2009044010A2 (fr) | 2007-07-25 | 2008-07-24 | Utilisation d'au moins un dérivé oxime de la cholest-4-èn-3-one comme antioxydants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010534227A JP2010534227A (ja) | 2010-11-04 |
| JP2010534227A5 true JP2010534227A5 (cg-RX-API-DMAC7.html) | 2011-09-08 |
Family
ID=39167758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010517450A Pending JP2010534227A (ja) | 2007-07-25 | 2008-07-24 | 少なくとも１つのコレスト−４−エン−３−オンオキシム誘導体の酸化防止剤としての使用 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20100267680A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2173198A2 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2010534227A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008306838A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0814580A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2697125A1 (cg-RX-API-DMAC7.html) |
| FR (1) | FR2919180B1 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2010000915A (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ582646A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2475052C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009044010A2 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA201000192B (cg-RX-API-DMAC7.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2874923B1 (fr) * | 2004-09-07 | 2006-10-27 | Trophos Sa | Application a titre de medicaments de derives du 3, 5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation |
| FR2919182B1 (fr) * | 2007-07-25 | 2009-11-13 | Trophos | Utilisation d'au moins un derive oxime du 3,5-seco-4-nor-cholestane comme antioxydants |
| FR2979239A1 (fr) | 2011-08-25 | 2013-03-01 | Trophos | Liposome comprenant au moins un derive de cholesterol |
| MY187342A (en) * | 2016-11-15 | 2021-09-22 | Univ Hong Kong Baptist Univ | Skin-protection composition containing dendrobium-based ingredients |
| CN108113996A (zh) * | 2016-11-29 | 2018-06-05 | 中国人民解放军军事医学科学院毒物药物研究所 | 一种用于化学毒剂防护的水溶性皮肤防护剂及其制备方法和用途 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU487923A1 (ru) * | 1973-07-04 | 1975-10-15 | Ордена Трудового Красного Знамени Институт Кристаллографии Им.А.В.Шубникова | Стабильна жидкокристаллическа смесь |
| JPS61148111A (ja) * | 1984-12-21 | 1986-07-05 | Ichimaru Fuarukosu Kk | 発毛促進剤 |
| FR2581542B1 (fr) | 1985-05-07 | 1988-02-19 | Oreal | Compositions topiques destinees au traitement de la peau a base de derives de l'acide salicylique |
| DE19834812A1 (de) * | 1998-08-01 | 2000-02-03 | Beiersdorf Ag | Verwendung von Sterolderivaten in kosmetischen und dermatologischen Zubereitungen zur Stärkung der Barrierefunktion der Haut |
| ES2388669T3 (es) * | 2003-03-11 | 2012-10-17 | Trophos | Aplicación como medicamentos de los dreivados de colest-4-en-3-ona, composiciones farmacéuticas que los contienen y nuevos derivados |
| FR2874923B1 (fr) * | 2004-09-07 | 2006-10-27 | Trophos Sa | Application a titre de medicaments de derives du 3, 5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation |
| US20060198809A1 (en) * | 2005-03-04 | 2006-09-07 | Woodridge Labs, Inc. | Gamma-amino butyric acid composition |
| FR2894968B1 (fr) * | 2005-12-20 | 2008-02-22 | Trophos Sa | Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation |
| FR2898272B1 (fr) * | 2006-03-09 | 2008-07-04 | Trophos Sa | Utilisation de derives du 3,5-seco-4-nor-cholestrane pour l'obtention d'un medicament cytoprotecteur |
| FR2899108B1 (fr) * | 2006-03-31 | 2012-02-03 | Trophos | Utilisation de derives du cholest-4-en-3-one pour l'obtention d'un medicament cytoprotecteur |
| FR2914188B1 (fr) * | 2007-03-28 | 2012-06-22 | Trophos | Nouvelle composition a base d'oxime de cholest-4-en-3-one |
| FR2919182B1 (fr) * | 2007-07-25 | 2009-11-13 | Trophos | Utilisation d'au moins un derive oxime du 3,5-seco-4-nor-cholestane comme antioxydants |
| US20100310674A1 (en) * | 2007-10-30 | 2010-12-09 | Trophos | Novel composition for treating the side effects of anticancer treatments |
| FR2934596B1 (fr) * | 2008-07-30 | 2015-04-10 | Trophos | Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation |
| FR2940650B1 (fr) * | 2008-12-29 | 2017-01-27 | Trophos | Nouveaux derives d'oxime du 3,5-seco-4-nor-cholestane, compositions pharmaceutiques les renfermant,et procede de preparation |
-
2007
- 2007-07-25 FR FR0705426A patent/FR2919180B1/fr not_active Expired - Fee Related
-
2008
- 2008-07-24 RU RU2010106614/13A patent/RU2475052C2/ru not_active IP Right Cessation
- 2008-07-24 MX MX2010000915A patent/MX2010000915A/es active IP Right Grant
- 2008-07-24 JP JP2010517450A patent/JP2010534227A/ja active Pending
- 2008-07-24 NZ NZ582646A patent/NZ582646A/xx not_active IP Right Cessation
- 2008-07-24 EP EP08836563A patent/EP2173198A2/fr not_active Withdrawn
- 2008-07-24 AU AU2008306838A patent/AU2008306838A1/en not_active Abandoned
- 2008-07-24 CA CA2697125A patent/CA2697125A1/fr not_active Abandoned
- 2008-07-24 BR BRPI0814580-6A2A patent/BRPI0814580A2/pt not_active IP Right Cessation
- 2008-07-24 WO PCT/FR2008/001101 patent/WO2009044010A2/fr not_active Ceased
- 2008-07-24 US US12/670,459 patent/US20100267680A1/en not_active Abandoned
-
2010
- 2010-01-11 ZA ZA2010/00192A patent/ZA201000192B/en unknown
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